Exhibit 99.2

The Audited Financial Statements of Glyko Biomedical Ltd. as of and for the
Year Ended December 31, 2001.


                    Report of Independent Public Accountants*



To the Shareholders of Glyko Biomedical Ltd.:



We have audited the  accompanying  balance  sheets of Glyko  Biomedical  Ltd. (a
Canadian company) as of December 31, 2001 and 2000 and the related statements of
operations, shareholders' equity and cash flows for the years ended December 31,
2001, 2000 and 1999. These financial  statements are the  responsibility  of the
company's  management.  Our  responsibility  is to  express  an opinion on these
financial statements based on our audits.

We conducted our audits in accordance with auditing standards generally accepted
in the United States. Those standards require that we plan and perform the audit
to obtain reasonable  assurance about whether the financial  statements are free
of material misstatement. An audit includes examining, on a test basis, evidence
supporting  the amounts and  disclosures in the financial  statements.  An audit
also includes assessing the accounting principles used and significant estimates
made by  management,  as well as  evaluating  the  overall  financial  statement
presentation.  We believe  that our audits  provide a  reasonable  basis for our
opinion.

In our opinion,  the financial  statements  referred to above present fairly, in
all material  respects,  the financial  position of Glyko  Biomedical Ltd. as of
December 31, 2001 and 2000, and the results of its operations and its cash flows
for the  years  ended  December  31,  2001,  2000  and 1999 in  conformity  with
accounting principles generally accepted in the United States.



                             /s/ ARTHUR ANDERSEN LLP

San Francisco California
February 21, 2002

*  This  report is a copy  of a previously issued Arthur Andersen LLP report and
   this report has not been reissued by Arthur Andersen LLP.






                                       GLYKO BIOMEDICAL LTD.
                                          BALANCE SHEETS
                                         (In U.S. dollars)
                                                                                
                                                                December 31,              December 31,
                                                                    2001                      2000
                                                            ---------------------     ---------------------
                                                                (Unaudited)
Assets
Current assets:
    Cash and cash equivalents                                        $ 2,444,424                 $ 408,133
    Short-term investments                                                     -                 1,397,217
    Interest receivable                                                        -                    29,876
                                                            --------------------     ---------------------
      Total current assets                                             2,444,424                 1,835,226
Investment in BioMarin Pharmaceutical Inc.                            34,857,531                19,020,505
                                                            --------------------     ---------------------
      Total assets                                                  $ 37,301,955              $ 20,855,731
                                                            =====================     =====================

Liabilities and Shareholders' Equity
Current liabilities:
    Accrued liabilities                                                $ 461,327                 $ 315,438
                                                            --------------------     ---------------------
      Total current liabilities                                          461,327                   315,438
                                                            ---------------------     ---------------------

Shareholders' equity:
    Common shares, no par value, unlimited shares
      authorized, 34,352,823 shares issued and
      outstanding at both December 31, 2001 and
      December 31, 2000.                                              22,535,096                22,535,096
    Additional paid-in capital                                        70,154,983                39,561,634
    Common share warrants                                                      -                     2,934
    Note receivable from shareholder                                           -                  (804,771)
    Accumulated deficit                                              (55,849,451)              (40,754,600)
                                                            --------------------     ---------------------
      Total shareholders' equity                                      36,840,628                20,540,293
                                                            --------------------     ---------------------
      Total liabilities and shareholders' equity                    $ 37,301,955              $ 20,855,731
                                                            =====================     =====================



                         The accompanying notes are an integral part of these statements.



                             Glyko Biomedical Ltd.
  Statements of Operations for the Years Ended December 31, 2001, 2000 and 1999
                               (In U.S. dollars)


                                             Year Ended December 31
                                      2001            2000           1999
                                   ---------       ----------      ---------

Expenses:
  General and administrative       $ 462,022       $ 388,373       $ 199,302
                                   ---------       ---------       ---------
    Total expenses                   462,022         388,373         199,302
                                   ---------       ---------       ---------

Loss from operations                (462,022)       (388,373)       (199,302)
Equity in loss of BioMarin
 Pharmaceutical Inc.             (14,678,250)    (11,312,285)     (9,999,581)
Interest income                       45,421          65,317         159,352
                                   ---------       ---------       ---------
Net loss                        $(15,094,851)   $(11,635,341)   $(10,039,531)
                                   =========       =========       =========

Net loss per common share,
 basic and diluted              $     (0.44)    $     (0.34)    $      (0.32)
                                   =========       =========       =========

Weighted average common shares
  outstanding, basic and diluted 34,352,823      33,915,043       31,065,575
                                 ==========      ==========       ==========



        The accompanying notes are an integral part of these statements.



