Exhibit 3.4

                                  AMENDMENT TO
             SECOND AMENDED AND RESTATED ARTICLES OF INCORPORATION,
                              AS AMENDED TO DATE,
                                       OF
                             MEDI-JECT CORPORATION



 1.  The name of this corporation is Medi-Ject Corporation, a Minnesota
     corporation.

 2.  The following amendment to the Second Amended and Restated Articles of
     Incorporation, as amended to date, of Medi-Ject Corporation was adopted by
     the Board of Directors of Medi-Ject Corporation by written action dated
     January 15, 1999, pursuant to Section 302A.402, Subdivision 3 of the
     Minnesota Business Corporation Act:

     FURTHER RESOLVED, that the Company's Second Amended and Restated
     Articles of Incorporation, as amended to date, is hereby amended as
     follows:

     The first sentence of Article III is hereby amended to read as follows:

        "The total number of shares of capital stock which the corporation is
        authorized to issue shall be 4,400,000 shares, consisting of 3,400,000
        shares of common stock, par value $.01 per share ("Common Stock"), and
        1,000,000 shares of preferred stock, par value $.01 per share
        ("Preferred Stock")."

 3.  The amendment will not adversely affect the rights or preferences of the
     holders of outstanding shares of any class or series and will not result in
     the percentage of authorized shares that remain unissued after such
     amendment exceeding the percentage of authorized shares that were issued
     before such amendment.

 4.  The document attached hereto as Exhibit A sets forth the resolutions duly
     approved by a majority of the members of the Board of Directors of Medi-
     Ject Corporation by written action dated January 15, 1999, which
     resolutions state the manner in which the Company's share combination will
     be effected.

 5.  The amendment has been adopted pursuant to Chapter 302A of the Minnesota
     Business Corporation Act.

     IN WITNESS WHEREOF, the undersigned, the Secretary of Medi-Ject
     Corporation, being duly authorized on behalf of Medi-Ject Corporation, has
     executed this document on this 280h day of January, 1999.


                                              /s/ Mark S. Derus
                                              --------------------------------
                                              Mark S. Derus, Secretary


                             MEDI-JECT CORPORATION


                             Officer's Certificate
                             ---------------------



          The undersigned, Mark S. Derus, hereby certifies that he is the duly
elected, qualified and acting Executive Vice President, Finance; Chief Financial
Officer; and Secretary of Medi-Ject Corporation, a Minnesota corporation (the
"Company"), and does further certify that:



 1.  Attached hereto as Exhibit A is a true, complete and correct copy of the
     resolutions duly adopted by the Board of Directors of the Company by
     written action dated January 15, 1999; such resolutions are the only
     resolutions adopted by the Board of Directors of the Company or any
     committee thereof relating to the matters contemplated therein; and such
     resolutions have not been amended, modified or rescinded and remain in full
     force and effect on the date hereof.



IN WITNESS WHEREOF, I have executed this Officer's Certificate this 28th day of
January, 1999.


                              /s/ Mark S. Derus
                              ------------------------------------
                              Mark S. Derus
                              Executive Vice President, Finance
                              Chief Financial Officer and Secretary


Exhibit A



                          EXCERPT FROM WRITTEN ACTION
                                       OF
                             THE BOARD OF DIRECTORS
                                       OF
                             MEDI-JECT CORPORATION


                             DATED JANUARY 15,1999




          NOW THEREFORE, BE IT RESOLVED, that the officers of the Company are,
and each of them is, hereby authorized and directed, for and on behalf of the
Company, to effectuate a one-for-five reverse stock split of the Common Stock
(the "Reverse Split").

          FURTHER RESOLVED, that January 28, 1999, shall be the record date for
the Reverse Split (the "Record Date").

