UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM 8-K

                CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF
                       THE SECURITIES EXCHANGE ACT OF 1934

       Date of report (date of earliest event reported): February 4, 2009

                          MISSION WEST PROPERTIES, INC.
             (Exact name of registrant as specified in its charter)

           Maryland               Commission File Number:          95-2635431
           --------                      1-8383                    ----------
(State or other jurisdiction of                                 (I.R.S. Employer
        incorporation)                                           Identification)



                    10050 Bandley Drive, Cupertino, CA 95014
                    (Address of principal executive offices)

                                 (408) 725-0700
              (Registrant's telephone number, including area code)

      Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
           following provisions (see General Instruction A.2. below):


[ ] Written communications pursuant to Rule 425 under the Securities Act
    (17 CFR 230.425)

[ ] Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
    240.14a-12)

[ ] Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange
    Act (17 CFR 240.14d-2(b))

[ ] Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange
    Act (17 CFR 240.13e-4(c))





ITEM 2.02. RESULTS OF OPERATIONS AND FINANCIAL CONDITION.

(a)  The following information is being furnished by the Company as required for
     Item  2.02(a)  of this  report  and shall not be deemed to be  "filed"  for
     purposes of Section 18 of the Securities Exchange Act of 1934:

On February 4, 2009, the Company issued a press release  announcing its earnings
results for the fourth  quarter and full year ended December 31, 2008. The press
release is attached to this Current  Report as Exhibit 99.1 and is  incorporated
by reference in response to Item 2.02(a) of this report.




- --------------------------------------------------------------------------------

                                    SIGNATURE

Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.




                                            MISSION WEST PROPERTIES, INC.

Date: February 5, 2009                      By: /s/ Wayne N. Pham
                                               ---------------------------------
                                               Wayne N. Pham
                                               Vice President of Finance and
                                               Controller




Exhibit 99.1


                                                                   PRESS RELEASE

For Immediate News Release
February 4, 2009


              MISSION WEST PROPERTIES ANNOUNCES FOURTH QUARTER AND
                        FULL YEAR 2008 OPERATING RESULTS

  "We build the buildings for the high tech companies that build the internet"

Cupertino, CA - Mission West Properties,  Inc. (NASDAQ: MSW) reported today that
Funds From  Operations  ("FFO")  for the  quarter  ended  December  31, 2008 was
approximately  $12,863,000,  or $0.12 per diluted common share, (considering the
potential  effect of all O.P. units being  exchanged for shares of the Company's
common  stock) as compared to  approximately  $13,992,000,  or $0.13 per diluted
common share,  for the same period in 2007. Net  termination fee income relating
to lease  terminations  for the fourth quarter ended December 31, 2008 accounted
for  approximately  $833,000,  or less than $0.01 per diluted common share. On a
sequential  quarter  basis,  FFO for the quarter  ended  September  30, 2008 was
approximately  $0.13 per  diluted  common  share.  For the twelve  months  ended
December 31, 2008,  FFO decreased to  $55,334,000,  or $0.52 per diluted  common
share, from FFO of $114,867,000, or $1.09 per diluted common share, for the same
period in 2007. Net termination  fees and security  deposit  forfeitures  income
relating to lease terminations accounted for approximately  $2,754,000, or $0.03
per diluted common share,  and  $51,721,000,  or $0.49 per diluted common share,
for the twelve months ended December 31, 2008 and 2007, respectively.

Net income per diluted  share to common  stockholders  was $0.26 for the quarter
ended  December 31, 2008  compared to $0.08 for the quarter  ended  December 31,
2007, a per share increase of approximately 225%. Gains from the sale of two R&D
properties in the Company's unconsolidated joint venture, TBI-MWP, accounted for
approximately  $0.20 per diluted common share for the quarter ended December 31,
2008.  The gains are  recorded  under the line  item,  "Equity  in  earnings  of
unconsolidated  joint  venture,"  using the  equity  method of  accounting.  Net
termination   fee  income   relating  to  lease   terminations   accounted   for
approximately  less than $0.01 per  diluted  common  share for the three  months
ended  December 31, 2008.  For the twelve  months ended  December 31, 2008,  net
income per diluted  share to common  stockholders  was $0.50,  down from $0.95 a
year ago, a per share decrease of approximately  47%. Gains from the sale of two
R&D properties in the Company's unconsolidated joint venture, TBI-MWP, accounted
for approximately $0.20 per diluted common share for the year ended December 31,
2008. Net termination fees and security deposit  forfeitures  income relating to
lease  terminations  accounted  for  approximately  $0.03 and $0.52 per  diluted
common  share  for  the  twelve  months  ended   December  31,  2008  and  2007,
respectively.