                             Glyko Biomedical Ltd.
    Statements of Stockholders' Equity for the Year Ended December 31, 2001
                               (In U.S. dollars)



                                                                                                  
                                       Common Share                     Common Share   Note Receivable    Accumulated
                                   Shares    Amount    Paid In Capital   Warrants      From Shareholder    Deficit        Total
                                   ------    ------    ---------------  ------------   ----------------   -----------     -----
Balance at December 31, 1998   28,020,234  $ 17,963,167 $ 11,222,691     $ 547,285        $(721,971)     $(19,079,728) $ 9,931,444

Net loss for the year                  -            -           -              -                -         (10,039,531) (10,039,531)

Exercise of stock options         280,560       161,633         -              -                -                   -      161,633

Exercise of stock warrants      3,534,528     2,647,669         -         (397,879)             -                   -    2,249,790

Reclassification of interest on note receivable
  from shareholder                      -             -       27,600             -          (27,600)                -            -

Additional paid-in capital resulting from the
  sale of common stock by BioMarin Pharmaceutical
  Inc.                                  -             -   26,814,190             -                -                 -   26,814,190

                               ----------  ------------ ------------     ---------       -----------    --------------------------
Balance at December 31, 1999   31,835,322  $ 20,772,469 $ 38,064,481     $ 149,406       $ (749,571)    $ (29,119,259)$ 29,117,526
                               ==========  ============ ============     =========       ===========    ==========================

Net loss for the year                   -             -            -             -                -       (11,635,341) (11,635,341)

Exercise of common share options  299,500        269,092           -             -                -                 -      269,092

Exercise of common share
  warrants                      2,218,001      1,493,535      17,609      (149,406)               -                 -    1,361,738

Interest accrued on note receivable
  from shareholder                      -              -      55,200             -          (52,266)                -        2,934

Additional paid-in capital from the
  sale of common stock by BioMarin
  Pharmaceutical Inc.                   -              -   1,424,344             -                -                 -    1,424,344

                               ----------   ------------------------    ----------       -----------    --------------------------
Balance at December 31, 2000   34,352,823   $ 22,535,096 $39,561,634    $        -       $ (801,837)    $ (40,754,600)$ 20,540,293
                               ==========   ============ ===========    ==========       ===========    ==========================

Net loss for the year                   -              -           -                                      (15,094,851) (15,094,851)

Interest accrued on note receivable from shareholder
  and other                             -              -      78,073             -          (78,073)                -

Repayment of note receivable from
  shareholder                           -              -           -             -          879,910                 -      879,910

Additional paid-in capital from the
  sale of common stock by BioMarin
  Pharmaceutical Inc.                   -              -  30,515,276             -                -                 -   30,515,276

                               ----------  -------------------------    ----------        ---------     -------------- -----------
Balance at December 31, 2001   34,352,823  $  22,535,096 $70,154,983    $        -        $       -     $ (55,849,451) $36,840,628
                               ==========  ============= ===========    ==========        =========     ============== ===========




        The accompanying notes are in integral part of these statements





                             Glyko Biomedical Ltd.
 Statements of Cash Flows for the Years Ended December 31, 2001, 2000 and 1999
                               (In U.S. dollars)

                                                                                               


