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                                                                   EXHIBIT 10.32

                           EXCLUSIVE LICENSE AGREEMENT

        This Exclusive License Agreement (the "Agreement") is entered into as of
November 26, 2002 (the "Effective Date") by and between Matrix Technologies
Corporation, d/b/a Apogent Discoveries, a Delaware corporation, having a
principal place of business at 22 Friars Drive, Hudson, New Hampshire, 03051
("APOGENT"), and EXACT Sciences Corporation, a Delaware corporation having a
principal place of business at 63 Great Road, Maynard, Massachusetts 01754
("EXACT").

        In consideration of the mutual promises and conditions contained in this
Agreement, APOGENT and EXACT agree as follows:

                             ARTICLE 1 - DEFINITIONS

1.1     "Affiliate" shall mean any company, corporation or other business entity
        that is controlled by, controlling, or under common control with the
        subject company, corporation or other business. For this purpose
        "control" means direct or indirect beneficial ownership of at least
        fifty percent (50%) interest in the voting stock (or the equivalent) of
        the company, corporation or other business or having the right to
        direct, appoint or remove a majority of members of its board of
        directors (or their equivalents) or having the power to control the
        general management of the company, corporation or other business, by law
        or contract.

1.2     "APOGENT Technology" shall mean APOGENT's proprietary acrydite chemistry
        technology described and claimed in the Licensed Patents. APOGENT
        Technology expressly includes the Licensed Patents, Licensed Products,
        and the Licensed Process.

1.3     "EXACT Inventions" shall mean (a) all inventions, and all modifications,
        enhancements, changes, or improvements to APOGENT Technology that are
        conceived or reduced to practice solely by EXACT in the course of
        performing under this Agreement.

1.4     "EXACT Net Revenues" shall mean [CONFIDENTIAL TREATMENT REQUESTED]/*/
        other than revenues received by EXACT from a Sublicensee, from
        [CONFIDENTIAL TREATMENT REQUESTED]/*/

1.5     "Exclusive Field" shall mean [CONFIDENTIAL TREATMENT REQUESTED]/*/

1.6     "Non-Exclusive Field" shall mean any field, other than the Exclusive
        Field, in which [CONFIDENTIAL TREATMENT REQUESTED]/*/ is employed.

1.7     [CONFIDENTIAL TREATMENT REQUESTED]/*/ shall mean EXACT's proprietary
        [CONFIDENTIAL TREATMENT REQUESTED]/*/ technology [CONFIDENTIAL
        TREATMENT REQUESTED]/*/as disclosed in the U.S. patents
        and applications identified in Exhibit 1, all extensions thereof, and
        all reissue, reexamination, continuation, continuation-in-part,
        divisional, and foreign patents relating thereto.

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1.8     "Licensed Patents" shall mean, individually and collectively, (i) the
        U.S. patent(s) identified on Exhibit 2, attached hereto, and any
        reissues, reexaminations, and extensions thereof, and all foreign
        patents or applications corresponding to any of the foregoing; (ii) the
        U.S. patent applications identified on Exhibit 2, and all foreign
        patents or applications corresponding thereto; (iii) all
        non-provisional, continuation, continuation-in part, divisional and
        foreign applications that claim the priority, either directly or
        indirectly, to any Licensed Patents described in subsection (i) or (ii)
        above; and (iv) all United States and foreign patents issued on the
        Licensed Patents described in subsection (ii) or (iii) above, and all
        reissues, reexaminations and extensions thereof.

1.9     "Licensed Process" shall mean a process that, but for this license
        Agreement, would infringe a valid and enforceable claim in the Licensed
        Patents.

1.10    "Licensed Product" shall mean any product that is manufactured in
        reliance on the Licensed Process and that, but for this license
        Agreement, would infringe a valid and enforceable claim in the Licensed
        Patents.

1.11    "Party" or "Parties" shall mean APOGENT and/or EXACT, as the context
        requires.

1.12    "Result" means a test result per single patient derived from the use of
        a Licensed Product or the application of a Licensed Process. In
        determining the number of "Results" that are comprised in a kit that
        includes one or more Licensed Products or is to be used as part of a
        Licensed Process, the Results for purposes of this Agreement shall be
        that number of results or patient applications specified in the product
        labeling or inserts for such kit.

