EXHIBIT 99.1

Contacts:

Jeremy Price                                           Fredda Malkoff
Manager, Investor Relations                            Account Director
BioMarin Pharmaceutical Inc.                           Feinstein Kean Healthcare
(415) 884-6777                                         (617) 577-8110
jprice@biomarinpharm.com                               fmalkoff@fkhealth.com

For Immediate Release:

              BioMarin Appoints New CFO and Three New Board Members

Novato, CA, July 15th, 2002 - BioMarin  Pharmaceutical  Inc. (Nasdaq and SWX New
Market:  BMRN)  today  announced  that it has  appointed  a new Chief  Financial
Officer  and  elected  three new  members to its Board of  Directors.  Effective
August 1, 2002,  Louis Drapeau will join BioMarin as Vice  President,  Finance &
Chief Financial Officer, and Secretary.  Effective immediately, Franz Cristiani,
retired Partner of Arthur Andersen,  LLP, Elaine Heron, PhD, Chairman and CEO of
Picoliter Inc., and Vijay Samant, President and CEO of Vical Incorporated,  have
been elected to the Board.

Fredric  D.  Price,  BioMarin's  Chairman  and Chief  Executive  Officer,  said,
"Strengthening  our  management  team has been one of BioMarin's  most important
initiatives this year. The addition of Lou Drapeau, who brings over thirty years
of  senior  financial  management  experience,  will  enable  us to build on the
valuable work that our `acting CFO',  Franz  Cristiani,  has provided  since the
beginning of this year. Franz's appointment to our Board of Directors,  where he
will serve as  chairperson of the audit  committee,  will be invaluable to us as
the business moves forward to meet our clinical and commercial goals."

Mr. Price added,  "We are also pleased to welcome  Elaine Heron and Vijay Samant
to  our  Board  of  Directors.   Their  vast   experience   in  leading   large,
entrepreneurial,  and technology-driven  life science companies will add a fresh
perspective  to the Board.  With the recent  creation  of our  Science  Advisory
Board,  we now have the management,  board,  and advisory teams in place to help
guide us as we  continue  our  efforts to advance  our broad  pipeline  of novel
enzyme  therapeutics  through  the  clinic  and  into  the  commercial  stage of
development."

These three new Board appointments,  combined with Grant Denison's  resignation,
increased  the size of the  Board  from five to seven  members,  six of whom are
`outside' directors (not employees of the Company).



Summary biographies of Mr. Drapeau, Mr. Cristiani, Dr. Heron, and Mr. Samant are
available on the following pages.

BioMarin  specializes in the  development and  commercialization  of therapeutic
enzyme products to treat serious, life-threatening diseases and conditions.

This  press  release  contains  forward-looking  statements  about the  business
prospects of BioMarin  Pharmaceutical Inc. These forward-looking  statements are
predictions  and involve risks and  uncertainties  such that actual  results may
differ materially from these statements. Results may differ materially depending
on the  progress  of  BioMarin's  product  programs,  the actual  results of the
current  and  planned  clinical  trials,  actions  of  regulatory   authorities,
availability  of  capital,  future  actions  in the  pharmaceutical  market  and
developments by competitors,  and those factors  detailed in BioMarin's  filings
with the  Securities  and Exchange  Commission  such as 10Q, 10K and 8K reports.
Stockholders   are  urged  not  to  place  undue  reliance  on   forward-looking
statements,  which  speak  only as of the  date  hereof.  BioMarin  is  under no
obligation,  and  expressly  disclaims  any  obligation,  to update or alter any
forward-looking statement, whether as a result of new information, future events
or otherwise.

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Summary biographies

Louis Drapeau,  Vice President,  Finance & CFO, and Secretary - Prior to joining
BioMarin,  Mr. Drapeau spent 31 years at Arthur Andersen LLP, including fourteen
years as Managing  Partner of Assurance and Consulting for Northern  California,
supervising  more than 400  professionals.  His skill set includes  working with
businesses  that  have a strong  international  focus  and he also has  in-depth
capital market experience as well as an extensive  knowledge of `best practices'
in the areas of financial controls and administration.  From 1966 to 1969 he was
a Naval Officer serving with U.S. Naval Civil  Engineering  Corps principally in
Seabee units in the Republic of Vietnam.  He holds an MBA in Finance and a BS in
Mechanical  Engineering from Stanford  University,  and he is a Certified Public
Accountant.

Franz  Cristiani,  Member of BioMarin's  Board of Directors - Mr.  Cristiani has
served as BioMarin's  `acting CFO' since January 2002. From 1964 to 1999, he was
with Arthur  Andersen,  as partner since 1976, with clients in high  technology,
life sciences, manufacturing, mining, forest products, distribution,  publishing
and food  products  industries.  He  specialized  in  public  companies  and had
extensive hands-on  experience with Securities  Exchange  Commission filings and
financings. He holds a BA from San Francisco State University and is a Certified
Public Accountant.

Elaine Heron,  PhD, Member of BioMarin's Board of Directors - Dr. Heron has more
than 25 years of senior  management  experience in high  technology life science
business  management.  Prior to her  present  position  as  Chairman  and CEO of
Picoliter Inc., she spent six years in increasingly responsible positions at the
Applied  Biosystems  Group of Applera  Corporation,  including stints as General
Manager and Vice President of Sales and Marketing.  At  Affymetrix,  Inc.,  from
1995 to 1996 she was Vice President,  Marketing. Dr. Heron has a BS in Chemistry
with Highest Distinction and a PhD in Analytical Biochemistry,  both from Purdue
University, and an MBA from Pepperdine University.

Vijay Samant,  Member of BioMarin's Board of Directors - Mr. Samant has 23 years
of U.S.  and  international  pharmaceuticals  experience  in the areas of sales,
marketing,  operations and business development. In 2001, Mr. Samant assumed his
present  position as President  and CEO of Vical  Incorporated.  From 1998 until
2001, he was with Merck Inc.,  most recently as Chief Operating  Officer,  Merck
Vaccine Division.  Previously, he held the positions of Vice President,  Vaccine
Operations and Vice President, Business Affairs, also at Merck Vaccine Division.
He holds an MBA  from  the  Sloan  School  of  Management  at the  Massachusetts
Institute of Technology, an MS in Chemical Engineering from Columbia University,
and a BS in Chemical Engineering from the University of Bombay, India.


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