CERTIFIED COPY OF RESOLUTIONS I do hereby certify that I am the duly elected, qualified, and acting (Assistant) Secretary of CYGNUS, INC., a Delaware corporation, and, as such, have custody of the records of the Corporation, including the minutes of the meeting of the Board of Directors of said corporation duly called and held on October 11, 1994, at which a quorum was present and acting throughout and at which the following resolutions were duly adopted. I further certify that said resolutions are in full force and effect as of the date hereof and have not been modified or rescinded in any manner whatsoever. RESOLVED, that the President, any Vice President, any Assistant Vice President, the Treasurer, any Assistant Treasurer, Director, Finance & Acctg, or ______________________, each has full authority to execute and deliver in the name and on behalf of the Corporation, instruments, documents, and agreements, including amendments, renewals, or extensions thereof, with HELLER FINANCIAL, INC. ("Lender"), providing for various financing arrangements with the Corporation, including but not limited to, the leasing of equipment by, and financing the acquisition of equipment for, the Corporation, the borrowing of monies and the pledging, mortgaging, or otherwise encumbering of any or all of the Corporation's assets pursuant to any sale and leaseback or other financing arrangement, with or without recourse to the Corporation, all upon terms and conditions and containing such provisions as such officer(s), employee(s), or agent(s) may in her or their sole discretion deem advisable, necessary, or expedient; and FURTHER RESOLVED, that the authority herein conferred shall be deemed retroactive and any and all acts authorized hereunder performed prior to the date hereof are hereby approved and ratified; and that nothing herein contained shall be deemed to affect the authority heretofore or hereafter conferred upon any other person or persons, it being understood and agreed that the authority herein conferred shall continue in full force and effect until written notice to the contrary shall be actually received by Lender. I further certify that there is no provision in the charter or by-laws of the Corporation limiting the power of the Board of Directors to adopt the foregoing resolutions, that the same are in conformity with the provisions of said charter and by-laws, and that no shareholder consent is required to permit the action provided for thereby. I further certify that the persons whose names, titles, and signatures appear below are elected or appointed, qualified, and acting officer(s), employee(s), or agent(s) of the Corporation and hold on the date of this certificate the office or position set forth opposite their respective names, and the signatures appearing opposite their respective names are the genuine signatures of such officer(s), employee(s), or agent(s). NAME TITLE OR POSITION SIGNATURE CFO, VP Finance John C. Hodgman President, Cygnus Diagnostics /s/ John C. Hodgman ____________________ _____________________________ ______________________ Director, Finance Frank A. Raab and Accounting /s/ Frank A. Raab ____________________ _____________________________ ______________________ ____________________ _____________________________ ______________________ ____________________ _____________________________ ______________________ ____________________ _____________________________ ______________________ ____________________ _____________________________ ______________________ IN WITNESS WHEREOF, I have hereunto set my hand and affixed the seal of the Corporation this 27th day of June, 1997. CYGNUS, INC. [ILLEGIBLE] (NAME) CORPORATE SEAL [ASSISTANT] SECRETARY Loan No.: 1910128-0001 - ------------------------------------------------------------------------------- HELLER FINANCIAL SECURITY AGREEMENT THIS SECURITY AGREEMENT ("AGREEMENT") is made this 27th day of June, 1997, by and between CYGNUS, INC., a Delaware corporation ("DEBTOR"), whose business address is 400 Penobscot Drive, Redwood City, California 94063 and HELLER FINANCIAL, INC., a Delaware corporation ("SECURED PARTY"), whose address is Commercial Equipment Finance Division, 500 West Monroe Street, Chicago, Illinois 60661. WITNESSETH: 1. SECURE PAYMENT. To secure payment of indebtedness in the principal sum of up to One Million Five Hundred Thousand and 00/100 Dollars ($1,500,000.00), as evidenced by a note or notes executed and delivered by Debtor to Secured Party (the "NOTES") and any obligations arising under this Agreement, and also to secure any other indebtedness or liability of Debtor to Secured Party, direct or indirect, absolute or contingent, due or to become due, now existing or hereafter arising and no matter how acquired by Secured Party, including all future advances or loans which may be made at the option of Secured Party (all the foregoing hereinafter called the "INDEBTEDNESS"), Debtor hereby grants and conveys to Secured Party a first priority continuing lien and security interest in the personal property described on any schedule(s) now or hereafter attached to or made a part hereof by reference hereto (the "SCHEDULES"), all products and proceeds (including insurance proceeds) thereof, if any, and all substitutions, replacements, attachments, additions, and accessions thereto (all of the foregoing hereinafter called the "COLLATERAL.") The Schedules may be supplemented from time to time to evidence the Collateral subject to this Agreement. Debtor shall request in writing each advance of principal under the Notes, which request shall be satisfactory to Secured Party in form and substance. Each advance shall be on and subject to the terms and conditions set forth in this Agreement and shall otherwise be at Secured Party's sole discretion. Each Note shall be in an amount not less than $500,000.00. No principal advance under any Notes shall be made after July 31, 1997, and each advance shall reduce, dollar for dollar, the amount that may be advanced under the Notes in the aggregate. Amounts advanced and repaid may not be reborrowed. 1 2. REPRESENTATIONS, WARRANTIES AND COVENANTS. Except as otherwise provided, each representation and warranty made by Debtor in this Agreement shall be true, correct and complete as of the date of this Agreement and as of the date of each advance of funds under a Note. Debtor hereby represents, warrants and covenants as follows: (a) PERFORM OBLIGATIONS. Debtor shall pay as and when due all Indebtedness secured by this Agreement and perform all of the obligations contained in this Agreement according to its terms. Debtor shall use the loan proceeds for business uses and not for personal, family, household, or agricultural uses. (b) PERFECTION. This Agreement and all necessary Uniform Commercial Code filings together create a valid, perfected and first priority continuing lien and security interest in the Collateral, securing the payment and performance of the Indebtedness, and all filings and other actions necessary or desirable to create, perfect and protect such security interest have been or will be duly taken. (c) COLLATERAL FREE AND CLEAR. Except as may be set forth on a Schedule, the Collateral is and shall remain free and clear of all liens, claims, charges, encumbrances and other security interests of any kind (other than the security interest granted hereby). Debtor shall defend the title to the Collateral against all persons and against all claims and demands whatsoever. (d) POSSESSION AND OPERATING ORDER OF THE COLLATERAL. Debtor shall retain possession of the Collateral at all times and shall not sell, exchange, assign, loan, deliver, lease, mortgage, or otherwise dispose of the Collateral or any part thereof without the prior written consent of Secured Party. Debtor shall at all times keep the Collateral at the location[s] specified on the Schedules (except for removals thereof in the usual course of business for temporary periods). At Debtor's sole cost and expense, Debtor shall keep the Collateral in good repair and condition and shall not misuse, abuse, waste or otherwise allow it to deteriorate, except for normal wear and tear. Secured Party may verify any Collateral in any reasonable manner which Secured Party may consider appropriate, and Debtor shall furnish all reasonable assistance and information and perform any acts which Secured Party may reasonably request in connection therewith. (e) INSURANCE. Debtor shall insure the Collateral against loss by fire (including extended coverage), theft and other hazards, for its full insurable value including replacement costs, with a deductible not to exceed Fifty 2 Thousand and 00/100 Dollars ($50,000.00) per occurrence and without co-insurance. In addition, Debtor shall obtain liability insurance covering liability for bodily injury, including death and property damage, in an amount of at least Five Million and 00/100 Dollars ($5,000,000.00) per occurrence or such greater amount as may comply with general industry standards, or in such other amounts as Secured Party may otherwise require. All policies of insurance required hereunder shall be in such form, amounts, and with such companies as Secured Party may approve; shall provide for at least thirty (30) days prior written notice to Secured Party prior to any modification or cancellation thereof; shall name Secured Party as loss payee or additional insured, as applicable, and shall be payable to Debtor and Secured Party as their interests may appear; shall waive any claim for premium against Secured Party; and shall provide that no breach of warranty or representation or act or omission of Debtor shall terminate, limit or affect the insurers' liability to Secured Party. Certificates of insurance or policies evidencing the insurance required hereunder along with satisfactory proof of the payment of the premiums therefor shall be delivered to Secured Party. Debtor shall give immediate written notice to Secured Party and to insurers of loss or damage to the Collateral and shall promptly file proofs of loss with insurers. To the extent related to the Collateral or liability or alleged liability of Secured Party, Debtor hereby irrevocably appoints Secured Party as Debtor's attorney-in-fact, coupled with an interest, for the purpose of obtaining, adjusting and canceling any such insurance and endorsing settlement drafts. Debtor hereby assigns to Secured Party, as additional security for the Indebtedness, all sums which may become payable under such insurance. In the event Debtor fails to provide Secured Party with evidence of the insurance coverage required by this Agreement, Secured Party may purchase insurance at Debtor's expense to protect Secured Party's interests in the Collateral. This insurance may, but need not, protect Debtor's interests. The coverage purchased by Secured Party may not pay any claim made by Debtor or any claim that is made against Debtor in connection with the Collateral. Debtor may later cancel any insurance purchased by Secured Party, but only after providing Secured Party with evidence that Debtor has obtained insurance as required by this Agreement. If Secured Party purchases insurance for the Collateral, Debtor will be responsible for the costs of that insurance, including interest and other charges imposed by Secured Party in connection with the placement of the insurance, until the effective date of the cancellation or expiration of the insurance. The costs of the insurance may be added to the Indebtedness. The costs of the insurance may be more than the cost of insurance Debtor is able to obtain on its own. 3 (f) IF COLLATERAL ATTACHES TO REAL ESTATE. If the Collateral or any part thereof has been attached to or