Exhibit Item 1016 (b) (v)



                               FOURTH AMENDMENT TO
                     REVOLVING CREDIT, TERM LOAN, EQUIPMENT
                  ACQUISITION TERM LOAN AND SECURITY AGREEMENT

     THIS FOURTH AMENDMENT TO REVOLVING CREDIT, TERM LOAN, EQUIPMENT ACQUISITION
TERM LOAN AND SECURITY  AGREEMENT (the  "Amendment")  is entered into as of July
__, 2005 to be effective as of the Fourth  Amendment  Effective Date (as defined
herein) by and between  CAPITALSOURCE  FINANCE LLC, a Delaware limited liability
company   ("Agent"),   the   Lenders   party   thereto   and  each  of  ADVANCED
NUTRACEUTICALS,  INC., a Texas corporation  ("Parent"),  BACTOLAC PHARMACEUTICAL
INC.,  a  Delaware   corporation   ("Bactolac"),   and  NIB,  INC.   (f/k/a  ANI
PHARMACEUTICALS,  INC.),  a  Mississippi  corporation  ("NIB") and together with
Parent and  Bactolac,  each a "Borrower"  and  collectively,  the  "Borrowers").
Capitalized  terms used and not defined herein shall have the meanings  assigned
to such terms in the Agreement.

     A.  WHEREAS,  Agent,  Lenders and  Borrowers  are  parties to that  certain
Revolving  Credit,  Term  Loan,  Equipment  Acquisition  Term Loan and  Security
Agreement dated as of March 21, 2003 as amended by a First Amendment dated as of
December 31, 2003, a Second Amendment dated March 23, 2004 and a Third Amendment
dated  January  6, 2005 (as  heretofore  and  hereafter  amended,  supplemented,
modified  and/or  restated  from time to time,  collectively  the  "Agreement"),
pursuant to which the Lenders made Advances and Loans to the Borrowers;

     B. WHEREAS, Borrowers have requested that Agent and Lenders agree to permit
Parent to purchase  shares of its capital  stock at a maximum price of $4.50 per
share and $4,500,000 in the aggregate for all shares so purchased  pursuant to a
Tender Offer (as hereinafter defined);

     C. WHEREAS,  in connection  with the Tender Offer Borrowers have requested,
among other things that:  (i) the Term Lenders agree to fund the Term Loan up to
$4,000,000; and (ii) the Lenders agree to extend the Maturity Date of the Loans,
in each case,  to provide  financing  for  ongoing  working  capital  and to pay
expenses  related to the Tender  Offer,  and the Term  Lenders and  Lenders,  as
applicable,  have agreed to do so,  subject to the terms and  conditions of this
Amendment; and

     D.  WHEREAS,  Borrowers  have  agreed  with  Agent  and  Lenders  that,  in
connection  with the Tender  Offer and the  transactions  contemplated  thereby,
other specified terms of the Agreement shall be amended as provided herein.

     NOW, THEREFORE, in consideration of the terms and conditions,  premises and
the  other  mutual  covenants  contained  herein,  and other  good and  valuable
consideration,  the receipt and sufficiency are hereby acknowledged, the parties
hereto agree as follows:

     SECTION 1. Amendments. The sections,  definitions,  schedules,  annexes and
exhibits,  as applicable,  of and to the Agreement  referenced  and/or set forth
below are hereby amended as of the Fourth Amendment Effective Date as follows:







     (a) Amendments to Revolving Loans.
         ------------------------------

          (i)  Section  2.3 of the  Agreement  is  amended:  (a) to delete  "two
     percent  (2.00%)" and to  substitute  "one half of one percent  (0.50%)" in
     place thereof;  and (b) to delete "six and one half of one percent (6.50%)"
     and to  substitute  "six and one quarter of one  percent  (6.25%)" in place
     thereof.

          (ii)  Section  2.5 of the  Agreement  is  amended to delete the phrase
     "five (5)  Business  Day  clearance  charge" and to  substitute  the phrase
     "three (3) Business Day clearance charge" in place thereof.

     (b) Amendments to Term Loan.
         ------------------------

          (i) The first  "WHEREAS"  clause in the  recitals to the  Agreement is
     deleted in the entirety and the following is substituted in place thereof:

     "WHEREAS, Borrowers have requested that Lenders make available to Borrowers
     (i) a revolving  credit  facility (the  "Revolving  Facility") in a maximum
     principal  amount  at any time  outstanding  of up to Two  Million  Dollars
     ($2,500,000)  (the "Facility  Cap"), and (ii) on the Tender Offer Borrowing
     Date,  a term loan (the  "Term  Loan") in an  aggregate  maximum  principal
     amount of up to Four Million  Dollars  ($4,000,000),  the proceeds of which
     Revolving  Facility  and Term Loan shall be used solely (i) by Borrowers to
     finance the working  capital  needs of Borrowers in  connection  with their
     nutraceutical  vitamin  liquid  and powder  based  products  business  (the
     "Business");  and (ii) by the Parent to fund the Tender Offer  Transaction,
     in each case (i) and (ii), subject to the terms and conditions contained in
     this Agreement;

          (ii)  Section  2.6 is deleted in the  entirety  and the  following  is
     substituted in place thereof:

     "2.6 Term Loan.  Subject to and upon the terms and  conditions set forth in
     this Agreement,  each Term Lender agrees to loan to the Borrowers  pursuant
     to a single  drawing on the Tender Offer  Borrowing Date its Pro Rata Share
     of the Term Loan,  which,  in the aggregate,  equals an original  principal
     amount of up to Four Million Dollars  ($4,000,000),  which shall be secured
     by all of the Collateral.  The Term Loan is not a revolving credit facility
     and may not be drawn,  repaid and redrawn.  Any  repayments of principal on
     the Term Loan shall be applied to  permanently  reduce such Term Loan.  The
     obligations  of the Term  Lenders  hereunder  are  several and not joint or
     joint  and  several.   On  the  Tender  Offer  Borrowing  Date,   Borrowers
     irrevocably  authorize  Agent and Term  Lenders to disburse the proceeds of
     the Term Loan,  in an amount  necessary  to fund  solely  the Tender  Offer
     Transaction,  to the  applicable  account(s)  of  Borrowers  set  forth  on
     Schedule  2.4,  in all cases  for  credit to  Borrowers  (or to such  other
     account as to which the  Borrowers  shall  instruct  Agent in writing)  via
     Federal funds wire transfer no later than 3:00 p.m. (New York City time)."

          (iii) Section 2.7(a) of the Agreement is amended:  (a) to delete "four
     and three quarters of one percent (4.75%)" and to substitute "three percent
     (3.0%)"  in place  thereof;  (b) to  delete  "nine and one  quarter  of one
     percent (9.25%)" and to substitute "eight and three quarters of one percent
     (8.75%)" in place  thereof;  and (c) to delete the date "April 1, 2003" and
     to substitute "September 1, 2005" in place thereof.

          (iv)  Section 2.8 of the  Agreement is deleted in the entirety and the
     following is substituted in place thereof:



     "2.8. Repayment of Term Loan; Maturity.