Company Profile

Mission West Properties, Inc. operates as a self-managed,  self-administered and
fully integrated REIT engaged in the management, leasing, marketing, development
and acquisition of commercial R&D properties,  primarily  located in the Silicon
Valley portion of the San Francisco Bay Area. Currently, the Company manages 111
properties  totaling  approximately  8.0 million  rentable  square  feet,  which
includes  approximately  854,000 rentable square feet (or 16 buildings) that are
in the process of being  rezoned for  residential  development.  For  additional
information, please contact Investor Relations at 408-725-0700.

The matters described herein contain forward-looking statements. Such statements
can be  identified  by the use of  forward-looking  terminology  such as "will,"
"anticipate," "estimate," "expect," "intends," or similar words. Forward-looking
statements involve a number of risks,  uncertainties or other factors beyond the
Company's  control,  which may cause  material  differences  in actual  results,
performance or other  expectations.  These factors include,  but are not limited
to, the ability to complete  acquisitions  under the Berg Land  Holdings  Option
Agreement  with the Berg  Group  and other  factors  detailed  in the  Company's
registration  statements,  and periodic  filings with the  Securities & Exchange
Commission.





                          MISSION WEST PROPERTIES, INC.
                             SELECTED FINANCIAL DATA
        (In thousands, except share, per share and property data amounts)





                                                   Three Months        Three Months       Twelve Months      Twelve Months
                                                       Ended               Ended              Ended              Ended
                                                   Dec 31, 2008        Dec 31, 2007       Dec 31, 2008       Dec 31, 2007
                                                  ----------------    ----------------   ----------------   ----------------
OPERATING REVENUES:
                                                                                                 
  Rental revenue from real estate                     $20,464             $18,986            $79,075            $80,337
  Above market lease intangible asset                       -                   -                  -             (4,091) (1)
amortization
  Tenant reimbursements                                 4,505               3,447             16,406             13,355
  Lease termination and settlement income               1,087                   -              3,007             57,515
  Other income                                            446                 659              1,216              4,467
                                                  ----------------    ----------------   ----------------   ----------------
    Total operating revenues                           26,502              23,092             99,704            151,583
                                                  ----------------    ----------------   ----------------   ----------------

OPERATING EXPENSES:
  Operating and maintenance                             3,410               2,632             11,404              9,791
  Real estate taxes                                     3,812               2,433             12,056             10,580
  General and administrative                              684                 666              2,635              3,035
  Depreciation and amortization of real estate          6,160 (2)           5,503 (2)         23,224 (2)         22,588 (2)
                                                  ----------------    ----------------   ----------------   ----------------
    Total operating expenses                           14,066              11,234             49,319             45,994
                                                  ----------------    ----------------   ----------------   ----------------

    Operating income                                   12,436              11,858             50,385            105,589

OTHER INCOME (EXPENSES):
  Equity in earnings of unconsolidated joint           18,701                 350             19,617              1,408
venture
  Interest income                                         164                 985              1,128              3,086
  Dividend income                                         607                   -                607                  -
  Unrealized loss from investment                        (278)                  -               (278)                 -
  Interest expense                                     (4,880)             (4,956)           (19,787)           (20,131)
  Interest expense - related parties                     (307)               (178)            (1,332)              (724)
                                                  ----------------    ----------------   ----------------   ----------------
    Income from continuing operations before
       minority interests                              26,443               8,059             50,340             89,228
  Minority interests from continuing operations       (21,186)             (6,491)           (40,206)           (71,471)
                                                  ----------------    ----------------   ----------------   ----------------
     Income from continuing operations                  5,257               1,568             10,134             17,757

Discontinued operations, net of minority interests:
  Gain from disposal of discontinued operations             -                   -                  -              1,126
  Income attributable to discontinued operations            -                   -                  -                  5
                                                  ----------------    ----------------   ----------------   ----------------
     Income from discontinued operations                    -                   -                  -              1,131
                                                  ----------------    ----------------   ----------------   ----------------

