EMPLOYMENT AGREEMENT

         THIS EMPLOYMENT AGREEMENT (the "Agreement"), made this 9th day of
October, 1998, is entered into by Palatin Technologies, Inc., a Delaware
corporation with its principal place of business at 214 Carnegie Center, Suite
100, Princeton, New Jersey 08540 (the "Company"), and Carl Spana, residing at
117 Winnebago Road, Yonkers, New York 10710 (the "Employee").

         The Company desires to employ the Employee, and the Employee desires to
be employed by the Company. In consideration of the mutual covenants and
promises contained herein, and other good and valuable consideration, the
receipt and sufficiency of which are hereby acknowledged by the parties hereto,
the parties agree as follows:

         1. Term of Employment. The Company hereby agrees to employ the
Employee, and the Employee hereby accepts employment with the Company, upon the
terms set forth in this Agreement, for the period commencing on September 11,
1998 (the "Commencement Date") and ending on September 10, 2001 (such period, as
it may be extended, the "Employment Period"), unless sooner terminated in
accordance with the provisions of Section 4.

         2.       Title; Capacity.

                  2.1 The Employee shall serve as Executive Vice President and
Chief Technology Officer or in such other position as the Company or its Board
of Directors (the "Board") may determine from time to time, with powers and
duties as may be determined, from time to time, by the Board. The Employee shall
be based at the Company's headquarters in Princeton, New Jersey.

 


                  2.2 The Employee hereby accepts such employment and agrees to
undertake the duties and responsibilities inherent in such position and such
other duties and responsibilities as the Board or its designee shall from time
to time reasonably assign to him. The Employee agrees to devote substantially
his entire business time, attention and energies to the business and interests
of the Company during the Employment Period. Any outside activities will be
reviewed with the Company in advance to ensure that such activities are not in
conflict with the Employee's obligations to the Company. The Employee agrees to
abide by the rules, regulations, instructions, personnel practices and policies
of the Company and any changes therein which may be adopted from time to time by
the Company. The Employee acknowledges receipt of copies of all such rules and
policies committed to writing as of the date of this Agreement.

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         3. Compensation and Benefits. During the Employment Period, unless
sooner terminated in accordance with the provisions of Section 4, the Employee
shall receive the following compensation and benefits:

                  3.1 Salary. The Company shall pay the Employee, in equal
semi-monthly installments or otherwise in accordance with the Company's standard
payroll policies as such policies may exist from time to time, an annual base
salary of $176,000. Such salary shall be subject to review thereafter, as
determined by the Company's Compensation Committee and approved by the Board, on
an annual basis on June 15 of each year, but the Board shall not decrease the
Employee's annual base salary at any such annual review.

                  3.2 Cash Performance Bonus. The Company shall pay the Employee
bonus compensation of up to one year's base salary (which base salary shall not
be less than $176,000 per year) in an amount to be decided by the Company's
Compensation Committee and approved by the Board, payable annually, no later
than March 31 of each year during the Employment Period. Such performance bonus
compensation shall be based upon, inter alia, yearly objectives mutually agreed
upon by and between the Employee and the Company.

                  3.3 Stock Options. As additional compensation for services
rendered, the Company grants to the Employee the right and option to purchase
all or any part of an aggregate of 50,000 shares of the Company's Common Stock


                                      -3-


(the "Option"), subject to the vesting schedule set forth in subparagraph c
hereof and the adjustments set forth in subparagraph g hereof, which Option is a
nonqualified stock option. The Option is in all respects limited and conditioned
as provided hereunder.

                  (a) Purchase Price. Except as otherwise provided in
         subparagraph g hereof, the purchase price (the "Option Price") of the
         shares covered by the Option ("Option Shares") shall be the closing
         price of the Company's Common Stock on the National Association of
         Securities Dealers Automated Quotation System (Nasdaq) on September 11,
         1998, to wit: $2.50.

                  (b) Option Term. Except as otherwise provided herein, the
         Option shall expire on the first to occur of: (i) ninety (90) days
         following the Employee's termination of employment with the Company, or
         (ii) September 11, 2008.

                  (c)      Exercise of Option.

                           (i) Except as otherwise provided herein, the right of
         the Employee to exercise the Option is conditioned upon the Employee:
         (A) being in the employ of the Company, whether pursuant to this
         Agreement or otherwise, or (B) serving as a director of the Company.