                                                                                 Year Ended December 31,
                                                                       2001              2000                1999
                                                                ----------------    ---------------     --------------
Cash flows from operating activities:
     Net loss                                                    $ (15,094,851)      $ (11,635,341)      $(10,039,531)
Adjustments to reconcile net loss to net cash
       used in operating activities:
     Equity in loss of BioMarin Pharmaceutical Inc.                 14,678,250          11,312,285          9,999,581
     Changes in assets and liabilities:
       Interest receivable                                              29,876             (29,876)                 -
       Accrued liabilities                                             145,889             (50,131)            15,461
                                                                ----------------    ---------------     --------------
     Total adjustments                                              14,854,015          11,232,278         10,015,042
                                                                ----------------    ---------------     --------------
       Net cash used in operating activities                          (240,836)           (403,063)           (24,489)
                                                                ----------------    ---------------     --------------
Cash flows from investing activities:
     Investment in BioMarin Pharmaceutical Inc.                              -                   -         (4,419,110)
     Sale (Purchase) of short-term investments                       1,397,217          (1,397,217)                 -
                                                                ----------------    ---------------     --------------
       Net cash provided by (used in) investing activities           1,397,217          (1,397,217)        (4,419,110)
                                                                ----------------    ---------------     --------------
Cash flows from financing activities:
     Proceeds from exercise of common share options and
       warrants                                                              -           1,633,765          2,350,423
     Repayment of note receivable from shareholder                     879,910                   -            100,000
                                                                ----------------    ---------------     --------------
       Net cash provided by financing activities                       879,910           1,633,765          2,450,423
                                                                ----------------    ---------------     --------------
Net increase (decrease) in cash and cash equivalents                 2,036,291            (166,515)        (1,993,176)
Cash and cash equivalents, beginning of period                         408,133             574,648          2,567,824
                                                                ----------------    ---------------     --------------
Cash and cash equivalents, end of period                           $ 2,444,424           $ 408,133          $ 574,648
                                                                ================    ===============     ==============







        The accompanying notes are an integral part of these statements.





                              GLYKO BIOMEDICAL LTD.
                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

1.   The Company and Description of the Business

Glyko  Biomedical  Ltd.  (the Company or GBL) is a Canadian  company,  which was
established  in 1992 to acquire all of the  outstanding  capital stock of Glyko,
Inc., a Delaware  corporation.  Since its inception in October 1990, Glyko, Inc.
engaged in research and  development of new techniques to analyze and manipulate
carbohydrates for research,  diagnostic and pharmaceutical purposes. Glyko, Inc.
developed a line of analytic instrumentation laboratory products that include an
imaging system, analysis software and chemical analysis kits.

In October 1996, GBL formed BioMarin Pharmaceutical Inc. (BioMarin),  a Delaware
corporation in the development  stage,  to develop the Company's  pharmaceutical
products. BioMarin began business on March 21, 1997 (inception) and subsequently
issued  1.5  million  shares  of  common  stock  to GBL  for  $1.5  million.  As
consideration for a certain license  agreement dated June 1997,  BioMarin issued
GBL 7 million  shares of  BioMarin  common  stock.  Beginning  in October  1997,
BioMarin raised capital from third parties. As of December 31, 1997, the Company
began  recording its share of BioMarin's net loss utilizing the equity method of
accounting.  On June 30, 1998,  GBL made an additional $1 million  investment in
BioMarin.

On October 7, 1998, GBL sold to BioMarin 100% of the  outstanding  capital stock
of Glyko,  Inc. in exchange for 2,259,039 shares of BioMarin's  common stock. In
addition,  BioMarin agreed to assume options,  previously issued to employees of
Glyko, Inc., to purchase up to 585,969 shares of GBL's common stock (exercisable
into 255,540 shares of BioMarin common stock) and BioMarin paid $500 in cash.

On April 13, 1999, the Company entered into a convertible  note arrangement with
BioMarin in the amount of $4.3  million,  as part of a $26  million  convertible
note  financing.  This note plus  accrued  interest was  converted  into 441,911
shares of BioMarin  common  stock  concurrent  with  BioMarin's  initial  public
offering on July 23, 1999.

In May 2001,  BioMarin  completed  two  private  placements  of its  securities,
raising  total net proceeds of  approximately  $42.5  million.  On May 16, 2001,
BioMarin  sold  4,763,712  shares of common stock at $9.45 per share and, for no
additional consideration,  issued three-year warrants to purchase 714,554 shares
of common stock at an exercise price of $13.10 per share. On May 17, 2001 a fund
managed  by Acqua  Wellington  purchased  105,821  shares  of  common  stock and
received  warrants to purchase  15,873  shares of common stock on the same price
and terms as the May 16, 2001 transaction.