is to be attached to real estate, an accurate description of the real estate and the name and address of the record owner is set forth on the Schedules. Debtor shall, on demand of Secured Party, furnish Secured Party with a disclaimer or waiver of any interest in any such Collateral satisfactory to Secured Party and signed by all persons having an interest in the real estate. Notwithstanding the foregoing, the Collateral shall remain personal property and shall not be affixed to realty without the prior written consent of Secured Party. (g) FINANCIAL STATEMENTS. Debtor shall furnish to Secured Party, as soon as practicable, and in any event within sixty (60) days after the end of each fiscal quarter of Debtor and each guarantor of all or any part of the Indebtedness (each, a "GUARANTOR"), respectively, Debtor's and each Guarantor's unaudited financial statements including in each instance, balance sheets, income statements, and statements of cash flow, on a consolidated and consolidating basis, as appropriate, and separate profit and loss statements as of and for the quarterly period then ended and for the respective person's fiscal year to date, prepared in accordance with generally accepted accounting principles, consistently applied ("GAAP"). Debtor shall also furnish to Secured Party, as soon as practicable, and in any event within ninety (90) days after the end of each fiscal year of Debtor and each Guarantor, respectively, Debtor's and each Guarantor's annual audited financial statements, including balance sheets, income statements and statements of cash flow for the fiscal year then ended, on a consolidated and consolidating basis, as appropriate, which have been prepared by its independent accountants in accordance with GAAP. Such audited financial statements shall be accompanied by the independent accountant's opinion, which opinion shall be in form generally recognized as "unqualified". (h) AUTHORIZATION. Debtor is now, and will at all times remain, duly licensed, qualified to do business and in good standing in every jurisdiction where failure to be so licensed or qualified and in good standing would have a material adverse effect on its business, properties or assets. The execution and delivery of this Agreement, the Notes and any other documents and instruments executed contemporaneously with or delivered pursuant to this Agreement and the Notes, all as amended from time to time (collectively the "LOAN DOCUMENTS"), have been duly authorized by Debtor and constitute the legal, valid, and binding obligations of Debtor, enforceable against Debtor in accordance with their respective terms. Debtor shall preserve and maintain its existence and shall not wind up its affairs or otherwise dissolve. Debtor shall not, without thirty (30) days prior written notice to Secured Party, (1) change its name or so change its structure such that any financing statement or other record notice becomes misleading or (2) change its principal place of 4 business or chief executive or accounting offices from the address stated herein. (i) LITIGATION. Except for the arbitration before the International Chamber of Commerce known as ICC No. 8309/HV, involving Cygnus Therapeutic Systems, Inc. and Sanofi, S.A. (the "SANOFI ARBITRATION"), and otherwise as disclosed by Debtor on a Schedule, there are no judgments outstanding against or affecting Debtor, its officers, directors or affiliates or any part of the Collateral and there are no actions, charges, claims, demands, suits, proceedings, or investigations pending or threatened against Debtor or otherwise affecting any part of the Collateral ("LITIGATION"). Debtor shall furnish to Secured Party all information regarding any material Litigation as Secured Party shall reasonably request and in any event shall promptly notify Secured Party in writing of any Litigation against it which if decided against it would materially and adversely affect the finances or operations of Debtor. For the purposes of this subsection 2(i), Five Hundred Thousand and 00/100 Dollars ($500,000.00) shall be deemed material. (j) NO CONFLICTS. Debtor is not in violation of any material term or provision of its by-laws, or of any material agreement or instrument, decree, order, or any statute, rule, or governmental regulation applicable to it. The execution, delivery, and performance of the Loan Documents do not and will not violate, constitute a default under, or otherwise conflict with any such term or provision or result in the creation of any security interest, lien, charge, or encumbrance upon any of the properties or assets of Debtor, except for the security interest created hereunder. (k) COMPLIANCE WITH LAWS. Debtor shall use and maintain the Collateral in accordance with all applicable laws, regulations, ordinances, and codes and shall otherwise comply in all material respects with all applicable laws, rules, and regulations and duly observe all valid requirements of all governmental authorities, and all statutes, rules and regulations relating to its business as now in effect and which may be imposed in the future. (l) TAXES. Debtor has timely filed all tax returns (federal, state, local, and foreign) required to be filed by it and has paid or established reserves for all taxes, assessments, fees, and other governmental charges in respect of its properties, assets, income and franchises. Debtor shall promptly file, pay and discharge all taxes, assessments, license fees (related to the Collateral) and other governmental charges prior to the date on which penalties are attached thereto, establish adequate reserves for the payments of such taxes, assessments, and other governmental charges and make all required withholding and other tax deposits, and, upon request, provide Secured Party 5 with receipts or other proof that any or all of such taxes, assessments, license fees or governmental charges have been paid in a timely fashion; provided, however, that nothing contained herein shall require the payment of any tax, assessment, or other governmental charge so long as its validity is being diligently contested in good faith and by appropriate proceedings diligently conducted and Debtor has established cash reserves therefor in accordance with GAAP. Should any stamp, excise, or other tax, including mortgage, conveyance, deed, intangible, or recording taxes become payable in connection with or respect of any of the Loan Documents, Debtor shall pay the same (including interest and penalties, if any) and shall hold Secured Party harmless with respect thereto. (m) ENVIRONMENTAL LAWS/COMPLIANCE. Except as disclosed by Debtor on a Schedule, Debtor (1) has not received any claim, summons, complaint, order, or other notice that it is not in compliance with, or that any public authority is investigating its compliance with, any federal, state, and local laws, rules, regulations, orders, and decrees relating to pollution, hazardous substances, waste, disposal or the protection of human health or safety, plant life or animal life, natural resources or the environment, all as amended from time to time (collectively, "Environmental Laws"), (2) has no knowledge of any material violation of any Environmental Laws on or about its assets or property, and (3) is not under any current clean up or other remediation program or order. Debtor has obtained all environmental, health and safety permits necessary for the operation of Debtor's business. Debtor is and shall remain in compliance, in all respects, with the terms and conditions of all permits and with all applicable Environmental Laws. Debtor shall provide Secured Party, promptly following receipt, copies of any correspondence, notice, complaint, order, or other document that it receives asserting or alleging a circumstance or condition which requires or may require a cleanup, removal, remedial action or other response by or on the part of Debtor under any Environmental Laws, or which seeks damages or civil, criminal or punitive penalties from Debtor for an alleged violation of any Environmental Laws. Debtor will promptly notify Secured Party of any release, spill or material change in the nature or extent of any hazardous substances or contaminants used, transported or stored by Debtor or any subsidiary of Debtor, and allow no material change in the use thereof or of Debtor's operations that would increase in any material amount the risk of violation of any Environmental Laws without the express prior written approval of Secured Party. (n) REGULATIONS. No proceeds of the loans or any other financial accommodation hereunder will be used, directly or indirectly, for the purpose of purchasing or carrying any margin security, as that term is defined in 6 Regulations G, T, U, X of the Board of Governors of the Federal Reserve System. (o) BOOKS AND RECORDS. Debtor shall maintain, at all times, true and complete books and records in accordance with GAAP and consistent with those applied in the preparation of Debtor's financial statements. At all reasonable times, upon reasonable notice, and during normal business hours, Debtor shall permit Secured Party or its agents to audit, examine and make extracts from or copies of any of its books, ledgers, reports, correspondence, and other records relating to the Collateral. (p) SETOFF. Without limiting any other right of Secured Party, whenever Secured Party has the right to declare any Indebtedness to be immediately due and payable (whether or not it has so declared), Secured Party is hereby authorized at any time and from time to time to the fullest extent permitted by law, but shall not be obligated to, set off and apply against any and all Indebtedness, any and all monies then or thereafter owed to Debtor by Secured Party, whether or not the obligation to pay such monies owed by Secured Party is then due. An election by Secured Party to exercise its right of setoff shall be effective immediately upon such election even though any charge therefor is made or entered on Secured Party's records subsequent thereto. (q) STANDARD OF CARE; NOTICE OF CLAIMS. Debtor acknowledges and agrees that Secured Party shall not be liable for any acts or omissions nor for any error of judgment or mistake of fact or law other than as a sole and direct result of Secured Party's gross negligence or willful misconduct. Debtor shall give Secured Party written notice of any action or inaction by Secured Party or any agent or attorney of Secured Party that may give rise to a claim against Secured Party or any agent or attorney of Secured Party or that may be a defense to payment of the Indebtedness or performance hereunder for any reason, including commission of a tort (subject, in any event, to the first sentence of this paragraph) or violation of any contractual duty or duty implied by law. Debtor agrees that unless such notice is fully given as promptly as possible (and in any event within thirty (30) days) after Debtor has knowledge, or with the exercise of reasonable diligence should have had knowledge, of any such action or inaction, Debtor shall not assert, and Debtor shall be deemed to have waived, any claim or defense arising therefrom. (r) INDEMNITY. Debtor shall indemnify, defend and hold Secured Party, its parent, affiliates, officers, directors, agents, employees, consultants, persons engaged by Secured Party to evaluate or monitor the Collateral, auditors and attorneys harmless from and against any loss, cost, expense (including reasonable attorneys' fees and costs and any consultants' or other 7 experts' fees and expenses), damage, penalty, fine, claim, lien, suit, judgment or liability of every kind and nature arising directly or indirectly out of (i) any Loan Document, (ii) the