EXHIBIT 5


                      OPINION AND CONSENT OF FISHER THURBER LLP








                                    April 16, 1998




Vyrex Corporation
2159 Avenida de la Playa
La Jolla, CA  92037

Dear Sirs:

     We refer to the Registration Statement on Form S-8 (the "Registration
Statement") to be filed with the Securities and Exchange Commission under the
Securities Act of 1933, as amended (the "Act"), on behalf of Vyrex Corporation,
a Nevada corporation (the "Company"), relating to 2,875,00 shares of the
Company's Common Stock, $.001 par value (the "Common Stock"), to be issued
pursuant to the Vyrex Corporation 1993 Stock Option Plan (the "Plan").

     As counsel to the Company, we have examined such corporate records, other
documents and such questions of law as we have deemed necessary or appropriate
for the purposes of this opinion and, upon the basis of such examinations,
advise you that in our opinion all necessary corporate proceedings by the
Company have been duly taken to authorize the issuance of the Common Stock
pursuant to the Plan and the shares of Common Stock being registered pursuant to
the Registration Statement, when issued and paid for in accordance with the
terms of the Plan, will be duly authorized, validly issued, fully paid and
non-assessable.

     We consent to the filing of this opinion as Exhibit 5 to the Registration
Statement.  This consent is not to be construed as an admission that we are a
person whose consent is required to be filed with the Registration Statement
under the provisions of the Act.

                              Very truly yours,

                                /s/ David A. Fisher

                              David A. Fisher

DAF:nxm