     (a) Payment of the  outstanding  principal  balance under the Term Loan (in
addition to the interest  payments in Section 2.7) and all other amounts  (other
than  interest)  outstanding  under the Term  Loan  shall be made on each of the
quarterly payment dates indicated below in the amounts set forth below:

                          Payment Dates                            Payment
                          -------------                            -------
        On each of September, 1, 2005, December 1, 2005,
        March 1, 2006 and June 1, 2006                            $250,000

        On each of September 1, 2006, December 1, 2006,
        March 1, 2007 and June 1, 2007                            $312,500

        On each of September 1, 2007, December 1, 2007,
        March 1, 2008 and June 1, 2008                            $437,500


     (b) The unpaid principal amount of the Term Loan and all other  Obligations
under the Term Loan shall be due and  payable in full,  and the Term Notes shall
mature, if not earlier in accordance with this Agreement, on the Maturity Date."

     (c) Amendments to Equipment Acquisition Term Loan. The Borrowers, Agent and
Lenders  agree  that on the  Fourth  Amendment  Effective  Date,  the  Equipment
Acquisition Term Loan that was previously  extended to Borrowers and which has a
balance of zero dollars ($0),  shall terminate and the Borrowers shall no longer
be entitled to request  Draws  thereunder  and the  Equipment  Acquisition  Term
Lenders shall no longer have any  obligation  to make any Equipment  Acquisition
Term Loans.  The Borrowers,  Agent and Lenders  further agree that the Equipment
Acquisition  Term Note  shall be deemed  cancelled  as of the  Fourth  Amendment
Effective  Date, and shall be returned to the Borrowers as soon as  practicable.
The  termination  of the  Equipment  Acquisition  Term Loan shall not affect the
Borrowers'  duties,  obligations and covenants under the Agreement,  which shall
remain in effect  until  the  Obligations  are  repaid  in  accordance  with the
Agreement. In furtherance of the foregoing:

          (i) The second  "WHEREAS"  clause in the recitals to the  Agreement is
     deleted in the entirety.

          (ii) The third  "WHEREAS"  clause in the recitals to the  Agreement is
     amended to delete the phrase  "Equipment  Acquisition  Term Loan" set forth
     therein.

          (iii)  Section 2.9 of the Agreement is deleted in the entirety and the
     following is substituted in place thereof: "2.9 Intentionally Omitted."

          (iv) Section 2.10 of the  Agreement is deleted in the entirety and the
     following is substituted in place thereof: "2.10 Intentionally Omitted."

          (v) Section  2.11 of the  Agreement is deleted in the entirety and the
     following is substituted in place thereof: "2.11 Intentionally Omitted."

          (vi) Section  2.14(b) of the Agreement is amended to delete the phrase
     "fourth, to the principal payments due under the Equipment Acquisition Term
     in the inverse order of their maturities; and fifth to the principal amount
     of the Revolving  Loans" set forth therein and to substitute  the following
     in place  thereof:  "and fourth to the  principal  amount of the  Revolving
     Loans".


          (vii) Section  2.17(d) of the Agreement is amended to delete the third
     sentence set forth therein.

          (viii)  Section 2.21 of the  Agreement is amended to delete the phrase
     "the  Equipment  Acquisition  Term  Loan"  set forth  therein  each time it
     appears therein.

          (ix) Section 4.1 of the  Agreement is amended to delete the phrase "to
     fund the  initial  Draw  under  the  Equipment  Acquisition  Term Loan (the
     "Initial Draw")" set forth therein.

          (x) Section  4.1(a) of the  Agreement  is amended to delete the phrase
     "and a Draw Notice for the  Initial  Draw under the  Equipment  Acquisition
     Term Loan" set forth therein.

          (xi) Section  4.1(d) of the  Agreement is amended to delete the phrase
     "and  the  date  of  funding  of  the  Initial  Draw  under  the  Equipment
     Acquisition Term Facility" set forth therein.

          (xii) Section  4.1(f) of the Agreement is amended to delete the phrase
     "and/or Initial Draw" set forth therein.

          (xiii)  Section 4.2 of the  Agreement  is amended to delete the phrase
     "and/or  to fund  any  Draw  under  the  Equipment  Acquisition  Term  Loan
     (including, without limitation, the Initial Draw)" set forth therein.

          (xiv) Section  4.2(a) of the  Agreement is amended to delete:  (a) the
     phrase  "and  (ii) in the  case of a Draw,  a Draw  Notice  with  necessary
     supporting  documentation" set forth therein;  and (b) the word "Draws" set
     forth therein.

          (xv) Section  4.2(b) of the  Agreement  is amended to delete:  (a) the
     phrase ", and/or funding of the Draw" set forth therein; and (b) the phrase
     "and/or Draw" set forth therein.

          (xvi) Section  4.2(c) of the Agreement is amended to delete the phrase
     ", Term Loan, or Draw," set forth  therein and to substitute  the following
     in place thereof: "or Term Loan,".

          (xvii) Article V of the Agreement is amended to delete the phrase "the
     date of the  funding  of the  Term  Loan  and the  date of any  Draw on the
     Equipment  Acquisition  Term Loan as  follows:"  set forth  therein  and to
     substitute the following in place thereof:  "and the date of funding of the
     Term Loan as follows:".

          (xviii)  Section 5.23 of the Agreement is amended to delete the phrase
     "and/or the funding of any Draw" set forth therein.

          (xix)  Section  6.2 of the  Agreement  is amended to delete the phrase
     "Equipment Acquisition Term Loan" set forth therein.

          (xx) Section 6.11 of the  Agreement is amended to delete the phrase ",
     the Term Loan and the Equipment Acquisition Term Loan" and the following is
     substituted in place thereof: "and the Term Loan".


          (xxi)  Section  7.8 of the  Agreement  is amended to delete the phrase
     "other than Eligible  Equipment the purchase of which was financed  through
     an Equipment Acquisition Term Loan" set forth therein.

          (xxii)  Section 9.1 of the  Agreement  is amended to delete the phrase
     "the  Maximum  Equipment   Acquisition  Term  Loan  Amount,  the  Equipment
     Percentage" set forth therein.

          (xxiii)  Section 10.5 of the Agreement is amended to delete the phrase
     "and Equipment Acquisition Term Lenders" set forth therein.

          (xxiv)  Section 12.3 of the  Agreement is amended to delete the second
     sentence  set  forth  therein  and to  substitute  the  following  in place
     thereof:

         "Any Term Lender which has exercised its right to set off or otherwise
         has received any payment on account of the Obligations shall, to the
         extent the amount of any such set off or payment exceeds its Pro Rata
         Share of payments obtained by all of the Term Lenders, on account of
         such Obligations, purchase for cash (and the other Term Lenders shall
         sell) participations in each such other Term Lender's Pro Rata Share of
         Obligations as would be necessary to cause such Term Lender to share
         such excess with each other Term Lenders, in accordance with their
         respective Pro Rata Shares; provided, however, that if all or any
         portion of such excess payment or benefits is thereafter recovered from
         such purchasing Term Lender, such purchase shall be rescinded, and the
         purchase price and benefits returned, to the extent of such recovery."

          (xxv) Exhibit B (Form of Draw Notice) is deleted in the entirety.

          (xxvi) All  references to the Equipment  Acquisition  Term Loan in the
     Loan Documents shall be deemed deleted in the entirety.

     (d) Amendments to Permit Tender Offer Transaction.