Net income to common stockholders                     $ 5,257              $1,568            $10,134            $18,888
                                                  ================    ================   ================   ================
Net income to minority interests                      $21,186              $6,491            $40,206            $76,960
                                                  ================    ================   ================   ================
Income per share from continuing operations:
   Basic                                               $0.27               $0.08             $0.51               $0.90
                                                  ================    ================   ================   ================
   Diluted                                             $0.26               $0.08             $0.50               $0.89
                                                  ================    ================   ================   ================
   Basic                                                 -                   -                 -                 $0.06
                                                  ================    ================   ================   ================
   Diluted                                               -                   -                 -                 $0.06
                                                  ================    ================   ================   ================
Net income per share to common stockholders:
   Basic                                               $0.27               $0.08              $0.51              $0.96
                                                  ================    ================   ================   ================
   Diluted                                             $0.26               $0.08              $0.50              $0.95
                                                  ================    ================   ================   ================
Weighted average shares of common stock (basic)     19,748,211          19,645,304         19,714,414         19,627,234
                                                  ================    ================   ================   ================
Weighted average shares of common stock (diluted)   20,018,836          19,710,909         20,226,385         19,854,411
                                                  ================    ================   ================   ================
Weighted average O.P. units outstanding             85,526,965          85,552,718         85,528,329         85,162,240
                                                  ================    ================   ================   ================










FUNDS FROM OPERATIONS
                                                                                               
Funds from operations                                  $12,863             $13,992            $55,334          $114,867
                                                  ================    ================   ================   ================
Funds from operations per share (3)                    $0.12               $0.13             $0.52               $1.09
                                                  ================    ================   ================   ================
Outstanding common stock                            19,748,211          19,664,087         19,748,211         19,664,087
                                                  ================    ================   ================   ================
Outstanding O.P. units                              85,526,965          85,533,935         85,526,965         85,533,935
                                                  ================    ================   ================   ================
Weighted average O.P. units and common stock
   outstanding (diluted)                            105,545,801         105,263,627        105,754,713        105,016,651
                                                  ================    ================   ================   ================


                                                   Three Months        Three Months       Twelve Months      Twelve Months
                                                       Ended               Ended              Ended              Ended
FUNDS FROM OPERATIONS CALCULATION                  Dec 31, 2008        Dec 31, 2007       Dec 31, 2008       Dec 31, 2007
                                                  ----------------    ----------------   ----------------   ----------------
Net income                                            $  5,257              $1,568            $10,134          $  18,888
Add:
   Minority interests (4)                               21,125               6,360             39,838             76,458
   Depreciation and amortization of real estate
      from continuing operations                         6,620               5,875             24,933             25,043
   Depreciation and amortization of real estate
      from discontinued operations                           -                   -                  -                250
   Depreciation and amortization of real estate
      held in unconsolidated joint venture                 332                 189                900                757
Less:
   Gain on sale of real estate                         (20,471)                  -            (20,471)            (6,529)
                                                  ----------------    ----------------   ----------------   ----------------
Funds from operations                                  $12,863             $13,992            $55,334           $114,867
                                                  ================    ================   ================   ================


Funds From Operations ("FFO") is a non-GAAP  financial  measurement used by real
estate investment trusts ("REITs") to measure and compare operating performance.
As defined by NAREIT,  FFO represents net income (loss) before minority interest
of unit  holders  (computed  in  accordance  with  GAAP,  accounting  principles
generally accepted in the United States of America), excluding gains (or losses)
from  debt  restructuring  and  sales of  property,  plus  real  estate  related
depreciation  and  amortization  (excluding  amortization of deferred  financing
costs and  depreciation  of non-real  estate assets) and after  adjustments  for
unconsolidated  partnerships and joint ventures.  Management considers FFO to be
an  appropriate  supplemental  measure of the Company's  operating and financial
performance  because  when  compared  year over year,  it reflects the impact to
operations  from trends in  occupancy  rates,  rental  rates,  operating  costs,
general and administrative  expenses and interest costs, providing a perspective
not immediately apparent from net income. In addition,  management believes that
FFO provides useful information about the Company's  financial  performance when
compared  to other  REITs  since FFO is  generally  recognized  as the  industry
standard for reporting the operations of REITs. FFO should neither be considered
as an  alternative  for net  income  as a  measure  of  profitability  nor is it
comparable  to  cash  flows  provided  by  operating  activities  determined  in
accordance with GAAP. FFO is not comparable to similarly entitled items reported
by other REITs that do not define them exactly as we define FFO.