1.13    "Sublicensee" shall mean any entity to which EXACT has granted a
        sublicense of some or all of the rights conveyed to EXACT under this
        Agreement.

1.14    "Sublicensee Net Revenues" shall mean [CONFIDENTIAL TREATMENT
        REQUESTED]/*/

                    ARTICLE 2 - GRANT OF LICENSES; OWNERSHIP

2.1     EXCLUSIVE LICENSE GRANT. Subject to the terms and conditions of this
        Agreement, APOGENT grants to EXACT an exclusive, worldwide,
        royalty-bearing license under the Licensed Patents in the Exclusive
        Field, for use , to make, have made, use, offer to sell, sell and import
        Licensed Products and Licensed Processes. This license granted hereunder
        shall be exclusive, even as to APOGENT, within the Exclusive Field
        during the Term of this Agreement and shall include the right to
        sublicense as herein provided. This exclusive license may be converted
        to a non-exclusive license in accordance with Section 9.1 hereof.

2.2     NON-EXCLUSIVE LICENSE GRANT. Subject to the terms and conditions of this
        Agreement, APOGENT grants to EXACT a non-exclusive, worldwide,
        royalty-bearing license under the Licensed Patents in the Non-Exclusive
        Field, with the

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        right to sublicense as herein provided to make, have made, use, offer to
        sell, sell and import Licensed Products or Licensed Processes..

2.3     SUBLICENSING. EXACT shall have the right to sublicense the rights
        granted in Paragraph 2.1 and Paragraph 2.2 above solely for use with
        EXACT's [CONFIDENTIAL TREATMENT REQUESTED]/*/ to a Sublicensee, provided
        however, that no such sublicense shall be effective until the
        Sublicensee executes a written agreement with respect to which APOGENT
        is a named third-party beneficiary whereby the Sublicensee is bound,
        with respect to the license of the Licensed Process and the manufacture
        and sale of the Licensed Products, to terms that do not materially
        differ from the terms of this Agreement.

2.4     OWNERSHIP.

        2.4.1   EXACT OWNERSHIP. The Parties hereby acknowledge and agree that
                EXACT shall own and retain all right, title and interest in and
                to all EXACT Inventions.

        2.4.2   PRE-EXISTING TECHNOLOGY. All technology and intellectual
                property rights owned by a Party as of the Effective Date shall
                remain the property of such Party. Without limiting the
                foregoing, APOGENT shall be the sole owner of the APOGENT
                Technology, subject to the license granted hereby and such other
                licenses as APOGENT may, in its discretion, grant from time to
                time, and EXACT shall be the sole owner of the [CONFIDENTIAL
                TREATMENT REQUESTED]/*/ subject to the such licenses as EXACT
                may, in its discretion, grant from time to time. Neither party
                shall reverse engineer, copy or use the technology or inventions
                of the other party except as expressly contemplated by and
                permitted under this Agreement.

        2.4.3   NO IMPLIED LICENSES. Nothing in this Agreement shall be
                construed as granting any Party any right or license under any
                intellectual property rights, trademarks, or service marks of
                any other Party by implication, estoppel or otherwise, except as
                expressly provided otherwise in this Agreement.

                              ARTICLE 3 - ROYALTIES

3.1     ROYALTIES. During the Term, EXACT shall pay APOGENT royalties on the
        sale of the Licensed Process or a Licensed Product on a quarterly basis
        as follows:

        3.1.1   [CONFIDENTIAL TREATMENT REQUESTED]/*/ of EXACT Net Revenues
                received by EXACT during the applicable quarter, however, such
                royalty shall never be less than [CONFIDENTIAL TREATMENT
                REQUESTED]/*/

        3.1.2   [CONFIDENTIAL TREATMENT REQUESTED]/*/ of each Sublicensee Net
                Revenues, with respect to which royalties are payable to, and
                received by EXACT during the applicable quarter, however, such
                royalty shall never be less than [CONFIDENTIAL TREATMENT
                REQUESTED]/*/.

