AMENDED AND RESTATED

                          CERTIFICATE OF DETERMINATION OF

                               PREFERENCES AND RIGHTS

                                         OF

                        SERIES A CONVERTIBLE PREFERRED STOCK

                                         OF

                                ISONICS CORPORATION

                                   *   *   *   *

     The undersigned, James E. Alexander and Brantley J. Halstead, certify that:

1.   They are the duly acting President and Secretary, respectively, of
ISONICS CORPORATION, a corporation organized and existing under the
Corporations Code of the State of California (the "Corporation").

2.   That, pursuant to authority conferred upon the Board of Directors by the
Articles of Incorporation of the Corporation, and pursuant to the provisions
of Section 401 of Title 1 of the Corporations Code of the State of
California, said Board of Directors, pursuant to an action by unanimous
consent dated July 26, 1999, adopted a resolution mending and restating the
rights, preferences, privileges and restrictions of, and the number of shares
comprising, the Corporation's Series A Convertible Preferred Stock, which
resolution is as follows:

          RESOLVED, that a series of Preferred Stock in Isonics Corporation, a
     California corporation (the "Corporation"), having the rights, preferences,
     privileges and restrictions, and the number of shares constituting such
     series and the designation of such series, set forth below be, and it
     hereby is, authorized by the Board of Directors of the Corporation pursuant
     to authority given by the Corporation's Articles of Incorporation.



          1.   NUMBER AND DESIGNATION.  This series shall consist of 1,850,000
     shares of Preferred Stock of the Corporation and shall be designated the
     Series A Convertible Preferred Stock ("Series A Stock").  The number of
     authorized shares of Series A Stock may be reduced to the extent any shares
     are not issued and outstanding by further resolution duly adopted by the
     Board of Directors of the Corporation and by filing amendments to the
     Certificate of Determination pursuant to the provisions of the Corporations
     Code of the State of California stating that such reduction has been so
     authorized, but the number of authorized shares of this Series shall not be
     increased except pursuant to majority vote of the Series A Holders.  None
     of the shares of Series A Stock has been issued.

          2.   DIVIDENDS.  When and as any dividend or distribution is declared
     or paid by the Corporation on Common Stock, whether payable in cash,
     property, securities or rights to acquire securities, the Series A Holders
     will be entitled to participate with the holders of Common Stock in such
     dividend or distribution as set forth in this Section 2.  At the time such
     dividend or distribution is payable to the holders of Common Stock, the
     Corporation will pay to each Series A Holder such holder's share of such
     dividend or distribution equal to the amount of the dividend or
     distribution per share of Common Stock payable at such time multiplied by
     the number of shares of Common Stock then obtainable upon conversion of
     such holder's Series A Stock.

     3.   VOTING RIGHTS.

               A.   The Series A Holders shall be entitled to notice of any
     shareholders' meeting and to vote as a single class with the Common Stock
     upon any matter submitted for approval by the holders of Common Stock on
     the following basis: the Series A Holders shall have that number of votes
     equal to the number of shares of Common Stock into which such Series A
     Stock is then convertible.

               B.   In addition to any other rights provided by law, so long as
     any Series A Stock is outstanding, the Corporation, without first obtaining
     the affirmative vote or written consent of the holders of not less than a
     majority of such outstanding shares of Series A Stock, will not:

               (i)   amend or repeal any provision of, or add any provision to,
          the Corporation's Articles of Incorporation or By-Laws if such action
          would alter adversely the liquidation preferences of, or the rights or
          restrictions provided for the benefit of, any Series A Stock;

               (ii)  authorize or issue shares of any class or series of stock
          not expressly authorized herein having any preference or priority as
          to



          dividends, voting or liquidation or other rights superior to any
          such preference or priority of the Series A Stock, or authorize or
          issue shares of stock of any class or any bonds, debentures, notes or
          other obligations convertible into or exchangeable for, or having
          option rights to purchase, any shares of stock of the Corporation
          having any preference or priority as to dividends, voting or
          liquidation or other rights superior to any such preference or
          priority of the Series A Stock;