In August 2001, BioMarin signed an amended agreement with Acqua Wellington North
American  Equities  Fund Ltd.  (Acqua  Wellington)  for an equity  investment in
BioMarin.  The  agreement  allows  for  the  purchase  of  up to  $27.7  million
(approximately  2,500,000  shares).  Under the terms of the agreement,  BioMarin
will have the option to request that Acqua Wellington invest in BioMarin through
sales of  registered  common  stock at a small  discount  to market  price.  The
maximum  amount  that  BioMarin  may  request  to be  bought in any one month is
dependent  upon the market price of the stock (or an amount that can be mutually
agreed-upon  by both  parties)  and is  referred  to as the "Draw Down  Amount."
Subject to certain  conditions,  Acqua  Wellington is obligated to purchase this
amount if  requested to do so by BioMarin.  In  addition,  BioMarin  may, at its
discretion,  grant  a  "Call  Option"  to  Acqua  Wellington  for an  additional
investment in an amount up to the "Draw Down Amount" which Acqua  Wellington may
or may not choose to exercise. During 2001, Acqua Wellington purchased 1,344,194
shares for $13.5  million  ($13.2  million  net of issuance  costs).  Under this
agreement, Acqua Wellington may also purchase stock and receive similar terms of
any other equity financing by the BioMarin.

On October 31, 2001,  BioMarin  purchased from IBEX Technologies Inc. (TSE: IBT)
and its subsidiaries the intellectual  property and other assets associated with
the IBEX therapeutic enzyme drug products (including NeutralaseTM and Phenylase)
for $10.4 million, consisting of $2 million in cash and $8.4 million in BioMarin
common stock at $10.218 per share (814,647  shares).  The purchase also includes
up to  approximately  $9.5  million  in  contingency  payments  upon  regulatory
approval of Neutralase and Phenylase,  provided that approval occurs within five
years.   The  transaction  was  accounted  for  using  the  purchase  method  of
accounting.  All of the purchase  price plus related  expenses are  reflected on
BioMarin's  consolidated  statements of  operations  as in-process  research and
development expenses totaling $11.6 million.






                              GLYKO BIOMEDICAL LTD.
                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS


On December 13, 2001,  BioMarin completed a public offering of its common stock.
In the offering,  BioMarin sold 8,050,000 shares,  including 1,050,000 shares to
cover over-allotments,  at a price to the public of $12.00 per share, or a total
offering price of $96.6 million. The net proceeds to BioMarin were approximately
$90.4 million.

In February 2002, BioMarin decided to close the carbohydrate analytical business
portion  of  Glyko,  Inc.,  which  provided  all  of  Glyko,   Inc.'s  revenues.
Accordingly,  BioMarin recorded a Glyko, Inc. closure expense of $7.9 million in
the 2001 consolidated statements of operations.  This charge consisted primarily
of an impairment  reserve against the unamortized  balance of goodwill and other
intangible  assets related to the acquisition of Glyko, Inc. The majority of the
Glyko,  Inc.  employees will be incorporated into the BioMarin business and such
employees will continue to provide necessary  analytic and diagnostic support to
BioMarin's therapeutic products

As a result of BioMarin's IPO,  concurrent with the conversion of the notes from
GBL and  other  noteholders,  the  sale by  BioMarin  of  common  stock to Acqua
Wellington,  the sales by BioMarin of common stock in the private placements and
a follow-on  offering,  the exercise of BioMarin  stock  options and warrants by
third parties, and the purchase of IBEX Technologies  intellectual  property and
other assets  associated with the IBEX therapeutic  enzyme drug products,  GBL's
ownership of BioMarin's outstanding stock on December 31, 2001 was 21.7%.

Since our inception,  we have incurred a cumulative deficit of $55.8 million and
we expect to continue to incur  losses due to our share of  BioMarin's  net loss
resulting from the ongoing research and development of BioMarin's pharmaceutical
product  candidates  through the second  quarter of 2002 (up until the  proposed
purchase  of us by  BioMarin  discussed  in Footnote  8).  Accordingly,  without
further investment in other companies or technologies,  management believes that
GBL has  sufficient  cash to  sustain  planned  operations  for the  foreseeable
future.