          (i)  Section  5.13 of the  Agreement  is  amended to delete the second
     sentence  set  forth  therein  and to  substitute  the  following  in place
     thereof:

                  "Each Borrower is and, after giving effect to the transactions
                  and the Indebtedness contemplated by the Loan Documents
                  (including, without limitation, the Term Loan that will be
                  made on the Tender Offer Borrowing Date), shall be solvent and
                  able to meet its obligations and liabilities as they become
                  due, and the assets of such Borrower, at a Fair Valuation,
                  exceed the total liabilities (including contingent,
                  subordinated, unmatured and unliquidated liabilities) of such
                  Borrower, and no unreasonably small capital base with which to
                  engage in its anticipated business exists with respect to such
                  Borrower."


          (ii) Section 5.14 of the  Agreement is amended to add the following in
     between the first and second sentences set forth therein:

                  "Borrowers shall deliver to Agent true and correct copies of
                  all Tender Offer Documents. No Tender Offer Document furnished
                  to Agent by or on behalf of any Borrower, nor any
                  representation or warranty made by any Borrower in any Tender
                  Offer Document, in any Loan Document or otherwise in
                  connection with any Tender Offer Document, contains any untrue
                  statement of material fact or omits to state any fact
                  necessary to make the factual statements therein taken as a
                  whole not materially misleading in light of the circumstances
                  under which it was furnished."



          (iii) Section 7.5 of the Agreement is amended to delete subsection (b)
     thereof and to substitute the following in place thereof:

                  "(b) apply any of its funds, property or assets to the
                  acquisition, redemption or other retirement of any capital
                  stock or other securities or interests or of any options to
                  purchase or acquire any of the foregoing (provided, however,
                  that (x) such Borrower may redeem its capital stock from
                  terminated employees, non-employee directors and consultants
                  pursuant to, but only to the extent required under, the terms
                  of the related employment or other compensation-related
                  agreements as long as no Default or Event of Default has
                  occurred and is continuing or would be caused by or result
                  therefrom and (y) Parent may consummate the Tender Offer
                  Transaction in accordance with the terms and conditions set
                  forth in this Agreement, which Tender Offer Transaction must
                  be fully consummated on or before December 31, 2005 and must
                  be on terms and conditions and pursuant to documentation
                  satisfactory to Agent in its Permitted Discretion),"

          (iv)  Section 7.7 of the  Agreement is amended to delete the period at
     the end of the last  sentence  set  forth  therein  and to  substitute  the
     following in place thereof:

                  " or (k) amend, modify, restate or change any term or
                  provision of any Tender Offer Document in a manner that would
                  be adverse to Agent or any Lender."

          (v) Section  7.11 of the  Agreement is deleted in the entirety and the
     following is substituted in place thereof.

     "7.11. Tender Offer.

     (a)  On the Tender Offer  Borrowing  Date: (i) all conditions  precedent to
          the  consummation of the Tender Offer as set forth in the Tender Offer
          Documents  shall  have  been  satisfied;  and  (ii) all  consents  and
          approvals  of,  and  filings  and  registrations  with,  and all other
          actions  in respect  of, all  governmental  agencies,  authorities  or
          instrumentalities  (including,  without limitation, the Securities and
          Exchange  Commission and each applicable state  securities  authority)
          required in order to make or consummate the Tender Offer in accordance
          with the terms of the Tender Offer  Documents and all applicable  laws
          shall have been  complied  with and all required  consents  shall have
          been  obtained,  given,  filed or taken and shall be in full force and
          effect; and

     (b)  Within three (3) Business Days  following  the Tender Offer  Borrowing
          Date (or such longer period  following the Tender Offer Borrowing Date
          as shall be  acceptable  to the  Agent  in its sole  discretion),  the
          Parent shall have:  (i)  utilized  the proceeds  from the Term Loan to
          purchase  all of  Parent's  Common  Stock  that is  tendered,  and not
          theretofore  withdrawn,  pursuant to the Tender  Offer (or such lesser
          amount of shares as is  specified by the Tender  Offer  Documents)  in
          accordance  with  the  relevant   requirements  of  the  Tender  Offer
          Documents and all applicable laws; and (ii) immediately following such
          purchase,  retired  all of the  shares  of  Parent's  Common  Stock so
          purchased."



     (e)  General Amendments.

          (i) Excess Cash Flow Recapture.  A new Section 2.14(c) is added to the
     Agreement as follows:

     "(d) On the day of delivery to Agent of Borrowers' annual audited financial
     statements in accordance with the terms of this Agreement, but in any event
     no later than the one-hundred  fifteenth  (115th) day after the end of each
     fiscal year of Borrower (commencing with the fiscal year of Borrower ending
     September 30, 2006),  Borrower shall furnish to Agent a written calculation
     of  Excess  Cash  Flow for such  fiscal  year and  deliver  to  Agent,  for
     distribution  to Lenders,  an amount equal to fifty  percent  (50%) of such
     Excess Cash Flow, for application to the Loans and the other Obligations in
     accordance with the following: first, to all then unpaid fees and expenses;
     second,  to all accrued and unpaid  interest  on the Loans;  third,  to the
     principal  payments  due under the Term Loan in the inverse  order of their
     maturities;  and fourth,  to the principal  amount of the Revolving  Loans;
     provided however,  that the reduction of the principal balance of the Loans
     shall not affect the amount or timing of principal payments (other than the
     extent to which  reductions  have been made with respect to such  principal
     payments as  allocated  pursuant  to this  paragraph)  required  under this
     Agreement until the balance of such Loans is reduced to zero."

          (ii) Notes.  Section 2.19 of the  Agreement is deleted in the entirety
     and the following is substituted in place thereof:

     "2.19 Evidence of Loans.

     (a) Each Lender shall  maintain,  in  accordance  with its usual  practice,
     electronic or written records  evidencing the  indebtedness and obligations
     to such  Lender  resulting  from each Loan made by such Lender from time to
     time and the amounts of  principal  and  interest  payable and paid to such
     Lender from time to time under this Agreement.

     (b) Agent shall maintain  electronic or written records (the "Register") in
     which it will record (i) the amount of each Loan made hereunder,  the class
     and type of each Loan made and any applicable  interest rate periods,  (ii)
     the amount of any  principal  and/or  interest  due and  payable  and/or to
     become due and payable from  Borrowers to each Lender  hereunder  and (iii)
     all amounts  received by Agent  hereunder  from Borrowers and each Lender's
     share thereof.

     (c) The  entries  in the  Register  shall be prima  facie  evidence  of the
     existence and amounts of the obligations and indebtedness therein recorded;
     provided,  however,  that the failure of Agent to maintain  such records or
     any error  therein  shall  not in any  manner  affect  the  obligations  of
     Borrowers to repay the Loans or Obligations in accordance with their terms.