               (iii) reclassify any class or series of stock junior to the
          Series A Stock into stock senior to the Series A Stock with respect to
          any preference or priority;

               (iv)  issue any class(es) or series of equity security(ies)
          which (a) is (are) convertible directly or indirectly into Common
          Stock at a rate related to the market price of the Common Stock or
          other such variable basis (other than normal anti-dilution provisions)
          or (b), in any transaction or series of transactions over a 12 month
          period, constitute(s) 15% or more of the outstanding Common Stock of
          the Corporation, assuming conversion or exercise in full of any
          Convertible Securities included in such securities;

               (v)   elect to windup, dissolve or liquidate the Corporation or
          revoke any such election; or

               (vi)  sell or otherwise dispose of (including without limitation
          through lease, mortgage, licensing, joint venture, exchange, transfer
          or similar arrangements) all or a significant portion of the Silicon
          Isotope Business.


     4.   PREFERENCE UPON LIQUIDATION.

               A.    Upon any liquidation, dissolution or winding up of the
     Corporation, each Series A Holder will be entitled to be paid, before any
     distribution or payment is made upon any Junior Securities of the
     Corporation, an amount in cash equal to the aggregate Liquidation Value (as
     defined in Section 7C below) of all shares of Series A Stock held by such
     holder, plus accrued dividends, if any; thereafter, each Series A Holder
     will participate in any distribution or payment on a pro rata basis with
     all Junior Securities as if the Series A Stock had been converted into
     Common Stock.

               B.    The reorganization, consolidation or the merger of the
     Corporation into or with any other corporation(s) or other entity(ies)



     ("Reorganization"), the sale, lease, licensing, exchange or other transfer
     by the Corporation of all or any significant part of its assets or the
     commencement by the Corporation of a voluntary case under the United States
     bankruptcy laws or any applicable bankruptcy, insolvency or similar law of
     any other country, or consent to the entry of an order for relief in an
     involuntary case under any such law or to the appointment of a receiver,
     liquidator, assignee, custodian, trustee, sequestrator (or other similar
     official) of the Corporation or of any substantial part of its property, or
     the making of an assignment for the benefit of its creditors, or an
     admission in writing of its inability to pay its debts generally as they
     become due, will be deemed to be a liquidation, dissolution or winding up
     of the Corporation within the meaning of this Section 4; PROVIDED THAT,
     with the consent of the Series A Holders acting by a majority vote (the
     "Reorganization Consent"), a Reorganization of the Corporation shall not be
     deemed to be a liquidation, dissolution or winding up of the Corporation
     within the meaning of this Section 4 if (i) the principal agreement for
     such Reorganization shall expressly provide that the Series A Stock shall
     become preferred stock of such surviving entity with the equivalent rights
     to the rights set forth herein ("Surviving Entity Preferred Stock"), (ii)
     the holders of Junior Securities receive, in exchange for such Junior
     Securities, common stock or preferred stock in the surviving entity
     (whether or not the surviving entity is the Corporation) of such
     Reorganization, or common stock or preferred stock of another entity, which
     is junior as to dividends and upon liquidation, dissolution or winding up
     to the Series A Stock or Surviving Entity Preferred Stock, as applicable,
     and (iii) the Series A Holders shall be entitled to receive at the option
     of each Series A Holder (A) either the Surviving Entity Preferred Stock or
     (B) the kind and amount of shares or other securities or property which
     they would have been entitled to receive had they converted their shares of
     Series A Stock into shares of Common Stock of the Corporation as of the
     record date for the determination of holders of Common Stock entitled to
     cast their votes for or against or to express any dissent to such
     Reorganization.  After any such Reorganization and Reorganization Consent,
     the rights of such holders of Surviving Entity Preferred Stock with respect
     to the adjustment of the Conversion Price shall be appropriately continued
     and preserved in order to afford, as nearly as possible, protection against
     dilution of the conversion rights and privileges comparable to those
     conferred herein.