2.      Summary of Significant Accounting Policies

The accompanying  financial  statements and related footnotes have been prepared
in conformity with U.S.  generally  accepted  accounting  principles  using U.S.
dollars as  substantially  all of the Company's  operations  were located in the
United States.  The financial  statements include the accounts and operations of
the Company and Glyko,  Inc for the period from January 1, 1998 through  October
7,  1998,  the date of the sale of  Glyko,  Inc.  All  significant  intercompany
accounts and transactions have been eliminated.  BioMarin's consolidated results
of operations have been reported in the accompanying  financial statements based
on the equity method of  accounting.  The results of operations of BioMarin have
been reported in the Company's financial statements for the years ended December
31, 2001, 2000 and 1999, based on the equity method of accounting. Subsequent to
October 7, 1998, the results of operations of Glyko, Inc. have been consolidated
into the results of operations of BioMarin.

        Use of Estimates:

The  preparation of the Company's  financial  statements in conformity with U.S.
generally accepted  accounting  principles  requires  management to make certain
estimates  and  assumptions  that  effect  the  reported  amounts  of assets and
liabilities and the disclosure of contingent assets and liabilities at the dates
of the financial  statements  and the reported  amounts of revenues and expenses
during the reporting periods. Actual results could differ from those estimates.

       Cash and Cash Equivalents:

Cash and cash  equivalents  consist  of amounts  held with banks and  short-term
investments with original maturities of less than three months when purchased.

       Short-term Investments:

GBL records its investments as  held-to-maturity.  Short-term  investments  were
recorded at cost at December 31, 2000,  which  approximated  fair market  value.
These securities were comprised  mainly of A1/P1 grade  commercial  paper. As of
December 31, 2001, there are no short-term investments.



                              GLYKO BIOMEDICAL LTD.
                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

       Sale of Glyko, Inc. and Investment in BioMarin Pharmaceutical Inc.:

BioMarin  acquired  Glyko,  Inc. from GBL through the exchange of BioMarin stock
for Glyko,  Inc.  stock and  accounted for the  acquisition  based upon the fair
market  value of the  BioMarin  stock  issued.  In  consolidating  Glyko,  Inc.,
BioMarin recorded intangible assets,  including goodwill, to the extent that the
fair market  value of the stock  issued  exceeded  the fair market  value of the
tangible  assets  of  Glyko,  Inc.  acquired.  However,  as  GBL  exchanged  one
investment  for  another,  it  recorded  the stock of  BioMarin  received at the
historical  cost  basis  of its  investment  in  Glyko.  GBL  accounts  for  its
investment in BioMarin using the equity method of accounting.  However, GBL does
not  record  its  share  of the  losses  recorded  by  BioMarin  related  to the
amortization of intangible assets recorded in connection with the acquisition of
Glyko. For the years ended December 31, 2000 and 2001, BioMarin recoded a charge
to operations for the  amortization of goodwill and other  intangible  assets of
$1.6 million and $1.2 million,  respectively. In February 2002, BioMarin decided
to close the  carbohydrate  analytical  business  portion of Glyko,  Inc., which
provided all of Glyko, Inc.'s revenues. Accordingly,  BioMarin recorded a Glyko,
Inc.  closure  expense of $7.9 million in the 2001  consolidated  statements  of
operations. This charge consisted primarily of an impairment reserve against the
unamortized  balance of  goodwill  and other  intangible  assets  related to the
acquisition of Glyko, Inc.

In  addition,  to the extent  that the  issuance  of stock by  BioMarin to third
parties  results  in a change in the  Company's  ownership  interest  in the net
assets of BioMarin,  the Company reflects this change in its paid-in capital and
its investment in BioMarin.  The Company  recorded an increase to its additional
paid-in capital of  approximately  $30.6 million and $1.4 million as a result of
its share in BioMarin funds raised by third parties for the years ended December
31, 2001 and 2000, respectively.

       Foreign Exchange:

As  substantially  all of the  Company's  operations  are  located in the United
States, the Company has adopted the U.S. dollar as its functional  currency.  In
accordance  with  Statement of Financial  Accounting  Standard No. 52,  "Foreign
Currency  Translation",  any  assets  and  liabilities  denominated  in  foreign
currency  are  translated  into U.S.  dollars at the  current  rate of  exchange
existing at year end and revenues and  expenses  are  translated  at the average
monthly exchange rates.  Transaction gains and losses included in the statements
of operations are not material.