                           (ii) The Option shall vest (except as otherwise
         provided herein): (A) on the Commencement Date with respect to the
         first 33% of the Option Shares, (B) on the first anniversary of the
         Commencement Date (i.e., September 11) (the "Anniversary Date") with


                                      -4-


         respect to the second 33% of the Option Shares, and (C) on the second
         Anniversary Date with respect to the remaining 34% of the Option
         Shares.

                           (iii) The Option may be exercised, to the extent
         vested, in whole or in part, at any time or times prior to the
         expiration or other termination thereof.

                  (d)      Method Of Exercising Option.

                           (i) The Option may be exercised by giving written
         notice, in form substantially as set forth in Exhibit 1 hereof, to the
         Company at its principal office, specifying the number of Option Shares
         to be purchased and accompanied by payment in full of the aggregate
         purchase price for the Shares. Only full Shares shall be delivered and
         any fractional share which might otherwise be deliverable upon exercise
         of an Option granted hereunder shall be forfeited.

                           (ii) The purchase price shall be payable in cash or
                           its equivalent. 

                           (iii) Upon receipt of such notice and payment, 
         the Company, within three (3) business days after Exercise, shall
         deliver or cause to be delivered a certificate or certificates
         representing  the Shares with respect to which the Option is exercised.
         The certificate or certificates for such Shares shall be registered in
         the name of the person exercising the Option (or, if the Employee shall
         so request  in the  notice exercising the Option, in the name of the


                                      -5-


         Employee and his spouse, jointly, with right of survivorship) and shall
         be delivered  as  provided  above to or upon the written order of the
         person exercising the Option.  In the event the Option is exercised by
         any person after the death or Legal  Disability of the Employee, such
         notice shall be accompanied by appropriate proof of the right of such
         person to exercise the Option. All Shares purchased upon the exercise
         of the Option as provided herein shall be fully paid and nonassessable
         by the Company.

                  (e) Non-transferability of Option. The Option is not
         assignable or transferable, in whole or in part, by the Employee,
         otherwise than by will or by the laws of descent and distribution.
         During the lifetime of the Employee, the Option shall be exercisable
         only by the Employee or, in the event of his Legal Disability, by his
         legal representative.

                  (f) Withholding of Taxes. The obligation of the Company to
         deliver Shares upon the exercise of any Option shall be subject to any
         applicable federal, state and local tax withholding requirements.

                  (g) Adjustments. The number of Option Shares and the Option
         Price shall be adjusted as set forth herein:

                           (i) In the event that a stock dividend shall be
         declared on the Common Stock payable in shares of the Common Stock, the
         Option Shares shall be adjusted by adding to each Option Share the


                                      -6-


         number of shares which would be distributable thereon if such Option
         Share had been outstanding on the date fixed for determining the
         shareholders entitled to receive such stock dividend.

                           (ii) In the event that the outstanding shares of the
         Common Stock shall be changed into or exchanged for a different number
         or kind of shares of stock or other securities of the Company whether
         through recapitalization, stock split, combination of shares, or
         otherwise, then there shall be substituted for each Option Share the
         number and kind of shares of stock or the securities into which each
         outstanding share of the Common Stock shall be so changed or for which
         each such share shall be exchanged.

                           (iii) In the event that the outstanding shares of the
         Common Stock shall be changed into or exchanged for shares of stock or
         other securities of another corporation, whether through
         reorganization, sale of assets, merger or consolidation in which the
         Company is the surviving corporation, then there shall be substituted
         for each Option Share the number and kind of shares of stock or the
         securities into which each outstanding share of the Common Stock shall
         be so changed or for which each such share shall be exchanged.

                           (iv) In the event that any sale of shares of Common
         Stock (except any such sale made pursuant to any right, option, warrant
         or convertible security outstanding prior to the date of this


                                      -7-


         Agreement), or the issuance of any rights, options, or warrants to
         subscribe for or purchase Common Stock (or securities convertible into
         or exchangeable for Common Stock) occurs after the date of this
         Agreement, which sale or issuance, in the aggregate, will increase the
         number of shares of Common Stock outstanding during the Term by Forty
         percent (40%), then, upon each such sale or issuance, the Employee
         shall be issued additional Option Shares such that, when the additional
         Option Shares are aggregated with the Option Shares heretofore owned by
         the Employee, the Employee has the right to purchase, at the same times
         set forth in paragraph 4(c), the same percentage of Common Stock at the
         same price per share as the Employee maintained prior to such sale or
         issuance.