ownership, possession, lease, operation, use, condition, sale, return, or other disposition of the Collateral, except to the extent the loss, expense, damage or liability arises solely and directly from Secured Party's gross negligence or willful misconduct, (iii) any Environmental Laws, and (iv) the enforcement by Secured Party of its rights or remedies hereunder. Any payments required to be made hereunder shall be due and payable on demand. (s) PAYMENTS SET ASIDE. If any payment is made to Secured Party or Secured Party enforces its security interest or exercises its right of set off, and such payment or part, or any proceeds of such enforcement or set off are subsequently invalidated, declared to be fraudulent or preferential, set aside and/or required to be repaid to a trustee, receiver or any other party under any bankruptcy law, state or federal law, common law or equitable cause, then to the extent of such recovery, the Indebtedness or part thereof originally intended to be satisfied, and all liens, security interests, rights and remedies therefor, shall be revived and continued in full force and effect as if such payment had not been made or such enforcement or set off had not occurred. (t) EXPENSES AND ATTORNEYS' FEES. Debtor shall be liable for all charges, costs, expenses and attorneys' fees incurred by Secured Party (including allocated costs of internal counsel): (i) in perfecting, defending, protecting or terminating its security interest in the Collateral, or any part thereof; (ii) in the negotiation, execution, delivery, administration, amendment or enforcement of the Loan Documents or the collection of any amounts due under any Note or other Loan Document; (iii) in any lawsuit or other legal proceeding in any way connected with any of the Loan Documents, including any contract or tort or other actions, any arbitration or other alternative dispute resolution proceeding, all appeals and judgment enforcement actions and any bankruptcy proceeding (including any relief from stay and/or adequate protection motions, cash collateral disputes, assumption/rejection motions and disputes or objections to any proposed disclosure statement or reorganization plan). (u) COMPLETE INFORMATION. No representation or warranty made by Debtor in any Loan Document and no other document or statement now or hereafter furnished to Secured Party by or on behalf of Debtor contains or will contain any misstatement of a material fact or omit to state any material fact which would make the statements contained therein misleading. Except as expressly set forth in the Schedules, there is no fact known to Debtor that has or could have a materially adverse affect on the business, operation, 8 condition (financial or otherwise), performance, properties or prospects of Debtor or Debtor's ability to timely pay all of the Indebtedness and perform all of its other obligations contained in or secured by this Agreement. (v) COLLATERAL DOCUMENTATION. Debtor shall deliver to Secured Party prior to any advance, satisfactory documentation regarding the Collateral to be financed, including such invoices, canceled checks evidencing payments, or other documentation as may be reasonably requested by Secured Party. Additionally, Debtor shall satisfy Secured Party that Debtor's business and financial information is as has been represented and there has been no material change in Debtor's business, financial condition, or operations. 3. PREPAYMENT. Upon forty-five (45) days prior written notice to Secured Party, Debtor may prepay in whole, but not in part, the then entire unpaid principal balance of any Note, together with all accrued and unpaid interest thereon to the date of such prepayment, provided that in addition to such prepayment, Debtor shall pay (i) any and all other sums then due under any of the Loan Documents, and (ii) a prepayment fee as liquidated damages and not as a penalty, in a sum equal to one percent (1%) of the principal balance prepaid for each full or partial twelve (12) month period by which the date of the prepayment precedes the scheduled date of the final installment of principal under the Note. The prepayment fee described in clause (ii) above shall also be due upon the acceleration of the maturity date of any Note following the occurrence of any Event of Default. 4. EVENTS OF DEFAULT. If any one of the following events (each of which is herein called an "EVENT OF DEFAULT") shall occur: (a) Debtor fails to pay any part of the Indebtedness within ten (10) calendar days of its due date, or (b) any warranty or representation of Debtor in any Loan Document is materially untrue, misleading or inaccurate, or (c) Debtor breaches or defaults in the performance of any obligation under Section 2(c), (d) or (e) of this Agreement, or (d) Debtor or any Guarantor breaches or defaults in the performance of any other agreement or covenant under any Loan Document (other than as specified in clauses (a), (b) and (c) of this Section 4), and such breach or default shall continue for a period of thirty (30) days without being cured, or (e) Debtor or any Guarantor breaches or defaults in the payment or performance of any debt or other obligation owed by it to Secured Party or any affiliate of Secured Party, and Secured Party has (without being obligated to do so) declared such event, an Event of Default hereunder, or (f) Debtor breaches or defaults in the payment or performance of any debt or other obligation, whether now or hereafter existing, with an outstanding principal balance in excess of One Million and 00/100 Dollars ($1,000,000.00), and the same is subsequently accelerated, or (g) there shall be a change in the beneficial ownership and control, directly or indirectly, of the majority of 9 the outstanding voting securities or other interests entitled (without regard to the occurrence of any contingency) to elect or appoint members of the board of directors or other managing body of Debtor or any Guarantor (a "CHANGE OF CONTROL"), or there is any merger, consolidation, dissolution, liquidation, winding up or sale or other transfer of all or substantially all of the assets of Debtor or any Guarantor pursuant to which there is a change of control or cessation of Debtor or the Guarantor or the business of either, or (h) other than pursuant to a decision rendered in the Sanofi Arbitration, any money judgment is entered or filed against Debtor or any Guarantor in excess of One Million and 00/100 Dollars ($1,000,000.00), or (i) Debtor or any Guarantor shall file a voluntary petition in bankruptcy, shall apply for or permit the appointment by consent or acquiescence of a receiver, conservator, administrator, custodian or trustee for itself or all or a substantial part of its property, shall make an assignment for the benefit of creditors or shall be unable, fail or admit in writing its inability to pay its debts generally as such debts become due, or (j) there shall have been filed against Debtor or any Guarantor an involuntary petition in bankruptcy or Debtor or any Guarantor shall suffer or permit the involuntary appointment of a receiver, conservator, administrator, custodian or trustee for all or a substantial part of its property or the issuance of a warrant of attachment, diligence, execution or similar process against all or any substantial part of its property; unless, in each case, such petition, appointment or process is fully bonded against, vacated or dismissed within forty-five (45) days from its effective date, but no later than ten (10) days prior to any proposed disposition of any assets pursuant to any such proceeding, or (k) if there is a material adverse change in the business or financial condition or prospects of Debtor, or any Guarantor, then, and in any such event, Secured Party shall have the right to exercise any one or more of the remedies hereinafter provided. Each of the following events shall also constitute an Event of Default hereunder and upon the occurrence of any one or more of them, Secured Party shall have the right to exercise any one or more of the remedies hereinafter provided: (aa) If Debtor at any time has less than Fifteen Million Dollars ($15,000,000.00) of cash and cash equivalents on hand; (bb) If Debtor at any time has a tangible net worth as determined in accordance with GAAP (but excluding trademarks, service marks, patents, patent rights, capitalized development costs, monies due from affiliates of Debtor or shareholders of Debtor or affiliates of Debtor, goodwill and similar intangible assets) of less than Twelve Million Dollars ($12,000,000.00); or 10 (cc) If, pursuant to a decision rendered in the Sanofi Arbitration, Debtor is obligated to pay a liquidated sum in excess of $15,000,000.00 (whether or not additional relief is also awarded). 5. REMEDIES. Upon the occurrence of an Event of Default, in addition to all rights and remedies of a secured party under the Uniform Commercial Code, Secured Party may, at its option, at any time (a) declare the Indebtedness to be immediately due and payable; (b) without demand or legal process, enter the premises where the Collateral may be found and take possession of and remove the Collateral, all without charge to or liability on the part of Secured Party; or (c) require Debtor to assemble the Collateral, render it unusable, and crate, pack, ship, and deliver the Collateral to Secured Party in such manner and at such place as Secured Party may require, all at Debtor's sole cost and expense. DEBTOR HEREBY EXPRESSLY WAIVES ITS RIGHTS, IF ANY, TO (1) PRIOR NOTICE OF REPOSSESSION AND (2) A JUDICIAL OR ADMINISTRATIVE HEARING PRIOR TO SUCH REPOSSESSION. Secured Party may, at its option, ship, store and repair the Collateral so removed and sell any or all of the Collateral at a public or private sale or sales. Unless the Collateral is perishable or threatens to decline speedily in value or is of a type customarily sold on a recognized market, Secured Party will give Debtor reasonable notice of the time and place of any public sale thereof or of the time after which any private sale or any other intended disposition thereof is to be made, it being understood and agreed that Secured Party may be a buyer at any such sale and Debtor may not, either directly or indirectly, be a buyer at any such sale. The requirements, if any, for reasonable notice will be met if such notice is mailed postage prepaid to Debtor at its address shown above, at least five (5) days before the time of sale or disposition. After any such sale or disposition, Debtor shall be liable for any deficiency of the Indebtedness remaining unpaid, with interest thereon at the rate set forth in the related Notes. 6. CUMULATIVE REMEDIES/MARSHALING. All remedies of Secured Party hereunder are cumulative, are in addition to any other remedies provided for by law or in equity, or under any other provision of any of the Loan Documents, or under the provisions of any other document, instrument or other writing executed by Debtor or any third party in favor of Secured Party, all of which may, to the extent permitted by law, be exercised concurrently or separately, and the exercise of any one remedy shall not be deemed an election of such remedy or to preclude the exercise of any other remedy. No failure on the part of Secured Party to exercise, and no delay in exercising any right or remedy, shall operate as a waiver thereof or in any way modify or be deemed to modify the terms of this Agreement or any other Loan Document or the Indebtedness, nor shall any single or partial exercise by Secured Party of any right or remedy preclude any other or further exercise 11 of the same or any other right or remedy. Secured Party shall not be under any obligation to marshal any assets in favor of Debtor, any Guarantor or any other person or against or in payment of any or all of the Indebtedness. 