EXHIBIT 10.5
                              SEVERANCE AGREEMENT

              THIS AGREEMENT, dated January 1, 1999, (the "Effective Date") 
is made by and between Alexandria Real Estate Equities, Inc., a Maryland 
corporation (the "Company"), and Lynn A. Shapiro ("Executive").

              WHEREAS, the Company considers it essential to the best 
interests of its stockholders to foster the continued employment of key 
management personnel; and
              
              WHEREAS, the Board of Directors has determined that appropriate 
steps should be taken to reinforce and encourage the continued attention and 
dedication of members of the Company's management, including Executive, who 
shall serve as General Counsel and Assistant Secretary of the Company.

              NOW, THEREFORE, the Company and Executive hereby agree as 
follows:

       1.     TERM OF AGREEMENT.

              The term of this Agreement shall commence on the Effective Date 
and shall continue in effect through the first anniversary of the Effective 
Date (the "Term"); PROVIDED, HOWEVER, that on each anniversary of the 
Effective Date during the Term, the Term shall automatically be extended for 
one additional year unless, not later than 90 days prior to any such 
anniversary, the Company or Executive shall have given written notice not to 
extend the Term.

       2.     COMPENSATION OTHER THAN SEVERANCE PAYMENTS.

              If Executive's employment shall be terminated for any reason 
during the Term, the Company shall pay Executive's full salary to Executive 
accrued through the date of Executive's termination of employment (the "Date 
of Termination") at the rate in effect immediately prior to the Date of 
Termination.



       3.     SEVERANCE PAYMENTS.

              If  Executive's employment is terminated by the Company other 
than for Cause (as defined below), then the Company shall pay Executive a 
severance payment equal to nine (9) months ("Severance Period") of 
Executive's annualized base salary ("Severance Payments"), in addition to any 
payments to which Executive is entitled under Section 2 hereof. Such 
Severance Payments shall be payable in substantially equal semimonthly 
installments during the Severance Period in accordance with the standard 
policies of the Company in existence from time-to-time; provided, that if 
such termination is within six months following a Change in Control (as 
defined below), the Company shall pay Executive such Severance Payment in a 
lump sum within sixty (60) days following a Change in Control.  In addition, 
if  Executive's employment is terminated by the Company other than for Cause 
within six months following a Change in Control, the vesting of any options 
held by Executive to purchase shares of stock of the Company shall 
immediately accelerate upon such termination following a Change in Control.

              Executive shall not be entitled to receive a Severance Payment 
hereunder if she voluntarily terminates her employment or is terminated by 
reason of death or disability or for Cause. 

              3.1    CAUSE.  For purposes of this Agreement, "Cause" shall mean
the following:

              (i)    Executive's Material breach, repudiation or failure to
                     comply with or perform any of the terms of this Agreement,
                     any of Executive's duties, or any of the Company's policies
                     or procedures (including without limitation any such
                     policies or procedures relating to conflicts of interests
                     or standards of business conduct) or deliberate
                     interference with the compliance by any other employee of
                     the Company with any of the foregoing;

              (ii)   the conviction of Executive for, or pleading by Executive
                     of no contest (or similar plea) to, fraud, embezzlement,
                     misappropriation of assets, malicious mischief, or any
                     felony, other than a crime for which vicarious liability is
                     imposed upon Executive solely by reason of Executive's
                     position with the Company and not by reason of Executive's
                     conduct; or


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              (iii)  any other act, omission, event or condition constituting
                     cause for the discharge of any employee under applicable
                     law.

              Before terminating the Agreement for Cause, the Company first 
shall have given Executive written notice specifying the nature of the 
breach, repudiation or failure to comply and thirty (30) days thereafter in 
which to cure such breach, repudiation or failure to comply, and Executive 
shall have failed to cure.  For purposes of this Section 3, "Material" shall 
mean a breach, repudiation or failure that the Board determines has resulted 
or could result in material injury to the Company.