                  (h) Share Ownership. Neither the Employee nor the Employee's
         legal representatives nor the executors or administrators of his estate
         shall be or be deemed to be the holder of any share of Common Stock
         covered by an Option unless and until a certificate for such share
         shall have been issued.

                  3.4 Fringe-Benefits. The Employee shall be entitled to
participate in all bonus and benefit programs that the Company establishes and
makes available to its employees, if any, to the extent that the Employee's
position, tenure, salary, age, health and other qualifications make him eligible
to participate. The Employee shall also be entitled to holidays and annual


                                      -8-


vacation leave in accordance with the Company's policy as it exists from time to
time.

                  3.5 Reimbursement of Expenses. The Company shall reimburse the
Employee for all reasonable travel, entertainment and other expenses incurred or
paid by the Employee in connection with, or related to, the performance of his
duties, responsibilities or services under this Agreement, upon presentation by
the Employee of documentation, expense statements, vouchers and/or such other
supporting information as the Company may request, provided, however, that the
amount available for such travel, entertainment and other expenses may be fixed
in advance by the Board.

                  3.6 Insurance. The Employee will be covered under the
Company's Directors' and Officers' liability insurance to the same extent the
Company's directors and officers are covered.

         4. Employment Termination. The employment of the Employee by the
Company pursuant to this Agreement shall terminate upon the occurrence of any of
the following:

                  4.1 Expiration of the Employment Period in accordance with
Section 1; 

                  4.2 At the election of the Company, for Cause (as defined in
Section 7), immediately upon written notice by the Company to the Employee, 
which notice of termination shall have been approved by a majority of the Board;

                                      -9-


                  4.3 Immediately upon the death or determination of Legal
Disability (as defined in Section 7) of the Employee;

                  4.4 At the election of the Employee, for Good Reason (as
defined in Section 7), immediately upon written notice by the Employee to the
Company;

                  4.5 At the election of the Employee, within twelve (12) months
following a Change in Control (as defined in Section 7), immediately upon
written notice by the Employee to the Company;

                  4.6 At the election of either party, upon not less than thirty
(30) days' prior written notice of termination (the "Notice of Termination").

         5.       Effect of Termination.

                  5.1 Termination for Cause or at Election of the Employee other
than for Good Reason or due to a Change in Control. If, prior to the expiration
of this Agreement, the Employee's employment is terminated for Cause pursuant to
Section 4.2 (except in the case where such termination occurs within 12 months
following a Change in Control), or at the election of the Employee pursuant to
Section 4.6 other than for Good Reason or due to a Change in Control,

                  (a) the Company shall pay to the Employee the base salary and
         benefits otherwise payable to him under Section 3 through the last day
         of his actual employment by the Company (the "Date of Termination");

                                      -10-


                  (b) the Employee shall cease to have the right to exercise any
         options to purchase shares of capital stock of the Company previously
         granted to the Employee pursuant to any stock option plan or other
         employee benefit plan with the Company, regardless of the extent to
         which they have vested, on or after the Date of Termination.

                  5.2      Termination by Reason of the Employee's Death or 
Legal Disability.  If, prior to the expiration of this Agreement, the Employee's
employment is terminated by the Employee's death or Legal Disability pursuant
to Section 4.3,

                  (a) the Company shall, no later than the fifth business day
         following the death or determination of Legal Disability (the "Date of
         Termination"), pay to the Employee, or in the case of the Employee's
         death, to the estate of the Employee,

                           (i) the Employee's base salary and benefits otherwise
         payable to him through the Date of Termination, and

                           (ii) an amount equal to the greater of the aggregate
         base salary payments which the Employee would have received for a
         six-month period after the Date of Termination if such termination had
         not occurred, or $88,000, and

                  (b) all options to purchase shares of capital stock of the
         Company previously granted to the Employee pursuant to any stock option


                                      -11-


         plan or other employee benefit plan with the Company which have not
         vested at such time but which would have vested on and prior to the
         next Anniversary Date shall immediately vest and become fully
         exercisable in accordance with their terms for a period of ninety (90)
         days following the Date of Termination.

