As filed with the Securities and Exchange Commission on December 10, 1998. ================================================================================ Registration No. 333-64563 SECURITIES AND EXCHANGE COMMISSION Washington D.C. 20549 ---------- PRE-EFFECTIVE AMENDMENT NO. 2 TO FORM S-3 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 ---------- BIO-VASCULAR, INC. (Exact name of registrant as specified in its charter) Minnesota 41-1526554 (State or other jurisdiction (I.R.S. Employer Identification No.) of incorporation or organization) ------------- 2575 University Avenue St. Paul, Minnesota 55114 (651) 603-3700 (Address, including zip code, and telephone number, including area code, of registrant's principal executive offices) ---------- Connie L. Magnuson Vice President - Finance and Chief Financial Officer 2575 University Avenue St. Paul, Minnesota 55114 (651) 603-3700 (Name, address, including zip code, and telephone number, including area code, of agent for service) --------------- Copies to: Michael J. Kolar, Esq. Oppenheimer Wolff & Donnelly LLP 3400 Plaza VII, 45 South Seventh Street Minneapolis, Minnesota 55402 (612) 607-7000 --------------- Approximate date of commencement of proposed sale to the public: From time to time after the effective date of this Registration Statement. --------------- If the only securities being registered on this Form are being offered pursuant to dividend or interest reinvestment plans, please check the following box. [ ] If any of the securities being registered on this Form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Act of 1933, other than securities offered only in connection with dividend or interest reinvestment plans, check the following box. [x] If this Form is filed to register additional securities for an offering pursuant to Rule 462(b) under the Securities Act, please check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. [ ] If this Form is a post-effective amendment filed pursuant to Rule 462(c) under the Securities Act, check the following box and list the Securities Act registration statement number of the earlier effective registration statement for the same offering. [ ] If delivery of the prospectus is expected to be made pursuant to Rule 434, please check the following box. [ ] --------------- THE REGISTRANT HEREBY AMENDS THIS REGISTRATION STATEMENT ON SUCH DATE OR DATES AS MAY BE NECESSARY TO DELAY ITS EFFECTIVE DATE UNTIL THE REGISTRANT SHALL FILE A FURTHER AMENDMENT WHICH SPECIFICALLY STATES THAT THIS REGISTRATION STATEMENT SHALL THEREAFTER BECOME EFFECTIVE IN ACCORDANCE WITH SECTION 8(A) OF THE SECURITIES ACT OF 1933 OR UNTIL THE REGISTRATION STATEMENT SHALL BECOME EFFECTIVE ON SUCH DATE AS THE COMMISSION, ACTING PURSUANT TO SAID SECTION 8(A), MAY DETERMINE. ================================================================================ PART II INFORMATION NOT REQUIRED IN PROSPECTUS Item 16. Exhibits 2.1 Acquisition Agreement and Plan of Reorganization by and among Bio-Vascular, Inc., Jer-Neen Acquisition, Inc., Jer-Neen Manufacturing Co., Inc., George Nelson, Jr., Ronald Breckner, James Pfau, Willard Sykes and Catherine Sykes, dated July 31, 1998 (incorporated by reference to Exhibit 2.1 to the Company's Current Report on Form 8-K, dated July 31, 1998, as amended (File No. 0-13907)). 4.1 Restated Articles of Incorporation of the Company, as amended, (incorporated by reference to Exhibit 3.1 to the Company's Quarterly Report on Form 10-Q for the quarter ended April 30, 1997 (File No. 0-13907)). 4.2 Amended and Restated Bylaws of the Company (incorporated by reference to Exhibit 3.2 to the Company's Registration Statement on Form S-4 (File No. 33-74750)). 4.3 Form of Common Stock Certificate of the Company (incorporated by reference to Exhibit 4.1 to the Company's Registration Statement on Form 10 (File 0-13907)). 4.4 Rights Agreement, dated as of June 12, 1996, between Bio-Vascular, Inc. and American Stock Transfer & Trust Company, which includes as Exhibit A the form of Rights Certificate (incorporated by reference to Exhibit 4.1 to the Company's Current Report on Form 8-K dated June 12, 1996 (File No. 0-13907)). 5.1 Opinion and Consent of Oppenheimer Wolff & Donnelly LLP (filed herewith electronically). 23.1 Consent of PricewaterhouseCoopers LLP (filed herewith electronically).* 23.2 Consent of Oppenheimer Wolff & Donnelly LLP (included in Exhibit 5.1). 24.1 Power of Attorney (included on page II-4 of this Registration Statement).* - ---------- *Indicates item previously filed SIGNATURES Pursuant to the requirements of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-3 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of St. Paul and State of Minnesota, on December 10, 1998. By: /s/ Connie L. Magnuson -------------------------------- Connie L. Magnuson Vice President - Finance and Chief Financial Officer (Principal Financial and Accounting Officer) Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed by the following persons on December 10, 1998 in the capacities indicated. Signature Title --------- ----- * President, Chief Executive Officer and - ---------------------------- Director (Principal Executive Officer) M. Karen Gilles * Chairman of the Board and Director - ---------------------------- Timothy M. Scanlan * Director - ---------------------------- William G. Kobi * Director - ---------------------------- Richard W. Perkins * Director - ---------------------------- Anton R. Potami * Director - ---------------------------- Timothy M. Scanlan * Director - ---------------------------- Edward E. Strickland - ---------- * By: /s/ Connie L. Magnuson --------------------------- Connie L. Magnuson Attorney-in-fact II-2 BIO-VASCULAR, INC. EXHIBIT INDEX TO REGISTRATION STATEMENT ON FORM S-3 Item No. Description Method of Filing - -------- ----------- ---------------- 2.1 Acquisition Agreement and Plan of Reorganization by and among Bio-Vascular, Inc., Jer-Neen Acquisition, Inc., Jer-Neen Manufacturing Co., Inc., George Nelson, Jr., Ronald Breckner, James Pfau, Willard Sykes and Catherine Sykes, dated July 31, 1998.................................Incorporated by reference to Exhibit 2.1 to the Company's Current Report on Form 8-K, dated July 31, 1998, as amended (File No. 0-13907). 4.1 Restated Articles of Incorporation of the Company, as amended...........................Incorporated by reference to Exhibit 3.1 to the Company's Quarterly Report on Form 10-Q for the quarter ended April 30, 1997 (File No. 0-13907). 4.2 Amended and Restated Bylaws of the Company.......................................Incorporated by reference to Exhibit 3.2 to the Company's Registration Statement on Form S-4 (File No. 33-74750). 4.3 Form of Common Stock Certificate of the Company.......................................Incorporated by reference to Exhibit 4.1 to the Company's Registration Statement on Form 10 (File 0-13907). 4.4 Rights Agreement, dated as of June 12, 1996, between Bio-Vascular, Inc. and American Stock Transfer & Trust Company, which includes as Exhibit A the form of Rights Certificate...................................Incorporated by reference to Exhibit 4.1 to the Company's Current Report on Form 8-K dated June 12, 1996 (File No. 0-13907)). 5.1 Opinion and Consent of Oppenheimer Wolff & Donnelly LLP..................................Filed herewith electronically. 23.1 Consent of PricewaterhouseCoopers LLP.........Filed herewith electronically.* 23.2 Consent of Oppenheimer Wolff & Donnelly LLP...Included in Exhibit 5.1. 24.1 Power of Attorney.............................Included on page II-4 of this Registration Statement.* - ---------- *Indicates item previously filed