<Page> EXHIBIT 3.5 CERTIFICATE OF AMENDMENT TO CERTIFICATE OF INCORPORATION OF MICROSCAN, INC. * * * * * * * * * * * PURSUANT TO SECTION 242(1) OF THE GENERAL CORPORATION LAW OF THE STATE OF DELAWARE * * * * * * * * * * * Scott T. Garrett and Colin R. Silvester, being the duly elected and acting President and Treasurer, respectively of MicroScan Inc., a corporation organized and existing under and by virtue of the laws of the State of Delaware, do hereby certify as follows: 1. The name of the corporation (hereinafter called the "Corporation") is MicroScan, Inc. 2. The Certificate of Incorporation which was filed by the Secretary of State of Delaware on November 23, 1994 (the "Certificate of Incorporation") is hereby amended, effective March 1, 1995 as follows: ARTICLE ONE The name of the corporation is DADE MICROSCAN INC. IN WITNESS WHEREOF, the undersigned do hereby certify under penalties of perjury that this Certificate of Amendment to the Certificate of Incorporation is the act and deed of the undersigned and the facts stated herein are true and accordingly have hereunto set their hands this 1st day of March, 1995 DADE MICROSCAN INC. a Delaware Corporation By: /s/ Scott T. Garrett ---------------------------- Scott T. Garrett, President By: /s/ Colin R. Silvester ---------------------------- Colin R. Silvester, Treasurer ATTEST: /s/ Louise S. Pearson - ----------------------------- Louise S. Pearson, Assistant Secretary <Page> CERTIFICATE OF INCORPORATION OF MIRCOSCAN, INC. ARTICLE ONE The name of the corporation is MicroScan, Inc. ARTICLE TWO The address of the corporation's registered office in the State of Delaware is 32 Loookerman Square, Suite L-100, in the City of Dover, County of Kent 19904. The name of its registered agent at such address is The Prentice-Hall Corporation System, Inc. ARTICLE THREE The nature of the business or purposes to be conducted or promoted is to engage in any lawful act or activity for which corporations may be organized under the General Corporation Law of the State of Delaware. ARTICLE FOUR The total number of shares of stock which the corporation has authority to issue is one thousand (1,000) shares of Common Stock, par value one cent ($0.01) per share. ARTICLE FIVE The name and mailing address of the sole incorporator are as follows: <Page> undersigned and the facts stated herein are true and accordingly have hereunto set their hands this 7th day of December, 1994. MICROSCAN, INC., a Delaware corporation By: /s/ Stephen G. Pagliuca ----------------------------------- Stephen G. Pagliuca President ATTEST: /s/ Adam Kirsch - ---------------------------------- Adam Kirsch Assistant Secretary - 2 - <Page> NAME MAILING ADDRESS ---- --------------- Thaddine G. Gomez 200 East Randolph Drive Suite 5700 Chicago, Illinois 60601 ARTICLE SIX The corporation is to have perpetual existence. ARTICLE SEVEN In furtherance and not in limitation of the powers conferred by statute, the board of directors of the corporation is expressly authorized to make, alter or repeal the by-laws of the corporation. ARTICLE EIGHT Meetings of stockholders may be held within or without the State of Delaware, as the by-laws of the corporation may provide. The books of the corporation may be kept outside the State of Delaware at such place or places as may be designated from time to time by the board of directors or in the by-laws of the corporation. Election of directors need not be by written ballot unless the by-laws of the corporation so provide. ARTICLE NINE To the fullest extent permitted by the General Corporation Law of the State of Delaware as the same exists or may hereafter be amended, a director of this corporation shall not be liable to the corporation or its stockholders for monetary damages for a breach of fiduciary duty as a director. Any repeal or modification of this ARTICLE NINE shall not adversely affect any right or protection of a director of the corporation existing at the time of such repeal or modification. -2- <Page> ARTICLE TEN The corporation expressly elects not to be governed by Section 203 of the General Corporation Law of the State of Delaware. ARTICLE ELEVEN The corporation reserves the right to amend, alter, change or repeal any provision contained in this certificate of incorporation in the manner now or hereafter prescribed herein and by the laws of the State of Delaware, and all rights conferred upon stockholders herein are granted subject to this reservation. I, THE UNDERSIGNED, being the sole incorporator hereinbefore named, for the purpose of forming a corporation pursuant to the General Corporation Law of the State of Delaware, do make this certificate, hereby declaring and certifying that this is my act and deed and the facts stated herein are true, and accordingly have hereunto set my hand on the 23rd day of November, 1994. /s/ Thaddine G. Gomez ------------------------------------ Thaddine G. Gomez Sole Incorporator -3-