                  5.3 Termination for Any Other Reason. If, prior to the
expiration of this Agreement, the Employee's employment is terminated by the
Employee for circumstances constituting Good Reason pursuant to Section 4.4 or
due to a Change in Control pursuant to Section 4.5, or by the Company for any
basis other than for Cause (as defined in Section 7) or for Cause pursuant to
Section 4.2 if within twelve (12) months following a Change in Control, the
Company shall provide the Employee with the following benefits:

                  (a)      the Company shall pay to the Employee

                           (i) the Employee's base salary at the rate in effect
         at the time the Notice of Termination is given, benefits and all other
         compensation, including Employee's prorated cash performance bonus
         calculated by multiplying the Applicable Percentage (as defined in
         Section 7) by the greater of (x) the amount of the cash performance
         bonus awarded or paid to the Employee with respect to the Company's
         most recent full fiscal year for which such a bonus was awarded or paid
         to the Employee or (y) in the case of a Change in Control, the amount


                                      -12-


         of cash performance bonus awarded or paid to the Employee with respect
         to the Company's last full fiscal year prior to the Change in Control
         for which such a bonus was awarded or paid to the Employee, through the
         Date of Termination, no later than the fifth full day following the
         Date of Termination, plus all other amounts to which the Employee is
         entitled under any compensation plan of the Company at the time such
         payments are due and

                           (ii) if the Employee so elects, in lieu of his right
         to continue to receive deferred compensation under any deferred
         compensation plan of the Company then in effect, no later than the
         fifth full day following the Date of Termination, a lump-sum amount, in
         cash, equal to the deferred amounts together with any earnings credited
         on such amounts under such plan;

                  (b)      the Company will pay as severance to the Employee an
         amount equal to the sum of 

                           (i) the greatest of (x) the aggregate Salary payments
         which the Employee would have received during the balance of the Term
         if such termination had not occurred, (y) in the case of a Change in 
         Control, the aggregate Salary payments which the Employee would have 
         received during the balance of the Term based on the Employee's 
         annual base salary in effect immediately prior to the Change in 


                                      -13-


         Control, or (z) an amount equal to the Employee's highest annual 
         base salary achieved while employed by the Company, plus

                           (ii) the greater of (x) the amount of the cash
         performance bonus awarded or paid to the Employee with respect to the
         Company's most recent full fiscal year for which such a bonus was
         awarded or paid to the Employee or (y) in the case of a Change in
         Control, the amount of cash performance bonus awarded or paid to the
         Employee with respect to the Company's last full fiscal year prior to
         the Change in Control for which such a bonus was awarded or paid to the
         Employee;

                  (c) all options to purchase shares of capital stock of the
         Company previously granted to the Employee pursuant to any stock option
         plan or other employee benefit plan with the Company which have not
         vested at such time shall immediately vest and become fully exercisable
         in accordance with their terms for a period of ninety (90) days
         following the Date of Termination;

                  (d) for a one-year period after the Date of Termination, the
         Company shall arrange to provide the Employee with life, disability,
         dental, accident, travel and group health insurance benefits
         substantially similar to those which the Employee was receiving
         immediately prior to the Notice of Termination. Notwithstanding the
         foregoing, the Company shall not provide any benefit otherwise


                                      -14-


         receivable by the Employee pursuant to this paragraph (d) if an
         equivalent benefit is actually received by the Employee during the
         one-year period following the Date of Termination and any such benefit
         actually received by the Employee shall be reported to the Company; and

                  (e) for a six-month period after the Date of Termination, the
         Company shall reimburse the Employee for reasonable fees and expenses
         incurred by him for the purpose of locating employment in an amount
         mutually agreed upon by and between the Employee and the Company,
         including the fees and expenses of consultants and other persons
         retained by him for such purpose, promptly upon receipt by the Company
         of satisfactory evidence of payment of such fees and expenses.

                  5.4 No Requirement to Mitigate. The Employee shall not be
required to mitigate the amount of any payment provided for herein by seeking
other employment or otherwise.