          FURTHER RESOLVED, that (i) effective upon the Record Date, each five
shares of Common Stock issued and outstanding immediately prior to the Record
Date shall thereby and thereupon combine into one share of Common Stock, such
combination to occur without any further action by the holders thereof,
provided, however, that no fractional shares of Common Stock shall be issued as
a result of the Reverse Split, but in lieu thereof, each shareholder entitled to
receive a fractional share will be paid an amount in cash (without interest)
equal to the closing price of the Common Stock as reported on the Nasdaq
National Market on the Record Date; and (ii) stock certificates representing
shares of Common Stock issued and outstanding immediately prior to the Record
Date shall thereafter, automatically and without the necessity of presenting the
same for exchange, represent the number of shares (rounded down to the nearest
whole share) obtained by dividing the number of shares of Common Stock
represented by such certificates prior to the Record Date by five.

          FURTHER RESOLVED, that the Company's Second Amended and Restated
Articles of Incorporation, as amended to date, is hereby amended as follows:



                                       I.



          The first sentence of Article III is hereby amended to read as
follows:

          "The total number of shares of capital stock which the corporation is
     authorized to issue shall be 4,400,000 shares, consisting of 3,400,000
     shares of common stock, par value $.01 per share ("Common Stock"), and
     1,000,000 shares of preferred stock, par value $.01 per share ("Preferred
     Stock")."

          FURTHER RESOLVED, that the officers of the Company are hereby
authorized and directed to execute and file Articles of Amendment to the Second
Amended and Restated Articles of Incorporation, as amended to date, of the
Company with the Secretary of State of Minnesota reflecting the changes as
stated herein.



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          FURTHER RESOLVED, that appropriate adjustments and reservations of
shares be made to the Company's 1993 Stock Option Plan, as amended, the
Company's 1996 Stock Option Plan, as amended, and the Company's 1998 Stock
Option Plan for Non-Employee Directors (collectively, the "Plans") (i) to
decrease the number of shares purchasable under each option granted under the
Plans and outstanding on the date on which the Reverse Split is effected, (ii)
to decrease the number of shares reserved for issuance under the Plans and (iii)
to increase the exercise price per share of each such option.

          FURTHER RESOLVED, that, in light of the Reverse Split, appropriate
adjustments and reservations be made to options or other rights to purchase the
Common Stock that are outstanding on the date on which the Reverse Split is
effected (other than those issued under the Plans) (i) to decrease the number of
shares purchasable under such options or other rights, (ii) to decrease the
number of shares reserved for issuance upon the exercise of such options or
other rights and (iii) to increase the exercise price per share of each such
options or other rights.

          FURTHER RESOLVED, that the officers of the Company are, and each of
them hereby is, authorized and directed to take any action necessary or
appropriate to establish procedures for the issuance of replacement share
certificates from the authorized and unissued shares of the Company in order to
effect the Reverse Split, and each of the shares represented by such
certificates shall be validly issued, fully paid and non-assessable; provide ,
however, that until such time as a holder of a share certificate shall surrender
his or her certificate pursuant to such procedures, such outstanding
certificates shall be deemed to represent the number of whole shares of Common
Stock to which such holder shall be entitled upon the surrender thereof.

          FURTHER RESOLVED, that, for the purpose of the issuance of replacement
certificates as a result of the Reverse Split, Norwest Bank, Minnesota, National
Association, as transfer agent and registrar (the "Transfer Agent"), is hereby
authorized to record in its transfer records and to countersign as Transfer
Agent and Registrar replacement certificates for shares of Common Stock
resulting from the Reverse Split; and that the officers of the Company are, and
each of them hereby is, authorized to execute and deliver such instructions as
may be necessary or appropriate in connection with the issuance of replacement
shares in connection with the Reverse Split.

          FURTHER RESOLVED, that all actions taken by the officers of the
Company, or any of them, prior to the date hereof in order to accomplish the
intent and purposes of the foregoing resolutions are hereby ratified, approved
and confirmed.

          FURTHER RESOLVED, that the officers of the Company are, and each of
them hereby is, authorized and directed to take any action necessary or
appropriate to effect the Reverse Split, including the giving of any notices and
preparing and filing Articles of Amendment with the Minnesota Secretary of
State, Listing of Additional Shares form and such other forms necessary to
transfer the listing of the Common Stock from the Nasdaq National Market to the
Nasdaq SmallCap Market, and to execute any documents and take any other actions
necessary or advisable to carry out the intent of the foregoing resolutions.



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