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        EXACT shall pay royalties due with respect to each calendar quarter
        hereunder within [CONFIDENTIAL TREATMENT REQUESTED]/*/

3.2     [CONFIDENTIAL TREATMENT REQUESTED]/*/ EXACT shall not be required to
        [CONFIDENTIAL TREATMENT REQUESTED]/*/. EXACT shall have primary
        obligation to [CONFIDENTIAL TREATMENT REQUESTED]/*/ however, APOGENT
        shall have the right to [CONFIDENTIAL TREATMENT REQUESTED]/*/. APOGENT's
        right to [CONFIDENTIAL TREATMENT REQUESTED]/*/ under this Section 3.2
        shall only apply in instances where [CONFIDENTIAL TREATMENT
        REQUESTED]/*/.

                      ARTICLE 4 - ROYALTY REPORTS; RECORDS

4.1     ROYALTY REPORTS. Within [CONFIDENTIAL TREATMENT REQUESTED]/*/ during the
        Term, EXACT shall deliver to APOGENT the royalty payment due pursuant to
        Section 3.1 hereof and a corresponding royalty report relating to the
        preceding calendar quarter. Each report shall include the following:

                (a) Deductions applicable to determining Net Revenues and
                Sublicensee Net Revenues during the relevant calendar quarter;
                and

                (b) Total royalties due to APOGENT for the calendar quarter.

                With each report, EXACT shall pay to APOGENT the royalties due
                and payable for such calendar quarter.

4.2     RECORD KEEPING.

        4.2.1   BOOKS AND RECORDS. EXACT shall keep true books of account in
                accordance with EXACT's own document retention policies relating
                to Net Revenues, Sublicensee Net Revenues and Licensed Product
                use manufacture and sale by EXACT and each Sublicensee. Such
                books and records shall be in accordance with generally accepted
                accounting principles consistently applied. EXACT shall keep
                such records at its principal place of business.

        4.2.2   INSPECTIONS. Upon ten (10) business days' prior written notice
                to EXACT, APOGENT may, at APOGENT's own expense, have EXACT's
                books and records inspected by a certified public accountant
                selected by APOGENT and reasonably acceptable to EXACT. Such
                inspections shall be during regular business hours and shall not
                be made more than once each calendar year, except in the case of
                misreported royalties, Net Revenues or Sublicensee Net Revenues.
                In conducting inspections under this paragraph 4.2.2, APOGENT's
                accountant may have access to only those records which are
                reasonably relevant to calculating royalties owed to APOGENT
                under Article 3. APOGENT shall bear the cost of any inspection
                under this Article 4.2.2, unless the inspection shows an
                underreporting or underpayment by any entity in excess of five
                percent

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                (5%) for any twelve month period, in which case EXACT shall pay
                the cost of the inspection as well as any additional sum due to
                APOGENT.

4.3     FORM OF PAYMENTS. EXACT shall make all payments due under this Agreement
        by check or wire transfer in United States funds.

4.4     CURRENCY CONVERSION. If any currency conversion is required in
        connection with any payment to APOGENT under this Agreement (for
        example, with respect to Sublicensee Net Revenues), the conversion will
        be made at the buying rate for the transfer of such other currency as
        quoted by THE WALL STREET JOURNAL, Eastern Edition, on the last business
        day of each calendar quarter in which such payments are accrued.

4.5     INTEREST. Any payment due to APOGENT under this Agreement that is not
        made when due will accrue interest beginning on the first day following
        the due date. The interest shall be compounded at the rate of one and
        one-half percent (1 1/2%) per month, compounded monthly until such
        overdue payment is received by APOGENT.

                           ARTICLE 5 - CONFIDENTIALITY

5.1     CONFIDENTIAL INFORMATION. During the Term, the Parties may exchange
        information from time to time that they consider to be confidential.
        "Confidential Information" hereunder shall, subject to Article 5.3, mean
        the substance of this Agreement and any information or materials that
        are disclosed by one Party (the "Discloser") to another Party (the
        "Recipient") whether orally, visually, or in tangible form, and all
        copies thereof. Tangible materials that disclose or embody Confidential
        Information shall be marked by Discloser as "Confidential,"
        "Proprietary" or the substantial equivalent thereof. Confidential
        Information that is disclosed orally or visually shall be identified by
        Discloser as confidential at the time of disclosure and reduced to a
        written summary by Discloser, which shall mark such summary as
        "Confidential," "Proprietary" or the substantial equivalent thereof, and
        deliver it to Recipient by the end of the month following the month in
        which disclosure occurs. Such information shall be treated as
        Confidential Information pending receipt of such summary.