                  5.5  Survival.  The provisions of Sections 5, 6, 7, 8 and 9
shall survive the termination of this Agreement.

         6. Withholding and Deductions. All payments hereunder shall be subject
to withholding and to such other deductions as shall at the time of such payment
be required pursuant to any income tax or other law, whether of the United
States or any other jurisdiction, and, in the case of payments to the executors


                                      -15-


or administrators to the Employee's estate, the delivery to the Company of all
necessary tax waivers and other documents.

         7. Definitions. For purposes of this Agreement the following 
definitions apply:

                  7.1  "Cause" for  termination  shall mean the  occurrence  of
any of the following  circumstances:  

                   (a) a  good  faith  finding  by  the  Company  of the
         Employee's willful breach or habitual neglect or failure to perform the
         material duties which he is required to perform under the terms of this
         Agreement, materially fails to follow the reasonable directives or
         policies established by or at the direction of the Board, or conducts
         himself in a manner materially detrimental to the interests of the
         Company such that the Company sustains a material loss or injury as a
         result thereof and such breach or failure of performance is not cured
         within thirty (30) days of the delivery to the Employee of written
         notice thereof, which notice of breach or failure of performance shall
         have been approved by a majority of the Board,

                  (b) the willful breach by the Employee of Section 8 of this
         Agreement or any provision of any confidentiality, invention and
         non-disclosure, non-competition or similar agreement between the
         Employee and the Company, or

                  (c) the conviction of the Employee of, or the entry of a
         pleading of guilty or nolo contendere by the Employee to, any crime
         involving moral turpitude or any felony.

                                      -16-


                  7.2 "Legal Disability" shall mean the inability of the
Employee, by reason of illness, accident or other physical or mental disability,
for a period of 120 days, whether or not consecutive, during any 360-day period,
to perform the services contemplated under this Agreement. A determination of
disability shall be made by a physician satisfactory to both the Employee and
the Company; provided, however, that if the Employee and the Company do not
agree on a physician, the Employee and the Company shall each select a physician
and these two together shall select a third physician, whose determination as to
disability shall be binding on all parties.

                  7.3 "Good Reason" shall mean the occurrence of any of the
following circumstances, and the Company fails to cure such circumstances within
thirty (30) days of the delivery to the Company of written notice of such
circumstances:

                  (a)      any significant diminution in the Employee's duties
          and responsibilities as in effect on the Commencement Date;

                  (b) any reduction in the Employee's annual compensation as in
         effect on the Commencement Date or as the same may be increased from
         time to time;

                  (c) the failure of the Company to continue in effect any
         material compensation or benefit plan in which the Employee
         participates as in effect on the Commencement Date, unless an equitable


                                      -17-


         arrangement (embodied in an ongoing substitute or alternative plan) has
         been made with respect to such plan, or the failure by the Company to
         continue the Employee's participation therein (or in such substitute or
         alternative plan) on a basis not materially less favorable, both in
         terms of the amount of benefits provided and the level of the
         Employee's participation relative to other participants, as in effect
         on the Commencement Date or the failure by the Company to award cash
         bonuses to its executives in amounts substantially consistent with past
         practice in light of the Company's financial performance;

                  (d) the failure by the Company to continue to provide the
         Employee with benefits substantially similar to those enjoyed by the
         Employee under any of the Company's insurance, medical, health and
         accident, or disability plans in which the Employee was participating
         as in effect on the Commencement Date, the taking of any action by the
         Company which would directly or indirectly materially reduce any of
         such benefits, or the failure by the Company to provide the Employee
         with the number of paid vacation days to which he is entitled in
         accordance with the Company's normal vacation policy in effect on the
         Commencement Date or in accordance with any agreement between the
         Employee and the Company existing at that time;

                  (e) any purported termination of the Employee's employment
         which is not effected pursuant to a Notice of Termination satisfying


                                      -18-


         the requirements of Section 9, which purported termination shall not be
         effective for purposes of this Agreement.