     (d)  Borrowers  agrees  that:  (a) all  references  to  "Notes" in the Loan
     Documents  shall mean all then existing Notes, if any, to the extent issued
     (and not returned to Borrowers in reliance upon Section  2.19(c)  above) as
     the same may be amended,  supplemented,  modified,  divided and/or restated
     and in  effect  from  time to  time;  (b) all  references  to any  returned
     "Revolving  Notes"  in the Loan  Documents  shall be deemed to refer to the
     Revolving Loans (without  duplication of such term); and (c) all references
     to any returned "Term Notes" in the Loan Documents shall be deemed to refer
     to the Term Loans (without duplication of such term); and


     (e) Borrowers agree that:

          (i) upon written  notice by Agent to Borrowers  that a new  promissory
          note or other  evidence of  indebtedness  is  requested  by Agent (for
          itself or on behalf of any  Lender)  to  evidence  the Loans and other
          Obligations  owing  or  payable  to,  or to be made by,  such  Lender,
          Borrowers  promptly  shall (and in any event within three (3) Business
          Days of any such request)  execute and deliver to Agent an appropriate
          Note or Notes in form and substance  reasonably  satisfactory to Agent
          and  Borrowers,  payable  to the order of such  Lender in a  principal
          amount  equal to the  amount of the  Loans  owing or  payable  to such
          Lender; and

          (ii) upon  Agent's  written  request  (for  itself or on behalf of any
          Lender),  and in any event within three (3) Business  Days of any such
          request, Borrowers shall execute and deliver to Agent new Notes and/or
          split or divide the Notes,  or any of them,  in exchange  for the then
          existing  subject Notes, in such smaller amounts or  denominations  as
          Agent or such  Lender  shall  specify;  provided,  that the  aggregate
          principal  amount of such new, split or divided Notes shall not exceed
          the aggregate  principal  amount of the Notes  outstanding at the time
          such request is made; and provided,  further, that such Notes that are
          replaced  shall  then be deemed no longer  outstanding  hereunder  and
          replaced  by such  new  Notes  and  returned  to  Borrowers  within  a
          reasonable  period of time after  Agent's  receipt of the  replacement
          Notes."

          (iii)  Section  13.11 of the  Agreement is deleted in the entirety and
          the following is substituted in place thereof:

          "13.11  Release  of  Collateral.  Subject to  Section  12.3,  promptly
          following full performance and  satisfaction and indefeasible  payment
          in  full  in  cash of all  Obligations  and  the  termination  of this
          Agreement and the  execution and delivery of a written  release by the
          Borrowers of all claims  against Agent and Lenders,  and so long as no
          suits,  actions,  proceedings,  or claims are  pending  or  threatened
          against  any  Indemnified  Person  asserting  any  damages,  losses or
          liabilities that are indemnified liabilities hereunder, then the Liens
          created hereby shall terminate and Agent and Lenders shall execute and
          deliver such  documents,  at Borrowers'  expense,  as are necessary to
          release  Lenders'  Liens  in  the  Collateral  and  shall  return  the
          Collateral to  Borrowers;  provided,  however,  that the parties agree
          that,   notwithstanding   any  such  termination  or  release  or  the
          execution,  delivery or filing of any such  documents or the return of
          any  Collateral,  if and to the extent that any such  payment  made or
          received with respect to the Obligations is subsequently  invalidated,
          determined to be fraudulent or  preferential,  set aside,  defeased or
          required to be repaid to a trustee,  debtor in  possession,  receiver,
          custodian or any other Person under any Debtor Relief Law,  common law
          or equitable cause or any other law, then the Obligations  intended to
          be satisfied by such payment shall be revived and shall continue as if
          such  payment  had not been  received  by Agent or any  Lender and the
          Liens created hereby shall be revived automatically without any action
          on the part of any party hereto and shall  continue as if such payment
          had not been received by Agent or any Lender.  Agent and Lenders shall
          not be deemed to have made any representation or warranty with respect
          to any Collateral so delivered except that such Collateral is free and
          clear, on the date of such delivery, of any and all Liens arising from
          such Person's own acts."



     (f)  Amendments  to Fees.  Section 3.1 of the  Agreement is deleted and the
following is substituted in place thereof:

          "3.1.  Commitment  Fee.  On or before the Fourth  Amendment  Effective
     Date,  Borrowers  shall pay to Agent,  for the ratable benefit of Revolving
     Lenders, a nonrefundable commitment fee equal to Thirty Seven Thousand Five
     Hundred  Dollars  ($37,500).  On or before the Fourth  Amendment  Effective
     Date,  Borrowers  shall  pay to  Agent,  for the  ratable  benefit  of Term
     Lenders,  a nonrefundable  commitment fee equal to Eighty Thousand  Dollars
     ($80,000)."

     (g) Amendments to Commitments and Financial Covenants.

          (i)  Schedule  A of the  Agreement  is  deleted  in the  entirety  and
     Schedule A attached hereto is substituted in place thereof.

          (ii) Annex I of the  Agreement  is deleted in the entirety and Annex I
     attached hereto is substituted in place thereof.


     (h) Amendments to Definitions. Appendix A is amended as follows:

     (i) The following  definitions  are added in the  appropriate  alphabetical
order:

     (a)  "Amended and  Restated  Disclosure  Schedules"  shall have the meaning
          given such term in Section 3 of the Fourth Amendment.

     (b)  "Excess Cash Flow" shall mean, at any date of  determination,  without
          duplication, an amount equal to the sum of (i) consolidated net income
          or loss of Borrowers and their Subsidiaries for such period, plus (ii)
          an amount equal to the amount of depreciation  expenses,  amortization
          expense  (including the  amortization or impairment of goodwill to the
          extent  deducted in  determining  consolidated  net  income),  accrued
          non-cash interest expense,  and all other non-cash charges deducted in
          arriving at such consolidated net income or loss, plus (iii) an amount
          equal to the aggregate net cash proceeds of the sale, lease,  transfer
          or other  disposition  of assets by the Borrowers  their  Subsidiaries
          during  such  period to the  extent  not  required  to be  applied  to
          mandatory prepayments or payments on the Loans and other than sales of
          Inventory in the ordinary course of business,  plus (iv) the amount of
          any cash tax  refunds  received  by  Borrower  and their  Subsidiaries
          during such period,  less (v) an amount equal to the aggregate  amount
          of all prepayments of the Term Loan in excess of required  repayments,
          less (vi) an amount equal to Capital  Expenditures  of  Borrowers  and
          their respective  Subsidiaries  for such period,  less (vii) an amount
          equal to the sum of all  regularly  scheduled  payments  and  optional
          and/or mandatory payments of principal on Indebtedness of Borrower and
          their Subsidiaries actually made during such period.

     (c)  "Fourth  Amendment"  shall  mean the  Fourth  Amendment  to  Revolving
          Credit,  Term  Loan,  Equipment  Acquisition  Term  Loan and  Security
          Agreement  entered  into as of July __, 2005 by and between  Agent and
          Borrowers.



     (d)  "Fourth  Amendment  Effective  Date" shall have the meaning given such
          term in the Fourth Amendment.

     (e)  "Notice  Regarding  Notes" shall have the meaning  provided in Section
          2.19.

     (f)  "Register" shall have the meaning provided in Section 2.19.

     (g)  "Tender  Offer" shall mean a tender offer with respect to the Parent's
          Common Stock, pursuant to which Parent shall have offered,  subject to
          the terms and conditions  contained in the Tender Offer Documents,  to
          purchase shares of the Parent's  outstanding Common Stock at a maximum
          price of $4.50 per  share  and  $4,500,000  in the  aggregate  for all
          shares so purchased  from existing  shareholders  of the Parent on the
          terms contemplated by the Tender Offer Documents.