5.2     TREATMENT OF CONFIDENTIAL INFORMATION. The Recipient of Confidential
        Information shall employ all reasonable efforts to maintain the secrecy
        and confidentiality of such Confidential Information, such efforts to be
        no less than the degree of care employed by the Recipient to preserve
        and safeguard its own Confidential Information. The information shall
        not be disclosed or revealed to anyone except employees of the Recipient
        who have a need to know the information and who have entered into a
        secrecy agreement with the Recipient under which such employees are
        required to maintain confidential the proprietary information of the
        Recipient and such employees shall be advised by the Recipient of the
        confidential nature of the Confidential Information and that the
        Confidential Information shall be treated accordingly. Each Sublicensee
        shall be bound, as a Recipient, not to disclose the Confidential
        Information of APOGENT, whether such Confidential Information is
        provided by APOGENT or by EXACT;

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        and both the Sublicensee and EXACT shall be jointly and severally liable
        for any breach of such obligation by the Sublicensee.

5.3     EXCEPTIONS. The Recipient's obligations under this Article 5 shall not
        extend to any part of the information that:

                (i)   can be demonstrated to have been in the public domain or
                      publicly known prior to the date of the disclosure; or

                (ii)  can be demonstrated from written records to have been in
                      the Recipient's possession or readily available to the
                      Recipient from another source not under obligation of
                      secrecy to the Discloser prior to the disclosure; or

                (iii) becomes part of the public domain or publicly known other
                      than as a result of any unauthorized act by the Recipient;
                      or

                (iv)  is demonstrated from contemporaneous written records to
                      have been developed by or for the Recipient without
                      reference to confidential information disclosed by the
                      Discloser; or

                (v)   is required to be disclosed by law, government regulation
                      or court order.

        However, the exception set forth in Section 5.3(v) shall only apply if,
        prior to making any legally required disclosure of the Discloser's
        Confidential Information, the Recipient notifies the Discloser and
        affords the Discloser a reasonable opportunity to defend against or
        limit such required disclosure.

5.4     INJUNCTION. In view of the difficulties of placing a monetary value on
        the Confidential Information, the Discloser shall be entitled to a
        preliminary and final injunction without the necessity of posting any
        bond or undertaking in connection therewith to prevent further breach of
        this Article 5 or further unauthorized use of its Confidential
        Information. This remedy is separate from any other remedy the Discloser
        may have.

5.5     TREATMENT UPON TERMINATION OF THE AGREEMENT. Upon the expiration or
        termination, for any reason, of this Agreement, or upon the demand of
        the Discloser at any time, Recipient shall return promptly to Discloser
        or destroy, at Discloser's option, all tangible materials that disclose
        or embody Confidential Information of the Discloser.

                   ARTICLE 6 - REPRESENTATIONS AND WARRANTIES

6.1     APOGENT REPRESENTATIONS AND WARRANTIES. APOGENT hereby represents and
        warrants to EXACT that:

        6.1.1   APOGENT is a corporation duly organized and validly existing
                under the name "Matrix Technologies Corporation" in the State of
                Delaware, and has all requisite power and authority to execute,
                deliver and perform its

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                obligations under this Agreement and to consummate the
                transactions contemplated hereby;

        6.1.2   This Agreement does not contravene or constitute a default under
                or violation of any provision of applicable law binding upon
                APOGENT or any agreement, commitment, instrument or other
                arrangement to which APOGENT is a party;

        6.1.3   To the knowledge of APOGENT, all necessary consents, approvals
                and authorizations of all governmental authorities and other
                persons required to be obtained in connection with entry into
                this Agreement have been obtained;

        6.1.4   APOGENT is in possession of and has conveyed in this Agreement
                all rights necessary for EXACT to practice and obtain the full
                benefit of the licenses granted to EXACT hereunder;

