SECOND AMENDMENT TO THE EXECUTIVE EMPLOYMENT
                    AGREEMENT AND GENERAL AND SPECIAL RELEASE


          This Second Amendment to the Executive Employment Agreement and 
General and Special Release (this "Second Amendment and Release") is entered 
into as of this 30th day of May, 1997, by and between ALEXANDRIA REAL ESTATE 
EQUITIES, INC., a Maryland corporation (formerly known as Health Science 
Properties, Inc.) (the "Corporation"), and JERRY M. SUDARSKY, an individual 
(the "Officer") (collectively, the "Parties").

          WHEREAS, Officer originally entered into that certain Executive 
Employment Agreement (the "Employment Agreement"), dated as of June 9, 1994, 
with Health Science Properties Holding Corporation (the "Parent"), and on 
November 3, 1994, Parent transferred to the Corporation substantially all of 
its property, assets and certain liabilities, including Parent's rights and 
obligations under the Employment Agreement;

          WHEREAS, on July 30, 1996, the Parties amended the Employment 
Agreement by execution of that certain First Amendment to the Employment 
Agreement Between Health Science Properties, Inc. And Jerry M. Sudarsky, 
pursuant to which the Corporation agreed to employ Officer as its Chairman of 
the Board of Directors (the "Chairman") and Chief Executive Officer until 
December 31, 2000;

          WHEREAS, on March 14, 1997, Officer resigned from the position of 
Chief Executive Officer of the Corporation and currently serves as full-time 
executive Chairman of the Corporation; and

          WHEREAS, upon consummation of an initial public offering by the 
Corporation of its common stock (the "IPO"), Officer desires to retire from 
employment with the Corporation and thereafter to serve as non-executive 
Chairman of the Corporation and perform the duties consistent with such 
position for the duration of his term as Chairman, which expires at the next 
annual election of officers.

          NOW, THEREFORE, in consideration of the mutual covenants and 
agreements contained herein, and for good and valuable consideration, the 
receipt and sufficiency of which are hereby acknowledged, the Parties hereto 
agree as follows:



          1.   AMENDMENTS TO EMPLOYMENT AGREEMENT.

               a. OFFICER'S RETIREMENT; TERMINATION OF EMPLOYMENT AGREEMENT. 
Effective upon consummation of the IPO, Officer shall voluntarily retire from 
employment with the Corporation.  Except as expressly provided herein, all of 
the Corporation's duties and obligations under the Employment Agreement shall 
terminate effective as of the date of Officer's retirement.  Officer 
acknowledges and agrees that his voluntary retirement pursuant to this Second 
Amendment and Release is not, and shall not be treated as, a Termination for 
Good Reason pursuant to Section 4.2 of the Employment Agreement.

               b. RETIREMENT BENEFITS.  Section 3.5(e) of the Employment 
Agreement is hereby amended in its entirety to read as follows:  

     "(e) RETIREMENT BENEFIT.  Commencing on the date of consummation of the 
     IPO, the Company shall pay Officer an annual retirement benefit equal to 
     One Hundred Fifty Thousand Dollars ($150,000) per year for a period of 
     three (3) years, and, thereafter, shall pay Officer an annual retirement 
     benefit equal to Ninety Thousand Dollars ($90,000) per year as provided 
     herein; PROVIDED, HOWEVER, that commencing June 1 of the year following 
     the year in which the retirement benefit is reduced to Ninety Thousand 
     Dollars ($90,000) per year, the amount of the retirement benefit shall 
     be increased by 2% per year on June 1 of each year thereafter.  The 
     benefit shall be payable monthly, beginning on the first day of the 
     month following the month in which consummation of the IPO occurs and 
     shall be payable in the form of a 100% joint and survivor annuity on the 
     lives of Officer and Officer's spouse as of the date hereof, if then 
     living; PROVIDED, HOWEVER that in the event of a Change in Control (as 
     defined in Section 4.4(d) of this  Employment Agreement), the 
     Corporation shall secure the payment of such benefit through the 
     purchase of an annuity contract that provides Officer with the benefit 
     described in this Paragraph 3.5(e).   In the event of Officer's death 
     prior to the commencement of the retirement benefit under this Paragraph 
     3.5(e), Officer's spouse as of the date hereof, if then living, shall be 
     entitled to receive, commencing on the first day of the month next 
     following Officer's death, the retirement benefit, the Officer's spouse 
     as of the date hereof, would have received had Officer retired and 
     commenced receiving benefits immediately prior to his death. Amounts 
     payable under this Paragraph 3.5(e) shall be offset by any amounts paid 
     to Officer under any Disability Policy maintained by the Corporation."