     (h)  "Tender Offer Approval Date" shall mean the date upon which all of the
          following  conditions  shall  have  been  and  shall  continue  to  be
          satisfied:  (a) Parent shall have commenced a Tender Offer; (b) Parent
          shall have obtained all consents, approvals, licenses,  authorizations
          and shall have made all filings, recordings and registrations with the
          Securities and Exchange Commission and all applicable state securities
          authorities  which are necessary in accordance with applicable law for
          the Tender Offer, or obtained a valid exemption therefrom;  and (c)(i)
          Parent shall have taken all action  necessary for the valid execution,
          delivery  and  performance  of all Tender Offer  Documents;  (ii) each
          Tender Offer Document shall be a legal,  valid and binding  obligation
          of Parent,  enforceable in accordance  with its terms;  and (iii) each
          Tender Offer Document shall be in full force and effect.

     (i)  "Tender  Offer  Borrowing  Date" shall mean the date  occurring  on or
          within 10  Business  Days  following  the date  upon  which all of the
          following  conditions have been and shall continue to be satisfied and
          in any event on or before  December  31,  2005:  (a) the Tender  Offer
          Approval Date shall have occurred; and (b) all conditions set forth in
          Section 3 of the Fourth Amendment shall have been satisfied.

     (j)  "Tender  Offer  Documents"  shall  mean  all  of  the  agreements  and
          documents  governing,  or relating to, the Tender  Offer  Transaction,
          together   with  all   schedules,   exhibits,   annexes,   amendments,
          supplements or modifications thereto.

     (k)  "Tender  Offer   Transaction"  shall  mean,   collectively,   (i)  the
          commencement  of the  Tender  Offer,  (ii) the  purchase  of shares of
          Parent's  Common Stock  pursuant to the Tender Offer and in accordance
          with  the  Tender  Offer  Documents,  and  (iii)  the  payment  of all
          reasonable fees and expenses in connection with the foregoing.

     (ii) The following definitions are amended as follows:



     (a)  The definition of "Commitment" and  "Commitments" is amended to delete
          the phrase "(v) with respect to the Equipment  Acquisition  Term Loan,
          as to any Equipment  Acquisition Term Lender, the aggregate commitment
          of such  Equipment  Acquisition  Term  Lender  to fund  the  Equipment
          Acquisition  Term  Loan,  as set  forth on  Schedule  A or in the most
          recent  Lender   Addition   Agreement   executed  by  such   Equipment
          Acquisition  Term Lender,  (vi) as to all Equipment  Acquisition  Term
          Lenders,  the aggregate  commitment of all Equipment  Acquisition Term
          Lenders to fund the Equipment  Acquisition  Term Loan,  and (vii)" set
          forth  therein and to  substitute  the following in place thereof "and
          (v)".

     (b)  The  definition  of "Loan" and "Loans" is amended to delete the phrase
          "the Equipment  Acquisition  Term Loan and all Draws  thereunder," set
          forth therein.

     (c)  The  definition  of "Pro Rata  Share" is  amended to delete the phrase
          "(c) with  respect  to  matters  relating  to a  particular  Equipment
          Acquisition  Term Loan of a Equipment  Acquisition  Term  Lender,  the
          percentage  obtained  by  dividing  (i) the  aggregate  amount  of the
          portion of the  outstanding  Equipment  Acquisition  Term Loan made by
          such Lender by (ii) the aggregate amount of the outstanding  Equipment
          Acquisition  Term Loan,  and (d)" set forth  therein and to substitute
          the following in place thereof: "and (c)".

     (d)  The definition of "Requisite  Lenders" is amended to delete the phrase
          "(c) with respect to matters  relating to Equipment  Acquisition  Term
          Lenders,   Equipment   Acquisition   Term  Lenders  holding  or  being
          responsible  for 51% of more of the sum of the  outstanding  Equipment
          Acquisition  Term Loan,  and (d)" set forth  therein and to substitute
          the following in place thereof: " and (c)".

     (e)  The  definition of "Term" is deleted in the entirety and the following
          is substituted in place thereof:

     "Term" shall mean the period  commencing  on the Closing Date and ending on
July ___,  2008 [date shall be three years from the closing  date of this Fourth
Amendment].

     (f)  The definition of "Termination Fee" is deleted in the entirety and the
          following is substituted in place thereof:

          "Termination Fee" shall mean an amount equal to (i) three percent (3%)
          of  $4,000,000  if  the  event  giving  rise  to  the  payment  of the
          Termination  Fee  occurs  during  the  period  from  Fourth  Amendment
          Effective Date through the first  anniversary of the Fourth  Amendment
          Effective  Date and (ii) two percent (2%) of  $4,000,000  if the event
          giving rise to the payment of the  Termination  Fee occurs  during the
          period from the first  anniversary of the Fourth  Amendment  Effective
          Date up to the second  anniversary of the Fourth  Amendment  Effective
          Date.

          (iii) The following definitions are deleted in the entirety:

               (a) Draws;

               (b) Draw Notice;

               (c) Equipment Acquisition Term Lenders;



               (d) Equipment Acquisition Term Loan;

               (e) Equipment Acquisition Term Note;

               (f) Initial Draw; and

               (g) Maximum Equipment Acquisition Term Loan Amount.

     SECTION 2. Fourth  Amendment  Effective Date. Upon receipt by Agent of each
of the following,  this  Amendment  shall be deemed to be effective (the "Fourth
Amendment Effective Date"):

     (a) An original of this Amendment duly executed by each Borrower, and Agent
shall have accepted and executed this Amendment;

     (b) Evidence  satisfactory to Agent that the Life Insurance  Policy remains
in full force and effect and that the  Collateral  Assignment of Life  Insurance
has been accepted by and duly recorded on the books and records of the insurance
company that issued the Life Insurance Policy;

     (c) Agent  shall have  received  all fees,  charges  and  expenses  due and
payable to Agent and Lenders pursuant to this Amendment;

     (d)  Agent  shall  have  received  a written  opinion  of  counsel  for the
Borrowers  in form  and  content  satisfactory  to the  Agent  in its  Permitted
Discretion,  addressed to the Agent and its counsel,  and covering  such matters
related  to the  transactions  contemplated  hereby  as the  Agent  may  request
(including,  without  limitation,  as to authority,  existence,  incumbency  and
enforceability);

     (e)  Borrowers  shall have  delivered to Agent  updated,  true and accurate
amended and restated  disclosure  schedules to the  Agreement  (the "Amended and
Restated Disclosure Schedules"), which Amended and Restated Disclosure Schedules
shall be in form and substance satisfactory to Agent in its sole discretion; and

     (f) Agent shall have received a certificate  of the corporate  secretary or
assistant  secretary of each Borrower  dated as of the date of this Amendment as
to the incumbency and signature of the Persons  executing this Fourth  Amendment
and the Loan Documents on behalf of such Borrower,  in the form attached  hereto
as Exhibit 2(f).

