AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON MAY 19, 1998 REGISTRATION NO. 333- ___________ - ------------------------------------------------------------------------------ - ------------------------------------------------------------------------------ SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 ----------- FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 ----------- GENE LOGIC INC. (Exact name of Registrant as specified in its charter) ----------- Delaware 06-1411336 (State or other jurisdiction (I.R.S. Employer of incorporation or organization) Identification Number) 708 Quince Orchard Road Gaithersburg, Maryland 20878 (Address of principal executive offices) ----------- 1997 EQUITY INCENTIVE PLAN EMPLOYEE STOCK PURCHASE PLAN 1997 NON-EMPLOYEE DIRECTORS' STOCK OPTION PLAN (Full title of the plans) ----------- MICHAEL J. BRENNAN, M.D., PH.D. President and Chief Executive Officer GENE LOGIC INC. 708 Quince Orchard Road Gaithersburg, Maryland 20878 (301) 987-1700 (Name, address, including zip code, and telephone number, including area code, of agent for service) ----------- Copies to: Frederick T. Muto, Esq. L. Kay Chandler, Esq. COOLEY GODWARD LLP 4365 Executive Drive, Suite 1100 San Diego, CA 92121 (619) 550-6000 ----------- CALCULATION OF REGISTRATION FEE - ----------------------------------------------------------------------------------------------------- PROPOSED PROPOSED MAXIMUM MAXIMUM AMOUNT OF TITLE OF SECURITIES AMOUNT TO OFFERING PRICE AGGREGATE REGISTRATION TO BE REGISTERED BE REGISTERED PER SHARE (1) OFFERING PRICE (1) FEE - ----------------------------------------------------------------------------------------------------- Common Stock, $.01 par value 5,843,644 $0.15-8.50 $31,810,802 $9,384.19 - ----------------------------------------------------------------------------------------------------- (1) Estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rule 457. The price per share and aggregate offering price are based upon (a) the actual exercise price for shares subject to outstanding stock options previously granted under the Registrant's 1997 Equity Incentive Plan; and (b) the average of the high and low sales prices of Registrant's Common Stock on May 18, 1998, as reported on the Nasdaq National Market, for shares issuable under the Registrant's 1997 Equity Incentive Plan, Employee Stock Purchase Plan, and Non-Employee Directors' Stock Option Plan. The following chart shows the calculation of the registration fee: Number of Offering Price Aggregate Type of Shares Shares Per Share Offering Price -------------- --------- -------------- -------------- Common Stock issuable pursuant to outstanding 831,999 $0.15 $ 124,800 options under the 1997 Equity Incentive Plan Common Stock issuable pursuant to outstanding 94,500 $0.30 $ 28,350 options under the 1997 Equity Incentive Plan Common Stock issuable pursuant to outstanding 435,290 $1.00 $ 435,290 options under the 1997 Equity Incentive Plan Common Stock issuable pursuant to outstanding 765,633 $2.50 $1,914,083 options under the 1997 Equity Incentive Plan Common Stock issuable pursuant to outstanding 56,000 $3.50 $ 196,000 options under the 1997 Equity Incentive Plan Common Stock issuable pursuant to outstanding 73,000 $8.375 $ 611,375 options under the 1997 Equity Incentive Plan Common Stock issuable pursuant to outstanding 25,024 $7.9375 $ 198,628 options under the 1997 Equity Incentive Plan Common Stock issuable pursuant to outstanding 17,000 $8.0625 $ 137,063 options under the 1997 Equity Incentive Plan Common Stock issuable pursuant to outstanding 20,000 $8.50 $ 170,000 options under the 1997 Equity Incentive Plan Common Stock issuable pursuant to outstanding 28,500 $8.25 $ 235,125 options under the 1997 Equity Incentive Plan Common Stock issuable pursuant to outstanding 23,000 $8.438 $ 194,074 options under the 1997 Equity Incentive Plan Common Stock issuable pursuant to outstanding 1,000 $8.00 $ 8,000 options under the 1997 Equity Incentive Plan Common Stock issuable pursuant to outstanding 160,000 $7.875 $1,260,000 options under the 1997 Equity Incentive Plan Common Stock issuable pursuant to outstanding 3,000 $7.031 $ 21,093 options under the 1997 Equity Incentive Plan Common Stock issuable pursuant to outstanding 11,000 $8.313 $ 91,443 options under the 1997 Equity Incentive Plan Common Stock issuable pursuant to outstanding 11,000 $8.1250 $ 89,375 options under the 1997 Equity Incentive Plan Common Stock issuable pursuant to the 1997 2,912,698 $7.9375 $23,119,540 