7. ASSIGNMENT. Secured Party may transfer or assign all or any part of the Indebtedness and the Loan Documents without releasing Debtor or the Collateral, and upon such transfer or assignment the assignee or holder shall be entitled to all the rights, powers, privileges and remedies of Secured Party to the extent assigned or transferred. The obligations of Debtor shall not be subject, as against any such assignee or transferee, to any defense, set-off, or counter-claim available to Debtor against Secured Party and any such defense, set-off, or counter-claim may be asserted only against Secured Party. 8. TIME IS OF THE ESSENCE. Time and manner of performance by Debtor of its duties and obligations under the Loan Documents is of the essence. If Debtor shall fail to comply with any provision of any of the Loan Documents, Secured Party shall have the right, but shall not be obligated, to take action to address such non-compliance, in whole or in part, and all moneys spent and expenses and obligations incurred or assumed by Secured Party shall be paid by Debtor upon demand and shall be added to the Indebtedness. Any such action by Secured Party shall not constitute a waiver of Debtor's default. 9. ENFORCEMENT. THIS AGREEMENT SHALL BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH THE INTERNAL LAWS AND DECISIONS OF THE STATE OF ILLINOIS, WITHOUT REGARD TO PRINCIPLES OF CONFLICTS OF LAW. AT SECURED PARTY'S ELECTION AND WITHOUT LIMITING SECURED PARTY'S RIGHT TO COMMENCE AN ACTION IN ANY OTHER JURISDICTION, DEBTOR HEREBY SUBMITS TO THE EXCLUSIVE JURISDICTION AND VENUE OF ANY COURT (FEDERAL, STATE OR LOCAL) HAVING SITUS WITHIN THE STATE OF ILLINOIS, EXPRESSLY WAIVES PERSONAL SERVICE OF PROCESS AND CONSENTS TO SERVICE BY CERTIFIED MAIL, POSTAGE PREPAID, DIRECTED TO THE LAST KNOWN ADDRESS OF DEBTOR, WHICH SERVICE SHALL BE DEEMED COMPLETED WITHIN TEN (10) DAYS AFTER THE DATE OF MAILING THEREOF. 10. FURTHER ASSURANCE; NOTICE. Debtor shall, at its expense, execute and deliver such documents and do such further acts as Secured Party may from time to time reasonably require to assure and confirm the rights created or intended to be created hereunder, to carry out the intention or facilitate the performance of the terms of the Loan Documents or to assure the validity, perfection, priority or enforceability of any security interest created hereunder. Debtor agrees to execute any instrument or instruments necessary or expedient for filing, recording, perfecting, notifying, foreclosing, and/or liquidating of Secured Party's interest in the Collateral upon request of, and as determined by, Secured Party, and Debtor hereby specifically 12 authorizes Secured Party to prepare and file Uniform Commercial Code financing statements and other documents and to execute same for and on behalf of Debtor as Debtor's attorney-in-fact, irrevocably and coupled with an interest, for such purposes. All notices required or otherwise given by either party shall be in writing and shall be delivered by hand, by registered or certified first class United States mail, return receipt requested, or by overnight courier to the other party at its address stated herein or at such other address as the other party may from time to time designate by written notice. All notices shall be deemed given when received, when delivery is refused or when returned for failure to be called for. Each provision of this Agreement shall remain in full force and effect until all of the Indebtedness is fully, finally and indefeasibly satisfied and, notwithstanding anything in this Agreement or implied by law to the contrary, the agreements of Debtor and Secured Party set forth in Sections 2(p), 2(r), 2(s), 2(t), 9 and 12 shall survive the full, final and indefeasible satisfaction of the Indebtedness. 11. JOINT AND SEVERAL OBLIGATION. If this Agreement is executed by more than one person as Debtor, each such Debtor hereby acknowledges it is jointly and severally liable for and unconditionally guarantees the prompt and full payment and performance of all obligations of each other Debtor hereunder and under the other Loan Documents. 12. WAIVER OF JURY TRIAL. DEBTOR AND SECURED PARTY HEREBY WAIVE THEIR RESPECTIVE RIGHTS TO A JURY TRIAL OF ANY CLAIM OR CAUSE OF ACTION BASED UPON OR ARISING IN CONNECTION WITH ANY OF THE LOAN DOCUMENTS. DEBTOR AND SECURED PARTY ACKNOWLEDGE THAT THIS WAIVER IS A MATERIAL INDUCEMENT TO ENTER INTO A BUSINESS RELATIONSHIP, THAT EACH HAS ALREADY RELIED ON THE WAIVER IN ENTERING INTO THE LOAN DOCUMENTS, AND THAT EACH WILL CONTINUE TO RELY ON THE WAIVER IN THEIR RELATED FUTURE DEALINGS. DEBTOR AND SECURED PARTY FURTHER WARRANT AND REPRESENT THAT EACH HAS REVIEWED THIS WAIVER WITH ITS LEGAL COUNSEL AND THAT EACH KNOWINGLY AND VOLUNTARILY WAIVES ITS JURY TRIAL RIGHTS FOLLOWING CONSULTATION WITH LEGAL COUNSEL. 13. COMPLETE AGREEMENT. The Loan Documents embody the entire agreement among the parties hereto superseding all prior commitments, agreements, representations, and understandings, whether written or oral relating to the subject matter hereof, and may not be contradicted or varied by evidence of prior, contemporaneous, or subsequent oral agreements or discussions of the parties hereto. The Loan Documents may not be altered, modified or terminated in any manner except by a writing duly signed by the parties thereto. Debtor and Secured Party intend the Loan Documents to be valid and binding and no provisions hereof and thereof which may be deemed unenforceable shall in any way invalidate any other provisions of the Loan 13 Documents, all of which shall remain in full force and effect. The Loan Documents shall be binding upon the respective successors, legal representatives, and assigns of the parties. The Schedules are incorporated herein by this reference and made a part hereof. 14. SECURITY DEPOSIT. On or before the date of this Agreement, Debtor shall cause to be deposited with Secured Party in immediately available funds the amount of One Million Three Hundred Thirty-One Thousand Four Hundred Eighty-Two and 55/100 Dollars ($1,331,482.55) (the "SECURITY DEPOSIT"), which shall be held by Secured Party as additional collateral for the due and punctual payment and performance of the Indebtedness. Debtor hereby assigns, grants and sets over to Secured Party all of Debtor's right, title, and interest in and to the Security Deposit for such purpose. For so long as the Security Deposit is held by Secured Party, the Security Deposit shall bear interest at the rate of five percent (5%) per annum, which such interest shall be paid by Secured Party to Debtor on the first business day of each consecutive calendar month beginning August 1, 1997; provided, however, that no interest shall accrue on the Security Deposit or be payable to Debtor at any time following the occurrence of an Event of Default. If (i) (a) Debtor provides evidence reasonably satisfactory to Secured Party that the Sanofi Arbitration has been fully and finally resolved (through a final, binding decision in, or settlement of, the Sanofi Arbitration), and (b) no Event of Default has occurred under Section 2(cc) above or otherwise, or (ii) if no Event of Default has occurred, at any time after July 31, 1997, then, in either case, upon Debtor's written request therefor, Secured Party shall return the Security Deposit to Debtor. IN WITNESS WHEREOF, Secured Party and Debtor have each signed this Agreement as of the day and year first above written. HELLER FINANCIAL, INC., CYGNUS, INC. a Delaware corporation a Delaware corporation By: /s/ Clifford A. Lehman By: /s/ John C. Hodgman ---------------------------- ---------------------------- Name: Clifford A. Lehman Name: John C. Hodgman ---------------------------- ---------------------------- Title: Senior Vice President Title: C.F.O. ---------------------------- ---------------------------- 14 SCHEDULE DESCRIPTION OF COLLATERAL Description of Collateral (Full description including make, model and serial number): SEE SCHEDULE A ATTACHED HERETO AND MADE A PART HEREOF. Place where Collateral is to be kept: 400 PENOBSCOT DRIVE, REDWOOD CITY, CA 94063 Other liens, encumbrances or security interests to which Collateral is or may be subject, if any: N/A Other Collateral N/A Other: If Collateral is attached or to be attached to real estate, set forth: Address of Real Estate (Including County, block number, lot number, etc.): N/A Record Owner of Real Estate (Name and Address): N/A If the real estate at which the Collateral is to be kept is leased: Name and Address of Lessor of Real Estate: N/A [ILLEGIBLE] ------------ Initials 15 SCHEDULE A PAGE 1 OF 5 Schedule annexed to and made a part of a certain Security Agreement dated the 27th day of June 1997, or related documentation by and between the undersigned. Description of Collateral (Quantity; New/Used; Model; General Description; and if applicable, Engine and/or Serial Number), together with all products and proceeds (including insurance proceeds) thereof, any, and if all increases, substitutions, replacements, attachments, additions, and accessions thereto: Asset Place-in -------------------------------------- Manufacturer Svc Date ID Description Vendor Serial Numbers Invoice # - -------- ---- ----------- ------ -------------- --------- 9/1/96 4047 COMPAQ COMPUTER NETiS Technology, Inc. 6621HXS4E058 606259 9/1/96 4048 COMPAQ COMPUTER NETiS Technology, Inc. 6621HXS4E060 606259 9/1/96 4049 COMPAQ COMPUTER NETiS Technology, Inc. 6621HXS4E614 606259 9/1/96 4050 COMPAQ COMPUTER NETiS Technology, Inc. 6621HXS4E414 606260 9/1/96 4051 COMPAQ COMPUTER NETiS Technology, Inc. 6621HXS4E048 606260 9/1/96 4052 COMPAQ COMPUTER NETiS Technology, Inc. 6621HXS4E398 606260 9/1/96 4053 HP LASERJET PRINTER A & A Technology, Inc. USBF057703 606333 9/1/96 4054 COMPAQ COMPUTER A & A Technology, Inc. S6610HXS4Q956 607315 9/1/96 4055 COMPAQ COMPUTER A & A Technology, Inc. S6610HXS4R058 607315 9/1/96 4056 COMPAQ COMPUTER A & A Technology, Inc. S6610HXS4Q881 607315 9/1/96 4057 COMPAQ COMPUTER A & A Technology, Inc. S6610HXS4Q978 607315 9/1/96 4058 COMPAQ COMPUTER A & A Technology, Inc. S6610HXS4R054 607315 9/1/96 4059 COMPAQ LAPTOP COMPUTER NETiS Technology, Inc. J626HZN7L366 607395 9/1/96 4060 COMPAQ COMPUTER A & A Technology, Inc. 6629HVT5P020 608043 9/1/96 4061 COMPAQ COMPUTER A & A Technology, Inc. 6629HVTT5P111 608043 10/1/96 4046 METTLER BALANCE SCALE WWR Scientific 54504790 10/1/96 4062 COMPAQ COMPUTER A & A Technology, Inc. 6629HVT5R254 607523 10/1/96 4067 COMPAQ COMPUTER A & A Technology, Inc. 6634HVY6U141 609258 10/1/96 4076 AUTOCAD R13 CD-ROM CAD Systems Unlimited, Inc. 19463 10/1/96 4077 EQUITY EDGE FOR VALUATION ShareData, Inc. Proposal 10/1/96 4078 VOICE MAIL SYSTEM UPGRADE Octel Communications Corp. 5026847 10/1/96 4079 DISHWASHER VWR Scientific 77288 44973100 10/1/96 4080 COMPAQ COMPUTER A & A Technology, Inc. 6629HVT5R954 607523 10/1/96 4081 COMPAQ COMPUTER A & A Technology, Inc. 6629HVT5R951 607523 11/1/96 4075 COMPAQ COMPUTER Computerland 6634HVT3Q373 3032 11/1/96 4082 COMPAQ LAPTOP COMPUTER A & A Technology, Inc. J633HZM70317 609540 11/1/96 4084 COMPAQ COMPUTER A & A Technology, Inc. 6626HVT3P195 610141 11/1/96 4085 COMPAQ COMPUTER A & A Technology, Inc. 6626HVT3P232 610141 11/1/96 4086 COMPAQ COMPUTER A & A Technology, Inc. 6626HVT3P256 610141 11/1/96 4089 COMPAQ COMPUTER A & A Technology, Inc. 6626HVT3P206 610141 11/1/96 4092 COMPAQ COMPUTER A & A Technology, Inc. 6640HVT3P146 610261 11/1/96 4093 COMPAQ COMPUTER A & A Technology, Inc. 6626HVT3P261 610141 11/1/96 4095 COMPAQ COMPUTER A & A Technology, Inc. 6626HVT3P244 