Exhibit (10.2)

                                   EXHIBIT A-1
                         to Securities Purchase Agreement

                    VOID AFTER 5:00 P.M. BELTSVILLE, MARYLAND
                             TIME ON DECEMBER 12, 2000

THE SECURITIES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER 
THE SECURITIES ACT OF 1933, AS AMENDED, OR THE SECURITIES LAWS OF ANY STATE 
OF THE UNITED STATES.  THE SECURITIES REPRESENTED HEREBY MAY NOT BE OFFERED 
OR SOLD OR OTHERWISE TRANSFERRED IN THE ABSENCE OF AN EFFECTIVE REGISTRATION 
STATEMENT FOR THE SECURITIES UNDER APPLICABLE SECURITIES LAWS OR UNLESS 
OFFERED, SOLD OR TRANSFERRED PURSUANT TO AN AVAILABLE EXEMPTION FROM THE 
REGISTRATION REQUIRMETNS OF THOSE LAWS.

                                           Right to Purchase 375,000 Shares of
                                       Common Stock, par value $.005 per share
Date:  December 12, 1997


                             BIOSPHERICS INCORPORATED
                              STOCK PURCHASE WARRANT

     THIS CERTIFIES THAT, for value received, RGC International Investors, 
LDC, or its registered assigns, is entitled to purchase from Biospherics 
Incorporated, a Delaware corporation (the "Company"), at any time or from 
time to time during the period specified in Section 2 hereof, 375,000 fully 
paid and nonassessable shares of the Company's common stock, par value $.005 
per share (the "Common Stock"), at an exercise price of $4.00 per share (the 
"Exercise Price").  This Warrant is being issued pursuant to that certain 
Securities Purchase Agreement dated December 12, 1997 between the Company and 
the signatories thereto (the "Securities Purchase Agreement").  The number of 
shares of Common Stock purchaseable hereunder (the "Warrant Shares") and the 
Exercise Price are subject to adjustment as provided in Section 4 hereof. The 
term "Warrants" means this Warrant and the other warrants of the Company 
issued pursuant to the terms of the Securities Purchase Agreement.

     The term "Closing Price" means, for any security as of any date, the 
last reported sale price of such security on the principal securities 
exchange or trading market where such security is listed or traded as 
reported by Bloomberg Financial Markets or a comparable reporting service of 
national reputation selected by the Company and reasonably acceptable to the 
holder hereof (the "Holder") if Bloomberg Financial Markets is not then 
reporting sale prices of such security (collectively, "Bloomberg"), or if the 
foregoing does not apply, the last reported sale price of such security in 
the over-the-counter market on the electronic bulletin board of such security 
as reported by Bloomberg, or, if no sale price is reported for such security 
by Bloomberg, the average of the bid prices of any market makers for such 
security as reported in the "pink sheets" by the National Quotation Bureau, 
Inc.  If the Closing Price cannot be calculated for such 

                                       1



security on such date on any of the foregoing bases, the Closing Price of 
such security on such date shall be the fair market value as reasonably 
determined by an investment bank firm selected by the Company and reasonably 
acceptable to the Holder with the costs of such appraisal to be borne by the 
Company.

     This Warrant is subject to the following terms, provisions, and 
conditions:

     1.   Mechanics of Exercise.  Subject to the provisions hereof, 
including, without limitation, the limitations contained in Section 7(f) 
hereof, this Warrant may be exercised as follows:

     (a)  Manner of Exercise.  This Warrant may be exercised by the Holder, 
in whole or in part, by the surrender of this Warrant (or evidence of loss, 
theft, destruction or mutilation thereof in accordance with Section 11(e) 
hereof), together with a completed exercise agreement in the Form of Exercise 
Agreement attached hereto as Exhibit 1 (the "Exercise Agreement"), to the 
Company at the Company's principal executive offices (or such other office or 
agency of the Company as it may designate by notice to the Holder), and upon 
(i) payment to the Company in cash, by certified or official bank check or by 
wire transfer for the account of the Company, of the Exercise Price for the 
Warrant Shares specified in the Exercise Agreement or (ii) if the resale of 
the Warrant Shares by the holder is not then registered pursuant to an 
effective registration statement under the Securities Act, delivery to the 
Company of a written notice of an election to effect a Cashless Exercise (as 
defined in Section 11(c) below) for the Warrant Shares specified in the 
Exercise Agreement.  The Warrant Shares so purchased shall be deemed to be 
issued to the Holder or Holder's designees, as the record owner of such 
shares, as of the date on which this Warrant shall have been surrendered, the 
contemplated Exercise Agreement shall have been delivered, and payment (or 
notice of an election to effect a Cashless Exercise) shall have been made for 
such shares as set forth above.

     (b)  Issuance of Certificates.  Subject to Section 1(c), certificates 
for the Warrant Shares so purchased, representing the aggregate number of 
shares specified in the Exercise Agreement, shall be delivered to the Holder 
within a reasonable time, not exceeding three (3) business days, after this 
Warrant shall have been so exercised (the "Delivery Period").  The 
certificates so delivered shall be in such denominations as may be requested 
by the Holder and shall be registered in the name of Holder or such other 
name as shall be designated by such Holder.  If this Warrant shall have been 
exercised only in part, then, unless this Warrant has expired, the Company 
shall, at its expense, at the time of delivery of such certificates, deliver 
to the Holder a new Warrant representing the number of shares with respect to 
which this Warrant shall not then have been exercised.

