UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM 8-K
                                 CURRENT REPORT

Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): January 28, 2005

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                         NATIONAL SCIENTIFIC CORPORATION
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             (Exact name of registrant as specified in its charter)


          Texas                      000-28745                 86-0837077
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(State or Other Jurisdiction       (Commission                (IRS Employer
     of Incorporation)             File Number)           Identification Number)


14505 N. Hayden Road, Suite 305, Scottsdale, Arizona              85260
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(Address of principal executive offices)                       (Zip Code)


Registrants telephone number, including area code:  (480) 948-8324


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         (Former name or former address, if changed since last report)

Check  the  appropriate  box  below  if the  Form  8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2 below):

[ ]  Written communications pursuant to Rule 425 under the Securities Act (17CFR
     230.425)
[ ]  Soliciting  material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
     240.14a-12)
[ ]  Pre-commencement   communications  pursuant  to  Rule  14d-2(b)  under  the
     Exchange Act (17 CFR 240.14d-2(b))
[ ]  Pre-commencement   communications  pursuant  to  Rule  13e-4(C)  under  the
     Exchange Act (17 CFR 240.13e-4c))




ITEM 1.01.   Entry into a Material Definitive Agreement.

On January 28, 2005,  National  Scientific  Corporation  ("NSC")  entered into a
Securities  Exchange  Agreement  (the  "Agreement")  with  TurboWorks,  Inc.,  a
Delaware corporation  ("Turbo") that provides for the exchange of 360,000 shares
of the common  stock of Turbo plus  $240,000 in cash in exchange  for  7,150,000
shares of NSC  common  stock (the  "Exchange").  NSC and Turbo  consummated  the
Exchange on February 1, 2005.

NSC has agreed to  distribute  at least  180,000 of the shares of Turbo stock it
received in the  Exchange to NSC  shareholders  of record on a pro rata basis as
soon as practicable after the effective date of a registration statement on Form
SB-2 registering the Turbo shares to be distributed to NSC  shareholders.  Turbo
has agreed to file such registration  statement within the next 30 days, and has
agreed  to use its  best  efforts  to have  such  filed  registration  statement
declared effective no later than 90 days following the filing date.

The parties have also granted each other certain "piggyback" registration rights
regarding the exchanged  shares.  The registration  rights terminate on December
31, 2007.

The foregoing  summary is qualified in its entirety by the  Securities  Exchange
Agreement incorporated herein as Exhibit 10.1.

The  Exchange  is  a  further  development  resulting  from  the  Memorandum  of
Understanding  entered into between NSC and Turbo on October 29, 2004  regarding
the joint development of technology and joint marketing.

ITEM 9.01. Financial Statements and Exhibits.

(c)      Exhibits

10.1.    Securities Exchange Agreement
99.1     Press Release issued by the Registrant dated February 2, 2004.


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                                   SIGNATURES

     Pursuant to the  requirements  of the Securities  Exchange Act of 1934, the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.

                                                NATIONAL SCIENTIFIC CORPORATION

                                                By: /s/ Michael A Grollman
                                                    ----------------------------
                                                    Its: Chief Executive Officer

                                                Dated: February 1, 2005


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                                  EXHIBIT INDEX

EXHIBIT
NUMBER          DESCRIPTION

 10.1     Securities Exchange Agreement dated January 28, 2005

 99.1     Press Release issued by the Registrant dated February 2, 2004.



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