Equity Incentive Plan Common Stock issuable pursuant to the Employee 250,000 $7.9375 $1,984,375 Stock Purchase Plan Common Stock issuable under the 1997 Non-Employee 125,000 $7.9375 $ 992,188 Directors' Stock Option Plan PART II INFORMATION REQUIRED IN THE REGISTRATION STATEMENT ITEM 3. INCORPORATION OF DOCUMENTS BY REFERENCE. The prospectus contained in the Form S-1 Registration Statement (No. 333-37317) filed by Gene Logic Inc. (the "Registrant") with the Securities and Exchange Commission (the "Commission") on October 7, 1997, as amended through the date hereof (the "Form S-1"), is hereby incorporated by reference into this Registration Statement. Registrant also incorporates by reference its Annual Report on Form 10-K for the year ended December 31, 1997, filed on March 31, 1998 and its Quarterly Report on Form 10-Q for the quarter ended March 31, 1998, filed on May 14, 1998 pursuant to Sections 13 or 15(d) of the Securities Exchange Act of 1934, as amended (the "Exchange Act"). A description of the Registrant's Common Stock which is contained in the Form S-1, including any amendment or reports filed for the purpose of updating such description, is hereby incorporated by reference into this Registration Statement. All documents filed by the Registrant with the Commission pursuant to Sections 13(a), 13(c), 14 or 15(d) of the Exchange Act after the date of this Registration Statement and prior to the filing of a post-effective amendment which indicates that all securities offered have been sold or which deregisters all securities then remaining unsold shall be deemed to be incorporated by reference into this Registration Statement and to be a part hereof from the date of filing of such documents. Any statement contained in a document incorporated by reference herein shall be deemed to be modified or superseded for purposes of this Registration Statement to the extent that a statement contained herein or in any other subsequently filed document which also is or is deemed to be incorporated by reference herein modifies or supersedes such statement. Any statement so modified or superseded shall not be deemed, except as so modified or superseded, to constitute a part of this Registration Statement. ITEM 4. DESCRIPTION OF SECURITIES. Not applicable. ITEM 5. INTERESTS OF NAMED EXPERTS AND COUNSEL. The validity of the shares of Common Stock offered hereby will be passed upon for the Company by Cooley Godward LLP, San Diego, California. ITEM 6. INDEMNIFICATION OF DIRECTORS AND OFFICERS. Under Section 145 of the Delaware General Corporation Law, the Registrant has broad powers to indemnify its Directors and officers against liabilities they may incur in such capacities, including liabilities under the Securities Act. The Registrant's Restated Certificate of Incorporation and Amended and Restated By-laws include provisions to (i) eliminate the personal liability of its Directors for monetary damages resulting from breaches of their fiduciary duty to the extent permitted by Section 102(b)(7) of the General Corporation Law of Delaware (the "Delaware Law") and (ii) require the Registrant to indemnify its Directors and officers to the fullest extent permitted by Section 145 of the Delaware Law, including circumstances in which indemnification is otherwise discretionary. Pursuant to Section 145 of the Delaware Law, a corporation generally has the power to indemnify its present and former directors, officers, employees and agents against expenses incurred by them in connection with any suit to which they are or are threatened to be made a party by reason of their serving in such positions so long as they acted in good faith and in a manner they reasonably believed to be in or not opposed to, the best interests 1 of the corporation and with respect to any criminal action, they had no reasonable cause to believe their conduct was unlawful. The Registrant believes that these provisions are necessary to attract and retain qualified persons as Directors and officers. These provisions do not eliminate the Directors' duty of care, and, in appropriate circumstances, equitable remedies such as injunctive or other forms of non-monetary relief will remain available under Delaware Law. In addition, each Director will continue to be subject to liability for breach of the Director's duty of loyalty to the Registrant, for acts or omissions not in good faith or involving intentional misconduct, for knowing violations of law, for acts or omissions that the Director believes to be contrary to the best