              3.2    CHANGE IN CONTROL  for purposes of this agreement, a 
"Change in Control" shall be deemed to have occurred if:

                     (i)  Any Person, as such term is used in section 3(a)(9) 
of the Securities Exchange Act of 1934, as amended from time-to-time (the 
"Exchange Act"), as modified and used in sections 13(d) and 14(d) thereof, 
(other than (A) the Company or any of its subsidiaries, (B) a trustee or 
other fiduciary holding securities under an employee benefit plan of the 
Company or any of its affiliates, (C) an underwriter temporarily holding 
securities pursuant to an offering of such securities, (D) a corporation 
owned, directly or indirectly, by the stockholders of the Company in 
substantially the same proportions as their ownership of stock of the 
Company, or (E) a person or group as used in Rule 13d-1(b) under the Exchange 
Act) is or becomes the Beneficial Owner, as such term is defined in Rule 
13d-3 under the Exchange Act, directly or indirectly, of securities of the 
Company (not including in the securities beneficially owned by such Person 
any securities acquired directly from the Company or its affiliates other 
than in connection with the acquisition by the Company or its affiliates of a 
business) representing twenty-five percent (25%) or more of the combined 
voting power of the Company's then outstanding securities; or  

                     (ii)  The following individuals cease for any reason to 
constitute a majority of the number of directors then serving:  individuals 
who, on the date hereof, constitute the Board and any new director (other 
than a director whose initial assumption of office is in connection with an 
actual or threatened election contest, including but not limited to a consent 
solicitation, relating to the election of directors of the Company) whose 
appointment or election by the Board or nomination for election by the 
Company's stockholders was approved or recommended 

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by a vote of at least two-thirds (2/3) of the directors then still in office 
who either were directors on the date hereof or whose appointment, election 
or nomination for election was previously so approved or recommended; or 

                     (iii)  There is consummated a merger or consolidation of 
the Company with any other corporation, other than (A) a merger or 
consolidation which would result in the voting securities of the Company 
outstanding immediately prior to such merger or consolidation continuing to 
represent (either by remaining outstanding or by being converted into voting 
securities of the surviving entity or any parent thereof), in combination 
with the ownership of any trustee or other fiduciary holding securities under 
an employee benefit plan of the Company or any subsidiary of the Company, at 
least seventy-five percent (75%) of the combined voting power of the 
securities of the Company or such surviving entity or any parent thereof 
outstanding immediately after such merger or consolidation, or (B) a merger 
or consolidation effected to implement a recapitalization of the Company (or 
similar transaction) in which no Person is or becomes the Beneficial Owner, 
directly or indirectly, of securities of the Company (not including in the 
securities beneficially owned by such Person any securities acquired directly 
from the Company or its affiliates other than in connection with the 
acquisition by the Company or its affiliates of a business) representing 
twenty-five percent (25%) or more of the combined voting power of the 
Company's then outstanding securities; or 

                     (iv)  The stockholders of the Company approve a plan of 
complete liquidation or dissolution of the Company or there is consummated an 
agreement for the sale or disposition by the Company of all or substantially 
all of the Company's assets, other than a sale or disposition by the Company 
of all or substantially all of the Company's assets to an entity, at least 
seventy-five (75%) of the combined voting power of the voting securities of 
which are owned by stockholders of the Company in substantially the same 
proportions as their ownership of the Company immediately prior to such sale.

       4.     OFFSET.  

              Although Executive shall not be required to mitigate damages 
under this Agreement by seeking other comparable employment or otherwise, the 
amount of any payment or benefit provided for in this Agreement shall be 
reduced by any compensation earned by or provided to Executive as the result 
of employment by an employer other than the Company prior to the expiration 
of the Term.

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       5.     NONCOMPETITION.

              During the Term, including the period, if any, with respect to 
which Executive shall be entitled to Severance Payments, Executive shall not 
engage in any activity that is or may be competitive with the business of the 
Company, directly or indirectly, whether or not for compensation, including, 
but not limited to, providing services similar to those provided by the 
Company; offering or soliciting or accepting an offer, to provide such 
services or taking any action to form, or become employed by, a firm or 
business to provide such services.

       6.     MISCELLANEOUS.

              6.1.   CONFIDENTIALITY.  Without limiting the scope of the 
Agreement Regarding Proprietary Information between the Parties, dated as of 
May 13, 1998 (the "Proprietary Information Agreement"), Executive agrees that 
all confidential and proprietary information relating to the business of the 
Company shall be kept and treated as confidential both during and after the 
Term of this Agreement, except as may be permitted in writing by the Board or 
as such information is within the public domain or comes within the public 
domain without any breach of this Agreement.

              6.2.   WAIVER.  The waiver of the breach of any provision of 
this Agreement shall not operate or be construed as a waiver of any 
subsequent breach of the same or other provision hereof.