     SECTION 3.  Conditions  Subsequent.  Borrowers  shall  deliver to Agent the
following documents and other items, each,  satisfactory (in form and substance,
as  applicable)  to  Agent in  Agent's  sole  discretion,  duly  executed  where
appropriate  by  authorized  representatives  of Borrowers and all other parties
thereto, as the case may be, on or before the dates set forth below (any failure
by the  Borrowers to fully and timely  satisfy any of the  conditions  set forth
below shall constitute an Event of Default):

     (a) On or before August 15, 2005, Borrowers shall deliver to Agent updated,
true and  accurate  disclosure  schedules  to the  Agreement  (the  "Amended and
Restated Disclosure Schedules"), which Amended and Restated Disclosure Schedules
must be in form and  substance  satisfactory  to  Agent in its sole  discretion.
Nothing  herein or in the Amended and  Restated  Disclosure  Schedules  shall be
deemed to  constitute a waiver of any breach or Default or Event of Default that
may arise as a result of the matters disclosed therein. In addition, the Amended
and Restated  Disclosure  Schedules may be amended or  supplemented by Borrowers
upon  delivery  to  Agent of such  amendments  or  supplements  and,  except  as
expressly provided  otherwise in the Agreement,  the written approval thereof by
Agent, provided that any such amendment or supplement to the schedules shall not
be deemed to  constitute  a waiver of any  breach or Default or Event of Default
that may arise as a result of the matters disclosed therein.



     (b) On the Tender Offer  Borrowing  Date,  Borrowers shall deliver to Agent
all of the following:

     (i) a  Borrowing  Certificate  for the  Term  Loan in  form  and  substance
satisfactory to Agent, and attached hereto as Exhibit 3(i) and all conditions to
lending set forth in Section 4.2 of this Agreement shall have been satisfied;

     (ii) a  written  opinion  of  counsel  for  Borrowers  in form and  content
satisfactory  to Agent in its Permitted  Discretion,  addressed to the Agent and
its counsel, and covering such matters related to the transactions  contemplated
by the Tender Offer  Transaction  as the Agent may request,  including,  without
limitation,  as to the  following:  (a) the validity and  enforceability  of all
Tender   Offer  Documents   and  the Tender  Offer   Transaction;  (b)  Parent's
receipt of all consents,  approvals,  licenses and  authorizations  and Parent's
filing of all  recordings,  registrations  and documents with the Securities and
Exchange  Commission and all applicable state securities  authorities  which are
necessary in accordance with applicable law for the Tender Offer Transaction (or
Parent's receipt of a valid exemption therefrom);  (c) that all of the Tender
Offer Documents comply as to form in all material respects with the requirements
of the Securities Exchange Act of 1934, as amended and the applicable rules and
regulations of the commission thereunder;

     (iii) true and correct copies of the Tender Offer Documents,  and all terms
and conditions thereof shall be satisfactory to the Agent; and

     (iv) a compliance certificate of Borrowers' chief financial officer in form
satisfactory to Agent,  together with such additional  documents and information
as Agent may request, in its Permitted Discretion,  stating that such person has
reviewed  the  relevant  terms of the Loan  Documents  and that before and after
giving  effect  to  the  Tender  Offer  Borrowing  Date  and  the  Tender  Offer
Transaction:  (a) no Default or Event of Default has occurred or is  continuing;
(b)  Borrowers  have  Excess  Availability  plus  unencumbered  cash in  deposit
accounts  subject to Account  Control  Agreements  in favor of Agent of at least
$1,000,000;  (v) Borrowers  have EBITDA for the twelve (12)  consecutive  months
ending  on such date of at least  $3,500,000;  and (d) the  representations  and
warranties  contained in the Loan Documents are true and correct in all material
respects.

     SECTION  4.  Agreement  in Full  Force  and  Effect as  Amended.  Except as
specifically amended hereby, the Agreement and other Loan Documents shall remain
in full force and effect and hereby are  ratified  and  confirmed as so amended.
This Amendment shall not constitute a novation,  satisfaction and accord,  cure,
release and/or  satisfaction of the Agreement  and/or other Loan Documents,  but
shall constitute an amendment  thereof.  The parties hereto agree to be bound by
the terms and  conditions of the Agreement and Loan Documents as amended by this
Amendment, as though such terms and conditions were set forth herein and therein
in full.  Each  reference  in the  Agreement to "this  Agreement,"  "hereunder,"
"hereof,"  "herein" or words of similar  import shall mean and be a reference to
the Agreement as amended by this Amendment,  and each reference herein or in any
other Loan Document or any other  document or instrument to the Agreement  shall
mean and be a  reference  to the  Agreement  as  amended  and  modified  by this
Amendment.  Each  reference in the Agreement  and/or other Loan Documents or any
other  document or instrument to any Loan  Documents or words of similar  import
shall mean and be a reference to the Loan Documents as amended hereby.



     SECTION 5. Representations.

     Each Borrower hereby  represents and warrants to Agent as follows as of the
date  hereof,  as of the Fourth  Amendment  Effective  Date and as of the Tender
Offer Borrowing Date: (i) it is duly incorporated,  validly existing and in good
standing under the laws of its jurisdiction of organization; (ii) the execution,
delivery  and  performance  by it of this  Amendment  to which it is a party are
within its powers,  have been duly  authorized,  and do not  contravene  (A) its
articles  of  incorporation  or  other  organizational  documents,  or  (B)  any
applicable law; (iii) no consent, license, permit, approval or authorization of,
or registration,  filing or declaration with any Governmental Authority or other
Person is required in  connection  with the  execution,  delivery,  performance,
validity  or  enforceability  of this  Amendment  by or  against  it;  (iv) this
Amendment  has been  duly  executed  and  delivered  by it;  (v) this  Amendment
constitutes its legal, valid and binding  obligations  enforceable against it in
accordance with its terms, except as enforceability may be limited by applicable
bankruptcy, insolvency, reorganization, moratorium or similar laws affecting the
enforcement of creditors'  rights generally or by general  principles of equity;
(vi) it is in compliance with all covenants and agreements in the Loan Documents
and it is not in default  under the  Agreement or any other Loan Document and no
Default or Event of Default  exists,  has  occurred and is  continuing  or would
result by the execution,  delivery or performance of this Amendment,  including,
without limitation,  any violation or breach of or Event of Default with respect
to  Annex I of the  Agreement,  including  as  amended  hereby,  and  (vii)  the
representations  and  warranties  contained in the Loan  Documents  are true and
correct  in all  material  respects  as of the date  hereof and as of the Fourth
Amendment  Effective  Date  as if made  on the  date  hereof,  except  for  such
representations and warranties limited by their terms to a specific date.