610141 11/1/96 4096 COMPAQ COMPUTER A & A Technology, Inc. 6640HVT3P155 610261 PAGE 2 OF 5 Asset Place-in -------------------------------------- Manufacturer Svc Date ID Description Vendor Serial Numbers Invoice # - -------- ---- ----------- ------ -------------- --------- 11/1/96 4098 COMPAQ LAPTOP COMPUTER A & A Technology, Inc. J628HZL8P518 610503 11/1/96 4099 AUTO VESSEL ALIQUOT COLLECTOR SLR Systems, Inc. 6633BBM4P292/SG55702 Ck. Req. 11/1/96 4099 AUTO VESSEL ALIQUOT COLLECTOR SLR Systems, Inc. 6633BBM4P292/SG55702 95014 11/1/96 4099 AUTO VESSEL ALIQUOT COLLECTOR SLR Systems, Inc. 6633BBM4P292/SG55702 95019 11/1/96 4100 AUTO DIST. VESSEL ALIQ. COLLECTR SLR Systems, Inc. 6633BBM4P292/SG55702 Ck. Req. 11/1/96 4100 AUTO DIST. VESSEL ALIQ. COLLECTR SLR Systems, Inc. 6633BBM4P292/SG55702 95014 11/1/96 4100 AUTO DIST. VESSEL ALIQ. COLLECTR SLR Systems, Inc. 6633BBM4P292/SG55702 95019 11/1/96 4101 AUTO LIQUID CHROMATOGRAPHY SYS SLR Systems, Inc. 6633BBM4P292/SG55702 Ck. Req. 11/1/96 4101 AUTO LIQUID CHROMATOGRAPHY SYS SLR Systems, Inc. 6633BBM4P292/SG55702 95012 11/1/96 4101 AUTO LIQUID CHROMATOGRAPHY SYS SLR Systems, Inc. 6633BBM4P292/SG55702 95019 11/1/96 4102 CHEMDRAW PRO WIN SL CambrideSoft Corp. 24736 11/1/96 4103 MEETMAKER UPGRADE SOFTWARE On Technology Corp. 86548 11/1/96 4104 ORACLE7 WORKGROUP SERVER V7.3 Oracle Corp. 764163 12/1/96 4063 COMPAQ COMPUTER Computerland 6634HVT3Q223 2831 12/1/96 4068 COMPAQ COMPUTER Computerland 6634HVT3S281 2831 12/1/96 4069 COMPAQ LAPTOP COMPUTER Computerland J633HZM70037 3062 12/1/96 4070 COMPAQ COMPUTER Computerland 6634HVT3R360 2831 12/1/96 4072 COMPAQ LAPTOP COMPUTER Computerland J633HZM70023 3062 12/1/96 4073 COMPAQ COMPUTER Computerland 6634HVT3Q230 2831 12/1/96 4074 COMPAQ COMPUTER Computerland 6634HVT3S254 2831 12/1/96 4083 COMPAQ COMPUTER Computerland 6633HVT3Q322 3061 12/1/96 4087 COMPAQ COMPUTER Computerland 6634HVT3S300 3061 12/1/96 4088 COMPAQ COMPUTER Computerland 6634HVT3S103 3061 12/1/96 4091 COMPAQ COMPUTER Computerland 6634HVT3R355 2831 12/1/96 4094 COMPAQ COMPUTER Computerland 6634HVT3R396 3061 12/1/96 4097 COMPAQ COMPUTER NETiS Technology, Inc. 6633BBM4P292 608264 12/1/96 4105 COMPAQ COMPUTER Computerland 6640BBC3U322 10082 12/1/96 4106 COMPAQ COMPUTER Computerland 6640BBC3U105 10082 12/1/96 4107 COMPAQ COMPUTER Computerland 6640BBC3U322 10082 12/1/96 4108 COMPAQ COMPUTER Computerland 6638BBC3Q624 10082 12/1/96 4109 COMPAQ COMPUTER Computerland 6640BBC3U087 10082 12/1/96 4111 COMPAQ LAPTOP COMPUTER A & A Technology, Inc. J633HZM7031 611153 12/1/96 4112 COMPAQ COMPUTER A & A Technology, Inc. 6641HVT3Q006 610626 12/1/96 4113 COMPAQ COMPUTER A & A Technology, Inc. 6641HVT3W385 610570 12/1/96 4114 COMPAQ COMPUTER Computerland 6540BBC3U311 10082 12/1/96 4117 AUTOSAMPLER Perkin Elmer Corp. N2930010-A 10052 PAGE 3 OF 5 Asset Place-in -------------------------------------- Manufacturer Svc Date ID Description Vendor Serial Numbers Invoice # - -------- ---- ----------- ------ -------------- --------- 12/1/96 41178 AUTOSAMPLE Perkin Elmer Corp. N2930100 10052 12/1/96 4123 BINARY QA/QC SYSTEM Perkin Elmer Corp. N2600515 998687 12/1/96 4123 BINARY QA/QC SYSTEM Perkin Elmer Corp. N2600515 998408 12/1/96 4124 COMPAQ COMPUTER A & A Technology, Inc. 6637HVT3Z866 609486 12/1/96 4125 QUATERNARY PUMP Perkin Elmer Corp. N2600510 16651 12/1/96 4126 HELPSTAR FOR WINDOWS Help Desk Automation Software 3515 12/1/96 4127 COMPAQ COMPUTER Computerland 6633BBM4Q304 3180 12/1/96 4128 COMPAQ COMPUTER A & A Technology, Inc. 6641HVT3W406 610261 12/1/96 4129 COMPAQ COMPUTER A & A Technology, Inc. 6637HVT3Z183 610261 12/1/96 4130 ELECTROANALYTICAL SYSTEMS Cypress Systems 90492 12/1/96 4131 HYPERION PILLAR SYSTEM Hyperion Software N/A (Customized software) 102555 12/1/96 4131 HYPERION PILLAR SYSTEM Hyperion Software N/A (Customized software) 407375 12/1/96 4131 HYPERION PILLAR SYSTEM Hyperion Software N/A (Customized software) 311445 12/1/96 4123A TURBO-GEL PLUS SOFTWARE Avatar Consulting 1022 1/1/97 4119 COMPAQ COMPUTER Computerland 6634HVT3Q526 3061 1/1/97 4121 COMPAQ COMPUTER A & A Technology, Inc. 6644BBM4P402 611153 1/1/97 4132 COMPAQ COMPUTER A & A Technology, Inc. 6645BBC1P405 612009 1/1/97 4133 COMPAQ COMPUTER A & A Technology, Inc. 6646BBC1P720 612164 1/1/97 4135 COMPAQ COMPUTER A & A Technology, Inc. 6643BBC3R635 612009 1/1/97 4136 COMPAQ COMPUTER A & A Technology, Inc. 6643BBC3R613 612009 1/1/97 4137 COMPAQ COMPUTER A & A Technology, Inc. 6645BBC1P440 612009 1/1/97 4138 COMPAQ LAPTOP COMPUTER A & A Technology, Inc. J629HZM70812 612009 1/1/97 4140 COMPAQ COMPUTER Computerland 6629HVT3V512 3061 1/1/97 4141 WINLIMS LAB DATABASE SYSTEM Quality Systems International N/A (Customized software) 168 1/1/97 4141 WINLIMS LAB DATABASE SYSTEM Quality Systems International N/A (Customized software) 224 1/1/97 4144 COMPAQ LAPTOP COMPUTER A & A Technology, Inc. J639HZM7G990 610467 1/1/97 4145 AUTOCAD FOR PC'S R12 & R13 OBBS, Inc. 5830 1/1/97 4146 AUTOCAD FOR PC'S R12 & R13 OBBS, INC. 5830 1/1/97 4147 COMPAQ COMPUTER CompUSA 57785 1/1/97 4149 COMPAQ COMPUTER A & A Technology, Inc. 6643BBC3U242 612009 1/1/97 4150 SAMPLE CANGER - STD MODEL Gilson, Inc. 139944 1/1/97 4152 COMPAQ COMPUTER Computerland 6638BBC3Q624 10082 2/1/97 4064 100-GALLON TANK MIXER Lee Industries C367A Ck. Req. 2/1/97 4064 100-GALLON TANK MIXER Lee Industries C367A 67765 PAGE 4 OF 5 Asset Place-in -------------------------------------- Manufacturer Svc Date ID Description Vendor Serial Numbers Invoice # - -------- ---- ----------- ------ -------------- --------- 2/1/97 4064 100-GALLON TANK MIXER Lee Industries C367A 68025 2/1/97 4064 100-GALLON TANK MIXER Lee Industries C367A 68142 2/1/97 4065 LABGUARD FUME HOOD W/ CABINET ISEC Ind. 97788-14 97094053 2/1/97 4066 FLOOR SCALE Unlimited Scale of America 208828-AAA 2/1/97 4110 BECH TOP BIO-SAFETY FUME HOOD ISEC Inc. 69995ADX 96114027 2/1/97 4154 COMPAQ COMPUTER A & A Technology, Inc. 6650BBC1T612 612485 2/1/97 4155 COMPAQ COMPUTER A & A Technology, Inc. 6650BBC1T771 612485 2/1/97 4156 COMPAQ COMPUTER A & A Technology, Inc. 6650BBC1T766 612485 2/1/97 4160 COMPAQ COMPUTER A & A Technology, Inc. 6647BBC1Q717 612321 2/1/97 4161 ARTICULATED ROBOTIC SYSTEM CRS Robotics Corp. SRS-14-255A 600924 2/1/97 4162 SIGNA PLUS 8 PRINTER Computype International 1310-1042 2/1/97 4163 ONS LINE CARD Inter-Tel DataCom, Inc. 10745 2/1/97 4164 BIOCAD WKSTN & FRACTN COLLECTR PerSeptive Biosystems, Inc. 0461 117458 2/1/97 4165 STABILITY MONITORING SYSTEM Kaye Instruments, Inc. N/A (Customized software) 21278 2/1/97 4165 STABILITY MONITORING SYSTEM Kaye Instruments, Inc. N/A (Customized software) 22847 2/1/97 4165 STABILITY MONITORING SYSTEM Kaye Instruments, Inc. N/A (Customized software) 23172 3/1/97 4153 PNEUMATECH CFM DRYER K.C. Compressor Works, Inc. 0030839-IN 3/1/97 4166 DISSOLUTION SYSTEM Hanson Research Corp. 0197-0157, 0197-0170 53478 3/1/97 4167 HEADSPACE SAMPLER Perkin Elmer Corp. N6159129 52511 3/1/97 4168 AUTOSYSTEM Perkin Elmer Corp. 61N612245 47488 4/1/97 4169 COMPAQ COMPUTER NETiS Technology, Inc. 6639BBC3U388 703040 4/1/97 4170 COMPAQ COMPUTER NETiS Technology, Inc. 9947BBD2Z622 703044 4/1/97 4171 COMPAQ COMPUTER Computerland 12079 4/1/97 4172 COMPAQ COMPUTER NETiS Technology Inc. 6704BBL3D678 703112 4/1/97 4173 HP COMPUTER Computerland US64958325 12680 4/1/97 4174 HP "YODA" SERVER FOR POINTMAN InterVision Systems Tech., Inc. 374A29569 103843 4/1/97 4176 VACUUM PUMP 1/4 HP 115V Edwards High Vacuum Intern'l 972075138 475089 4/1/97 4177 POWDER MIXER CTRL SYSTEM Drivex 10070 4/1/97 4165A APPLICATION ENG. FOR #4165 Kaye Instruments, Inc. 23346 4/1/97 4175 DRAGON DICTATE POWER EDITION Safe Computing 364243 5/1/97 4189 COMPAQ COMPUTER A & A Technology, Inc. 3651BBC6054 702068 5/1/97 4190 COMPAQ COMPUTER A & A Technology, Inc. 6645BBC1Q681 702069 PAGE 5 OF 5 Asset Place-in -------------------------------------- Manufacturer Svc Date ID Description Vendor Serial Numbers Invoice # - -------- ---- ----------- ------ -------------- --------- 5/1/97 4191 HP LASERJET PRINTER Computerland SUSB5128675 12080 5/1/97 4192 COMPAQ COMPUTER A & A Technology, Inc. 6651BBL3L258 701064 5/1/97 4193 COMPAQ SERVER UPGRADE NETiS Technology, Inc. 22711106, 27280001 704385 5/1/97 4194 COMPAQ PROLIANT 2500 SERVER NETiS Technology, Inc. D78HWA349 703286 5/1/97 4195 HP COMPUTER A & A Technology, Inc. US71155712 704225 5/1/97 4197 HP LASERJET PRINTER Computerland USKB163213 13648 5/1/97 4115 BENCH TOP PRESS W/ STL DIES-1 Machine Systems, Inc. 4003-1196-1 Ck. Req. 5/1/97 4115 BENCH TOP PRESS W/ STL DIES-1 Contract Manufacturing Inc. 4003-1196-1 60006 5/1/97 4116 BENCH TOP PRESS W/ STL DIES-2 Machine Systems, Inc. 4003-1196-2 Ck. Req. 5/1/97 4116 BENCH TOP PRESS W/ STL DIES-2 Contract Manufacturing Inc. 4003-1196-1 60006 5/1/97 4181 BENCH TOP PRESS W/ SPEC TOOLING Engineering Production Eq., Inc. 4112-0297-1 Ck. Req. 5/1/97 4181 BENCH TOP PRESS W/ SPEC TOOLING Engineering Production Eq., Inc. 4112-0297-1 6155 5/1/97 4182 LAMINATOR ASSEMBLY Engineering Production Eq., Inc. 4112-0297-3 Ck. Req. 5/1/97 4182 LAMINATOR ASSEMBLY Engineering Production Eq., Inc. 4112-0297-3 6155 5/1/97 4183 HYDROGEL STRIPPING SYSTEM Engineering Production Eq., Inc. 4112-0297-4 Ck. Req. 5/1/97 4183 HYDROGEL STRIPPING SYSTEM Engineering Production Eq., Inc. 4112-0297-4 6155 5/1/97 4184 "CLAM SHELL" PRESS Engineering Production Eq., Inc. 4112-297-2 Ck. Req. 5/1/97 4184 "CLAM SHELL" PRESS Engineering Production Eq., Inc. 4112-297-2 6155 5/1/97 4196 HYDROGEN GENERATOR Whatman, Inc. 75-36 211338 5/1/97 4198 GILSON 223 SAMPLE CHANGER #1 Gilson, Inc. 158918 143940 5/1/97 4199 GILSON 223 SAMPLE CHANGER #2 Gilson, Inc. 166088 143939 PLUS: POINT MAN SOFTWARE IN CONSTRUCTION-IN-PROGRESS Point Man Software Pivotpoint, Inc. N/A Ck. Req. Point Man Software Pivotpoint, Inc. N/A 29116 Point Man Software Pivotpoint, Inc. N/A 30134 Point Man Software Pivotpoint, Inc. N/A 30403 Point Man Software Pivotpoint, Inc. N/A 30406 Point Man Software Pivotpoint, Inc. N/A 30388 HELLER FINANCIAL, INC. CYGNUS, INC. Secured Party Debtor By: /s/ Clifford A. Lehman By: /s/ John C. Hodgman ---------------------------- ---------------------------- Name: Clifford A. Lehman Name: John C. Hodgman ---------------------------- ---------------------------- Title: Senior Vice President Title: C.F.O. ---------------------------- ---------------------------- Loan No.: 1910128-0001 - ------------------------------------------------------------------------------ HELLER FINANCIAL PROMISSORY NOTE $1,331,482.55 June 30, 1997 FOR VALUE RECEIVED, CYGNUS, INC., a Delaware corporation ("Maker"), promises to pay to the order of HELLER FINANCIAL, INC., a Delaware corporation (together with any holder of this Note, "Payee"), at its office located at 500 West Monroe Street, Chicago, Illinois 60661, or at such other place as Payee may from time to time designate, the principal sum of One Million Three Hundred Thirty-One Thousand Four Hundred Eighty-Two and 55/100 Dollars ($1,331,482.55), together with interest thereon at a fixed rate equal to Nine and 39/100 percent (9.39%) per annum. Principal and interest shall be payable in thirty-six (36) consecutive monthly installments commencing August 1, 1997, and continuing on the same day of each consecutive calendar month thereafter until this Note is fully paid, each such installment in the amount of Forty-Two Thousand Five Hundred Eighty-Two and 88/100 Dollars ($42,582.88); provided, however, that in any and all events the final installment payment hereunder shall be in the amount of the entire then outstanding principal balance hereunder, plus all accrued and unpaid interest, charges and other amounts owing hereunder or under the Security Agreement (defined below). All payments shall be applied first