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               c.  SURVIVAL OF PROVISIONS.  Notwithstanding the termination 
of the Employment Agreement pursuant to Section 1(a), above, the rights and 
obligations of the Parties with respect to Sections 3.5(e) (as amended in 
Section 1(b), above), 5, 6.1, 6.2, 6.3, 6.8, 6.10, 6.11, and 6.13 of the 
Employment Agreement shall survive the termination of that agreement.

          2.   STATUS AS CHAIRMAN OF THE BOARD OF DIRECTORS.  The execution 
of this Second Amendment and Release shall not preclude Officer from serving 
as, and the Corporation hereby acknowledges that it intends to continue to 
retain Officer as, non-executive Chairman performing the duties consistent 
with such position at least for the remainder of his term as Chairman, which 
expires at the next annual election of officers.

          3.   RELEASE OF CLAIMS AND OTHER MATTERS.

               a.   OFFICER'S GENERAL AND SPECIAL RELEASE. In consideration 
of the benefits provided to Officer pursuant to this Second Amendment and 
Release, Officer hereby forever releases and discharges the Corporation, its 
parent, subsidiary and affiliated corporations, and each of their respective 
present and former officers, directors, managers, agents, employees, and 
attorneys, and their successors and assigns (collectively, the "Released 
Parties") from any and all claims, charges, complaints, liens, demands, 
causes of action, obligations, damages and liabilities, KNOWN OR UNKNOWN, 
SUSPECTED OR UNSUSPECTED, that Officer had, now has, or may hereafter claim 
to have against the Released Parties, arising out of or relating in any way 
to Officer's employment with or his separation from the Corporation, any and 
all alleged acts or omissions of any of the Released Parties, and any other 
claim relating to any of the Released Parties from the beginning of time 
through the effective date of Officer's resignation from the Corporation 
pursuant to Section 1(a), above.  This release specifically extends to, 
without limitation, claims or causes of action for wrongful termination, 
impairment of ability to compete in the open labor market, breach of an 
express or implied contract, breach of the covenant of good faith and fair 
dealing, breach of fiduciary duty, fraud, misrepresentation, defamation, 
slander, infliction of emotional distress, disability, loss of future 
earnings, and claims under the California Constitution, the United States 
Constitution, and applicable state and federal fair employment laws, federal 
equal employment opportunity laws, and federal and state labor statutes and 
regulations, including, but not limited to, the Civil Rights Act of 1964, as 
amended, the Fair Labor Standards Act, as amended, the Americans With 
Disabilities Act of 1990, the Rehabilitation Act of 1973, as amended, the Em-

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ployee Retirement Income Security Act of 1974, as amended, the Age 
Discrimination in Employment Act of 1967, as amended, and the California Fair 
Employment and Housing Act.  Notwithstanding the generality of the foregoing, 
nothing contained herein shall release any of the Released Parties from their 
obligations under this Second Amendment and Release.

               b.   OFFICER'S WAIVER OF RIGHTS AFFORDED BY CALIFORNIA CIVIL 
CODE SECTION 1542.  Officer expressly waives all rights afforded by Section 
1542 of the Civil Code of the State of California ("Section 1542") with 
respect to the Released Parties.  Section 1542 states as follows:

         A GENERAL RELEASE DOES NOT EXTEND TO CLAIMS WHICH THE CREDITOR DOES
         NOT KNOW OR SUSPECT TO EXIST IN HIS FAVOR AT THE TIME OF EXECUTING THE
         RELEASE, WHICH IF KNOWN BY HIM MUST HAVE MATERIALLY AFFECTED HIS
         SETTLEMENT WITH THE DEBTOR.