interests of the Registrant or its stockholders, for any transaction from which the Director derived an improper personal benefit, for acts or omissions involving a reckless disregard for the Director's duty to the Registrant or its stockholders when the Director was aware or should have been aware of a risk of serious injury to the Registrant or its stockholders, for acts or omissions that constitute an unexcused pattern of inattention that amounts to an abdication of the Director's duty to the Registrant or its stockholders, for improper transactions between the Director and the Registrant and for improper distributions to stockholders and loans to Directors and officers. The provision also does not affect a Director's responsibilities under any other law, such as the federal securities law or state or federal environmental laws. The Registrant has entered into indemnity agreements with each of its Directors and executive officers that require the Registrant to indemnify such persons against expenses, judgments, fines, settlements and other amounts incurred (including expenses of a derivative action) in connection with any proceeding, whether actual or threatened, to which any such person may be made a party by reason of the fact that such person is or was Director or an executive officer of the Registrant or any of its affiliated enterprises, provided that such person acted in good faith and in a manner such person reasonably believed to be in or not opposed to the best interests of the Registrant and, with respect to any criminal proceeding, had no reasonable cause to believe his conduct was unlawful. The indemnification agreements also set forth certain procedures that will apply in the event of a claim for indemnification thereunder. At present, there is no pending litigation or proceeding involving a Director, officer or key employee of the Registrant as to which indemnification is being sought nor is the Registrant aware of any threatened litigation that may result in claims for indemnification by any officer or Director. The Registrant has an insurance policy covering the officers and Directors of the Registrant with respect to certain liabilities, including liabilities arising under the Securities Act or otherwise. ITEM 7. EXEMPTION FROM REGISTRATION CLAIMED. Not applicable. ITEM 8. EXHIBITS. EXHIBIT NO. DESCRIPTION 4.1 Amended and Restated Certificate of Incorporation. (1) 4.2 By-laws, as amended and restated. (1) 4.3 Specimen Stock Certificate. (1) 5.1 Opinion of Cooley Godward LLP. 23.1 Consent of Arthur Andersen LLP, Independent Auditors. 23.2 Consent of Cooley Godward LLP. Reference is made to Exhibit 5.1. 2 EXHIBIT NO. DESCRIPTION 24.1 Power of Attorney. Reference is made to page 5. 99.1 Registrant's 1997 Equity Incentive Plan (the "1997 Plan"). (1) 99.2 Form of Stock Option Agreement under the 1997 Plan. (1) 99.3 Form of Stock Option Grant Notice under the 1997 Plan. (1) 99.4 Registrant's Employee Stock Purchase Plan and related offering document. (1) 99.5 Registrant's 1997 Non-Employee Directors' Stock Option Plan. (1) 99.6 Form of Nonstatutory Stock Option under Registrant's 1997 Non-Employee Directors' Stock Option Plan. (1) - --------------- (1) Filed as an exhibit to Registration Statement on Form S-1 (No. 333-37317) originally filed on October 7, 1997, as amended through the date hereof, and incorporated herein by reference. ITEM 9. UNDERTAKINGS. 1. The undersigned Registrant hereby undertakes: (a) To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement: (i) To include any prospectus required by Section 10(a)(3) of the Securities Act; (ii) To reflect in the prospectus any facts or events arising after the effective date of the Registration Statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the Registration Statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in the form of prospectus filed with the Commission pursuant to Rule 424(b) if, in the aggregate, the changes in volume and price represent no more than a 20% change in the maximum aggregate offering price set forth in the "Calculation of Registration Fee" table in the effective Registration Statement; (iii) To include any material information with respect to the plan of distribution not previously disclosed in the Registration Statement or any material change to such information in the Registration Statement; PROVIDED, HOWEVER, that paragraphs (1)(a)(i) and (1)(a)(ii) above do not apply if the information required to be included in a post-effective amendment by those paragraphs is contained in periodic reports filed with or furnished to the Commission by the Registrant pursuant to Section 13 or Section 15(d) of the Securities Exchange Act of 1934 that are incorporated by reference in this Registration Statement; (b) That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial BONA FIDE offering thereof. (c) To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering. 