to interest and then to principal. Interest shall be computed on the basis of a 360 day year comprised of 30-day months. Maker shall make an interest only initial payment on July 1, 1997 of accrued interest from the loan disbursement date through June 30, 1997. Notwithstanding the foregoing, if at any time implementation of any provision hereof shall cause the interest contracted for or charged herein or collectable hereunder to exceed the applicable lawful maximum rate, then the interest shall be limited to such applicable lawful maximum. This Note is secured by the collateral described in the Security Agreement dated June 27th, 1997, between Maker and Payee (the "SECURITY AGREEMENT;" and together with all related documents and instruments, the "LOAN DOCUMENTS") to which reference is made for a statement of the nature and extent of protection and security afforded, certain rights of Payee and certain rights and obligations of Maker, including Maker's rights, if any, to prepay the principal balance hereof; provided, however, that in addition to any other sum payable hereunder, under the Security Agreement or any of the other Loan Documents, in the event of a prepayment of the principal balance hereunder, whether voluntary, following acceleration or otherwise, Maker shall pay to Payee together with such prepayment a Breakage Fee (defined below), which Breakage Fee, together with the amounts payable under Section 3(ii) of the Security Agreement, if any, represents liquidated damages to Payee for the loss of its bargain and not a penalty. As used herein, the term "Breakage Fee" shall mean the amount, if any, by which (A) the present value, in the aggregate, of the then remaining installments of principal and interest due hereunder, absent the prepayment, using a discount rate equal to (i) the yield to maturity as of the date two (2) days prior to the date of the prepayment on United States Treasury securities with a final maturity approximately equal to the remaining term hereof, absent the prepayment, as published in THE WALL STREET JOURNAL, plus (ii) two and 50/100 percent (2.50%), exceeds (B) the then outstanding principal balance hereunder, absent the prepayment. Time is of the essence hereof. If payment of any installment or any other sum due under this Note or the Loan Documents is not paid when due, Maker agrees to pay a late charge equal to the lesser of (i) five cents (5CENTS) per dollar on, and in addition to, the amount of each such payment, or (ii) the maximum amount Payee is permitted to charge by law. In the event of the occurrence of an Event of Default (as defined in the Security Agreement), then the entire unpaid principal balance hereof with accrued and unpaid interest thereon, together with all other sums payable under this Note or the Loan Documents, shall, at the option of Payee and without notice or demand, become immediately due and payable, such accelerated balance bearing interest until paid at the rate of three and 00/100 percent (3.00%) per annum above the fixed rate set forth in the first paragraph of this Note. 1 Maker and all endorsers, guarantors or any others who may at any time become liable for the payment hereof hereby consent to any and all extensions of time, renewals, waivers and modifications of, and substitutions or release of security or of any party primarily or secondarily liable on, or with respect to, this Note or any of the Loan Documents or any of the terms and provisions thereof that may be made, granted or consented to by Payee, and agree that suit may be brought and maintained against any one or more of them, at the election of Payee, without joinder of the others as parties thereto, and that Payee shall not be required to first foreclose, proceed against, or exhaust any security herefor, in order to enforce payment of this Note by any one or more of them. Maker and all endorsers, guarantors or any others who may at any time become liable for the payment hereof hereby severally waive presentment, demand for payment, notice of nonpayment, protest, notice of protest, notice of dishonor, and all other notices in connection with this Note, filing of suit and diligence in collecting this Note or enforcing any of the security herefor, and, without limiting any provision of any of the Loan Documents, agree to pay, if permitted by law, all expenses incurred in collection, including reasonable attorneys' fees, and hereby waive all benefits of valuation, appraisement and exemption laws. If there be more than one Maker, all the obligations, promises, agreements and covenants of Maker under this Note are joint and several. THIS NOTE SHALL BE GOVERNED BY AND CONSTRUED IN ACCORDANCE WITH THE INTERNAL LAWS AND DECISIONS OF THE STATE OF ILLINOIS WITHOUT REGARD TO PRINCIPLES OF CONFLICTS OF LAW. AT PAYEE'S ELECTION AND WITHOUT LIMITING PAYEE'S RIGHT TO COMMENCE AN ACTION IN ANY OTHER JURISDICTION, MAKER HEREBY SUBMITS TO THE EXCLUSIVE JURISDICTION AND VENUE OF ANY COURT (FEDERAL, STATE OR LOCAL) HAVING SITUS WITHIN THE STATE OF ILLINOIS, EXPRESSLY WAIVES PERSONAL SERVICE OF PROCESS AND CONSENTS TO SERVICE BY CERTIFIED MAIL, POSTAGE PREPAID, DIRECTED TO THE LAST KNOWN ADDRESS OF MAKER, WHICH SERVICE SHALL BE DEEMED COMPLETED WITHIN TEN (10) DAYS AFTER THE DATE OF MAILING THEREOF. MAKER HEREBY WAIVES ITS RIGHTS TO A JURY TRIAL OF ANY CLAIM OR CAUSE OF ACTION BASED UPON OR ARISING OUT OF THIS NOTE. THIS WAIVER IS INFORMED AND FREELY MADE. MAKER ACKNOWLEDGES THAT THIS WAIVER IS A MATERIAL INDUCEMENT TO ENTER INTO A BUSINESS RELATIONSHIP, THAT PAYEE HAS ALREADY RELIED ON THE WAIVER IN MAKING THE LOAN EVIDENCED BY THIS NOTE, AND THAT PAYEE WILL CONTINUE TO RELY ON THE WAIVER IN ITS RELATED FUTURE DEALINGS. MAKER FURTHER WARRANTS AND REPRESENTS THAT IT HAS REVIEWED THIS WAIVER WITH ITS LEGAL COUNSEL AND THAT IT KNOWINGLY AND VOLUNTARILY WAIVES ITS JURY TRIAL RIGHTS FOLLOWING CONSULTATION WITH LEGAL COUNSEL. Witness/Attest: CYGNUS, INC. By: ------------------------------ Name: ------------------------------ Title: ------------------------------ 06/25/1997 Page 1 - ------------------------------------------------------------------------------- Cygnus - ------------------------------------------------------------------------------- Compound Period......... Monthly Nominal Annual Rate..... 9.390 % Effective Annual Rate... 9.805 % Periodic Rate........... 0.7825 % Daily Rate.............. 0.02573% CASH FLOW DATA - ------------------------------------------------------------------------------- Event Start Date Amount Number Period End Date - ------------------------------------------------------------------------------- 1 Loan 07/01/1997 1,331,482.55 1 2 Payment 08/01/1997 42,582.88 36 Monthly 07/01/2000 AMORTIZATION SCHEDULE - Normal Amortization Date Payment Interest Principal Balance - ------------------------------------------------------------------------------- Loan 07/01/1997 1,331,482.55 1997 Totals 0.00 0.00 0.00 1 08/01/1997 42,582.88 10,418.85 32,164.03 1,299,318.52 2 09/01/1997 42,582.88 10,167.17 32,415.71 1,266,902.81 3 10/01/1997 42,582.88 9,913.51 32,669.37 1,234,233.44 4 11/01/1997 42,582.88 9,657.88 32,925.00 1,201,308.44 5 12/01/1997 42,582.88 9,400.24 33,182.64 1,168,125.80 6 01/01/1998 42,582.88 9,140.58 33,442.30 1,134,683.50 7 02/01/1998 42,582.88 8,878.90 33,703.98 1,100,979.52 8 03/01/1998 42,582.88 8,615.16 33,967.72 1,067,011.80 9 04/01/1998 42,582.88 8,349.37 34,233.51 1,032,778.29 10 05/01/1998 42,582.88 8,081.49 34,501.39 998,276.90 11 06/01/1998 42,582.88 7,811.52 34,771.36 963,505.54 12 07/01/1998 42,582.88 7,539.43 35,043.45 928,462.09 1998 Totals 510,994.56 107,974.10 403,020.46 13 08/01/1998 42,582.88 7,265.22 35,317.66 893,144.43 14 09/01/1998 42,582.88 6,988.86 35,594.02 857,550.41 15 10/01/1998 42,582.88 6,710.33 35,872.55 821,677.86 16 11/01/1998 42,582.88 6,429.63 36,153.25 785,524.61 17 12/01/1998 42,582.88 6,146.73 36,436.15 749,088.46 18 01/01/1999 42,582.88 5,861.62 36,721.26 712,367.20 19 02/01/1999 42,582.88 5,574.27 37,008.61 675,358.59 20 03/01/1999 42,582.88 5,284.68 37,298.20 638,060.39 21 04/01/1999 42,582.88 4,992.82 37,590.06 600,470.33 22 05/01/1999 42,582.88 4,698.68 37,884.20 562,586.13 23 06/01/1999 42,582.88 4,402.24 38,180.64 524,405.49 24 07/01/1999 42,582.88 4,103.47 38,479.41 485,926.08 1999 Totals 510,994.56 68,458.55 442,536.01 06/25/1997 Page 2 - ------------------------------------------------------------------------------- Cygnus - ------------------------------------------------------------------------------- Date Payment Interest Principal Balance - ------------------------------------------------------------------------------- 25 08/01/1999 42,582.88 3,802.37 38,780.51 447,145.57 26 09/01/1999 42,582.88 3,498.91 39,083.97 408,061.60 27 10/01/1999 42,582.88 3,193.08 39,389.80 368,671.80 28 11/01/1999 42,582.88 2,884.86 39,698.02 328,973.78 29 12/01/1999 42,582.88 2,574.22 40,008.66 288,965.12 30 01/01/2000 42,582.88 2,261.15 40,321.73 248,643.39 31 02/01/2000 42,582.88 1,945.63 40,637.25 208,006.14 32 03/01/2000 42,582.88 1,627.65 40,955.23 167,050.91 33 04/01/2000 42,582.88 1,307.17 41,275.71 125,775.20 34 05/01/2000 42,582.88 984.19 41,598.69 84,176.51 35 06/01/2000 42,582.88 658.68 41,924.20 42,252.31 36 07/01/2000 42,582.88 330.57 42,252.31 0.00 2000 Totals 510,994.56 25,068.48 485,926.08 Grand Totals 1,532,983.68 201,501.13 1,331,482.55 06/25/1997 Page 3 - ------------------------------------------------------------------------------- Cygnus - ------------------------------------------------------------------------------- Last interest amount decreased by 0.05 due to rounding. Loan No.: 1910128-0001 - ------------------------------------------------------------------------------- HELLER FINANCIAL DELIVERY AND ACCEPTANCE CERTIFICATE TO: HELLER FINANCIAL, INC. The undersigned ("Debtor"), hereby certifies that all of the personal property described on Schedule A attached hereto, which is incorporated herein by this reference, is collateral ("Collateral") described in the Security Agreement between Heller Financial Inc. ("Secured Party") and Debtor dated June 27, 1997, ("Security Agreement"). All of the Collateral has been delivered and received .and examined and/or tested, and is in good order and operating condition and in all respects satisfactory. Debtor hereby unconditionally accepts the Collateral "AS IS." Debtor hereby acknowledges that it has reviewed and read all of the conditions and terms of the Security Agreement and hereby reaffirms and agrees to be bound by all of those terms and conditions. Debtor warrants and represents that Secured Party has a first priority perfected security interest in the Collateral under the Security Agreement and that each location of the Collateral is open, operational, and doing business. Debtor further acknowledges that it has not granted nor will it grant to any party any interest in the Collateral. Debtor further acknowledges that it has selected and specified the Collateral; SECURED PARTY HAS MADE NO REPRESENTATIONS OR WARRANTIES OF MERCHANTABILITY, FITNESS FOR PURPOSE, OR ANY OTHER REPRESENTATIONS OR WARRANTIES OF ANY KIND WHATSOEVER, EXPRESS OR IMPLIED, OR RELATING TO THE SELECTION, PURCHASE, INSTALLATION, USE, OWNERSHIP, POSSESSION, OR OPERATION OF THE COLLATERAL; that the Security Agreement is noncancellable; and that Debtor will look solely to the manufacturer/supplier of the Collateral with respect to any claims or disputes concerning the Collateral and it may not set-off or counterclaim against Secured Party or any payments due under any promissory note(s) made or given in connection with the Security Agreement. Debtor, if a corporation, hereby certifies and represents to Secured Party, that Debtor is duly authorized