POWER OF ATTORNEY

Know all by these presents, that the undersigned hereby constitutes and
appoints Michele M. Miller of OraSure Technologies Inc. (the "Company"),
with full power to act as the undersigneds true and lawful attorney-in-
fact, with full power of substitution, to:

1. execute for and on behalf of the undersigned, in the undersigneds
capacity as an officer and/or director and/or beneficial owner of the
Company, the Update Passphrase, Consent of Reporting Person and Forms 3,
4 and 5 in accordance with Section 16(a) of the Securities Exchange Act
of 1934, as amended, and the rules thereunder;

2. do and perform any and all acts for and on behalf of the undersigned
which may be necessary or desirable to complete and execute any such Update
Passphrase, Consent of Reporting Person and Forms 3, 4 and 5, complete and
execute any amendment or amendments thereto, and timely file such form with
the United States Securities and Exchange Commission and any stock exchange
or similar authority; and

3. take any other action of any type whatsoever in connection with the
foregoing which, in the opinion of such attorney-in-fact, may be of benefit
to, in the best interest of, or legally required by, the undersigned, it
being understood that the documents executed by such attorney-in-fact on
behalf of the undersigned pursuant to this Power of Attorney shall be in such
form and shall contain such terms and conditions as such attorney-in-fact may
approve in such attorney-in-facts discretion.

The undersigned hereby grants to the attorney-in-fact full power and
authority to do and perform any and every act and thing whatsoever requisite,
necessary or proper to be done in the exercise of any of the rights and powers
herein granted, as fully to all intents and purposes as the undersigned might
or could do if personally present with full power of substitution or
revocation, hereby ratifying and confirming all that such attorney-in-fact or
such attorney-in-facts substitute or substitutes, shall lawfully do or cause
to be done by virtue of this power of attorney and the rights and powers
herein granted.

This power of attorney shall remain in full force and effect until revoked by
the undersigned in a signed writing delivered to the attorney-in-fact.

IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney
to be executed as of this 8th day of April, 2022.

					/s/ David J. Shulkin
					Name: David J. Shulkin
					Title: Director