     (c)  Exercise Disputes.  In the case of any dispute with respect to an 
exercise, the Company shall promptly issue such number of shares of Common 
Stock as are not disputed in accordance with this Section.  If such dispute 
involves the calculation of the Exercise Price, the Company shall submit the 
disputed calculations to a "Big Six" independent accounting firm (selected by 
the Company) via facsimile within three (3) business days of receipt of the 
Exercise Agreement.  The accounting firm shall review the calculations and 
notify the Company and the converting Holder of the results no later than two 
(2) business days from the date it receives the disputed calculations.  The 
accounting firm's calculation shall be deemed conclusive, absent              

                                       2 


manifest error.  The Company shall then issue the appropriate number of 
shares of Common Stock in accordance with this Section.

     (d)  Fractional Shares.  No fractional shares of Common Stock are to be 
issued upon the exercise of this Warrant, but the Company shall pay a cash 
adjustment in respect of any fractional share which would otherwise be 
issuable in an amount equal to the same fraction of the Exercise Price of a 
share of Common Stock (as determined for exercise of this Warrant into whole 
shares of Common Stock); provided that in the event that sufficient funds are 
not legally available for the payment of such cash adjustment any fractional 
shares of Common Stock shall be rounded up to the next whole number.

     (e)  Buy-In.  If (i) the Company fails for any reason to deliver during 
the Delivery Period shares of Common Stock to Holder upon an exercise of this 
Warrant and (ii) after the applicable Delivery Period with respect to such an 
exercise, Holder purchases (in an open market transaction or otherwise) 
shares of Common Stock to make delivery upon a sale by Holder of the shares 
of Common Stock (the "Sold Shares") which Holder was entitled to receive upon 
such exercise (a "Buy-in"), the Company shall pay Holder (in addition to any 
other remedies available to Holder) the amount by which (x) Holder's total 
purchase price (including brokerage commission, if any) for the shares of 
Common Stock so purchased exceeds (y) the lesser of (A) the Exercise Price or 
(B) the net proceeds received by Holder from the sale of the Sold Shares. 
Holder shall provide the Company written notification indicating any amounts 
payable to Holder pursuant to this subsection.

     2.   Period of Exercise.  This Warrant is exercisable at any time or 
from time to time on or after the date hereof and before 5:00 P.M., 
Beltsville, Maryland, time on the third (3rd) anniversary of the date hereof 
(the "Exercise Period").

     3.   Certain Agreements of the Company.  The Company hereby covenants 
and agrees as follows:

     (a)  Shares to be Fully Paid.  All Warrant Shares will, upon issuance in 
accordance with the terms of this Warrant, be validly issued, fully paid, and 
nonassessable and free from all taxes, liens, claims and encumbrances.

     (b)  Reservation of Shares.  During the Exercise Period, the Company 
shall at all times have authorized, and reserved for the purpose of issuance 
upon exercise of this Warrant, a sufficient number of shares of Common Stock 
to provide for the exercise of this Warrant.

     (c)  Listing.  The Company shall promptly secure the listing of the 
shares of Common Stock issuable upon exercise of this Warrant upon the NASDAQ 
National Market ("NASDAQ") as required by Section 4.9 of the Securities 
Purchase Agreement and upon each national securities exchange or automated 
quotation system, if any, upon which shares of Common Stock are then listed 
or become listed and shall maintain, so long as any other shares of Common 
Stock shall be so listed, such listing of all shares of Common Stock from 
time to time issuable upon the exercise of this Warrant; and the Company 
shall so list on each national securities exchange or automated quotation 
system, as the case may be, and shall maintain such listing of any other 
shares of capital stock of the Company issuable upon the exercise of this 
Warrant so long as any 

                                       3


shares of the same class shall be listed on such national securities exchange 
or automated quotations system.

     (d)  Certain Actions Prohibited.  The Company will not, by amendment of 
its charter or through any reorganization, transfer of assets, consolidation, 
merger, dissolution, issue or sale of securities, or any other voluntary 
action, avoid or seek to avoid the observance or performance of any of the 
terms to be observed or performed by it hereunder, but will at all times in 
good faith assist in carrying out of all the provisions of this Warrant and 
in the taking of all such actions as may reasonably by requested by the 
Holder of this Warrant in order to protect the exercise privilege of the 
Holder of this Warrant, consistent with the tenor and purpose of this 
Warrant.  Without limiting the generality of the foregoing, the Company (i) 
will not increase the par value of any shares of Common Stock receivable upon 
the exercise of this Warrant above the Exercise Price then in effect, and 
(ii) will take all such actions as may be necessary or appropriate in order 
that the Company may validly and legally issue fully paid and nonassessable 
shares of Common Stock upon the exercise of this Warrant.

     (e)  Successors and Assigns.  This Warrant will be binding upon any 
entity succeeding to the Company by merger, consolidation, or acquisition of 
all or substantially all of the Company's assets.

     4.   Antidilution Provisions.  During the Exercise Period, the Exercise 
Price and the number of Warrant Shares shall be subject to adjustment from 
time to time as provided in this Section 4.  In the event that any adjustment 
of the Exercise Price as required herein results in a fraction of a cent, 
such Exercise Price shall be rounded up or down to the nearest cent.