        6.1.5   To the knowledge of APOGENT, the use contemplated by this
                Agreement of the Licensed Process licensed hereby neither
                infringes nor violates any patent, copyright, trade secret,
                trademark or other proprietary right of any third party; and

        6.1.6   To the knowledge of APOGENT, there is no reason that the
                Licensed Patents are invalid or unenforceable

6.2     EXACT REPRESENTATIONS AND WARRANTIES. EXACT hereby represents and
        warrants to APOGENT that:

        6.2.1   EXACT is a corporation duly organized and validly existing under
                the laws of the State of Delaware and has all requisite
                corporate power and authority to execute, deliver and perform
                its obligations under this Agreement and to consummate the
                transactions contemplated hereby; and

        6.2.2   This Agreement does not contravene or constitute a default or
                violation of any provision of applicable law binding upon EXACT
                or any agreement, commitment or instrument to which EXACT is a
                party.

                           ARTICLE 7 - INDEMNIFICATION

7.1     INDEMNITY BY APOGENT. APOGENT shall indemnify, hold harmless and defend
        EXACT from and against any and all liability, damage, loss, cost or
        expense (including reasonable attorney's fees) incurred by or imposed
        upon EXACT in connection with any claims, suits, actions, demands,
        proceedings, causes of action or judgments resulting from or arising out
        of [CONFIDENTIAL TREATMENT REQUESTED]/*/. EXACT shall promptly notify
        APOGENT of any such claim(s) of which EXACT is aware. APOGENT
        [CONFIDENTIAL TREATMENT REQUESTED]/*/ shall [CONFIDENTIAL TREATMENT
        REQUESTED]/*/ provided, however, that EXACT shall have the right to
        [CONFIDENTIAL TREATMENT REQUESTED]/*/. In addition, EXACT shall have the
        right to [CONFIDENTIAL TREATMENT REQUESTED]/*/. EXACT agrees to provide
        APOGENT with [CONFIDENTIAL TREATMENT

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        REQUESTED]/*/. In the event a third-party asserts a claim for which
        EXACT may seek indemnification under this Section 7.1, APOGENT shall
        have the right to [CONFIDENTIAL TREATMENT REQUESTED]/*/. Further,
        APOGENT shall have no obligation to [CONFIDENTIAL TREATMENT
        REQUESTED]/*/. The obligation of APOGENT to [CONFIDENTIAL TREATMENT
        REQUESTED]/*/.

7.2     INDEMNITY BY EXACT. EXACT shall indemnify, hold harmless and defend
        APOGENT from and against any and all liability, damage, loss, cost or
        expense (including reasonable attorney's fees) incurred by or imposed
        upon APOGENT in connection with any claims, suits, actions, demands,
        proceedings, causes of action or judgments resulting from or arising out
        of [CONFIDENTIAL TREATMENT REQUESTED]/*/. APOGENT shall promptly notify
        EXACT of any such claim(s) of which APOGENT is aware. EXACT
        [CONFIDENTIAL TREATMENT REQUESTED]/*/ shall [CONFIDENTIAL TREATMENT
        REQUESTED]/*/ provided, however, that APOGENT shall have the right to
        [CONFIDENTIAL TREATMENT REQUESTED]/*/. In addition, APOGENT shall have
        the right to [CONFIDENTIAL TREATMENT REQUESTED]/*/ APOGENT agrees to
        provide EXACT with [CONFIDENTIAL TREATMENT REQUESTED]/*/.

                      ARTICLE 8 - DISCLAIMER OF WARRANTIES

8.1     NO OTHER WARRANTIES. EXCEPT AS EXPRESSLY PROVIDED HEREIN, NEITHER PARTY
        MAKES ANY WARRANTIES WITH RESPECT TO THE LICENSED PRODUCTS AND DISCLAIMS
        ALL OTHER WARRANTIES AND CONDITIONS, EXPRESS OR IMPLIED, INCLUDING THOSE
        OF MERCHANTABILITY, AND FITNESS FOR A PARTICULAR PURPOSE, OR ARISING
        FROM A COURSE OF DEALING, USAGE OR TRADE PRACTICE, TO THE EXTENT
        PERMITTED BY APPLICABLE LAW.

