EXHIBIT 11.1---STATEMENT RE: COMPUTATION OF PER SHARE EARNINGS (UNAUDITED) GALAGEN INC. (A DEVELOPMENT STAGE COMPANY) Period from November 17, For the Three months Ended For the Nine months Ended 1987 (inception) to ----------------------------- ---------------------------- ------------------- September 30, September 30, September 30, September 30, September 30, 1997 1996 1997 1996 1997 ---- ---- ---- ---- ---- Primary Loss Per Share: Average shares outstanding 7,186,180 7,134,136 7,173,078 6,450,999 2,087,995 SAB No. 83 shares - for stock options granted at exercise prices less than the initial public offering price during the 12 months preceding the initial public offering using the treasury method - - - - 109,163 --------------------------------------------------------------------------------- Total 7,186,180 7,134,136 7,173,078 6,450,999 2,197,157 --------------------------------------------------------------------------------- --------------------------------------------------------------------------------- Net loss $(1,282,943) $(1,955,731) $(4,316,437) $(12,661,123) $(51,500,357) --------------------------------------------------------------------------------- --------------------------------------------------------------------------------- Net loss per share $(0.18) $(0.27) $(0.60) $(1.96) $(23.44) --------------------------------------------------------------------------------- --------------------------------------------------------------------------------- Fully Diluted Loss Per Share: Average shares outstanding 7,186,180 7,134,136 7,173,078 6,450,999 2,087,995 SAB No. 83 shares - for stock options granted at exercise prices less than the initial public offering price during the 12 months preceding the initial public offering using the treasury method - - - - 109,163 Assumed conversion of all series of convertible preferred stock - - - - 611,383 --------------------------------------------------------------------------------- Total 7,186,180 7,134,136 7,173,078 6,450,999 2,808,541 --------------------------------------------------------------------------------- --------------------------------------------------------------------------------- Net loss $(1,282,943) $(1,955,731) $(4,316,437) $(12,661,123) $(51,500,357) --------------------------------------------------------------------------------- --------------------------------------------------------------------------------- Net loss per share $(0.18) $(0.27) $(0.60) $(1.96) $(18.34) --------------------------------------------------------------------------------- ---------------------------------------------------------------------------------