     (a)  Adjustment of Exercise Price and Number of Shares upon Issuance of 
Common Stock.  Except as otherwise provided in Section 4(c) and 4(e) hereof, 
if and whenever after the initial issuance of this Warrant, the Company 
issues or sells, or in accordance with Section 4(b) hereof is deemed to have 
issued or sold, any shares of Common Stock for no consideration or for a 
consideration per share less than the Market Price (as herein defined) on the 
date of issuance (a "Dilutive Issuance"), then effective immediately upon the 
Dilutive Issuance, the Exercise Price will be adjusted in accordance with the 
following formula:

          E' = E x  O + P/M
                    -------
                    CSDO

          where

          E'   =    the adjusted Exercise Price;
          E    =    the then current Exercise Price;
          M    =    the then current Market Price;
          O    =    the number of shares of Common Stock outstanding immediately
                    prior to the Dilutive Issuance;
          P    =    the aggregate consideration, calculated as set forth in 
                    Section 4(b) hereof, received by the Company upon such 
                    Dilutive Issuance; and
          CSDO =    the total number of shares of Common Stock Deemed 
                    Outstanding (as herein defined) immediately after the 
                    Dilutive Issuance.

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     (b)  Effect of Exercise Price of Certain Events. For purposes of 
determining the adjusted Exercise Price under Section 4(a) hereof, the following
will be applicable:

          (i)    Issuance of Rights or Options.  If the Company in any manner 
issues or grants any warrants, rights or options, whether or not immediately 
exercisable, to subscribe for or to purchase Common Stock or other securities 
exercisable, convertible into or exchangeable for Common Stock ("Convertible 
Securities"), but not to include the grant or exercise of any stock or 
options which may hereafter be granted or exercised under any employee or 
Director benefit plan of the Company now existing or to be implemented in the 
future, so long as the issuance of such stock or options is approved by 
majority of the non-employee members of the Board  of Directors of the 
Company or a majority of the members of a committee of non-employee directors 
established for such purpose (such warrants, rights and options to purchase 
Common Stock or Convertible Securities are hereinafter referred to as 
"Options"), and the price per share for which Common Stock is issuable upon 
the exercise of such Options is less than the Market Price on the date of 
issuance ("Below Market Options"),then the maximum total number of shares of 
Common Stock issuable upon the exercise of all such Below Market Options 
(assuming full exercise, conversion or exchange of Convertible Securities, if 
applicable) will, as of the date of the issuance or grant of such Below 
Market Options, be deemed to be outstanding and to have been issued and sold 
by the Company for such price per share.  For purposes of the preceding 
sentence, the price per share for which Common Stock is issuable upon the 
exercise of such Below Market Options is determined by dividing (i) the total 
amount, if any, received or receivable by the Company as consideration for 
the issuance or granting of such Below Market Options, plus the minimum 
aggregate amount of additional consideration, if any, payable to the Company 
upon the exercise of all such Below Market Options, plus, in the case of 
Convertible Securities issuable upon the exercise of such Below Market 
Options, the minimum aggregate amount of additional consideration payable 
upon the exercise, conversion or exchange thereof at the time such 
Convertible Securities first become exercisable, convertible or exchangeable, 
by (ii) the maximum total number of shares of Common Stock issuable upon the 
exercise of all such Below Market Options (assuming full conversion of 
Convertible Securities, if applicable). No further adjustment to the Exercise 
Price will be made upon the actual issuance of such Common Stock upon the 
exercise of such Below Market Options or upon the exercise, conversion or 
exchange of Convertible Securities issuable upon exercise of such Below 
Market Options.

          (ii)   Issuance of Convertible Securities.

                 (A)  If the Company in any manner issues or sells any 
Convertible Securities, whether or not immediately convertible (other than 
where the same are issuable upon the exercise of Options) and the price per 
share for which Common Stock is issuable upon such exercise, conversion or 
exchange (as determined pursuant to Section 4(b)(ii)(B) if applicable) is 
less than the Market Price on the date of issuance, then the maximum total 
number of shares of Common Stock issuable upon the exercise, conversion or 
exchange of all such Convertible Securities will, as of the date of issuance 
of such Convertible Securities, be deemed to be outstanding and to have been 
issued and sold by the Company for such price per share.  For the purposes of 
the preceding sentence, the price per share for which Common Stock is 
issuable upon such exercise, conversion or exchange is determined by dividing 
(i) the total amount, if any, received or receivable by the Company as 
consideration for the issuance or sale of all such Convertible Securities, 
plus the minimum aggregate amount of additional consideration, if any,

                                       5


payable to the Company upon the exercise, conversion or exchange thereof at 
the time such Convertible Securities first become exercisable, onvertible or 
exchangeable, by (ii) the maximum total number of share of Common Stock 
issuable upon the exercise, conversion or exchange of all such Convertible 
Securities.  No further adjustment to the Exercise Price will be made upon 
the actual issuances of such Common Stock upon exercise, conversion or 
exchange of such Convertible Securities.

                 (B)  If the Company in any manner issues or sells any 
Convertible Securities with a fluctuating conversion or exercise price or 
exchange ratio (a "Variable Rate Convertible Security"), then the price per 
share for which Common Stock is issuable upon such exercise, conversion or 
exchange for purposes of the calculation contemplated by Section 4(b)(ii)(A) 
shall be deemed to be the lowest price per share which would be applicable 
assuming that (1) all holding period and other conditions to any discounts 
contained in such Convertible Security have been satisfied, and (2) the 
Market Price on the date of issuance of such Convertible Security was 80% of 
the Market Price on such date (the "Assumed Variable Market Price").