3 2. The undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the Registrant's annual report pursuant to Section 13(a) or Section 15(d) of the Exchange Act of 1934 (and, where applicable, each filing of an employee benefit plan's annual report pursuant to Section 15(d) of the Exchange Act of 1934) that is incorporated by reference in the Registration Statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial BONA FIDE offering thereof. 3. Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the Registrant pursuant to the foregoing provisions, or otherwise, the Registrant has been advised that in the opinion of the Securities and Exchange Commission such indemnification is against public policy as expressed in the Act, and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against public policy as expressed in the Act and will be governed by the final adjudication of such issue. 4 SIGNATURES Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Gaithersburg, State of Maryland, on May 19, 1998. GENE LOGIC INC. By: /s/Michael J. Brennan ------------------------------- Michael J. Brennan, M.D., Ph.D. President and Chief Executive Officer POWER OF ATTORNEY KNOW ALL PERSONS BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints Michael J. Brennan, M.D., Ph.D., and Mark D. Gessler, and each or any one of them, his true and lawful attorney-in-fact and agent, with full power of substitution and resubstitution, for him and in his name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective amendments, exhibits thereto and other documents in connection with) to this Registration Statement, and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorney-in-fact and agent full power and authority to do and perform each and every act and thing requisite and necessary to be done in connection therewith, as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorney-in-fact and agent, or his substitutes or substitute, may lawfully do or cause to be done by virtue hereof. Pursuant to the requirements of the Securities Act, this Registration Statement has been signed by the following persons in the capacities and on the dates indicated. SIGNATURE TITLE DATE /s/ Michael J. Brennan President, Chief Executive Officer and May 19, 1998 - -------------------------------- Director (PRINCIPAL EXECUTIVE OFFICER) Michael J. Brennan, M.D., Ph.D. /s/ Mark D. Gessler Senior Vice President, Corporate Development May 19, 1998 - -------------------------------- and Chief Financial Officer (PRINCIPAL Mark D. Gessler FINANCIAL AND ACCOUNTING OFFICER) /s/ Alan G. Walton Chairman of the Board of Directors May 19, 1998 - -------------------------------- Alan G. Walton, Ph.D., D.Sc. /s/ Jules Blake Director May 19, 1998 - -------------------------------- Jules Blake, Ph.D. /s/ Charles L. Dimmler III Director May 19, 1998 - -------------------------------- Charles L. Dimmler III /s/ G. Anthony Gorry Director May 19, 1998 - -------------------------------- G. Anthony Gorry, Ph.D. /s/ Jeffrey D. Sollender Director May 19, 1998 - -------------------------------- Jeffrey D. Sollender 5 EXHIBIT INDEX EXHIBIT NO. DESCRIPTION 4.1 Amended and Restated Certificate of Incorporation. (1) 4.2 By-laws, as amended and restated. (1) 4.3 Specimen Stock Certificate. (1) 5.1 Opinion of Cooley Godward LLP. 23.1 Consent of Arthur Andersen LLP, Independent Auditors. 23.2 Consent of Cooley Godward LLP. Reference is made to Exhibit 5.1. 24.1 Power of Attorney. Reference is made to page 5. 99.1 Registrant's 1997 Equity Incentive Plan (the "1997 Plan"). (1) 99.2 Form of Stock Option Agreement under the 1997 Plan. (1) 99.3 Form of Stock Option Grant Notice under the 1997 Plan. (1) 99.4 Registrant's Employee Stock Purchase Plan and related offering document. (1) 99.5 Registrant's 1997 Non-Employee Directors' Stock Option Plan. (1) 99.6 Form of Nonstatutory Stock Option under Registrant's 1997 Non-Employee Directors' Stock Option Plan. (1) - ----------------- (1) Filed as an exhibit to Registration Statement on Form S-1 (No. 333-37317) originally filed on October 7, 1997, as amended through the date hereof, and incorporated herein by reference.