                  7.4      "Change in Control" shall mean the occurrence of any
 of the following events:

                  (a)      any "person," as such term is used in Sections 13(d)

         and  14(d) of the Securities  Exchange Act of 1934, as amended (the
         "Exchange Act") (other than the Company, any trustee or other fiduciary
         holding securities under an employee benefit plan of the Company, or 
         any corporation owned directly or indirectly by the stockholders of the
         Company in substantially the same proportion as their ownership of 
         stock of the Company) is or becomes the "beneficial  owner" (as defined
         in Rule 13d-3  under the Exchange  Act), directly or indirectly, of
         securities of the Company representing 40% or more of the combined
         voting power of the Company's then outstanding securities;

                  (b) individuals who, as of the Commencement Date, constitute
         the Board (as of the Commencement Date, the "Incumbent Board") cease
         for any reason to constitute at least a majority of the Board, provided
         that any person becoming a director subsequent to the Commencement Date
         whose election, or nomination for election by the Company's
         stockholders, was approved by a vote of at least a majority of the


                                      -19-


         directors then comprising the Incumbent Board (other than an election
         or nomination of an individual whose initial assumption of office is in
         connection with an actual or threatened election contest relating to
         the election of the directors of the Company, as such terms are used in
         Rule 14a-11 of Regulation 14A under the Exchange Act) shall be, for
         purposes of this Agreement, considered as though such person were a
         member of the Incumbent Board;

                  (c) the stockholders of the Company approve a merger or
         consolidation of the Company with any other corporation, other than

                           (i) a merger or consolidation which would result in
         the voting securities of the Company outstanding immediately prior
         thereto continuing to represent (either by remaining outstanding or by
         being converted into voting securities of the surviving entity) more
         than 80% of the combined voting power of the voting securities of the
         Company or such surviving entity outstanding immediately after such
         merger or consolidation or

                           (ii) a merger or consolidation effected to implement
         a recapitalization of the Company (or similar transaction) in which no
         "person" (as hereinabove defined) acquires more than 50% of the
         combined voting power of the Company's then outstanding securities; or

                  (d) the stockholders of the Company approve a plan of complete
         liquidation of the Company or an agreement for the sale or disposition
         by the Company of all or substantially all of the Company's assets.

                                      -20-


                  7.5 "Applicable Percentage" means the percentage obtained by
dividing the number of full or partial months worked in the most recent fiscal
year for which the Employee has not been awarded or paid a cash performance
bonus by twelve.

         8.       Restrictive Covenants.

                  (a)      For the purposes of this Agreement:

                           (i) "Proprietary Information" means all information
         and know-how, whether or not in writing, of a private, secret or
         confidential nature concerning the company's business or financial
         affairs, including, without limitation, inventions, products,
         processes, methods, techniques, formulas, compositions, compounds,
         projects, developments, plans, research data, clinical data, financial
         data, personnel data, computer programs and customer and supplier
         lists.

                           (ii) "Competing Products" means any products or
         processes of any person or organization other than the Company in
         existence or under development, which are substantially the same, may
         be substituted for, or applied to substantially the same end use as the
         products or processes that the Company is developing or has developed


                                      -21-


         or commercialized during the time of the Employee's employment with the
         Company.

                           (iii) "Competing Organization" means any person or
         organization engaged in, or about to become engaged in, research or
         development, production, distribution, marketing or selling of a
         Competing Product.

                  (b) The Employee understands that information regarding the
         Company and its affiliates including, without limitation, Proprietary
         Information, is considered confidential to the Company and is of
         substantial commercial value to the Company. Any entrusting of such
         confidential information to the Employee by the Company is done so in
         reliance upon the confidential relationship arising from the terms of
         his employment with the Company. Therefore, in consideration of his
         employment with the Company,

                           (i) the Employee will not, during or after the
         Employment Period, disclose any such confidential information to any
         person, firm, corporation, association, or other entity for any reason
         or purpose whatsoever, except within the scope of his duties and
         responsibilities in the ordinary course of business, unless ordered to
         do so by a court or other tribunal or government agency with
         jurisdiction over the subject matter and Employee;

                           (ii) the Employee acknowledges that he has, on or
         prior to the date of the Agreement, executed and delivered to the
         Company a Non-Disclosure Agreement (the "Confidentiality Agreement")


                                      -22-


         and the Employee hereby affirms and ratifies his obligations
         thereunder; and