          (iii)  Change in Option Price or Conversion Rate.  Except for the 
grant or exercise of any stock or options which may hereafter be granted or 
exercised under any employee or Director benefit plan of the Company now 
existing or to be implemented in the future, so long as the issuance of such 
stock or options is approved by a majority of the non-employee members of the 
Board of Directors of the Company or a majority of the members of a committee 
of non-employee directors established for such purpose, if there is a change 
at any time in (i) the amount of additional consideration payable to the 
Company upon the exercise of any Options; (ii) the amount of additional 
consideration, if any, payable to the Company upon the exercise, conversion 
or exchange or any Convertible Securities; or (iii) the rate at which any 
Convertible Securities are convertible into or exchangeable for Common Stock 
(other than under or by reason of provisions designed to protect against 
dilution), the Exercise Price in effect at the time of such change will be 
readjusted to the Exercise Price which would have been in effect at such time 
had such Options or Convertible Securities still outstanding provided for 
such changed additional consideration or changed conversion rate, as the case 
may be, at the time initially granted, issued or sold.

          (iv)   Treatment of Expired Options and Unexercised Convertible 
Securities.  If, in any case, the total number of shares of Common Stock 
issuable upon exercise of any Options or upon exercise, conversion or 
exchange of any Convertible Securities is not, in fact, issued and the rights 
to exercise such option or to exercise, convert or exchange such Convertible 
Securities shall have expired or terminated, the Exercise Price then in 
effect will be readjusted to the Exercise Price which would have been in 
effect at the time of such expiration or termination had such Options or 
Convertible Securities, to the extent outstanding immediately prior to such 
expiration or termination (other than in respect of the actual number of 
shares of Common Stock issued upon exercise or conversion thereof), never 
been issued.

          (v)    Calculation of Consideration Received. If any Common Stock, 
Options or Convertible Securities are issued, granted or sold for cash, the 
consideration received therefor the purposes of this Warrant will be the 
amount received by the Company therefor, before deduction of reasonable 
commissions, underwriting discounts or allowances or other reasonable 
expenses paid or incurred by the Company in connection with such issuance, 
grant or sale.  In case any 

                                       6


Common Stock, Options or Convertible Securities are issued or sold for a 
consideration part or all of which shall be other than cash, the amount of 
the consideration other than cash received by the Company will be the fair 
market value of such consideration except where such consideration consists 
of freely-tradeable securities, in which case the amount of consideration 
received by the Company will be the Market Price thereof as of the date of 
receipt.  In case any Common Stock, Options or Convertible Securities are 
issued in connection with any merger or consolidation in which the Company is 
the surviving corporation, the amount of consideration therefor will be 
deemed to be the fair market value of such portion of the net assets and 
business of the non-surviving corporation as is attributable to such Common 
Stock, Options or Convertible Securities, as the case may be.  The fair 
market value of any consideration other than cash or securities will be 
determined in the good faith reasonable business judgment of the Board of 
Directors.

          (vi)   Exceptions to Adjustment of Exercise Price.  No adjustment 
to the Exercise Price will be made (i) upon the exercise of any warrants, 
options or convertible securities issued and outstanding on the date hereof 
in accordance with the terms of such securities as of such date; (ii) upon 
the grant or exercise of any stock or options which may hereafter be granted 
or exercised under any employee or Director benefit plan of the Company now 
existing or to be implemented in the future, so long as the issuance of such 
stock or options is approved by a majority of the non-employee members of the 
Board of Directors of the Company or a majority of the members of a committee 
of non-employee directors established for such purpose; (iii) upon the 
issuance of the Common Shares (as defined in the Securities Purchase 
Agreement) or Warrants in accordance with terms of the Securities Purchase 
Agreement; or (iv) upon the exercise of the Warrants.

     (c)  Subdivision or Combination of Common Stock. If the Company, at any 
time after the initial issuance of this Warrant, subdivides (by any stock 
split, stock dividend, recapitalization, reorganization, reclassifications or 
otherwise) its shares of Common Stock into a greater number of shares, then, 
after the date of record for effecting such subdivision, the Exercise Price 
in effect immediately prior to such subdivision will be proportionately 
reduced.  If the Company, at any time after the initial issuance of this 
Warrant, combines (by reverse stock split, recapitalization, reorganization, 
reclassification or otherwise) its shares of Common Stock into a smaller 
number of shares, then, after the date of record for effecting such 
combination, the Exercise Price in effect immediately prior to such 
combination will be proportionately increased.

     (d)  Adjustment in Number of Shares.  Upon each adjustment of the 
Exercise Price pursuant to the provisions of this Section 4, the number of 
shares of Common Stock issuable upon exercise of this Warrant shall be 
adjusted by multiplying a number equal to the Exercise Price in effect 
immediately prior to such adjustment by the number of shares of Common Stock 
issuable upon exercise of this Warrant immediately prior to such adjustment 
and dividing the product so obtained by the adjusted Exercise Price.

     (e)  Major Transactions.  If the Company shall consolidate with or merge 
into any corporation or sell or convey all or substantially all of its assets 
or reclassify its outstanding shares of Common Stock (other than by way of 
subdivision, or in case of any sale or conveyance of all or substantially all 
of the assets of the Company other than in connection with a plan of complete 
liquidation of the Company, or reduction of such shares) (each a "Major 
Transaction"), 

