POWER OF ATTORNEY

KNOW ALL BY THESE PRESENTS, that the undersigned hereby authorizes Jeffrey
S. Hackman, Michael G. Campbell, Jeffrey L. Quillen, Ryan M. Rourke Reed and
Stacie S. Aarestad,each acting singly, to execute and caused to be filed
with the United States Securities and Exchange Commission any and all documents
or filings, including any amendments thereto, required to be so filed.
The undersigned hereby grants to the attorney-in-fact full power and
authority to do and perform any and every act and thing whatsoever
requisite, necessary or proper to be done in the exercise of any of the
rights and powers herein granted, as fully to all intents and purposes as
the undersigned might or could do personally present, with full power of
substitution, resubstitution or revocation, hereby ratifying and confirming
all that such attorney-in-fact, or such attorney's-in-fact substitute or
substitutes, shall lawfully do or cause to be done by virtue of this power
of attorney and the rights and powers herein granted. The undersigned
acknowledges that the foregoing attorney-in-fact, in serving in such capacity
at the request of the undersigned, is not assuming any of the undersigned's
responsibilities to comply with all applicable laws, including Sections 13
 and 16 of the Securities Exchange Act of 1934.

This Power of Attorney shall remain in full force and effect until revoked
by the undersigned in a signed writing delivered to the foregoing attorney-in-
fact.

IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to
be executed as of this 3rd day of November, 2023.

/s/ Dorothy J. Clarke
Name: Dorothy J. Clarke