EXHIBIT 16.1 September 15, 2003 Securities and Exchange Commission 450 Fifth Street, N.W. Washington, D.C. 20549 Re: Advanced Nutraceuticals, Inc. Commission File No. 000-26362 Dear Sir or Madam: We have read Item 4 of the Form 8-K of Advanced Nutraceuticals Inc. dated September 10, 2003 and agree with the Statements concerning our Firm contained therein. Very truly yours, Grant Thornton LLP -4-