                                       7


then each holder of a Warrant shall thereafter be entitled to receive 
consideration, in exchange for such Warrant, equal to the greater of, as 
determined in the sole discretion of such older: (i) a warrant to purchase 
(at the same aggregate exercise price and on the same terms and conditions as 
the Warrant surrendered) the number of shares of stock or securities or 
property of the Company, or of the entity resulting from such consolidation 
or merge (the "Major Transaction Consideration"), to which a holder of the 
number of shares of Common Stock delivered upon exercise of such Warrant 
would have been entitled upon such Major Transaction had the holder of such 
Warrant exercised (without regard to any limitations on exercise herein 
contained) the Warrant on the trading date immediately preceding the public 
announcement of the transaction resulting in such Major Transaction and had 
such Common Stock been issued and outstanding and had such holder been the 
holder of record of such Common Stock at the time of such Major Transaction, 
and the Company shall make lawful provision therefor as part of such 
consolidation, merger, sale, conveyance or reclassification; and (ii) cash 
paid by the Company in immediately available funds, in an amount equal to the 
Black-Scholes Amount (as defined herein) times the number of shares of Common 
Stock for which this Warrant was exercisable (without regard to any 
limitations on exercise herein contained) on the date immediately preceding 
the date of such Major Transaction.  No sooner than ten (10) days nor later 
than five (5) days prior to the consummation of the Major Transaction, but 
not prior to the public announcement of such Major Transaction, the Company 
shall deliver written notice ("Notice of Major Transaction") to each holder 
of Warrants, which Notice of Major Transaction shall be deemed to have been 
delivered one (1) business day following the Company's sending such notice by 
telecopy (provided that the Company sends a confirming copy of such notice on 
the same day by overnight courier) of such Notice of Major Transaction. Such 
Notice of Major Transaction shall indicate the amount and type of the Major 
Transaction Consideration which such holder would receive under clause (i) of 
this paragraph (e).  If the Major Transaction Consideration does not consist 
entirely of United States currency, such holder may elect to receive United 
States currency in an amount equal to the value of the Major Transaction 
Consideration in lieu of the Major Transaction Consideration by delivering 
notice of such election to the Company within five (5) days of the holder's 
receipt of the Notice of Major Transaction.  The Company will not effect any 
Major Transaction unless prior to the consummation thereof, the successor 
corporation (if other than the Company) assumes by written instrument the 
obligations under this Section 4 and the obligations to deliver to the Holder 
of this Warrant such shares of stock, securities or assets as, in accordance 
with the foregoing provisions, the Holder may be entitled to acquire.

      The "Black-Scholes Amount" shall be an amount determined by calculating 
the "Black-Scholes" value of an option to purchase one share of Common Stock 
on the applicable page on the Bloomberg online page, using the following 
variable values:  (i) the current market price of the Common Stock equal to 
the closing trade price on the last trading day before the date of the Notice 
of the Major Transaction; (ii) volatility of the Common Stock equal to the 
volatility of the Common Stock during the 100 trading day period preceding 
the date of the Notice of the Major Transaction; (iii) a risk free rate equal 
to the interest rate on the United States treasury bill or treasury note with 
a maturity corresponding to the remaining term of this Warrant on the date of 
the Notice of the Major Transaction; and (iv) an exercise price equal to the 
Exercise Price on the date of the Notice of the Major Transaction.  In the 
event such calculation function is no longer available utilizing the 
Bloomberg online page, the Holder shall calculate such amount in its sole 
discretion using the closest available alternative mechanism and variable 
values to those available utilizing the Bloomberg online page for such 
calculation function.

                                       8


     (f)  Distribution of Assets.  In case the Company shall declare or make 
any distribution of its assets (or rights to acquire its assets) to holders 
of Common Stock as a partial liquidating dividend, by way of return of 
capital or otherwise (including any dividend or distribution to the Company's 
shareholders of cash or shares (or rights to acquire shares) of capital stock 
of a subsidiary) (a "Distribution"), at any time after the initial issuance 
of this Warrant, then the Holder shall be entitled upon exercise of this 
Warrant for the purchase of any or all shares of Common Stock subject hereto, 
to receive the amount of such assets (or rights) which would have been 
payable to the Holder has such Holder been the holder of such shares of 
Common Stock on the record date for the determination of shareholders 
entitled to such Distribution.

     (g)  Notices of Adjustment.  Upon the occurrence of any event which 
requires any adjustment of the Exercise Price, then, and in each such case, 
the Company shall give notice thereof to the Holder, which notice shall state 
the Exercise Price resulting from such adjustment and the increase or 
decrease in the number of Warrant Shares purchaseable at such price upon 
exercise, setting forth in reasonable detail the method of calculation and 
the facts upon which such calculation is based.  Such calculation shall be 
certified by the chief financial officer of the Company.

     (h)  Minimum Adjustment of Exercise Price.  No adjustment of the 
Exercise Price shall be made in an amount of less than 1% of the Exercise 
Price in effect at the time such adjustment is otherwise required to be made, 
but any such lesser adjustment shall be carried forward and shall be made at 
the time and together with the next subsequent adjustment which, together 
with any adjustments so carried forward, shall amount to not less than 1% of 
such Exercise Price.

     (i)  No Fractional Shares.  No fractional shares of Common Stock are to 
be issued upon the exercise of this Warrant, but the Company shall pay a cash 
adjustment in respect of any fractional share which would otherwise be 
issuable in an amount equal to the same fraction of the Market Price of a 
share of Common Stock; provided that in the event that sufficient funds are 
not legally available for the payment of such cash adjustment any fractional 
shares of Common Stock shall be founded up to the next whole number.