Notwithstanding the provisions of Section 1542, and for the purpose of 
implementing a full and complete release, Officer understands and agrees that 
this Second Amendment and Release is intended to include all claims, if any, 
that Officer may have which he does not now know or suspect to exist in his 
favor against the Released Parties and this Second Amendment and Release 
extinguishes those claims.

          4.   REVIEW AND REVOCATION PERIOD.  Officer acknowledges that the 
Corporation has advised Officer that he may consult with an attorney of his 
choosing prior to signing this Second Amendment and Release and that Officer 
has twenty-one (21) days during which to consider the provisions of this 
Second Amendment and Release, although Officer may sign and return it sooner. 
 Officer further acknowledges that he has been advised by the Corporation 
that he has the right to revoke this Second Amendment and Release for a 
period of seven (7) days after signing it and that this Second Amendment and 
Release shall not become effective or enforceable until such seven (7)-day 
revocation period has expired. Officer acknowledges and agrees that if he 
wishes to revoke this Agreement, he must do so in writing, and that such 
revocation must be signed by Officer and received by the Corporation no later 
than 5:00 p.m. Pacific Standard Time on the seventh (7th) day after Officer 
has signed this Second Amendment and Release.  

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          5.   VOLUNTARY AGREEMENT.  Each Party to this Second Amendment and 
Release acknowledges and represents that he or it (a) has fully and carefully 
read this Second Amendment and Release prior to signing it,(b) has been, or 
has had the opportunity to be, advised by independent legal counsel of his or 
its own choice as to the legal effect and meaning of each of the terms and 
conditions of this Second Amendment and Release, and (c) is signing and 
entering into this Second Amendment and Release freely and voluntarily and 
without duress or undue pressure or influence of any kind or nature 
whatsoever and has not relied on any promises, representations or warranties 
regarding the subject matter hereof other than that which is set forth in 
this Second Amendment and Release.

          6.   BINDING EFFECT.  This Second Amendment and Release shall be 
binding upon the Parties and their respective heirs, administrators, 
representatives, executors, successors and assigns, and shall inure to the 
benefit of the Parties and their respective heirs, administrators, 
representatives, executors, successors and assigns.

          7.   GOVERNING LAW.  This Second Amendment and Release shall be 
construed and enforced pursuant to the laws of the State of California 
applicable to contracts made and entirely to be performed therein.

          8.   COUNTERPARTS.  This Second Amendment and Release may be 
executed in counterparts, each of which shall be an original and all of which 
together shall constitute one and the same agreement.

          9.   ENTIRE AGREEMENT; MODIFICATION.  This Second Amendment and
Release, together with the Employment Agreement, constitute the entire
understanding of the Parties and neither the Second Amendment and Release, nor
the Employment Agreement, may be modified except in a writing signed by the
Parties.  Other than as set forth herein, this Second Amendment and Release
supersedes all prior written and/or oral and all contemporaneous oral
agreements, understandings and negotiations regarding the subject matter hereof.

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          IN WITNESS WHEREOF, the Parties hereto have executed this Second 
Amendment and Release on the day and year first above written.

                                    CORPORATION:

                                    ALEXANDRIA REAL ESTATE EQUITIES, 
                                    INC., a Maryland corporation


                                    By:  /s/ Joel S. Marcus
                                       ---------------------------------------
                                        Joel S. Marcus
                                        Chief Executive Officer



                                    OFFICER:

                                     /s/ Jerry M. Sudarsky
                                    ---------------------------------------
                                    Jerry M. Sudarsky