              6.3.   ENTIRE AGREEMENT; MODIFICATIONS.  Except as otherwise 
provided herein, this Agreement (together with the Proprietary Information 
Agreement and any other agreements and plans referred to herein) represents 
the entire understanding between Executive and the Company with respect to 
the subject matter hereof, and this Agreement supersedes any and all prior 
understandings, agreements, plans and negotiations, whether written or oral, 
with respect to the subject matter hereof, including without limitation any 
understandings, agreements or obligations respecting any past or future 
compensation, bonuses, reimbursements or other payments to Executive from the 
Company.  All modifications to this Agreement must be in writing and signed 
by the party against whom enforcement of such modification is sought.

              6.4.   NOTICES.  All notices and other communications under 
this Agreement shall be in writing and shall be given by facsimile or 
first-class mail, 

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certified or registered with return receipt requested, and shall be deemed to 
have been duly given three (3) days after mailing or twenty-four (24) hours 
after transmission of a facsimile to the respective persons named below:

              If to The Company:   Alexandria Real Estate Equities, Inc.
                                   135 North Los Robles Avenue, Suite 250
                                   Pasadena, CA  91101
                                   Phone:        (626) 578-0777
                                   Facsimile:    (626) 578-0770
                                   Attn:   Joel S. Marcus, CEO

              If to Executive:     Lynn A. Shapiro
                                   22 Bermuda Court
                                   Manhattan Beach, CA 90266
                                   Phone: (310) 546-7920
                                   

              6.5.   HEADINGS.  The Paragraph headings herein are intended 
for reference only and shall not determine the construction or interpretation 
of this Agreement.

              6.6.   GOVERNING LAW.   This Agreement shall be governed by and 
construed in accordance with the laws of the State of California without 
regard to its principles of conflicts of laws.

              6.7.   ARBITRATION.  Any dispute arising out of or relating to 
this Agreement that cannot be settled by good faith negotiation between the 
Parties shall be submitted to ENDISPUTE for final and binding arbitration 
pursuant to ENDISPUTE's Arbitration Rules incorporated herein by reference, 
which arbitration shall take place in Los Angeles, California and shall be 
the exclusive remedy of the Parties hereto.  The resulting arbitration shall 
be deemed a final order of a court having jurisdiction over the subject 
matter, shall not be appealable, and shall be enforceable in any court of 
competent jurisdiction.  Submission to arbitration shall not preclude the 
right of any party hereto involved in a dispute regarding this Agreement 
(each a "Disputing Party" and collectively, the "Disputing Parties") to 
institute proceedings at law or in equity for injunctive or other relief 
pending the arbitration of a matter subject to arbitration pursuant to this 
Agreement.  Any documentation and information submitted by any party in the 

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arbitration proceeding shall be kept strictly confidential by the Parties and 
the arbitrator.

              In addition to any other relief or award granted by the 
arbitrator to either Disputing Party, the arbitrator shall determine the 
extent to which each Disputing Party has prevailed as to the material issues 
raised in the arbitration, and, based upon such determination, shall 
apportion to each Disputing Party its ratable share of (i) the Disputing 
Parties' reasonable attorneys' fees and other costs reasonably incurred in 
the arbitration, (ii) the expense of the arbitrator, and (iii) all other 
expenses of the arbitration. The arbitrator shall make such determination and 
apportionment whether or not the dispute proceeds to a final award. 

              6.8.   SEVERABILITY.  Should a court or other body of competent 
jurisdiction determine that any provision of this Agreement is excessive in 
scope or otherwise invalid or unenforceable, such provision shall be adjusted 
rather than voided, if possible, and all other provisions of this Agreement 
shall be deemed valid and enforceable to the extent possible.

              6.9.   COUNTERPARTS.  This Agreement may be executed in one or 
more counterparts, all of which taken together shall constitute one and the 
same Agreement.


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              IN WITNESS WHEREOF, the Parties hereto have executed this 
Agreement.

                                       The Company:

                                       ALEXANDRIA REAL ESTATE 
                                       EQUITIES, INC.
                                       a Maryland corporation


                                       By: /s/ JOEL S. MARCUS
                                          -------------------------------------
                                           Joel S. Marcus
                                           Chief Executive Officer

                                       Date:  May [   ], 1998


                                       EXECUTIVE:

                                       /s/ LYNN ANNE SHAPIRO
                                       -------------------------------------
                                       Lynn A. Shapiro 


                                       Date:  January 1, 1999




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