     (j)  Other Notices.  In case at any time: 

          (i)    the Company shall declare any dividend upon the Common Stock 
payable in shares of stock of any class or make any other distribution to the 
holders of the Common Stock;

          (ii)   the Company shall offer for subscription pro rata to the 
holders of the Common Stock any additional shares of stock of any class or 
other rights;

          (iii)  there shall be any capital reorganization of the Company, or 
reclassification of the Common Stock, or consolidation or merger of the 
Company with or into, or sale of all or substantially all of its assets to, 
another corporation or entity; or

                                       9


          (iv)   there shall be a voluntary or involuntary dissolution, 
liquidation or winding-up of the Company;

then, in each such case, the Company shall give to the Holder (a) the notice 
of the date on which the books of the Company shall close or a record shall 
be taken for determining the holders of Common Stock entitled to receive any 
such dividend, distribution, or subscription rights or for determining the 
holders of Common Stock entitled to vote in respect of any such 
reorganization, reclassification, consolidation, merger, sale, dissolution, 
liquidation or winding-up and (b) in the case of any such reorganization, 
reclassification, consolidation, merger, sale, dissolution, liquidation or 
winding-up, notice of the date (or, if not then known, a reasonable 
approximation thereof by the Company) when the same shall take place.  Such 
notice shall also specify the date on which the holders of Common Stock shall 
be entitled to receive such dividend, distribution, or subscription rights or 
to exchange their Common Stock for stock or other securities or property 
deliverable upon such reorganization, reclassification, consolidation, 
merger, sale, dissolution, liquidation or winding-up, as the case may be.  
Such notice shall be given at least 30 days prior to the record date or the 
date on which the Company's books are closed in respect thereto, but in no 
event earlier than public announcement of such proposed transaction or event. 
Failure to give any such notice or any defect therein shall not affect the 
validity of the proceedings referred to in clauses (i), (ii), (iii), and (iv) 
above.

     (k)  Certain Events.  If any event occurs of the type contemplated by 
the adjustment provision of this Section 4 but not expressly provided for by 
such provisions, the Company will give notice of such event as provided in 
paragraph 4(g) hereof, and the Company's Board of Directors will make an 
appropriate adjustment in the Exercise Price and the number of shares of 
Common Stock acquirable upon exercise of this Warrant so that the rights of 
the Holder shall neither be enhanced or diminished by such event.

     (l)  Certain Definitions.

          (i)    "Common Stock Deemed Outstanding" shall mean the number of 
shares of Common Stock actually outstanding (not including shares of Common 
Stock held in the treasury of the Company), plus (x) in case of any 
adjustment required by Section 4(a) resulting from the issuance of any 
Options, the maximum total number of shares of Common Stock issuable upon the 
exercise of the Options for which the adjustment is required (including any 
Common Stock issuable upon the conversion of Convertible Securities issuable 
upon the exercise of such Options), and (y) in the case of any adjustment 
required by Section 4(a) resulting from the issuance of any Convertible 
Securities, the maximum total number of shares of Common Stock issuable upon 
the exercise, conversion or exchange of the Convertible Securities for which 
the adjustment is required, as of the date of issuance of such Convertible 
Securities, if any.

          (ii)   "Market Price," as of any date, (i) means the average of the 
Closing Prices for the shares of Common Stock as reported to NASDAQ for the 
five (5) trading days immediately preceding such date, or (ii) if the NASDAQ 
is not the principal trading market for the Common Stock, the average of the 
last reported sale prices on the principal trading market for the Common 
Stock during the same period, or (iii) if market value cannot be calculated 
as off such date on any of the foregoing bases, the Market Price shall be the 
average fair market value 

                                       10


as reasonably determined by an investment banking firm selected by the 
Company and reasonable acceptable to the Holders of a majority in interest of 
the Warrants, with the costs of the appraisal to be borne by the Company.  
The manner of determining the Market Price of the Common Stock set forth in 
the foregoing definition shall apply with respect to any other security in 
respect of which a determination as to market value must be made hereunder.

          (iii)  "Common Stock," for purposes of this Section 4, includes the 
Common Stock and any additional class of stock of the Company having no 
preference as to dividends or distributions on liquidation, provided that the 
shares purchaseable pursuant to this Warrant shall include only Common Stock 
in respect of which this Warrant is exercisable, or shares resulting from any 
subdivision or combination of such Common Stock, or in the case of any 
reorganization, reclassification, consolidation, merger or sale of the 
character referred to in Section 4(d) hereof, the stock or other securities 
or property provided for in such Section.

     5.   Issue Tax.  The issuance of certificates for Warrant Shares upon 
the exercise of this Warrant shall be made without charge to the Holder or 
such shares for any issuance tax or other costs in respect thereof, provided 
that the Company shall not be required to pay any tax which may be payable in 
respect of any transfer involved in the issuance and delivery of any 
certificate in a name other than the Holder.

     6.   No Rights or Liabilities as a Shareholder.  This Warrant shall not 
entitle the Holder to any voting rights or other rights as a shareholder of 
the Company.  No provision of this Warrant, in the absence of affirmative 
action by the Holder to purchase Warrant Shares, and no mere enumeration 
herein of the rights or privileges of the Holder, shall give rise to any 
liability of the Holder for the Exercise Price or as a shareholder of the 
Company, whether such liability is asserted by the Company or by creditors of 
the Company.