       Net Loss per Share:

Potentially dilutive securities outstanding at December 31, 2001, 2000 and 1999,
respectively,  include  options for the  purchase  of 45,000,  7,750 and 291,000
shares of common  stock and  warrants  for the  purchase  of zero,  zero and 2.2
million  shares of common stock.  These  securities  were not  considered in the
computation   of  dilutive   loss  per  share  because  their  effect  would  be
anti-dilutive for the years ended December 31, 2001, 2000 and 1999.

3.      New Accounting Pronouncements

       SFAS 141 and 142:

On June 29, 2001, the Financial  Accounting  Standards Board (FASB) approved for
issuance  Statement of Financial  Accounting  Standards (SFAS) No. 141, Business
Combinations, and SFAS No. 142, Goodwill and Intangible Assets. Major provisions
of these Statements are as follows:  all business  combinations  initiated after
June 30,  2001  must use the  purchase  method of  accounting;  the  pooling  of
interests method of accounting is prohibited  except for transactions  initiated
before July 1, 2001;  intangible assets acquired in a business  combination must
be recorded  separately  from goodwill if they arise from  contractual  or other
legal  rights  or are  separable  from  the  acquired  entity  and can be  sold,
transferred,  licensed, rented or exchanged, either individually or as part of a
related contract,  asset or liability; all acquired goodwill must be assigned to
reporting  units for  purposes of  impairment  testing  and  segment  reporting;
effective January 1, 2002,  goodwill and intangible assets with indefinite lives
will not be amortized but will be tested for  impairment  annually  using a fair
value  approach,  except in  certain  circumstances,  and  whenever  there is an
impairment  indicator;  other  intangible  assets will continue to be valued and
amortized  over their  estimated  lives;  in-process  research  and  development
acquired in business  combinations  will continue to be written off immediately;
goodwill arising between June 29, 2001 and December 31, 2001 will not be subject
to  amortization.  Management  is  currently  assessing  the  impact  of the new
standards. The adoption of SFAS No. 142 in January 2002 will not have a material
impact on the Company's financial statements.

       SFAS 143:

In June 2001, the FASB approved for issuance SFAS No. 143, "Accounting for Asset
Retirement  Obligations."  SFAS  No.  143  requires  that  the  fair  value of a
liability  for an asset  retirement  obligation  be  recognized in the period in
which  it is  incurred  and  that  the  associated  asset  retirement  costs  be
capitalized as part of the carrying value of the related  long-lived asset. SFAS
No. 143 will be effective  January 1, 2002 for GBL.  Management  does not expect
this standard to have a material impact on GBL's  financial  position or results
of operations.



                              GLYKO BIOMEDICAL LTD.
                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

       SFAS 144:

In August 2001, the FASB approved for issuance SFAS No. 144, "Accounting for the
Impairment  or  Disposal  of  Long-Lived  Assets."  SFAS No.  144  broadens  the
presentation  of  discontinued  operations  to  include  more  transactions  and
eliminates the need to accrue for future operating  losses.  Additionally,  SFAS
No. 144 prohibits the retroactive  classification of assets as held for sale and
requires  revisions  to  the  depreciable  lives  of  long-lived  assets  to  be
abandoned.  SFAS No. 144 will be effective  January 1, 2002 for GBL.  Management
does not  expect  this  standard  to have a material  impact on GBL's  financial
position or results of operations.  During the year ended December 31, 1999, the
Company adopted SFAS No. 131,  "Disclosures  about Segments of an Enterprise and
Related  Information".  The  Company  concluded  that it has only one  operating
segment.

4.     Income Taxes

In connection with the sale of Glyko,  Inc., the U.S.  federal and state net tax
operating  loss   carryforwards  and  the  related  valuation   allowances  were
consolidated into the financial statements of BioMarin.

At December 31,  2001,  the Company has net  operating  loss  carryforwards  for
Canadian  income tax  purposes of  approximately  $1.7  million,  which began to
expire in 2000.  A valuation  allowance is placed on the net deferred tax assets
to reduce them to an assumed net realizable value of zero.

