<Page> Exhibit 21.1 LIST OF SUBSIDIARIES The Jean Coutu Group (PJC) Inc. has the following subsidiaries: 3090671 Nova Scotia Company, a Nova Scotia Corporation. 3090672 Nova Scotia Company, a Nova Scotia Corporation. Paterson's Pharmacies Ltd., an Ontario Corporation. RX Information Centre Ltd., a Quebec Corporation. Services Securivol Inc., a Quebec Corporation. The Jean Coutu Group (PJC) USA, Inc., a Delaware Corporation. The Jean Coutu Group (PJC) USA Inc. has the following subsidiaries: Brooks Pharmacy, Inc., a Delaware Corporation. Maxi Drug, Inc., a Delaware Corporation. MC Woonsocket, Inc., a Rhode Island Corporation. P.J.C Distribution, Inc., a Delaware Corporation. P.J.C. Realty Co., Inc., a Delaware Corporation. PJC Lease Holdings, Inc., a Delaware Corporation. PJC of Cranston, Inc., a Rhode Island Corporation. PJC of East Providence, Inc., a Rhode Island Corporation. PJC of Massachusetts, Inc., a Massachusetts Corporation. PJC of Vermont, Inc., a Vermont Corporation. PJC of West Warwick, Inc., a Rhode Island Corporation. PJC Special Realty Holdings, Inc., a Delaware Corporation. PJC Realty N.E. LLC, a Delaware Corporation. JCG Holdings (USA) Inc. has the following subsidiaries: Eckerd Corporation, a Delaware Corporation. Genovese Drug Stores, Inc., a Delaware Corporation. Thrift Drug Inc., a Delaware Corporation. Thrift Drug Services, Inc., a Delaware Corporation. Jean Coutu Group Holdings (USA) LLC has the following subsidiaries: JCG Holdings (USA) LLC, a Delaware Corporation. Eckerd Corporation has the following subsidiaries: Eckerd Fleet, Inc., a Florida Corporation. EDC Licensing, Inc., a Delaware Corporation. MC Woonsocket has the following subsidiaries: PJC of Rhode Island, Inc., a Rhode Island Corporation. Maxi Drug, Inc. has the following subsidiaries: Maxi Drug North, Inc., a Delaware Corporation. Maxi Green Inc., a Vermont Corporation. <Page> Maxi Drug North, Inc. and Maxi Drug, Inc. are the limited and general partners, respectively, of the following subsidiary: Maxi Drug South, L.P., a Delaware Corporation. PJC Realty Co., Inc. has the following subsidiaries: PJC Realty MA, Inc., a Massachusetts Corporation. PJC Special Realty Holdings, Inc. has the following subsidiaries PJC Arlington Realty LLC, a Delaware Corporation. PJC Dorchester Realty LLC, a Delaware Corporation. PJC Essex Realty LLC, a Delaware Corporation. PJC Haverhill Realty LLC, a Delaware Corporation. PJC Hyde Park Realty LLC, a Delaware Corporation. PJC Manchester Realty LLC, a Delaware Corporation. PJC Mansfield Realty LLC, a Delaware Corporation. PJC New London Realty LLC, a Delaware Corporation. PJC Norwich Realty LLC, a Delaware Corporation. PJC Peterborough Realty LLC, a Delaware Corporation. PJC Providence Realty LLC, a Delaware Corporation. PJC Revere Realty LLC, a Delaware Corporation. Thrift Drug Inc. has the following subsidiaries: EDC Drug Stores, Inc., a North Carolina Corporation. The following registrants have no subsidiaries: 3090671 Nova Scotia Company, a Nova Scotia Corporation. 3090672 Nova Scotia Company, a Nova Scotia Corporation. Brooks Pharmacy, Inc., a Delaware Corporation. Eckerd Fleet, Inc., a Florida Corporation. EDC Drug Stores, Inc., a North Carolina Corporation. EDC Licensing, Inc., a Delaware Corporation. Genovese Drug Stores, Inc., a Delaware Corporation. Maxi Drug South, L.P., a Delaware Corporation. Maxi Green Inc., a Vermont Corporation. P.J.C. Distribution, Inc., a Delaware Corporation. Paterson's Pharmacies Ltd., an Ontario Corporation. PJC Arlington Realty LLC, a Delaware Corporation. PJC Dorchester Realty LLC, a Delaware Corporation. PJC Essex Realty LLC, a Delaware Corporation. PJC Haverhill Realty LLC, a Delaware Corporation. PJC Hyde Park Realty LLC, a Delaware Corporation. PJC Lease Holdings, Inc., a Delaware Corporation. PJC Manchester Realty LLC, a Delaware Corporation. PJC Mansfield Realty LLC, a Delaware Corporation. PJC New London Realty LLC, a Delaware Corporation. PJC Norwich Realty LLC, a Delaware Corporation. <Page> PJC of Cranston, Inc., a Rhode Island Corporation. PJC of East Providence, Inc., a Rhode Island Corporation. PJC of Massachusetts, Inc., a Massachusetts Corporation. PJC of Rhode Island, Inc., a Rhode Island Corporation. PJC of Vermont, Inc., a Vermont Corporation. PJC of West Warwick, Inc., a Rhode Island Corporation. PJC Peterborough Realty LLC, a Delaware Corporation. PJC Providence Realty LLC, a Delaware Corporation. PJC Realty MA, Inc., a Massachusetts Corporation. PJC Realty N.E. LLC, a Delaware Corporation. PJC Revere Realty LLC, a Delaware Corporation. RX Information Centre Ltd., a Quebec Corporation. Services Securivol Inc., a Quebec Corporation. Thrift Drug Services, Inc., a Delaware Corporation.