to execute and deliver this DELIVERY AND ACCEPTANCE CERTIFICATE and that the officers thereof signing on its behalf are duly authorized to execute and deliver same. This certificate will supplement and not alter the terms of the Security Agreement and is given to induce Secured Party to finance the Collateral. CYGNUS, INC. By: /s/ John C. Hodgman -------------------------- Name: John C. Hodgman -------------------------- Title: C.F.O. -------------------------- Date: 6/27/97 -------------------------- Witness/Attest: [ILLEGIBLE] -------------------------- (Corporate Seal) [ILLEGIBLE] SCHEDULE A PAGE 1 OF 5 Schedule annexed to and made a part of a certain Security Agreement dated the 27th day of June 1997, or related documentation. Description of Collateral (Quantity; New/Used; Model; General Description; and if applicable. Engine and/or Serial Number), together with all products and proceeds (including insurance proceeds) thereof, any, and if all increases, substitutions, replacements, attachments, additions, and accessions thereto. ASSET PLACE-IN ------------------------------------------ MANUFACTURER SYC DATE ID DESCRIPTION VENDOR SERIAL NUMBERS INVOICE # - -------- ---- ----------- ------ -------------- --------- 9/1/96 4047 COMPAQ COMPUTER NETiS Technology, Inc. 6621HXS4E058 606259 9/1/96 4048 COMPAQ COMPUTER NETiS Technology, Inc. 6621HXS4E060 606259 9/1/96 4049 COMPAQ COMPUTER NETiS Technology, Inc. 6621HXS4E614 606259 9/1/96 4050 COMPAQ COMPUTER NETiS Technology, Inc. 6621HXS4E414 606260 9/1/96 4051 COMPAQ COMPUTER NETiS Technology, Inc. 6621HXS4E048 506260 9/1/96 4052 COMPAQ COMPUTER NETiS Technology, Inc. 6621HSX4E398 606260 9/1/96 4053 HP LASERJET PRINTER A & A Technology, Inc. USBF057703 606333 9/1/96 4054 COMPAQ COMPUTER A & A Technology, Inc. S6610HXS4Q956 507315 9/1/96 4055 COMPAQ COMPUTER A & A Technology, Inc. S6610HXS4R058 607315 9/1/96 4056 COMPAQ COMPUTER A & A Technology, Inc. S6610HXS4Q881 607315 9/1/96 4057 COMPAQ COMPUTER A & A Technology, Inc. S6610HXS4Q978 607315 9/1/96 4058 COMPAQ COMPUTER A & A Technology, Inc. S6610HXS4R054 607315 9/1/96 4059 COMPAQ LAPTOP COMPUTER NETiS Technology, Inc. J626HZN7L366 607395 9/1/96 4060 COMPAQ COMPUTER A & A Technology, Inc. 6629HVT5P020 608043 9/1/96 4061 COMPAQ COMPUTER A & A Technology, Inc. 6629HVTT5P111 608043 10/1/96 4046 METTLER BALANCE SCALE VWR Scientific 54504790 10/1/96 4062 COMPAQ COMPUTER A & A Technology, Inc. 6629HVT5R254 607523 10/1/96 4067 COMPAQ COMPUTER A & A Technology, Inc. 6634HVY6U141 609258 10/1/96 4076 AUTOCAD R13 CD-ROM CAD Systems Unlimited, Inc. 19463 10/1/96 4077 EQUITY EDGE FOR VALUATION ShareData, Inc. Proposal 10/1/96 4078 VOICE MAIL SYSTEM UPGRADE Octel Communications Corp. 5025847 10/1/96 4079 DISHWASHER VWR Scientific 77288 44973100 10/1/96 4080 COMPAQ COMPUTER A & A Technology, Inc. 6629HVTSR954 507523 10/1/96 4081 COMPAQ COMPUTER A & A Technology, Inc. 6629HVT5R951 507523 11/1/96 4075 COMPAQ COMPUTER Computerland 5634HVT3Q373 3032 11/1/96 4082 COMPAQ LAPTOP COMPUTER A & A Technology, Inc. J633HZW70317 609540 11/1/96 4084 COMPAQ COMPUTER A & A Technology, Inc. 6626HVT3P195 610141 11/1/96 4085 COMPAQ COMPUTER A & A Technology, Inc. 6626HVT3P232 610141 11/1/96 4086 COMPAQ COMPUTER A & A Technology, Inc. 6626HVT3P256 610141 11/1/96 4089 COMPAQ COMPUTER A & A Technology, Inc. 6625HVT3P206 610141 11/1/96 4092 COMPAQ COMPUTER A & A Technology, Inc. 6640HVT3P146 601251 11/1/96 4093 COMPAQ COMPUTER A & A Technology, Inc. 6626HVT3P261 610141 11/1/96 4095 COMPAQ COMPUTER A & A Technology, Inc. 6626HVT3P244 610141 11/1/96 4096 COMPAQ COMPUTER A & A Technology, Inc. 6840HVT3P155 610261 SCHEDULE A Page 2 of 5 ASSET PLACE-IN ------------------------------------------ MANUFACTURER SYC DATE ID DESCRIPTION VENDOR SERIAL NUMBERS INVOICE # - -------- ---- ----------- ------ -------------- --------- 11/1/96 4098 COMPAQ LAPTOP COMPUTER A & A Technology, Inc. J628HZL8P518 610503 11/1/96 4099 AUTO VESSEL ALIQUOT COLLECTOR SLR Systems, Inc. 6633BBM4P292/SG55702 Ck Req. 11/1/96 4099 AUTO VESSEL ALIQUOT COLLECTOR SLR Systems, Inc. 6633BBM4P292/SG55702 95014 11/1/96 4099 AUTO VESSEL ALIQUOT COLLECTOR SLR Systems, Inc. 6633BBM4P292/SG55702 95019 11/1/96 4100 AUTO VESSEL ALIQUOT COLLECTOR SLR Systems, Inc. 6633BBM4P292/SG55702 Ck Req. 11/1/96 4100 AUTO VESSEL ALIQUOT COLLECTOR SLR Systems, Inc. 6633BBM4P292/SG55702 95014 11/1/96 4100 AUTO VESSEL ALIQUOT COLLECTOR SLR Systems, Inc. 6633BBM4P292/SG55702 95019 11/1/96 4101 AUTO LIQUID CHROMATOGRAPHY SYS SLR Systems, Inc. 6633BBM4P292/SG55702 Ck Req. 11/1/96 4101 AUTO LIQUID CHROMATOGRAPHY SYS SLR Systems, Inc. 6633BBM4P292/SG55702 95012 11/1/96 4101 AUTO LIQUID CHROMATOGRAPHY SYS SLR Systems, Inc. 6633BBM4P292/SG55702 95019 11/1/96 4102 CHEMDRAW PRO WIN SL CambrigeSoft Corp. 24736 11/1/96 4103 MEETMAKER UPGRADE SOFTWARE OnTechnology Corp. 86548 11/1/96 4104 ORACLE7 WORKGROUP SERVER V7.3 Oracle Corp. 764153 12/1/96 4063 COMPAQ COMPUTER Computerland 6634HVT3Q223 2831 12/1/96 4068 COMPAQ COMPUTER Computerland 6634HVT3S281 2831 12/1/96 4069 COMPAQ LAPTOP COMPUTER Computerland 6633HZM70037 3062 12/1/96 4070 COMPAQ COMPUTER Computerland 6634HVT3R360 2831 12/1/96 4072 COMPAQ LAPTOP COMPUTER Computerland J633HZM70023 3062 12/1/96 4073 COMPAQ COMPUTER Computerland 6634HVT3Q230 2831 12/1/96 4074 COMPAQ COMPUTER Computerland 6634HVT3S254 2831 12/1/96 4083 COMPAQ COMPUTER Computerland 6633HVT3Q322 3061 12/1/96 4087 COMPAQ COMPUTER Computerland 6634HVT3S300 3061 12/1/96 4088 COMPAQ COMPUTER Computerland 6634HVT3S103 3061 12/1/96 4091 COMPAQ COMPUTER Computerland 6634HVT3R366 2831 12/1/96 4094 COMPAQ COMPUTER Computerland 6634HVT3R398 3061 12/1/96 4097 COMPAQ COMPUTER NETiS Technology, Inc. 6633BBM4P292 608264 12/1/96 4105 COMPAQ COMPUTER Computerland 6640BBC3U322 10082 12/1/96 4106 COMPAQ COMPUTER Computerland 6640BBC3U105 10082 12/1/96 4107 COMPAQ COMPUTER Computerland 6640BBC3U322 10082 12/1/96 4108 COMPAQ COMPUTER Computerland 6638BBC3Q624 10082 12/1/96 4109 COMPAQ COMPUTER Computerland 6640BBC3U087 10082 12/1/96 4111 COMPAQ LAPTOP COMPUTER A & A Technology, Inc. J633HZM7031 611153 12/1/96 4112 COMPAQ COMPUTER A & A Technology, Inc. 6641HVT3Q006 610626 12/1/96 4113 COMPAQ COMPUTER A & A Technology, Inc. 6641HVT3W385 610570 12/1/96 4114 COMPAQ COMPUTER Computerland 6640BBC3U311 10082 12/1/96 4117 AUTOSAMPLER Perkin Elmer Corp. N2930010-A 10052 SCHEDULE A Page 3 of 5 ASSET PLACE-IN ------------------------------------------ MANUFACTURER SYC DATE ID DESCRIPTION VENDOR SERIAL NUMBERS INVOICE # - -------- ---- ----------- ------ -------------- --------- 12/1/96 4118 AUTOSAMPLER Perkin Elmer Corp. N2930100 10052 12/1/96 4123 BINARY QA/QC SYSTEM Perkin Elmer Corp. N2600515 998687 12/1/96 4123 BINARY QA/QC SYSTEM Perkin Elmer Corp. N2600515 998408 12/1/96 4124 COMPAQ COMPUTER A & A Technology, Inc. 6637HVT3Z866 609486 12/1/96 4125 QUATERNARY PUMP Perkin Elmer Corp. N2600510 16651 12/1/96 4126 HELPSTAR FOR WINDOWS Help Desk Automation Software 3515 12/1/96 4127 COMPAQ COMPUTER Computerland 6633BBM4Q304 3180 12/1/96 4128 COMPAQ COMPUTER A & A Technology, Inc. 6641HVT3W406 610261 12/1/96 4129 COMPAQ COMPUTER A & A Technology, Inc. 6637HVT3Z193 610261 12/1/96 4130 ELECTROANALYTICAL SYSTEMS Cypress Systems 90492 12/1/96 4131 HYPERION PILLAR SYSTEM Hyperion Software N/A (Customized software) 102555 12/1/96 4131 HYPERION PILLAR SYSTEM Hyperion Software N/A (Customized software) 407375 12/1/96 4131 HYPERION PILLAR SYSTEM Hyperion Software N/A (Customized software) 311445 12/1/96 4123A TURBO-GEL PLUS SOFTWARE Avatar Consulting 1022 1/1/97 4119 COMPAQ COMPUTER Computerland 6634HVT3Q526 3061 1/1/97 4121 COMPAQ COMPUTER A & A Technology, Inc. 6644BBM4P402 611153 1/1/97 4132 COMPAQ COMPUTER A & A Technology, Inc. 6645BBC1P405 612009 1/1/97 4133 COMPAQ COMPUTER A & A Technology, Inc. 6646BBC1P720 612164 1/1/97 4135 COMPAQ COMPUTER A & A Technology, Inc. 6643BBC3R635 612009 1/1/97 4136 COMPAQ COMPUTER A & A Technology, Inc. 6643BBC3R613 612009 1/1/97 4137 COMPAQ COMPUTER A & A Technology, Inc. 6645BBC1P440 612009 1/1/97 4138 COMPAQ LAPTOP COMPUTER A & A Technology, Inc. J629HZM70812 612009 1/1/97 4140 COMPAQ COMPUTER Computerland 6629HVT3V512 3061 1/1/97 4141 WINLIMS LAB DATABASE SYSTEM Quality Systems International N/A (Customer software) 168 1/1/97 4141 WINLIMS LAB DATABASE SYSTEM Quality Systems International N/A (Customer software) 224 1/1/97 4144 COMPAQ LAPTOP COMPUTER A & A Technology, Inc. J639HZM7G990 610467 1/1/97 4145 AUTOCAD FOR PC'S R12 & R13 OBBS, Inc. 5830 1/1/97 4146 AUTOCAD FOR PC'S R12 & R13 OBBS, Inc. 5830 1/1/97 4147 COMPAQ COMPUTER CompUSA 57785 1/1/97 4149 COMPAQ COMPUTER A & A Technology, Inc. 6643BBC3U242 612009 1/1/97 4150 SAMPLE CANGER - STD MODEL Gilson, Inc. 139944 1/1/ 97 4152 COMPAQ COMPUTER Computerland 6638BBC3Q624 10082 2/1/97 4064 100-GALLON TANK MIXER Lee Industries C367A Ck Req. 2/1/97 4064 100-GALLON TANK MIXER Lee Industries C367A 67755 SCHEDULE A Page 4 of 5 ASSET PLACE-IN ------------------------------------------ MANUFACTURER SYC DATE ID DESCRIPTION VENDOR SERIAL NUMBERS INVOICE # - -------- ---- ----------- ------ -------------- --------- 2/1/97 4064 100-GALLON TANK MIXER Lee Industries C367A 68025 2/1/97 4064 100-GALLON TANK MIXER Lee Industries C367A 68142 2/1/97 4065 LABGUARD FUME HOOD W/CABINET ISEC Inc. 97788-14 97094053 2/1/97 4066 FLOOR SCALE Unlimited Scale of America 208828-AAA 2/1/97 4110 BECH TOP BIO-SAFETY FUME HOOD ISEC Inc. 69995ADX 96114027 2/1/97 4154 COMPAQ COMPUTER A & A Technology, Inc. 6650BBC1T612 612485 2/1/97 4155 COMPAQ COMPUTER A & A Technology, Inc. 6650BBC1T771 612485 2/1/97 4156 COMPAQ COMPUTER A & A Technology, Inc. 6650BBC1T766 612485 2/1/97 4160 COMPAQ COMPUTER A & A Technology, Inc. 6647BBC1Q717 612321 2/1/97 4161 ARTICULATED ROBOTIC SYSTEM CRS Robotics Corp SRS-14-255A 600924 2/1/97 4162 SIGMA PLUS 8 PRINTER Computype International 1310-1042 2/1/97 4163 ONS LINE CARD Inter-Tel DataCom, Inc 10754 2/1/97 4164 BIOCAD WKSTN & FRACTN COLLECTR PerSeptive Biosystems, Inc 0461 117458 2/1/97 4165 STABILITY MONITORING SYSTEM Kaye Instruments, Inc N/A (Customized software) 21278 2/1/97 4165 STABILITY MONITORING SYSTEM Kaye Instruments, Inc N/A (Customized software) 22847 2/1/97 4165 STABILITY MONITORING SYSTEM Kaye Instruments, Inc N/A (Customized software) 23172 3/1/97 4153 PNEUMATECH CFM DRYER K.C. Compressor Works, Inc. 0030839-IN 3/1/97 4166 DISSOLUTION SYSTEM Hanson Research Corp 0197-0157, 0197-0170 53478 3/1/97 4167 HEADSPACE SAMPLER Perkin Elmer Corp. N6159129 52511 3/1/97 4168 AUTOSYSTEM Perkin Elmer Corp. 61N612245 47488 4/1/97 4169 COMPAQ COMPUTER NETiS Technology, Inc. 6639BBC3U388 703040 4/1/97 4170 COMPAQ COMPUTER NETiS Technology, Inc. 9947BBD2Z622 703044 4/1/97 4171 COMPAQ COMPUTER Computerland 12079 4/1/97 4172 COMPAQ COMPUTER NETiS Technology, Inc. 6704BBL3D878 703112 4/1/97 4173 HP COMPUTER Computerland US64958325 12680 4/1/97 4174 HP "YCDA" SERVER FOR POINTMAN InterVision Systems Tech, Inc. 374A29569 103843 4/1/97 4176 VACUUM PUMP 1/4 HP 115V Edwards High Vacuum Intern'l 972075138 475089 4/1/97 4177 POWDER MIXER CTRL SYSTEM Drivex 10070 4/1/97 4165A APPLICATION ENG. FOR #4165 Kaye Instruments, Inc 23346 4/1/97 4175 DRAGON DICTATE POWER EDITION Safe Computing 364243 5/1/97 4189 COMPAQ COMPUTER A & A Technology, Inc. 3651BBC16054 702068 5/1/97 4190 COMPAQ COMPUTER A & A Technology, Inc. 6645BBC1Q681 702069 SCHEDULE A Page 5 of 5 ASSET PLACE-IN ------------------------------------------ MANUFACTURER SYC DATE ID DESCRIPTION VENDOR SERIAL NUMBERS INVOICE # - -------- ---- ----------- ------ -------------- --------- 5/1/97 4191 HP LASERJET PRINTER Computerland SUSB5128675 12080 5/1/97 4192 COMPAQ COMPUTER A & A Technology, Inc. 6651BBL3U258 701054 5/1/97 4193 COMPAQ SERVER UPGRADE NETiS