     5.   CONVERSION INTO CONVERSION STOCK; SILICON ISOTOPE TRANSACTION.

          A.   CONVERSION.

                     (i) At any time prior to the Redemption Date (as
          defined in Section 6 B below), any Series A Holder may convert all or
          any portion of such holder's shares of Series A Stock into a number of
          shares of the Conversion Stock computed by multiplying the number of
          shares to be converted by $1.50 and dividing the result by the
          Conversion Price then in effect.  For purposes of this Section,
          "Conversion Stock" means the Common Stock.

                     (ii)     Each conversion of Series A Stock will be deemed
          to have been effected as of the close of business on the date on which
          the certificate or certificates representing the Series A Stock to be
          converted have been surrendered at the principal office of the
          Corporation.  At such time as such conversion has been effected, the
          rights of the holder of such Series A Stock as such holder will cease
          and the person or persons in whose name or names any certificate or
          certificates for shares of Conversion Stock are to be issued upon such
          conversion will be deemed to have become the holder or holders of
          record of the shares of Conversion Stock represented thereby.

                     (iii)    As soon as possible after a conversion has been
          effected, the Corporation will deliver to the converting holder:

                     (a) a certificate or certificates representing the
               number of shares of Conversion Stock issuable by reason of such
               conversion in such name or names and such denomination or
               denominations as the converting holder has specified; and

                     (b) a certificate representing any shares of Series A
               Stock which were represented by the certificate or certificates
               delivered to the Corporation in connection with such conversion
               but which were not converted.

                     (iv)     If any fractional share of Conversion Stock would
          be issuable upon any conversion, the Corporation will pay the holder
          of the Conversion Stock the fair market value of such fractional
          share.

                     (v)      The issuance of certificates for shares of
          Conversion Stock upon conversion of Series A Stock will be made
          without charge.



                     (vi)     The Corporation will not close its books against
          the transfer of Series A Stock or of Conversion Stock issued or
          issuable upon conversion of Series A Stock in any manner which
          interferes with the conversion of Series A Stock.

               B.    CONVERSION PRICE.  The initial Conversion Price for the
     Series A Stock will be $1.50.  In order to prevent dilution of the
     conversion rights granted under this Section, the Conversion Price will be
     subject to adjustment from time to time pursuant to this Section 5.



               C.    SUBDIVISION OR COMBINATION OF COMMON STOCK; DISSOLUTION.

               (i)   If the Corporation at any time subdivides (by any stock
     split, stock dividend or otherwise) its outstanding shares of Common Stock
     into a greater number of shares, the Conversion Price in effect immediately
     prior to such subdivision will be proportionately reduced, and if the
     Corporation at any time combines (by reverse stock split or otherwise) its
     outstanding shares of Common Stock into a smaller number of shares, the
     Conversion Price in effect immediately prior to such combination will be
     proportionately increased.

               (ii)  In the event of a judicial or non-judicial dissolution of
     the Corporation, the conversion rights and privileges of the Series A
     Holders shall terminate on a date, as fixed by the Board of Directors of
     the Corporation, not more than 45 days and not less than 30 days before the
     date of such dissolution. The reference to shares of Common Stock herein
     shall be deemed to include shares of any class into which said shares of
     Common Stock may be changed.

               D.    OTHER ADJUSTMENTS.

               (i)   GENERAL.  In any case to which Section 5C hereof is not
          applicable, where the Corporation shall issue or sell shares of its
          Common Stock after the Original Issue Date for a consideration per
          share less than the Conversion Price in effect pursuant to the terms
          of the Series A Stock at the time of issuance or sale of such
          additional shares (the "Lower Exercise Price"), then the Conversion
          Price in effect hereunder shall simultaneously with such issuance or
          sale be reduced to the Lower Exercise Price.

               (ii)  CONVERTIBLE SECURITIES.



