<Page> Exhibit 12.1 THE JEAN COUTU GROUP (PJC) INC. COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES (DOLLARS IN THOUSAND, EXCEPT FOR RATIO OF EARNINGS TO FIXED CHARGES) <Table> <Caption> 3 MONTHS 13 WEEKS PERIOD ENDED PERIOD ENDED ---------------------------- AUGUST 31 AUGUST 28 2000 2001 2002 2003 2004 2003 2004 --------------------------------------------------------------------------------------- CANADIAN GAAP Fixed charges Interest expense 10,225 9,259 10,900 17,857 14,535 4,107 18,027 Portion of rental expense representing the interest factor 12,422 9,502 10,351 11,744 12,468 4,154 10,201 ----------------------------------------------------------------------------------- 22,647 18,761 21,251 29,601 27,003 8,261 28,228 ----------------------------------------------------------------------------------- Earnings Income before income taxes 90,608 107,176 130,640 150,880 193,754 46,078 18,101 Fixed charges 22,647 18,761 21,251 29,601 27,003 8,261 28,228 ----------------------------------------------------------------------------------- 113,255 125,937 151,891 180,481 220,757 54,339 46,329 ----------------------------------------------------------------------------------- Ratio of earnings to fixed charges 5.0 6.7 7.1 6.1 8.2 6.6 1.6 =================================================================================== U.S. GAAP Fixed charges Interest expense 10,225 9,259 10,900 17,857 14,535 4,107 18,027 Portion of rental expense representing the interest factor 12,422 9,502 10,351 11,744 12,468 4,154 10,201 ----------------------------------------------------------------------------------- 22,647 18,761 21,251 29,601 27,003 8,261 28,228 ----------------------------------------------------------------------------------- Earnings Income before income taxes 89,525 106,382 129,474 147,122 191,625 45,587 18,224 Fixed charges 22,647 18,761 21,251 29,601 27,003 8,261 28,228 ----------------------------------------------------------------------------------- 112,172 125,143 150,725 176,723 218,628 53,848 46,452 ----------------------------------------------------------------------------------- Ratio of earnings to fixed charges 5.0 6.7 7.1 6.0 8.1 6.5 1.6 =================================================================================== </Table> <Page> THE JEAN COUTU GROUP (PJC) INC. COMPUTATION OF TOTAL INDEBTEDNESS TO ADJUSTED EBITDA (DOLLARS IN THOUSAND, EXCEPT FOR RATIO OF TOTAL INDEBTEDNESS TO ADJUSTED EBITDA) <Table> <Caption> 2000 2001 2002 2003 2004 ------------------------------------------------------------- CANADIAN GAAP Total indebtedness 143,735 111,476 263,456 260,755 207,175 Adjusted EBITDA 131,936 147,585 171,511 205,675 249,722 ------------------------------------------------------------- Ratio of total indebtedness to adjusted EBITDA 1.1 0.8 1.5 1.3 0.8 -------------------------------------------------------------- U.S. GAAP Total indebtedness 143,735 111,476 263,456 260,755 207,175 Adjusted EBITDA 132,011 147,788 171,613 203,632 249,722 ------------------------------------------------------------- Ratio of total indebtedness to adjusted EBITDA 1.1 0.8 1.5 1.3 0.8 ------------------------------------------------------------- </Table> <Page> THE JEAN COUTU GROUP (PJC) INC. COMPUTATION OF INTEREST COVERAGE (ADJUSTED EBITDA TO INTEREST) (DOLLARS IN THOUSAND, EXCEPT FOR RATIO OF INTEREST COVERAGE (ADJUSTED EBITDA TO INTEREST) <Table> <Caption> 2000 2001 2002 2003 2004 ------------------------------------------------------------------ CANADIAN GAAP Adjusted EBITDA 131,936 147,585 171,511 205,675 249,722 Interest expense 10,226 9,259 10,900 17,858 14,535 ---------------------------------------------------------------- Ratio of interest coverage (adjusted EBITDA to interest) 12.9 15.9 15.7 11.5 17.2 ---------------------------------------------------------------- U.S. GAAP Adjusted EBITDA 132,011 147,788 171,613 203,632 249,722 Interest expense 10,226 9,259 10,900 17,858 14,535 ---------------------------------------------------------------- Ratio of interest coverage (adjusted EBITDA to interest) 12.9 16.0 15.7 11.4 17.2 ---------------------------------------------------------------- </Table>