     SECTION 6. EACH  BORROWER  HEREBY  ACKNOWLEDGES  AND AGREES  THAT IT HAS NO
DEFENSE, COUNTERCLAIM,  OFFSET, CROSS-COMPLAINT,  CLAIM OR DEMAND OF ANY KIND OR
NATURE WHATSOEVER THAT CAN BE ASSERTED TO REDUCE OR ELIMINATE ALL OR ANY PART OF
ITS LIABILITY TO REPAY THE OBLIGATIONS OR TO SEEK AFFIRMATIVE  RELIEF OR DAMAGES
OF ANY  KIND  OR  NATURE  FROM  AGENT  AND THE  LENDERS.  EACH  BORROWER  HEREBY
VOLUNTARILY AND KNOWINGLY RELEASES AND FOREVER DISCHARGES AGENT, THE LENDERS AND
EACH OF THEIR RESPECTIVE PREDECESSORS, AGENTS, EMPLOYEES, SUCCESSORS AND ASSIGNS
(COLLECTIVELY,  THE  "RELEASED  PARTIES")  FROM ALL  POSSIBLE  CLAIMS,  DEMANDS,
ACTIONS,  CAUSES OF ACTION, DAMAGES, COSTS, EXPENSES AND LIABILITIES WHATSOEVER,
WHETHER  KNOWN  OR  UNKNOWN,   ANTICIPATED   OR   UNANTICIPATED,   SUSPECTED  OR
UNSUSPECTED,  FIXED,  CONTINGENT OR CONDITIONAL,  OR AT LAW OR IN EQUITY, IN ANY
CASE  ORIGINATING  IN WHOLE OR IN PART ON OR BEFORE THE DATE THIS  AMENDMENT  IS
EXECUTED  THAT ANY  BORROWER  MAY NOW OR  HEREAFTER  HAVE  AGAINST THE  RELEASED
PARTIES, IF ANY,  IRRESPECTIVE OF WHETHER ANY SUCH CLAIMS ARISE OUT OF CONTRACT,
TORT,  VIOLATION OF LAW OR  REGULATIONS,  OR OTHERWISE,  AND THAT ARISE FROM ANY
LOANS, THE EXERCISE OF ANY RIGHTS AND REMEDIES UNDER THE AGREEMENT OR OTHER LOAN
DOCUMENTS,  AND/OR  NEGOTIATION FOR AND EXECUTION OF THIS AMENDMENT,  INCLUDING,
WITHOUT LIMITATION, ANY CONTRACTING FOR, CHARGING, TAKING, RESERVING, COLLECTING
OR RECEIVING INTEREST IN EXCESS OF THE HIGHEST LAWFUL RATE APPLICABLE.

     SECTION 7. Miscellaneous.



     (a) The execution,  delivery and effectiveness of this Amendment shall not,
except  as  expressly   provided  herein,  be  deemed  to  be  an  amendment  or
modification  of, or operate as a waiver of, any  provision of the  Agreement or
any other Loan Document or any right, power or remedy of Agent, nor constitute a
waiver of any  provision  of the  Agreement or any other Loan  Document,  or any
other document,  instrument and/or agreement executed or delivered in connection
therewith or of any Default or Event of Default under any of the  foregoing,  in
each case  whether  arising  before  or after the date  hereof or as a result of
performance  hereunder  or  thereunder.  This  Amendment  shall not preclude the
future  exercise of any right,  remedy,  power or  privilege  available to Agent
whether under the Agreement, other Loan Documents, at law or otherwise.

     (b) This Amendment may be executed in any number of counterparts (including
by  facsimile),  and by the different  parties  hereto or thereto on the same or
separate  counterparts,  each  of  which  shall  be  deemed  to be  an  original
instrument  but  all of  which  together  shall  constitute  one  and  the  same
agreement.  Each  party  agrees  that  it  will be  bound  by its own  facsimile
signature and that it accepts the facsimile  signature of each other party.  The
descriptive  headings of the various sections of this Amendment are inserted for
convenience  of reference  only and shall not be deemed to affect the meaning or
construction  of any of the provisions  hereof or thereof.  Whenever the context
and  construction  so require,  all words herein in the singular  number  herein
shall be  deemed  to have  been  used in the  plural,  and vice  versa,  and the
masculine  gender  shall  include the  feminine  and neuter and the neuter shall
include the masculine and feminine.

     (c)  This  Amendment  may  not  be  changed,  amended,   restated,  waived,
supplemented,  discharged,  canceled, terminated or otherwise modified orally or
by any  course  of  dealing  or in any  manner  other  than as  provided  in the
Agreement or the applicable  Loan Document.  This Amendment  shall be considered
part of the Agreement  and shall be a Loan  Document for all purposes  under the
Agreement and other Loan Documents.

     (d) This Amendment,  the Agreement,  and the Loan Documents  constitute the
final,  entire agreement and  understanding  between the parties with respect to
the subject matter hereof and thereof and may not be contradicted by evidence of
prior,  contemporaneous or subsequent oral agreements  between the parties,  and
shall be binding upon and inure to the benefit of the  successors and assigns of
the parties hereto and thereto.  There are no unwritten oral agreements  between
the  parties  with  respect to the subject  matter  hereof and  thereof.  If any
provision of this Amendment is adjudicated to be invalid under  applicable  laws
or  regulations,  such  provision  shall be  inapplicable  to the extent of such
invalidity  without affecting the validity or enforceability of the remainder of
this Amendment which shall be given effect so far as possible.

     (e) THIS AMENDMENT AND THE RIGHTS AND OBLIGATIONS OF THE PARTIES  HEREUNDER
AND THEREUNDER  SHALL BE GOVERNED BY AND CONSTRUED AND INTERPRETED IN ACCORDANCE
WITH THE  CHOICE  OF LAW  PROVISIONS  SET  FORTH IN THE  AGREEMENT  AND SHALL BE
SUBJECT TO THE WAIVER OF JURY TRIAL AND NOTICE PROVISIONS OF THE AGREEMENT.

     (f) No Borrower may assign,  delegate or transfer this  Amendment or any of
its rights or obligations  hereunder or thereunder and any delegation,  transfer
or assignment in violation hereof shall be null and void. No rights are intended
to be created  under this  Amendment  for the benefit of any third party  donee,
creditor or  incidental  beneficiary  of any  Borrower or any other Person other
than  Agent  and each  Lender.  Nothing  contained  in this  Amendment  shall be
construed  as a  delegation  to  Agent  of  Borrowers'  duties  of  performance,
including, without limitation, any duties under any account or contract in which
Agent has a security  interest or Lien.  This  Amendment  shall be binding  upon
Borrowers and Agent and Lenders and their  respective  successors  and permitted
assigns.  Agent's and  Lenders'  ability to assign,  sell or transfer all of any
part of this Amendment and shall be governed by the Agreement.





(g) Each Borrower hereby (i) consents to the execution and delivery of this
Amendment by the other Borrowers, (ii) agrees that this Amendment and shall not
limit or diminish the obligations of the subject Borrower under the Loan
Documents, (iii) reaffirms its obligations under each of the Loan Documents to
which it is a party, and (iv) agrees that each of such Loan Documents remain in
full force and effect and are hereby ratified and confirmed. All representations
and warranties made in this Amendment and shall survive the execution and
delivery of this Amendment and no investigation by Agent shall affect such
representations or warranties or the right of Agent to rely upon them.

(h) Each Borrower shall execute and deliver such other documents, certificates
and/or instruments and take such other actions as Agent may reasonably request
in order more effectively to consummate the transactions contemplated hereby.

                      [SIGNATURES APPEAR ON FOLLOWING PAGE]











                                SIGNATURE PAGE TO
           FOURTH AMENDMENT TO REVOLVING CREDIT, TERM LOAN, EQUIPMENT
                  ACQUISITION TERM LOAN AND SECURITY AGREEMENT

     IN WITNESS  WHEREOF,  the parties  have caused  this  Fourth  Amendment  To
Revolving  Credit,  Term  Loan,  Equipment  Acquisition  Term Loan And  Security
Agreement to be executed by their respective officers thereunto duly authorized,
as of the date  first  written  above to be  effective  on and as of the  Fourth
Amendment Effective Date.

