<Page>

                                                                    Exhibit 12.1

THE JEAN COUTU GROUP (PJC) INC.
COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES
(DOLLARS IN THOUSAND, EXCEPT FOR RATIO OF EARNINGS TO FIXED CHARGES)

<Table>
<Caption>
                                                                                                     3 MONTHS       13 WEEKS
                                                                                                   PERIOD ENDED    PERIOD ENDED
                                                                                                   ----------------------------
                                                                                                     AUGUST 31      AUGUST 28
                                          2000        2001        2002        2003        2004         2003           2004
                                        ---------------------------------------------------------------------------------------

                                                                                                
CANADIAN GAAP
Fixed charges
   Interest expense                      10,225       9,259      10,900      17,857      14,535        4,107         18,027
   Portion of rental
      expense representing
      the interest factor                12,422       9,502      10,351      11,744      12,468        4,154         10,201
                                        -----------------------------------------------------------------------------------
                                         22,647      18,761      21,251      29,601      27,003        8,261         28,228
                                        -----------------------------------------------------------------------------------

Earnings
   Income before income taxes            90,608     107,176     130,640     150,880     193,754       46,078         18,101
   Fixed charges                         22,647      18,761      21,251      29,601      27,003        8,261         28,228
                                        -----------------------------------------------------------------------------------
                                        113,255     125,937     151,891     180,481     220,757       54,339         46,329
                                        -----------------------------------------------------------------------------------

Ratio of earnings to fixed charges          5.0         6.7         7.1         6.1         8.2          6.6            1.6
                                        ===================================================================================


U.S. GAAP
Fixed charges
   Interest expense                      10,225       9,259      10,900      17,857      14,535        4,107         18,027
   Portion of rental
      expense representing
      the interest factor                12,422       9,502      10,351      11,744      12,468        4,154         10,201
                                        -----------------------------------------------------------------------------------
                                         22,647      18,761      21,251      29,601      27,003        8,261         28,228
                                        -----------------------------------------------------------------------------------

Earnings
   Income before income taxes            89,525     106,382     129,474     147,122     191,625       45,587         18,224
   Fixed charges                         22,647      18,761      21,251      29,601      27,003        8,261         28,228
                                        -----------------------------------------------------------------------------------
                                        112,172     125,143     150,725     176,723     218,628       53,848         46,452
                                        -----------------------------------------------------------------------------------

Ratio of earnings to fixed charges          5.0         6.7         7.1         6.0         8.1          6.5            1.6
                                        ===================================================================================
</Table>

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THE JEAN COUTU GROUP (PJC) INC.
COMPUTATION OF TOTAL INDEBTEDNESS TO ADJUSTED EBITDA
(DOLLARS IN THOUSAND, EXCEPT FOR RATIO OF TOTAL INDEBTEDNESS TO ADJUSTED EBITDA)

<Table>
<Caption>




                                   2000         2001         2002         2003         2004
                                  -------------------------------------------------------------

                                                                       
CANADIAN GAAP

Total indebtedness                143,735      111,476      263,456      260,755      207,175
Adjusted EBITDA                   131,936      147,585      171,511      205,675      249,722
                                  -------------------------------------------------------------

Ratio of total indebtedness
   to adjusted EBITDA                 1.1          0.8          1.5          1.3          0.8
                                  --------------------------------------------------------------


U.S. GAAP

Total indebtedness                143,735      111,476      263,456      260,755      207,175
Adjusted EBITDA                   132,011      147,788      171,613      203,632      249,722
                                  -------------------------------------------------------------

Ratio of total indebtedness
   to adjusted EBITDA                 1.1          0.8          1.5          1.3          0.8
                                  -------------------------------------------------------------
</Table>

<Page>

THE JEAN COUTU GROUP (PJC) INC.
COMPUTATION OF INTEREST COVERAGE (ADJUSTED EBITDA TO INTEREST)
(DOLLARS IN THOUSAND, EXCEPT FOR RATIO OF INTEREST COVERAGE (ADJUSTED EBITDA TO
INTEREST)

<Table>
<Caption>
                                     2000          2001          2002          2003          2004
                                  ------------------------------------------------------------------

                                                                             
CANADIAN GAAP

Adjusted EBITDA                     131,936       147,585       171,511       205,675       249,722
Interest expense                     10,226         9,259        10,900        17,858        14,535
                                    ----------------------------------------------------------------

Ratio of interest coverage
   (adjusted EBITDA to interest)       12.9          15.9          15.7          11.5          17.2
                                    ----------------------------------------------------------------


U.S. GAAP

Adjusted EBITDA                     132,011       147,788       171,613       203,632       249,722
Interest expense                     10,226         9,259        10,900        17,858        14,535
                                    ----------------------------------------------------------------

Ratio of interest coverage
   (adjusted EBITDA to interest)       12.9          16.0          15.7          11.4          17.2
                                    ----------------------------------------------------------------
</Table>