     7.   Transfer, Exchange, Redemption and Replacement of Warrant.

     (a)  Restriction of Transfer.  This Warrant and the rights granted to 
the Holder are transferable, in whole or in part, upon surrender of this 
Warrant, together with a properly executed assignment in the Form of 
Assignment attached hereto as Exhibit 2, at the office or agency of the 
Company referred to in Section 7(e) below, provided, however, that any 
transfer or assignment shall be subject to the provisions of Section 5.1 and 
5.2 of the Securities Purchase Agreement.  Until due presentment for 
registration of transfer on the books of the Company, the Company may treat 
the registered holder hereof as the owner and holder hereof for all purposes, 
and the Company shall not be affected by any notice to the contrary. 
Notwithstanding anything to the contrary contained herein, the registration 
rights described in Section 8 hereof are assignable only in accordance with 
the provisions of that certain Registration Rights Agreement, dated as of 
December 12, 1997, by and among the Company and the other signatories thereto 
(the "Registration Rights Agreement").  Upon exercise of this Warrant, the 
Holder will make representations and warranties substantially equivalent to 
the representations and warranties concerning investment intent contained in 
Article II of the Securities Purchase Agreement; provided that any such 
representations and warranties will not cover any investment intent which may 
or may not exist with respect to the resale of the Common Stock upon a 
registration pursuant to the Registration Rights Agreement.  No transfer of 
this Warrant to any investor who

                                       11


is not an accredited investor will be permitted and each Holder agrees that 
such Holder will remain an accredited investor.

     (b)  Warrant Exchangeable for Different Denominations.  This Warrant is 
exchangeable, upon the surrender hereof by the Holder at the office or agency 
of the Company referred to in Section 7(e) below, for new Warrants, in the 
form hereof, of different denominations representing in the aggregate the 
right to purchase the number of shares of Common Stock which may be purchased 
hereunder, each of such new Warrants to represent the right to purchase such 
number of shares as shall be designated by the Holder of at the time of such 
surrender.

     (c)  Replacement of Warrant.  Upon receipt of evidence reasonably 
satisfactory to the Company of the loss, theft, destruction, or mutilation of 
this Warrant or, in the case of any such loss, theft, or destruction, upon 
delivery, of an indemnity agreement reasonably satisfactory in form and 
amount to the Company, or, in the case of any such mutilation, upon surrender 
and cancellation of this Warrant, the Company, at its expense, will execute 
and deliver, in lieu thereof, a new Warrants, in the form hereof, in such 
determinations as Holder may request.

     (d)  Cancellation:  Payment of Expenses.  Upon the surrender of this 
Warrant in connection with any transfer, exchange, or replacement as provided 
in this Section 7, this Warrant shall be promptly canceled by the Company.  
The Company shall pay all issuance taxes (other than securities transfer 
taxes) and charges payable in connection with the preparation, execution, and 
delivery of Warrants pursuant to this Section 7.

     (e)  Warrant Register.  The Company shall maintain, at its principal 
executive offices (or such other office or agency of the Company as it may 
designate by notice to the Holder), a register for this Warrant, in which the 
Company shall record the name and address of the person in whose name this 
Warrant has been issued, as well as the name and address of each transferee 
and each prior owner of this Warrant.

     (f)  Additional Restriction on Exercise or Transfer.  Notwithstanding 
anything to the contrary contained herein, the Warrants shall not be 
exercisable by the Holder to the extent (but only to the extent) that, if 
exercisable by Holder, Holder would beneficially own in excess of 9.9% (the 
"Applicable Percentage") of the shares of Common Stock.  To the extent the 
above limitation applies, the determination of whether the Warrants shall be 
exercisable (vis-a-vis other securities owned by Holder) and of which 
Warrants shall be exercisable (as among Warrants) shall be in the sole 
discretion of the Holder and submission of the Warrants for exercise shall be 
deemed to be the Holder's determination of whether such Warrants are 
exercisable (vis-a-vis other securities owned by Holder) and of which 
warrants are exercisable (among Warrants), in each case subject to such 
aggregate percentage limitation.  No prior inability to exercise Warrants 
pursuant to this paragraph shall have any effect on the applicability of the 
provisions of this paragraph with respect to any subsequent determination of 
exercisability.  For the purposes of this paragraph, beneficial ownership and 
all determinations and calculations, including without limitation, with 
respect to calculations of percentage ownership, shall be determined in 
accordance with Section 13(d) of the Securities Exchange Act of 1934, as 
amended, and Regulation 13D and G thereunder.  The provisions of this 
paragraph may be waived and/or implemented in a manner otherwise than 
strictly in conformity with the foregoing provisions of

                                       12


this paragraph (i) with the approval of the Board of Directors of the Company 
and the Holders:  (i) with respect to any matter to cure any ambiguity 
herein, to correct this paragraph (or any portion hereof) which may be 
defective or inconsistent with the intended Applicable Percentage beneficial 
ownership limitation herein contained or to make changes or supplements 
necessary or desirable to properly give effect to such Applicable Percentage 
limitation; and (ii) with respect to any other matter, with the further 
consent of the holders of a majority of the then outstanding shares of Common 
Stock.  In addition, the provisions of this paragraph (i) may be waived by 
Holder upon ninety (90) days prior written notice from Holder to the Company. 
The limitations contained in this paragraph shall apply to a successor holder 
of Warrants if, and to the extent, elected by such successor holder 
concurrently with its acquisition of such Warrants, such election to be 
promptly confirmed in writing to the Company (provided no transfer or series 
of transfer to a successor holder or holders shall be used by a Holder to 
evade the limitations contained in this paragraph).

     8.   Registration Rights.  The initial holder of this Warrant (and 
certain assignees thereof) is entitled to the benefit of such registration 
rights in respect of the Warrant Shares as are set forth in the Registration 
Rights Agreement.