                                                    Three Months       Three Months       Twelve Months      Twelve Months
                                                       Ended               Ended              Ended              Ended
PROPERTY AND OTHER DATA:                            Dec 31, 2008       Dec 31, 2007        Dec 31, 2008      Dec 31, 2007
                                                  ----------------   ----------------    ----------------  ----------------
                                                                                                  
Total properties, end of period                         111                 109                111                109
Total square feet, end of period                     8,047,569           7,861,692          8,047,569          7,861,692
Average monthly rental revenue per square foot (5)     $1.26               $1.28              $1.25              $1.42
Occupancy for leased properties                        66.4%               61.7%              66.4%              61.7%
Straight-line rent                                     $563                $310             $3,008            ($3,656)
Leasing commissions                                    $458                $352             $1,699             $3,000
Capital expenditures                                   $305                $257             $6,468             $4,878



LEASE ROLLOVER SCHEDULE:

Year                # of Leases       Rentable Square Feet
- ----------------    -------------     ---------------------
2009                      22                 369,613
2010                      12                 572,000
2011                      15                 827,605
2012                      13               1,001,452
2013                       6                 459,737
2014                      11               1,281,952
2015                       4                 328,211
2016                       2                 144,600
2017                       3                 241,089
Thereafter                 1                 119,756
                    -------------     ---------------------
    Total                 89               5,346,015
                    =============     =====================







                                 BALANCE SHEETS



                                               December 31, 2008     December 31, 2007
                                              --------------------  --------------------

                                     Assets

Investments in real estate:
                                                                 
  Land                                            $  320,911            $  312,152
  Buildings and improvements                         799,471               764,665
  Real estate related intangible assets                3,240                 2,119
                                              --------------------  --------------------
     Total investments in properties               1,123,622             1,078,936
  Accumulated depreciation and amortization         (180,043)             (156,819)
                                              --------------------  --------------------
      Net investments in properties                  943,579               922,117
  Investment in unconsolidated joint venture           3,768                 2,735
                                              --------------------  --------------------
      Net investments in real estate                 947,347               924,852
  Cash and cash equivalents                                -                23,691
  Restricted cash                                     39,478                65,509
  Investment in marketable securities                  3,368                     -
  Deferred rent                                       17,841                14,833
  Other assets, net                                   26,251                25,000
                                              --------------------  --------------------
      Total assets                                $1,034,285            $1,053,885
                                              ====================  ====================

                      Liabilities and Stockholders' Equity

Liabilities:
  Mortgage notes payable                         $   330,908           $   337,520
  Mortgage note payable - related parties              8,761                 9,224
  Revolving line of credit                            13,079                     -
  Interest payable                                     1,596                 1,331
  Security deposits                                    5,272                 4,754
  Deferred rental income                               3,964                 3,302
  Dividends and distributions payable                 21,055                16,832
  Accounts payable and accrued expenses               17,747                15,618
                                              --------------------  --------------------
      Total liabilities                              402,382               388,581
                                              --------------------  --------------------

Commitments and contingencies.

Minority interests in operating partnerships         497,485               526,626
                                              --------------------  --------------------

Stockholders' equity:
  Common stock, $.001 par value                           20                    20
  Additional paid-in capital                         154,412               153,024
  Distributions in excess of accumulated             (20,014)              (14,366)
earnings
                                              --------------------  --------------------
      Total stockholders' equity                     134,418               138,678
                                              --------------------  --------------------
      Total liabilities and stockholders' equity  $1,034,285            $1,053,885
                                              ====================  ====================



(1)  Amortization  of  an  above-market   lease  intangible  asset  pursuant  to
     Statement   of   Financial   Accounting   Standard   No.   141,   "Business
     Combinations."

(2)  Includes  approximately $159 and $267 in amortization expense for the three
     months ended December 31, 2008 and 2007, respectively,  and $600 and $2,153
     in  amortization  expense for the twelve months ended December 31, 2008 and
     2007, respectively, for the amortization of in-place lease value intangible
     asset  pursuant to  Statement  of  Financial  Accounting  Standard No. 141,
     "Business Combinations."

(3)  Calculated  on a fully diluted  basis.  Assumes  conversion  of O.P.  units
     outstanding into the Company's common stock.

(4)  The  minority  interest  for third  parties  has been  deducted  from total
     minority interest in calculating FFO.

(5)  Average  monthly  rental  revenue  per square foot has been  determined  by
     taking the cash base rent for the period divided by the number of months in
     the period,  and then  divided by the average  occupied  square feet in the
     period.