                         (a)  In case the Corporation shall issue or sell any
          securities convertible into Common Stock of the Corporation
          ("Convertible Securities") after the Original Issue Date, there shall
          be determined the price per share for which Common Stock is issuable
          upon the conversion or exchange thereof, such determination to be made
          by dividing (1) the total amount received or receivable by the
          Corporation as consideration for the issue or sale of such Convertible
          Securities, plus the minimum aggregate amount of additional
          consideration, if any, payable to the Corporation upon the conversion
          or exchange thereof, by (2) the maximum number of shares of Common
          Stock of the Corporation issuable upon the conversion or exchange of
          all of such Convertible Securities.

                         (b)  If the price per share so determined shall be less
          than the applicable Conversion Price, then such issue or sale shall be
          deemed to be an issue or sale for cash (as of the date of issue or
          sale of such Convertible Securities) of such maximum number of shares
          of Common Stock at the price per share so determined, provided that,
          if such Convertible Securities shall by their terms provide for an
          increase or increases or decrease or decreases with the passage of
          time, in the amount of additional consideration, if any, to the
          Corporation, or in the rate of exchange, upon the conversion or
          exchange thereof, the adjusted Conversion  Price shall, forthwith upon
          any such increase or decrease becoming effective, be readjusted to
          reflect the same, and provided further, that upon the expiration of
          such rights of conversion or exchange of such Convertible Securities,
          if any thereof shall not have been exercised, the adjusted Conversion
          Price shall forthwith be readjusted and thereafter be the price which
          it would have been had an adjustment been made on the basis that the
          only shares of Common Stock so issued or sold were issued or sold upon
          the conversion or exchange of such Convertible Securities, and that
          they were issued or sold for the consideration actually received by
          the Corporation upon such conversion or exchange, plus the
          consideration, if any, actually received by the Corporation for the
          issue or sale of all of such Convertible Securities which shall have
          been converted or exchanged.

               (iii) RIGHTS AND OPTIONS.

                         (a)  In case the Corporation shall grant any rights or
          options to subscribe for, purchase or otherwise acquire Common Stock
          (other than pursuant to an incentive plan for employees adopted by a
          majority of the stockholders of the Corporation providing for the
          issuance of options to purchase no more than an aggregate of 500,000
          shares of Common Stock at



          a price of no less than 85% of fair market value), there shall be
          determined the price per share for which Common Stock is issuable
          upon the exercise of such rights or options, such determination to be
          made by dividing (1) the total amount, if any, received or receivable
          by the Corporation as consideration for the granting of such rights
          or options, plus the minimum aggregate amount of additional
          consideration payable to the Corporation upon the exercise of such
          rights or options, by (2) the maximum number of shares of Common
          Stock of the Corporation issuable upon the exercise of such rights
          or options.

                         (b)  If the price per share so determined shall be less
          than the applicable Conversion Price, then the granting of such rights
          or options shall be deemed to be an issue or sale for cash (as of the
          date of the granting of such rights or options) of such maximum number
          of shares of Common Stock at the price per share so determined,
          provided that, if such rights or options shall by their terms provide
          for an increase or increases or decrease or decreases, with the
          passage of time, in the amount of additional consideration payable to
          the Corporation upon the exercise thereof, the adjusted Conversion
          Price shall, forthwith upon any such increase or decrease becoming
          effective, be readjusted to reflect the same, and provided, further,
          that upon the expiration of such rights or options, if any thereof
          shall not have been exercised, the adjusted Conversion  Price shall
          forthwith be readjusted and thereafter be the price which it would
          have been had an adjustment been made on the basis that the only
          shares of Common Stock so issued or sold were those issued or sold
          upon the exercise of such rights or options and that they were issued
          or sold for the consideration actually received by the Corporation
          upon such exercise, plus the consideration, if any, actually received
          by the Corporation for the granting of all such rights or options,
          whether or not exercised.