     9.   Notices.  Any notice herein required or permitted to be given shall 
be in writing and may be personally served or delivered by courier (including 
a recognized overnight delivery service) or by confirmed telecopy, and shall 
be deemed delivered at the time and date of receipt (which shall include 
telephone line facsimile transmission).  The addresses for such 
communications shall be:

          If to the Company:
          
               Biospherics Incorporated
               12051 Indian Creek Court
               Beltsville, MD  20705
               Telecopy:  301-210-4908
               Attention:  Dr. Gilbert V. Levin
               
                      with a copy to:
               
               Smith, Somerville & Case, L.L.C.
               Attorneys At Law
               100 Light Street
               Baltimore, MD  21202
               Telecopy:  410-385-8060
               Attention:  James Baker, Esq.
               
and if to the Holder, at such address as Holder shall have provided in 
writing to the Company, or at such other address as each party furnishes by 
notice given in accordance with this Section 9.

     11.  Governing Law: Jurisdiction.  This Warrant shall be governed by and 
construed in accordance with the laws of the State of Delaware applicable to 
contracts made and to be performed in the State of Delaware.  The Company 
irrevocably consents to the jurisdiction of the 

                                       13


United States federal courts located in the County of New Castle in the State 
of Delaware in any suit or proceeding based on or arising under this Warrant 
and irrevocably agrees that all claims in respect of such suit or proceeding 
may be determined in such courts.  The Company irrevocably waives the defense 
of an inconvenient forum to the maintenance of such suit or proceeding. The 
Company agrees that a final non-appealable judgment in any such suit or 
proceeding shall be conclusive and may be enforced in other jurisdictions by 
suit on such judgment or in any other lawful manner.

     12.  Miscellaneous.

     (a)  Amendments.  This Warrant and any provision hereof may only be 
amended by an instrument in writing signed by the Company and the Holder.

     (b)  Descriptive Headings.  The descriptive headings of the several 
Sections of this Warrant are inserted for purposes of reference only, and 
shall not affect the meaning or construction of any of the provisions hereof.

     (c)  Cashless Exercise.  Notwithstanding anything to the contrary 
contained in this Warrant, this Warrant may be exercised by presentation and 
surrender of this Warrant to the Company at its principal executive offices 
with a written notice of the Holder's intention to effect a cashless 
exercise, including a calculation of the number of shares of Common Stock to 
be issued upon such exercise in accordance with the terms hereof (a "Cashless 
Exercise").  In the event of a Cashless Exercise, in lieu of paying the 
Exercise Price in cash, the Holder shall surrender this Warrant for the 
number of shares of Common Stock determined by multiplying the number of 
Warrant Shares to which it would otherwise be entitled by a fraction, the 
numerator of which shall be the difference between the then current Market 
Price per share of the Common Stock and the Exercise Price, and the 
denominator of which shall be such then current Market Price per share of 
Common Stock.

     (d)  Assignability.  This Warrant shall be binding upon the Company and 
its successors and assigns and shall inure to the benefit of Holder and its 
successors and assigns.  The Holder shall notify the Company upon the 
assignment of this Warrant.

                                   * * * * *

     IN WITNESS WHEREOF, the Company has caused this Warrant to be signed by 
its duly authorized officer.

                                       BIOSPHERICS INCORPORATED

                                   By:
                                      --------------------------------

                                   Name:
                                         -----------------------------

                                   Title:
                                         -----------------------------

                                       14


                         FORM OF EXERCISE AGREEMENT

          (To be Executed by the Holder in order to Exercise the Warrant)

     The undersigned hereby irrevocably exercises the right to purchase 
____________ of the shares of common stock of Biospherics Incorporated, a 
Delaware corporation (the "Company"), evidenced by the attached Warrant, and 
herewith makes payment of the Exercise Price with respect to such shares in 
full or, if the resale of the Common Stock by the undersigned is not 
currently registered pursuant to an effective registration statement under 
the Securities Act of 1933, as amended, elects to effect a Cashless Exercise 
pursuant to the terms of the Warrant, all in accordance with the conditions 
and provisions of said Warrant.

     (i)  The undersigned agrees not to offer, sell, transfer or otherwise 
dispose of any Common Stock obtained on exercises of the Warrant, except 
under circumstances that will not result in a violation of the Securities Act 
of 1933, as amended, or any state securities laws.

     (ii) The undersigned requests that stock certificates for such shares be 
issued, and a Warrant representing any unexercised portion hereof be issued, 
pursuant to the Warrant in the name of the Holder (or such other person or 
persons indicated below) and delivered to the undersigned (or designee(s) at 
the address (or addresses) set forth below:

Date:
     ------------------------          ----------------------------------
                                       Signature of Holder


                                       ----------------------------------
                                       Name of Holder (Print)

                                       Address:

                                       ----------------------------------

                                       ----------------------------------

                                       15



                               FORM OF ASSIGNMENT

     FOR VALUE RECEIVED, the undersigned hereby sells, assigns, and transfers 
all rights of the undersigned under the within Warrant, with respect to the 
number of shares of Common Stock covered thereby set forth herein below, to:

Name of Assignee                 Address                 No. of Shares
- ----------------                 -------                 -------------

, and hereby irrevocably constitutes and appoints _____________________________
as agent and attorney-in-fact to transfer said Warrant on the books of the
within-named corporation, with full power of substitution in the premises.

Date:
      ---------------------, -----------

In the presence of:

- ----------------------------------------

                                    Name:
                                         -------------------------------

                                    Signature:
                                              --------------------------

                                    Title of Signing Officer or Agent (if any):

                                    ------------------------------------

                                    Address:
                                            ----------------------------

                                    ------------------------------------

                                    Note: The above signature should
                                          correspond exactly with the name
                                          on the face of the within Warrant.

                                       16