8.2     LIMITATION OF LIABILITY. EXCEPT AS EXPRESSLY PROVIDED HEREIN, NEITHER
        PARTY SHALL BE LIABLE TO THE OTHER PARTY WITH RESPECT TO MATTERS ARISING
        UNDER OR CONTEMPLATED BY THIS AGREEMENT FOR ANY INDIRECT, SPECIAL,
        CONSEQUENTIAL, PUNITIVE, EXEMPLARY OR INCIDENTAL DAMAGES OF WHATEVER
        KIND AND HOWEVER CAUSED (INCLUDING WITHOUT LIMITATION, DAMAGES FOR
        INTERRUPTION OF BUSINESS, PROCUREMENT OF SUBSTITUTE GOODS, LOSS OF
        PROFITS, OR THE LIKE) REGARDLESS OF THE FORM OF ACTION WHETHER IN
        CONTRACT, TORT (INCLUDING NEGLIGENCE), STRICT PRODUCT LIABILITY OR ANY
        OTHER LEGAL OR EQUITABLE THEORY EVEN IF SUCH PARTY HAS BEEN ADVISED OF
        THE POSSIBILITY OF SUCH DAMAGES.

                       ARTICLE 9 - TECHNOLOGY EXCLUSIVITY

9.1     USE AND SUBLICENSING IN CONNECTION WITH [CONFIDENTIAL TREATMENT
        REQUESTED]/*/ Commencing on the date on which any Result is first
        obtained for cash consideration and continuing throughout the Term ,
        EXACT shall not

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        [CONFIDENTIAL TREATMENT REQUESTED]/*/ without relying on the Licensed
        Process. However, if EXACT [CONFIDENTIAL TREATMENT REQUESTED]/*/ then
        the exclusive license granted pursuant to Section 2.1 shall be converted
        to a non-exclusive license. Similarly, commencing on the date on which
        any Result is first obtained for cash consideration and continuing
        throughout the Term, EXACT shall not [CONFIDENTIAL TREATMENT
        REQUESTED]/*/ without also requiring such third-party to become a
        Sublicensee hereunder and license the Licensed Process on terms that do
        not materially differ from the terms of this Agreement.

                        ARTICLE 10 - TERM AND TERMINATION

10.1    TERM. This Agreement shall commence on the Effective Date and shall
        remain effective for a period of [CONFIDENTIAL TREATMENT REQUESTED]/*/
        unless earlier terminated as provided by this Agreement (the "Term").
        This Agreement shall automatically be renewed for two successive periods
        of five years each (such renewal period also part of the "Term"), unless
        at least six months prior to the expiration of the then current Term or
        renewal Term, EXACT notifies APOGENT in writing of its desire to
        terminate this Agreement at the end of the then current Term or renewal
        Term. Thereafter, this Agreement shall automatically be renewed for a
        successive periods of one year each (each such renewal period also part
        of the "Term"), unless at least six months prior to the expiration of
        the then current renewal Term, one party notifies the other in writing
        of its desire to terminate this Agreement at the end of the then current
        Term.

10.2    TERMINATION FOR BREACH. Either Party may terminate this Agreement if the
        other Party materially breaches its obligations hereunder, and such
        breach is not cured within sixty (60) days after written noticed thereof
        to such other Party.

10.3    EFFECT OF TERMINATION. Upon early termination of this Agreement for any
        reason, EXACT shall notify each Sublicensee of the termination and
        APOGENT shall have the right, upon the Sublicensee's delivery to APOGENT
        no later than thirty days after the termination date of a written
        request for continuation of the Sublicensee's sublicense. Upon receipt
        of such request and receipt of proof from the Sublicensee, if reasonably
        requested by APOGENT, of the Sublicensee's ability to pay APOGENT
        royalties when due, Apogent will continue the Sublicensee's sublicense
        for the period equal to the shorter of the unexpired term of this
        Agreement or the unexpired term of the Sublicensee's sublicense from
        EXACT on condition that such Sublicensee remains in compliance with the
        terms and conditions of its sublicense agreement, and continues its
        payment obligations directly to APOGENT.

10.4    SURVIVAL. The following Articles shall survive the termination of this
        Agreement for any reason: Articles 1, 2.4, 5-8, 10.3, 10.4, 11 and 12.