               E.    SILICON ISOTOPE TRANSACTION.  In the event that on or
     before January 1, 2001 the Corporation sells or otherwise disposes of
     (including, without limitation, through lease, mortgage, joint venture,
     exchange, transfer or similar arrangements), or enters into a contract to
     sell or dispose of, all or a significant portion of the Silicon Isotope
     Business (a "Silicon Isotope Transaction"), the Corporation shall cause to
     be delivered to each Series A Holder, concurrently with the consummation of
     the Silicon Isotope Transaction, its pro rata share of the Exchange
     Interests and Transaction Cash Proceeds (as defined in Section 7C below).
     The Corporation shall not effect any Silicon Isotope Transaction unless
     prior to or simultaneous with the consummation thereof, the Silicon Isotope
     Successor Entity shall (i) deliver to each Series A Holder such holder's
     pro rata share of the Exchange Interests and Transaction Cash Proceeds;
     (ii) enter into a Registration Rights



     Agreement on terms substantially similar to that entered into between the
     Corporation and the Series A Holders, dated as of the Original Issue Date
     and (iii) provide the holders of Exchange Interests with equivalent rights
     to the rights set forth herein.

               F.    CERTAIN EVENTS.  If any event occurs of the type
     contemplated by the provisions of this Section 5 but not expressly provided
     for by such provisions, then the Board of Directors of the Corporation will
     make (i) an appropriate adjustment in the Conversion Price so as to protect
     the rights of the Series A Holders; provided that no such adjustment will
     increase the Conversion Price as otherwise determined pursuant to this
     Section 5 or decrease the number of shares of Conversion Stock issuable
     upon conversion of each share of Series A Stock and (ii) an appropriate
     adjustment in the terms of the Silicon Isotope Transaction so as to protect
     the rights of the Series A Holders.

               G.    NOTICES.

                         (i)  Immediately upon any adjustment of the Conversion
          Price, the Corporation will send written notice thereof to all Series
          A Holders.

                         (ii)  The Corporation will send written notice to all
          Series A Holders at least 20 days prior to the date (a) on which the
          Corporation closes its books or takes a record (1) with respect to any
          dividend or distribution upon Common Stock, (2) with respect to any
          PRO RATA subscription offer to holders of Common Stock, (3) for
          determining rights to vote on or approve any matter or (b) proposes to
          take any action on which the Series A Holders are entitled to vote
          pursuant to Section 3B or Section 4B.

                         (iii) In addition to the notice required under
          paragraph (ii) above, the Corporation will send written notice (the
          "Exchange Notice") to all Series A Holders at least 30 days prior to
          the date of any proposed Silicon Isotope Transaction setting forth in
          reasonable detail the material terms of the Silicon Isotope
          Transaction and the capitalization, financial condition, business plan
          and other material facts of the Silicon Isotope Successor Entity.

                         (iv)  All notices and other communications from the
          Corporation to a Series A Holder shall be mailed by first class
          registered or certified mail, postage prepaid, at such address as may
          have been furnished to the Corporation in writing by such holder, or,
          until an address is so



          furnished, to and at the address of the last holder who has so
          furnished an address to the Corporation.

               H.    CONVERTED OR REDEEMED SHARES.  Any shares of Series A
     Stock which are converted pursuant to this Section 5 or redeemed pursuant
     to Section 6 will be canceled and will not be reissued, sold or
     transferred.