5.        Note Receivable

In November 1998, per the terms of the BioMarin  acquisition of Glyko, Inc., GBL
loaned $712,261 to an officer of the Company to exercise expiring stock options.
The loan  matured in May 2001 and the note plus  accrued  interest was repaid in
the third quarter of 2001.

6.        Common Share Option Plan

The Company  has a common  share  option plan (the Plan) under which  options to
purchase  common stock may be granted by the Board of  Directors  to  directors,
officers, consultants and key employees at not less than fair market value, less
any permissible discounts,  on the date of grant. . Options are exercisable over
a number of years  specified at the time of the grant,  which cannot  exceed ten
years. The maximum aggregate number of shares that may be granted and sold under
the Plan is 3 million shares.

The  Company  accounts  for the Plan  such  that no  compensation  cost has been
recognized, except for options granted to consultants, because, under the Option
Plan, the option  exercise price equals the market value of stock on the date of
grant.  In general,  the Plan options vest over 48 months and all options expire
after 5 years or 90 days after employee termination.





                              GLYKO BIOMEDICAL LTD.
                          NOTES TO FINANCIAL STATEMENTS

Had  compensation  cost  for the  Plan  been  determined  consistent  with  FASB
Statement  No. 123,  the  Company's  net loss would have been  increased  to the
following pro forma amounts:


                                                                         


                                              2001                  2000                 1999
                                              ----                  ----                 ----
Net loss              As reported         $(15,094,851)        $(11,635,341)         $(10,039,531)
                      Pro forma            (15,264,594)
                                                                (11,829,182)          (10,324,435)

Net loss per          As reported            $(0.44)              $(0.34)               $(0.32)
  common share        Pro forma               (0.44)               (0.35)                (0.33)


The fair value of each option  granted is  estimated  on the date of grant using
the  Black-Scholes  option  pricing  model with the  following  weighted-average
assumptions used for grants in 2001 and 2000,  respectively:  risk-free weighted
average  interest  rates  of 4.9%  and  5.8%;  expected  dividend  yield of zero
percent; expected life of 4 years for the Plans' options; expected volatility of
78% and 193%.

Because the Statement  123 method of accounting  has not been applied to options
granted prior to January 1, 1995, the resulting pro forma  compensation cost may
not be representative of that to be expected in future years.

A summary of the status of the Company's  Plan at December 31, 2001 and 2000 and
changes  during  the years then ended is  presented  in the table and  narrative
below:


                                                                        

                                                             2001 2000
                                     Shares        Wtd. Avg. ex        Shares       Wtd. Avg. ex
                                                     price (1)                          price
                                 ---------------- ---------------- ---------------- --------------
Outstanding beginning
   of year                                 7,750     Cdn.$5.85             291,000    Cdn.$1.24
Granted                                   45,000     Cdn.$4.50              30,000    Cdn.$5.70
Exercised                                    Nil                         (299,500)    Cdn.$1.37
Canceled                                 (7,750)     Cdn.$5.85            (13,750)    Cdn.$5.70
                                 ----------------                  ----------------
Outstanding at end of
    Year                                  45,000     Cdn.$4.50               7,750    Cdn.$5.85
                                 ================                  ================
                                 ================                  ================

Exercisable at end of year                45,000                             7,750
                                 ================                  ================
                                 ================                  ================



(1) The US$ equivalent of Canadian $1.00 at December 31, 2001 was  approximately
$0.6287.

There are 857,324  options  available  for grant under the plan at December  31,
2001.  The average  remaining  contractual  life of the options  outstanding  at
December 31, 2001 is 3 years.




                              GLYKO BIOMEDICAL LTD.
                          NOTES TO FINANCIAL STATEMENTS


7.     Related Party Transactions

For the year  ended  December  31,  2001 and 2000,  we paid legal fees to Blake,
Cassels  and  Graydon  LLP in which two of our  directors,  Mr.  Kolada  and Mr.
Trossman are  partners.  During the years ended  December 31, 2001 and 2000,  we
incurred  expenses of $248,483  and  $142,208,  respectively,  payable to Blake,
Cassels and Graydon LLP, relating to general corporate services and, with
respect to legal fees paid for the year ended December 31, 2001, expenses
incurred also related to the transaction with BioMarin that has been discussed
herein.