                         ARTICLE 11 - DISPUTE RESOLUTION

11.1    DISPUTE RESOLUTION. If a dispute arises between the Parties relating to
        (i) the interpretation or performance of the Agreement; or (ii) the
        grounds for the

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        termination of the Agreement, the Parties agree to convene a Dispute
        Resolution Committee (the "Committee"), consisting of two EXACT
        representatives with decision-making authority and two APOGENT
        representatives with decision-making authority to attempt in good faith
        to negotiate a resolution of the dispute prior to pursuing other
        available remedies. Either Party may request the convening of a
        Committee by written notice to the other Party. A Committee shall
        convene for an initial meeting within forty-five (45) days of such
        written notice. If the Parties have not succeeded in negotiating a
        resolution of the dispute, within thirty (30) days after the initial
        meeting of the Committee, the dispute shall be submitted for binding
        arbitration under the then current Commercial Rules of the American
        Arbitration Association ("AAA").

11.2    Any arbitration under this Article 11 shall be held in Boston,
        Massachusetts. The Parties shall select three (3) arbitrators from a
        list of seven (7) arbitrators provided by the AAA. The Parties shall
        bear the costs of the arbitration equally unless the arbitrators,
        pursuant to their right, but not their obligation, require the
        non-prevailing Party to bear all or any unequal portion of the
        prevailing Party's costs. The arbitrators shall make decisions in
        accordance with applicable Federal and Massachusetts law and the factual
        evidence presented. The decision of the arbitrators shall be final and
        may be sued on or enforced by the Party in whose favor it runs in any
        court of competent jurisdiction at the option of the successful Party.
        The arbitrators will be instructed to prepare and deliver a written,
        reasoned opinion conferring their decision. The rights and obligations
        of the Parties to arbitrate any dispute relating to the interpretation
        or performance of this Agreement or the grounds for the termination
        thereof shall survive the expiration or termination of this Agreement
        for any reason. Nothing in this Agreement prevents either Party from
        seeking equitable relief at any time to prevent irreparable harm or for
        specific enforcement of the terms of this Agreement, except that no
        equitable relief shall be sought to prevent or avoid arbitration under
        the terms of this Agreement.

                           ARTICLE 12 - MISCELLANEOUS

12.1    NOTICES TO APOGENT. Unless otherwise specified in this Agreement,
        reports, notices and other communications from EXACT to APOGENT as
        provided hereunder must be sent to:

                Apogent Discoveries
                22 Friars Drive
                Hudson, New Hampshire 03051
                Attention: President

                WITH A COPY TO:

                Apogent Technologies Inc.
                Office of General Counsel
                30 Penhallow Street
                Portsmouth, New Hampshire 03801

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        or other individuals or addresses as APOGENT subsequently furnish by
        written notice to EXACT.

12.2    NOTICES TO EXACT. Unless otherwise specified in this Agreement, reports,
        notices and other communications from APOGENT to EXACT as provided
        hereunder must be sent to:


                EXACT Sciences Corporation
                63 Great Road
                Maynard, MA 01754

                With a copy to:
                Thomas C. Meyers
                Testa, Hurwitz & Thibeault, LLP
                125 High Street
                Boston, MA 02110


        or other individuals or addresses as EXACT subsequently furnish by
        written notice to APOGENT.

12.3    INDEPENDENT CONTRACTORS. The Parties agree that, in the performance of
        this Agreement, they are and shall be independent contractors. Nothing
        herein shall be construed to constitute a partnership or joint venture
        between the Parties nor shall any Party be construed as the agent of any
        other Party for any purpose whatsoever, and no Party shall bind or
        attempt to bind any other Party to any contract or the performance of
        any obligation, or represent to any third party that it has any right to
        enter into any binding obligation on the other Party's behalf.

12.4    SEVERABILITY. If any one or more of the provisions of this Agreement is
        held to be invalid, illegal or unenforceable, the validity, legality or
        enforceability of the remaining provisions of this Agreement will not in
        any way be affected or impaired thereby.