               I.    INSUFFICIENT AUTHORIZED SHARES.  In the event at the time
     any Series A Holder requests conversion of any of such shares and the
     Corporation does not have a sufficient (for other events) number of shares
     of Common Stock authorized and unreserved to provide for conversion of all
     outstanding shares of Series A Stock, the Corporation shall give at least
     10 days prior written notice of such requested conversion to all other
     Series A Holders in order to enable such other holders to request
     conversion of their respective shares.  In the event that Series A Holders
     request conversion of shares or Series A Stock into a greater number of
     shares of Common Stock than the Corporation then has authorized and
     unreserved (for other events), the Corporation shall issue all of its
     authorized and unreserved (for other events) shares of Common Stock to such
     holders PRO RATA in accordance with the number of shares of Series A Stock
     of which each holder has requested conversion.  The unconverted balance of
     the shares of Series A Stock will remain as shares of Series A Stock until
     the Corporation has authorized a sufficient number of additional shares of
     Common Stock to provide for conversion of all shares of Series A Stock then
     outstanding.  In the event at the time any Series A Holder requests
     conversion of any of such shares and the Corporation does not have a
     sufficient number of shares of Common Stock authorized and reserved to
     provide for conversion of all outstanding shares of Series A Stock, the
     Corporation will promptly reserve such number of shares of authorized
     Common Stock as are sufficient to provide for conversion of all outstanding
     shares of Series A Stock, but if the Corporation does not have a sufficient
     number of shares of Common Stock authorized and unreserved (for other
     events) to reserve such number of shares, the Corporation will promptly
     reserve the authorized and unreserved (for other events) Common Stock and
     provide for such meetings to be held, and approvals to be solicited, as are
     necessary to authorize and reserve a sufficient number of shares of Common
     Stock to provide for conversion of all outstanding shares of Series A
     Stock.

     6.   OPTIONAL REDEMPTION.

               A.    After the Redemption Trigger Date (as defined in Section
     7C below) all or any part of the Series A Stock may be redeemed by the
     Corporation at its election at any time and from time to time, in the
     manner prescribed in this Section 6, provided that (i) in any redemption
     under this Section 6A the Corporation shall redeem no less than all
     outstanding shares of Series A Stock and



     (ii) the Corporation may not make any redemption unless and until the
     Corporation has registered under the Securities Act of 1933, as amended,
     either the issuance of the shares of Common Stock issuable on conversion
     of the Series A Stock or the resale of such shares by the holders thereof.

               B.    Before making any redemption, the Corporation shall mail
     by certified or registered mail, return receipt requested, to each record
     holder of any Series A Stock at the address shown on the Corporation's
     records, a written notice (a "Redemption Notice") stating: (i) the number
     of shares of Series A Stock  held of record by such holder which the
     Corporation proposes to redeem; (ii) the date (herein called the
     "Redemption Date") on which the Corporation proposes to pay the Redemption
     Price for the shares to be redeemed; (iii) the Redemption Price which under
     this Section 6 is to be paid for each share to be redeemed; (iv) the place
     at which the shares to be redeemed may be surrendered in exchange for the
     Redemption Price for such shares; and (v) the then current Conversion
     Price.  Upon the mailing of a Redemption, the Corporation shall become
     obligated to redeem the Series A Stock specified in such notice on the date
     specified in such notice as the Redemption Date.  Each Redemption Notice
     shall be mailed at least 30 days before the Redemption Date, provided that
     if the Corporation fails to pay the Redemption Price on such date (for a
     reason other than a holders' failure to deposit Series A Stock certificates
     pursuant to Section 6D below), the Redemption Date shall be the date on
     which the Corporation actually pays the Redemption Price.

               C.    The number of shares of Series A Stock to be redeemed from
     each holder thereof in repurchases under Section 6A shall be determined by
     multiplying the total number of shares of Series A Stock to be redeemed by
     a fraction, the numerator of which shall be the total number of shares of
     Series A Stock held by such holder and the denominator of which shall be
     the total number of shares of Series A Stock outstanding.

               D.    (i) For each share of Series A Stock which shall be
     redeemed by the Corporation at any time under Section 6A, the Corporation
     shall be obligated to pay to the holder of such share an amount in cash
     (herein called the "Redemption Price" for such share) equal to the
     Liquidation Value of such share.  The Corporation shall be obligated to pay
     on any Redemption Date on which the Corporation shall be required to redeem
     any Series A Stock  both the Redemption Price for each share and all
     dividends which shall have been declared on each share to and including the
     Redemption Date and which shall not previously have been paid.  Such
     payments which the Corporation shall be obligated to make on any Redemption
     Date shall be deemed to become "due" for all purposes of this Section 6
     regardless of whether the Corporation shall be able to legally permitted to
     make such payments on such Redemption Date.