Since October 8, 1998, we have agreed to pay BioMarin a monthly  management  and
reporting  fee  for  its  services  to  us  primarily  relating  to  management,
accounting,  finance and government reporting.  BioMarin had accrued receivables
relating to these  services  of zero and $9,000 at  December  31, 2001 and 2000,
respectively.

Mr. Sager is entitled to receive Cdn.$1,500.00 per month in connection with fees
and expenses  incurred as the Company's  President and Chief Executive  Officer,
which  entitlement  commenced  in June  2000.  Mr.  Sager  received  a lump  sum
pre-payment  of  approximately  Cdn.$42,300  in late  2000  for  these  fees and
expenses. As a result, as of February 2002, Mr. Sager has an outstanding prepaid
balance of Cdn.$10,800.

8.        Subsequent Events (unaudited)


In  December  2001,   BioMarin  signed  a  definitive   agreement  with  Synapse
Technologies  Inc. (a  privately  held  Canadian  company) to acquire all of its
outstanding  capital stock for  approximately  $10.2 million in BioMarin  common
stock plus future contingent  milestone  payments totaling $6 million payable in
cash or common stock at BioMarin's discretion. BioMarin will issue approximately
885,000  shares  of common  stock  for the  purchase.  The  acquisition  will be
recorded upon closing in the first quarter of 2002 using the purchase  method of
accounting.  All of the  purchase  price  along with  related  expenses  will be
expensed as in-process research and development costs.

On February 7, 2002, we signed a definitive  agreement with BioMarin to sell all
of our  outstanding  capital  stock in exchange for  approximately  11.4 million
shares of freely tradable  BioMarin's common stock.  There will be no net effect
to BioMarin's outstanding common stock, as BioMarin plans to retire the existing
shares of its restricted common stock currently held by us upon closing.  If the
proposed  purchase by BioMarin is approved by  stockholders  of BioMarin and our
shareholders and relevant regulatory authorities,  we will become a wholly-owned
indirect  subsidiary  of BioMarin and will  concurrently  repatriate  to British
Columbia as a private company with no operations.

9.     Quarterly Financial Data (unaudited)

The Company's  quarterly  operating  results have fluctuated in the past and may
continue  to do so in the future as a result of a number of  factors  including,
but not limited to, our share of BioMarin's  net losses,  which could  fluctuate
due to the  completion  of  development  projects  and  variations  in levels of
production and our ownership  share of BioMarin due to BioMarin's sale of common
stock in the future.

The Company's common shares have been traded on the Toronto Stock Exchange since
1992.  There were 112 common  shareholders  of record at December 31,  2001.  No
dividends were paid for the years ended December 31, 2001 and, 2000.



                                                                             

                                                                  Quarter Ended
                                        ------------------------------------------------------------------
                                       March 31,        June 30,      September 30,    December 31,
2001                                   ---------        --------      -------------    ------------
Total revenue                          $      -         $      -         $       -         $     -
Loss from operations                    (70,335)         (89,074)         (158,208)       (144,405)
Net loss                             (2,865,226)      (3,154,647)       (2,995,952)     (6,079,026)
Net loss per share, basic and diluted  $  (0.08)          $(0.09)           $(0.09)         $(0.18)

Common share price per share:
  High                                 $   5.70          $  6.45           $  7.00         $  7.00
  Low                                  $   3.80          $  3.85           $  3.75         $  3.75


                                                                  Quarter Ended
                                        ------------------------------------------------------------------
2000                                       March 31,        June 30,      September 30,    December 31,
                                           ---------        --------      -------------    ------------
Total revenue                            $         -        $     -         $     -        $       -
Loss from operations                         (52,605)       (80,226)       (150,500)        (105,002)
Net loss                                  (3,736,387)    (2,246,263)     (2,498,602)      (3,154,089)
Net loss per share, basic and diluted    $     (0.11)      $  (0.07)        $ (0.07)       $   (0.09)

Common share price per share:
  High                                   $     13.55       $   9.75         $  9.00        $    7.90
  Low                                    $      5.30       $   6.80         $  7.00        $    3.75