12.5    NON-ASSIGNABILITY. Neither this Agreement nor any part of the Agreement
        is assignable by either Party without the express written consent of the
        other Party, which shall not be unreasonably withheld, delayed or
        conditioned. Notwithstanding any of the foregoing, either Party may
        assign this Agreement and its rights and obligations hereunder, without
        the consent of the other Party, to an acquirer of all or substantially
        all of such Party's business or assets, whether by merger, sale,
        acquisition or other change of control transaction. This Agreement shall
        be binding upon and inure to the benefit of the Parties hereto and their
        respective successors and assigns.

12.6    ENTIRE AGREEMENT. This instrument contains the entire Agreement between
        the Parties. No verbal agreement, conversation or representation between
        any officers, agents, or employees of the Parties either before or after
        the execution of

                                     Page 11
<Page>

        this Agreement may affect or modify any of the terms or obligations
        herein contained.

12.7    MODIFICATIONS IN WRITING. No change, modification, extension, or waiver
        of this Agreement, or any of the provisions herein contained is valid
        unless made in writing and signed by a duly authorized representative of
        each Party.

12.8    GOVERNING LAW. The validity and interpretation of this Agreement and the
        legal relations of the Parties to it are governed by the laws of the
        Commonwealth of Massachusetts without regard to any choice of law
        principal that would dictate the application of the law of another
        jurisdiction. The Parties agree that any legal action arising out of or
        in connection with this Agreement shall be brought in the federal or
        state courts of Massachusetts, and the Parties irrevocably submit for
        all purposes to the jurisdiction of each such court.

12.9    CAPTIONS. The captions are provided for convenience and are not to be
        used in construing this Agreement.

12.10   COUNTERPARTS. This Agreement may be executed in counterparts, each of
        which shall be deemed an original and all of which when taken together
        shall be deemed but one instrument.

12.11   FORCE MAJEURE. If either Party fails to fulfill its obligations
        hereunder (other than an obligation for the payment of money), when such
        failure is due to an act of God, or other circumstances beyond its
        reasonable control, including but not limited to fire, flood, civil
        commotion, riot, war (declared and undeclared), acts of terrorism,
        revolution, or embargoes, then said failure shall be excused for the
        duration of such event and for such a time thereafter as is reasonable
        to enable the Parties to resume performance under this Agreement.


IN WITNESS WHEREOF, the Parties hereto have caused this agreement to be executed
in quadruplicate by their duly authorized representatives as of the date first
above written.

APOGENT DISCOVERIES                         EXACT SCIENCES CORPORATION


By:   /s/ R. Laurence Keene                 By:  /s/ Jeffrey T. Walsh
     -----------------------------------         -------------------------------

Name: R. Laurence Keene                     Name: Jeffrey T. Walsh
Title: Executive Vice President - Sales     Title: Vice President, Business
                                                     Development

Date:  November 26, 2002                    Date:  November 26, 2002

                                     Page 12
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                                    EXHIBIT 1

                  [CONFIDENTIAL TREATMENT REQUESTED]/*/ PATENTS

United States Patent Application Serial Number [CONFIDENTIAL TREATMENT
REQUESTED]/*/
United States Patent Application Serial Number [CONFIDENTIAL TREATMENT
REQUESTED]/*/
United States Patent No.[CONFIDENTIAL TREATMENT REQUESTED]/*/ United States
Patent Application Serial Number [CONFIDENTIAL TREATMENT REQUESTED]/*/
United States Patent No[CONFIDENTIAL TREATMENT REQUESTED]/*/
United States Patent Application Serial Number [CONFIDENTIAL TREATMENT
REQUESTED]/*/
United States Patent Application Serial Number [CONFIDENTIAL TREATMENT
REQUESTED]/*/

                                     Page 13
<Page>

                                    EXHIBIT 2

                                LICENSED PATENTS

UNITED STATES PATENTS:
- ---------------------
[CONFIDENTIAL TREATMENT REQUESTED]/*/

and all divisionals, continuations in part, or foreign counter parts thereto,
and any and all future patents owned or controlled Apogent, under which Company
would require a license to manufacture or use [CONFIDENTIAL TREATMENT
REQUESTED]/*/

FOREIGN PATENTS/APPLICATIONS:


[CONFIDENTIAL TREATMENT REQUESTED]/*/

                                     Page 14