                     (ii)     Each holder of Series A Stock  shall be entitled
          to receive on or at any time after any Redemption Date the full
          Redemption Price, plus declared but unpaid dividends, for each share
          of Series A Stock held by such holder which the Corporation shall be
          obligated to redeem on such Redemption Date upon surrender by such
          holder at the Corporation's principal office of the certificate
          representing such share duly endorsed in blank or accompanied by an
          appropriate form of assignment duly endorsed in blank.  After the
          payment by the Corporation in cash of the full Redemption Price for
          any Series A Stock, plus accrued unpaid dividends, all rights of the
          holder of such stock shall (whether or not the certificate
          representing such stock shall have been surrendered for cancellation)
          cease and terminate with respect to such stock.

     7.   MISCELLANEOUS.

               A.    REGISTRATION OF TRANSFER.  The Corporation will keep at
     its principal office a register for the registration of Series A Stock.
     Upon the surrender of any certificate representing Series A Stock at such
     place, the Corporation will, at the request of the record holder of such
     certificate, execute and deliver (at the Corporation's expense) a new
     certificate or certificates in exchange therefor representing in the
     aggregate the number of shares represented by the surrendered certificate.
     Each such new certificate will be registered in such name and will
     represent such number of shares as is requested by the holder of the
     surrendered certificate and will be substantially identical in form to the
     surrendered certificate.

               B.    REPLACEMENT.  Upon receipt of evidence reasonably
     satisfactory to the Corporation (an affidavit of the registered holder will
     be satisfactory) of the ownership and the loss, theft, destruction or
     mutilation of any certificate evidencing one or more shares of Series A
     Stock, and in the case of any such loss, theft or destruction, upon receipt
     of indemnity reasonably satisfactory to the Corporation, the Corporation
     will (at its expense) execute and deliver in lieu of such certificate a new
     certificate representing the number of shares represented by such lost,
     stolen, destroyed or mutilated certificate.

          C.   DEFINITIONS.  For purposes hereof:

               "APPLICABLE PERCENTAGE" shall mean the percentage that results
     from multiplying 25% by a fraction, the numerator of which is the number of
     shares of Series A Stock issued on, or within 30 days of, the date this
     Certificate is filed with the Secretary of State of the State of California
     and the denominator of which is 1,850,000.



               "COMMON STOCK" means the Common Stock of the Corporation, no par
     value per share, and includes all stock of any class or classes (however
     designated) of the Company, authorized upon the Original Issue Date or
     thereafter, the holders of which shall have the right, without limitation
     as to amount, either to all or to a share of the balance of current
     dividends and liquidating dividends after the payment of dividends and
     distributions on any shares entitled to preference, and the holders of
     which shall ordinarily, in the absence of contingencies, be entitled to
     vote for the election of a majority of directors of the Company (even
     though the right so to vote has been suspended by the happening of such a
     contingency).

               "CONVERSION PRICE" and "CONVERSION STOCK" shall have the meaning
     set forth in Sections 5B and 5A(i), respectively.

               "CORPORATION" shall have the meaning set forth in the first
     paragraph of this Certificate of Determination.

               "EXCHANGE INTERESTS" shall mean equity interests (whether in the
     form of stock, limited liability company interests, partnership interests,
     a percentage of profits and losses, or otherwise) entitling the holders
     thereof to the Applicable Percentage of the profits, votes and
     distributions of the Silicon Isotope Successor Entity and having
     substantially similar terms, preferences and other rights as the Series A
     Stock.

               "JUNIOR SECURITIES" means the Common Stock and any equity
     securities of any kind (but not including any debt securities convertible
     into equity securities) which the Corporation or any Subsidiary at any time
     issues or is authorized to issue other than the Series A Stock unless the
     terms of such security explicitly state that such security shall be senior
     to or on a par with the Series A Stock.