Technology, Inc. 2711106, 27280001 704385 5/1/97 4194 COMPAQ PROLIANT 250C SERVER NETiS Technology, Inc. D78HWA349 703286 5/1/97 4195 HP COMPUTER A & A Technology, Inc. JS71155712 704225 5/1/97 4197 HP LASERJET PRINTER Computerland LSKB163213 13648 5/1/97 4115 BENCH TOP PRESS W/STL DIES-1 Machine Systems, Inc. 4003-1196-1 Ck Req 5/1/97 4115 BENCH TOP PRESS W/STL DIES-1 Contract Manufacturing Inc. 4003-1196-1 60006 5/1/97 4116 BENCH TOP PRESS W/STL DIES-2 Machine Systems, Inc. 4003-1196-2 Ck Req 5/1/97 4116 BENCH TOP PRESS W/STL DIES-2 Contract Manufacturing Inc. 4003-1196-2 60006 5/1/97 4181 BENCH TOP PRESS W/SPEC TOOLING Engineering Production Eq., Inc. 4112-0297-1 Ck Req 5/1/97 4181 BENCH TOP PRESS W/SPEC TOOLING Engineering Production Eq., Inc. 4112-0297-1 6155 5/1/97 4182 LAMINATOR ASSEMBLY Engineering Production Eq., Inc. 4112-0297-3 Ck Req 5/1/97 4182 LAMINATOR ASSEMBLY Engineering Production Eq., Inc. 4112-0297-3 6155 5/1/97 4183 HYDROGEL STRIPPING SYSTEM Engineering Production Eq., Inc. 4112-0297-4 Ck Req 5/1/97 4183 HYDROGEL STRIPPING SYSTEM Engineering Production Eq., Inc. 4112-0297-4 6155 5/1/97 4184 "CLAM SHELL" PRESS Engineering Production Eq., Inc. 4112-297-2 Ck Req 5/1/97 4184 "CLAM SHELL" PRESS Engineering Production Eq., Inc. 4112-297-2 6155 5/1/97 4196 HYDROGEN GENERATOR Whatman, Inc 75-36 211338 5/1/97 4198 GILSON 223 SAMPLE CHANGER #1 Gilson, Inc. 158918 143940 5/1/97 4199 GILSON 223 SAMPLER CHANGER #2 Gilson, Inc. 166088 143939 PLUS: POINT MAN SOFTWARE IN CONSTRUCTION-IN-PROGRESS Point Man Software Pivotpoint, Inc. N/A Ck Req Point Man Software Pivotpoint, Inc. N/A 29116 Point Man Software Pivotpoint, Inc. N/A 30134 Point Man Software Pivotpoint, Inc. N/A 30403 Point Man Software Pivotpoint, Inc. N/A 30406 Point Man Software Pivotpoint, Inc. N/A 30388 PROCEEDS REQUEST AND INSTRUCTIONS LETTER June 24, 1997 Heller Financial, Inc. 500 West Monroe Chicago, IL 60661 Attention: Commercial Equipment Finance Division RE: CYGNUS, INC. ("BORROWER") Gentlemen: In connection with the Security Agreement dated June 27, 1997, by and between Heller Financial, Inc. ("Heller"), and Borrower ("Agreement"), Borrower hereby requests a loan in the principal amount of One Million Three Hundred Thirty-One Thousand Four Hundred Eighty-Two and 55/100 Dollars ($1,331,482.55) (the "Advance"). Borrower hereby authorizes and directs Heller to disburse the Advance, on Borrower's behalf, to the following entities by check or wire transfer according to the following instructions: a. Cygnus, Inc. $1,331,482.55 400 Penobscot Drive Redwood City, CA 94063 Borrower agrees that for purposes of the Agreement and all documents and instruments related thereto, the Advance shall be deemed to have paid to Borrower immediately upon its disbursement in accordance with the foregoing instructions, notwithstanding that the receipt of all or any part of the Advance by any intended recipient may be delayed by mail or other factors. Cordially, CYGNUS, INC. a Delaware corporation By: /s/ John C. Hodgman ------------------------- Name: John C. Hodgman ------------------------- Title: C.F.O. ------------------------- Date: 6/27/97 ------------------------- 1 PAGE 1 STATE OF DELAWARE OFFICE OF THE SECRETARY OF STATE -------------------------------- I, EDWARD J. FREEL, SECRETARY OF STATE OF THE STATE OF DELAWARE, DO HEREBY CERTIFY THE ATTACHED IS A TRUE AND CORRECT COPY OF THE RESTATED CERTIFICATE OF "CYGNUS, INC.", FILED IN THIS OFFICE ON THE FIFTH DAY OF OCTOBER, A.D. 1995, AT 9 0'CLOCK A.M. A CERTIFIED COPY OF THIS CERTIFICATE HAS BEEN FORWARDED TO THE KENT COUNTY RECORDER OF DEEDS FOR RECORDING. [SEAL OF STATE OF DELAWARE] /s/ Edward J. Freel [SECRETARY'S SEAL] --------------------------------------- EDWARD J. FREEL, SECRETARY OF STATE AUTHENTICATION: 7667280 DATE: 10-06-95 AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF CYGNUS, INC. CYGNUS, INC., a corporation organized and existing under the General Corporation Law of the State of Delaware DOES HEREBY CERTIFY: FIRST: The original Certificate of Incorporation of CYGNUS, INC. was filed with the Secretary of State of Delaware on March 15, 1994. SECOND: The Amended and Restated Certificate of Incorporation of CYGNUS, INC. has been duly adopted in accordance with the provisions of Sections 245 and 242 of the General Corporation Law of the State of Delaware by the directors of the Corporation and such Amended and Restated Certificate of Incorporation shall be amended and restated to read in full as follows: I. The name of the corporation is CYGNUS, INC. (the "Corporation"). II. The address of the Corporation's registered office in the State of Delaware is 32 Loockerman Square, Suite L-100, City of Dover, County of Kent and the name of its registered agent at such address is The Prentice-Hall Corporation System, Inc. III. The purpose of the Corporation is to engage in any lawful act or activity for which corporations may be organized under the General Corporation Law of Delaware. IV. The Corporation is authorized to issue two classes of shares to be designated respectively Common Stock and Preferred Stock. The total number of shares of all classes of stock which the Corporation has authority to issue is Thirty-Five Million (35,000,000) shares, consisting of Thirty Million (30,000,000) shares of Common Stock, each having a par value of one-tenth of one cent ($.001) (the "Common Stock") and Five Million (5,000,000) shares of Preferred Stock, each having a par value of one-tenth of one cent ($.001) (the "Preferred Stock"). 1 As to the Preferred Stock of the Corporation, the Board of Directors shall have the power to issue any additional shares of Preferred Stock from time to time in one or more series. The Board of Directors is hereby authorized to fix or alter from time to time the voting powers and such designations, preferences and relative, participating, optional or other special rights of the shares of each such series and the qualifications, limitations or restrictions of any wholly unissued series of Preferred Stock, and to establish from time to time the number of shares constituting any such series, or any of them. The Board of Directors is further authorized to increase or decrease (but not below the number of shares of any such series then outstanding) the number of shares of any series, the number of which was fixed by it, subsequent to the issue of shares of such series then outstanding, subject to the limitations and restrictions stated in the resolution of the Board of Directors originally fixing the number of shares of such series. If the number of shares of any series is so decreased, then the shares constituting such decrease shall resume the status which they had prior to the adoption of the resolution originally fixing the number of shares of such series. V. The Corporation is to have perpetual existence. VI. The election of directors need not be by written ballot unless the Bylaws of the Corporation shall so provide. VII. The number of directors which constitute the whole Board of Directors of the Corporation shall be designated in the Bylaws of the Corporation. Subject to the rights of the holders of any series of Preferred Stock, no director shall be removed without cause. Subject to any limitations imposed by law, the Board of Directors or any individual director may be removed from office at any time with cause by the affirmative vote of the holders of a majority of the voting power of all the then-outstanding shares of voting stock of the Corporation entitled to vote at the election of directors. VIII. In furtherance and not in limitation of the powers conferred by statute, the Board of Directors is expressly authorized to make, alter, amend or repeal the Bylaws of the Corporation. Subject to Section 6.1 of the Bylaws, the Bylaws may also be altered or amended or new Bylaws adopted by the affirmative vote of least two-thirds (2/3) of the combined voting power of all the then-outstanding shares of the Corporation entitled to vote. 2 IX. To the fullest extent permitted by the Delaware General Corporation Law as the same exists or as may hereafter be amended, no director of the Corporation shall be personally liable to the Corporation or its stockholders for monetary damages for breach of fiduciary duty as a director. Neither any amendment nor repeal of this Article, nor the adoption of any provision of this Certificate of Incorporation inconsistent with this Article, shall eliminate or reduce the effect of this Article in respect of any matter occurring, or any cause of action, suit or claim that, but for this Article, would accrue or arise, prior to such amendment, repeal or adoption of an inconsistent provision. X. Each director shall serve until his or her successor is duly elected and qualified or until his or her death, resignation or removal. No decrease in the number of directors constituting the Board of Directors shall shorten the term of any incumbent director. No stockholder will be permitted to cumulate votes at any election of directors. Subject to the rights of the holders of any series of Preferred Stock, any vacancies on the Board of Directors resulting from death, resignation, disqualification, removal or other causes, and any newly created directorships resulting from any increase in the number of directors, shall, unless the Board of Directors determines by resolution that any such vacancies or newly created directorships shall be filled by the stockholders, except as otherwise provided by law, be filled only by the affirmative vote of a majority of the directors then in office, even though less than a quorum of the Board of Directors, and not by the stockholders. Any director elected in accordance with the preceding sentence shall hold office for the remainder of the full term of the director for which the vacancy was created or occurred and until such director's successor shall have been elected and qualified. XI. Meetings of stockholders may be held within or without the State of Delaware, as the Bylaws may provide. The books of the Corporation may be kept (subject to any provision contained in the statutes) outside of the State of Delaware at such place or places as may be designated from time to time by the Board of Directors or in the Bylaws of the Corporation. XII. No action shall be taken by the stockholders of the Corporation except at an annual or special meeting of stockholders called in accordance with the Bylaws and no action shall be taken by the stockholders by written consent in lieu of a meeting. 3 XIII. Notwithstanding any other provisions of this Certificate of Incorporation or any provision of law which might otherwise permit a lesser vote or no vote, but in addition to any affirmative vote of the holders of the capital stock required by law or this Certificate of Incorporation, the affirmative vote of the holders of at least two-thirds (2/3) of the combined voting power of all of the then-outstanding shares of the Corporation entitled to vote shall be required to alter, amend or repeal Articles VI, VII, VIII, IX, X, XI, XII, XIII or any provision thereof. 4 XIV. The Corporation reserves the right to amend, alter, change or repeal any provision contained in this Certificate of Incorporation, in the manner now or hereafter prescribed by statute, except as provided in Article XIII, and all rights conferred upon stockholders herein are granted subject to this reservation. The undersigned incorporator hereby acknowledges that the foregoing Certificate of Incorporation is his act and deed and that the facts stated herein are true. /s/ Gregory B. Lawless --------------------------------------- Gregory B. Lawless President, Chief Executive Officer and Director Dated: October 4, 1995 5