                           (iii) the Employee agrees that after termination by
         the Company for Cause pursuant to Section 4.2 (except in the case where
         such termination occurs within 12 months following a Change in
         Control), or by the Employee pursuant to Section 4.6 other than for
         Good Reason or due to a Change in Control, he will not render services
         of any nature, directly or indirectly, to any Competing Organization in
         connection with any Competing Product within such geographical
         territory as the Company and such Competing Organization are or would
         be in actual competition, for a period of eighteen (18) months,
         commencing on the Date of Termination, provided, however, the
         aforementioned restrictions shall not be applicable to activities in
         which the Employee was, and continued to be, engaged in on the
         Commencement Date. The Employee understands that services rendered to
         such Competing Organization may have the effect of supporting actual
         competition in various geographic areas, and may be prohibited by this
         Agreement regardless of the geographic area in which such services are
         physically rendered. The Company may, in its sole discretion, elect to
         waive, in whole or in part, the obligation set forth in the previous
         sentence, such waiver to be effective only if given in writing by the
         Company.



                                      -23-


                  (c) The Employee agrees that he will not, during the
         Employment Period and for a period of nine (9) months commencing on the
         Date of Termination, directly or indirectly employ, solicit for
         employment, or advise or recommend to any other person that they employ
         or solicit for employment, any person whom he knows to be an employee
         of the Company or any parent, subsidiary or affiliate of the Company.

                  (d) In the event a court of competent jurisdiction should find
         any provision in this Section 8 to be unfair or unreasonable, such
         finding shall not render such provision unenforceable, but, rather,
         this provision shall be modified as to subject matter, time and
         geographic area so as to render the entire Section valid and
         enforceable. 9. Notices. All notices required or permitted under this
         Agreement shall be in writing and shall

be deemed effective upon personal delivery or upon deposit in the United States
Post Office, by registered or certified mail, postage prepaid, addressed to the
other party at the address shown above, or at such other address or addresses as
either party shall designate to the other in accordance with this Section 9.

         10. Pronouns. Whenever the context may require, any pronouns used in
this Agreement shall include the corresponding masculine, feminine or neuter
forms, and the singular forms of nouns and pronouns shall include the plural,
and vice versa.



                                      -24-


         11. Entire Agreement. This Agreement, together with the Confidentiality
Agreement, constitutes the entire agreement between the parties and supersedes
all prior agreements and understandings, whether written or oral, relating to
the subject matter of this Agreement.

         12. Amendment. This Agreement may be amended or modified only by a
written instrument executed by both the Company and the Employee.

         13. Governing Law. This Agreement shall be construed, interpreted and
enforced in accordance with the laws of New Jersey, without regard to its
principles of conflict of laws.

         14. Successors and Assigns. This Agreement shall be binding upon and
inure to the benefit of both parties and their respective successors and
assigns, including any corporation with which or into which the Company may be
merged or which may succeed to its assets or business; provided, however, that
the obligations of the employee are unique and personal and shall not be
assigned by him.



                                      -25-


         15.      Waiver of Breach.

                  15.1 Waiver by the Company. No delay or omission by the
Company in exercising any right under this Agreement shall operate as a waiver
of that or any other right. A waiver or consent given by the Company on any one
occasion shall be effective only in that instance and shall not be construed as
a bar or waiver of any right on any other occasion. No waiver by the Company
shall be valid unless in a writing signed by an authorized officer of the
Company and approved by an absolute majority of the Board.

                  15.2 Waiver by the Employee. No delay or omission by the
Employee in exercising any right under this Agreement shall operate as a waiver
of that or any other right. A waiver or consent given by the Employee on any one
occasion shall be effective only in that instance and shall not be construed as
a bar or waiver of any right on any other occasion. No waiver by the Employee
shall be valid unless in a writing signed by the Employee.

         16.      Miscellaneous.

                  16.1 The captions of the sections of this Agreement are for
convenience of reference only and in no way define, limit or affect the scope or
substance of any section of this Agreement.

                  16.2 In case any provision of this Agreement shall be invalid,
illegal or otherwise unenforceable, the validity, legality and enforceability of
the remaining provisions shall be no way be affected or impaired thereby.

                                      -26-


         IN WITNESS WHEREOF, the parties hereto have executed this Agreement as
an instrument under seal as of the day and year set forth above.

                           PALATIN TECHNOLOGIES, INC.

                           By:  /s/ Edward J. Quilty
                              -----------------------
                           Name: Edward J. Quilty
                           Title: Chairman and Chief Executive Officer


                           EMPLOYEE

                           /s/ Carl Spana
                           --------------------------
                           Carl Spana









                                      -27-