               "LIQUIDATION VALUE" of any share of Series A Stock as of any
     particular date will be $1.50.

               "ORIGINAL ISSUE DATE" means the date the Series A Stock is first
issued.

               "PERSON" and "PERSON" means an individual, a partnership, a
     corporation, a limited liability company, a trust, a joint venture, an
     unincorporated organization and a government or any department or agency
     thereof.

               "REDEMPTION TRIGGER DATE" shall mean the business day immediately
     following the thirtieth consecutive trading day that the average Closing
     Price during such trading days (or, if no closing price is reported, the
     average of the bid and ask



     prices) of the shares of Common Stock was above $8.00 per share (which
     minimum price shall be proportionately adjusted for stock splits, stock
     dividends, reverse stock splits and any other subdivision or combination
     of the Common Stock.

               "SERIES A HOLDER" shall mean a registered holder of Series A
     Stock.

               "SERIES A STOCK" shall have the meaning set forth in Section 1.

               "SILICON ISOTOPE BUSINESS" shall mean all the assets and business
     of the Corporation relating to the development, production, use or sale of
     isotopes of silicon metal and related products, including without
     limitation all related patents, know-how, procedures, business plans,
     customer lists and other intellectual property.

               "SILICON ISOTOPE SUCCESSOR ENTITY" shall mean the Person or other
     entity that will conduct the Silicon Isotope Business upon the consummation
     of the Silicon Isotope Transaction.

               "SUBSIDIARY" means any corporation of which the shares of stock
     having a majority of the general voting power in electing the board of
     directors are, at the time as of which any determination is being made,
     owned by the Corporation either directly or indirectly through
     Subsidiaries.

               "TRANSACTION CASH PROCEEDS" shall mean the Applicable Percentage
     of the cash paid or payable in connection with a Silicone Isotope
     Transaction

               D.    AMENDMENT AND WAIVER.  No amendment, modification or
     waiver will be binding or effective with respect to any provision hereof
     without the prior approval of a majority of the outstanding Shares of
     Series A Stock; provided notwithstanding Section 3.B above that no such
     action will change or affect (a) the Conversion Price of the Series A Stock
     or the number of shares or the class of stock into which the Series A Stock
     is convertible, (b) the Liquidation Value of the Series A Stock, or (c) the
     amount of cash, securities or other property receivable or to be received
     by the Series A Holders.

               E.    GENERALLY ACCEPTED ACCOUNTING PRINCIPLES.  When any
     accounting determination or calculation is required to be made, such
     determination or calculation (unless otherwise provided) will be made in
     accordance with generally accepted accounting principles, consistently
     applied, except that if because of a change in generally accepted
     accounting principles the Corporation would have to alter a previously
     utilized accounting method or policy in order to remain in compliance with
     generally accepted accounting principles, such determination or



     calculation will continue to be made in accordance with the Corporation's
     previous accounting methods and policies unless the Corporation has
     obtained the prior written consent of the holders of a majority of the
     Series A Stock then outstanding.

3.   The number of authorized shares of Preferred Stock of the Corporation is
10,000,000, and the number of shares of Series A Stock, none of which has
been issued, is 1,850,000.

     IN WITNESS WHEREOF, the undersigned officers of the Corporation have
executed this Amended and Restated Certificate this _____ day of July, 1999.


                                       ISONICS CORPORATION


                                       By:
                                          -------------------------------
                                          James E. Alexander, President


                                       By:
                                          -------------------------------
                                          Brantley J. Halstead, Secretary



                              VERIFICATION

     The undersigned, James E. Alexander and Brantley J. Halstead, the
President and Secretary, respectively, of Isonics Corporation, each declares
under penalty of perjury that the matters set out in the foregoing Amended
and Restated Certificate are true of his own knowledge.  Executed at Golden,
Colorado, on this _____ day of July, 1999.


                                       -----------------------------
                                       James E. Alexander


                                       -----------------------------
                                       Brantley J. Halstead