BORROWERS:                       ADVANCED NUTRACEUTICALS, INC.,
                                 a Texas corporation


                                 By:_________________________________
                                 Name:
                                 Title:

                                 BACTOLAC PHARMACEUTICAL, INC.,
                                 a Delaware corporation


                                 By:_________________________________
                                 Name:
                                 Title:

                                 NIB, INC. (f/k/a/ ANI PHARMACEUTICALS, INC.),
                                 a Mississippi corporation


                                 By:_________________________________
                                 Name:
                                 Title:

AGENT AND LENDER:

                                 CAPITALSOURCE FINANCE LLC


                                 By:_________________________________
                                 Name:
                                 Title:











                                   SCHEDULE A
                               Lenders/Commitments

Revolving Lenders                                           Revolving Commitment
- --------------------------------------------------------------------------------
CapitalSource Finance LLC                                        $2,500,000
4445 Willard Avenue, 12th Floor
Chevy Chase, Maryland 20815
Attention:  Corporate Finance Group, Portfolio Manager
Telephone:  (301) 841-2700
FAX:  (301) 841-2360
E-Mail: rdailey@capitalsource.com

Wire Instructions:

Bank:                      Bank of America, Baltimore, MD
Account:                   003930559738
ABA:                       052001633
Account Name:              CapitalSource Funding LLC
Reference:                 Advanced Nutraceuticals, Inc.
- --------------------------------------------------------------------------------
Total:                                                           $2,500,000
================================================================================



Term Lenders                                                Term Loan Commitment
- --------------------------------------------------------------------------------
CapitalSource Finance LLC                                        $4,000,000
4445 Willard Avenue, 12th Floor
Chevy Chase, Maryland 20815
Attention:  Corporate Finance Group, Portfolio Manager
Telephone:  (301) 841-2700
FAX:  (301) 841-2360
E-Mail:  rdailey@capitalsource.com

Wire Instructions:

Bank:                      Bank of America, Baltimore, MD
Account:                   003930559738
ABA:                       052001633
Account Name:              CapitalSource Funding LLC
Reference:                 Advanced Nutraceuticals, Inc.
- --------------------------------------------------------------------------------
Total:                                                           $4,000,000
================================================================================













                                     ANNEX I
                                     -------

                               FINANCIAL COVENANTS
                               -------------------



1)   Fixed Charge Coverage Ratio

     The Fixed Charge  Coverage Ratio of the Borrowers for the twelve (12) month
period  ending on any date set forth in the table  below  shall not be less than
the minimum ratio set forth in the table below opposite such date:

- ------------------------------------------------------------ ----------------
            Date                                             Minimum Ratio
- ------------------------------------------------------------ ----------------
December 31, 2005                                            1.30 to 1.00
- ------------------------------------------------------------ ----------------
March 31, 2006                                               1.30 to 1.00
- ------------------------------------------------------------ ----------------
June 30, 2006                                                1.30 to 1.00
- ------------------------------------------------------------ ----------------
September 30, 2006                                           1.30 to 1.00
- ------------------------------------------------------------ ----------------
December 31, 2006                                            1.40 to 1.00
- ------------------------------------------------------------ ----------------
March 31, 2007                                               1.40 to 1.00
- ------------------------------------------------------------ ----------------
June 30, 2007                                                1.40 to 1.00
- ------------------------------------------------------------ ----------------
September 30, 2007                                           1.40 to 1.00
- ------------------------------------------------------------ ----------------
December 31, 2007 and the last day of each
calendar  1.50 to 1.00 quarter thereafter
- ------------------------------------------------------------ ----------------


2)   Senior Leverage Ratio

     The Senior Leverage Ratio of the Borrowers for the twelve (12) month period
ending on any date set forth in the table below shall not be more than the ratio
set forth in the table below opposite such date:

- ----------------------------------------------------------------------------
           Date                           Maximum Senior Leverage Ratio
- ----------------------------------------------------------------------------
December 31, 2005                               2.00 to 1.00
- ----------------------------------------------------------------------------
March 31, 2006                                  2.00 to 1.00
- ----------------------------------------------------------------------------
June 30, 2006                                   1.75 to 1.00
- ----------------------------------------------------------------------------



- ----------------------------------------------------------------------------
September 30, 2006                              1.75 to 1.00
- ----------------------------------------------------------------------------
December 31, 2006                               1.50 to 1.00
- ----------------------------------------------------------------------------
March 31, 2007                                  1.50 to 1.00
- ----------------------------------------------------------------------------
June 30, 2007                                   1.25 to 1.00
- ----------------------------------------------------------------------------
September 30, 2007                              1.25 to 1.00
- ----------------------------------------------------------------------------
December 31, 2007 and the last day of each
calendar  1.00 to 1.00 quarter thereafter
- ----------------------------------------------------------------------------


3)   Capital Expenditure

     Borrowers shall not permit Capital  Expenditures in the aggregate to exceed
$600,000 in Borrowers' fiscal year ending September 30, 2005 and $400,000 in any
fiscal year of the Borrowers thereafter.

4)   Minimum EBITDA

     The EBITDA of the  Borrowers  on a  consolidated  basis for the twelve (12)
month  period  ending on any date set forth in the table below shall not be less
than the minimum amount set forth in the table below opposite such date:

- -----------------------------------------------------------------------------
                   Date                          Minimum EBITDA
- -----------------------------------------------------------------------------
December 31, 2005                                  $3,600,000
- -----------------------------------------------------------------------------
March 31, 2006                                     $3,800,000
- -----------------------------------------------------------------------------
June 30, 2006                                      $3,900,000
- -----------------------------------------------------------------------------
September 30, 2006                                 $4,150,000
- -----------------------------------------------------------------------------
December 31, 2006                                  $4,400,000
- -----------------------------------------------------------------------------
March 31, 2007                                     $4,600,000
- -----------------------------------------------------------------------------
June 30, 2007                                      $4,800,000
- -----------------------------------------------------------------------------
September 30, 2007                                 $5,000,000
- -----------------------------------------------------------------------------
December 31, 2007                                  $5,100,000
- -----------------------------------------------------------------------------





- -----------------------------------------------------------------------------
March 31, 2008                                     $5,200,000
- -----------------------------------------------------------------------------
June 30, 2008 and the last day of each
calendar quarter $5,300,000 thereafter
- -----------------------------------------------------------------------------


5)   Defined Terms

     For purposes of the  covenants  set forth in this Annex I, the terms listed
below shall have the following meanings:

     "Capital  Expenditures" shall mean for Borrowers,  on a consolidated basis,
the sum  (without  duplication)  of all  expenditures  (whether  paid in cash or
accrued  as  liabilities)  that are or are  required  to be  treated  as capital
expenditures under GAAP.

     "EBITDA"  shall  mean for  Borrowers,  on a  consolidated  basis,  the sum,
without duplication,  of the following: Net Income determined in accordance with
GAAP, plus, (a) Interest Expense, (b) taxes on income, (c) depreciation expense,
(d) amortization  expense, (e) all other non-cash and/or  non-recurring  charges
and expenses approved by Agent in its Permitted  Discretion,  excluding accruals
for cash expenses made in the ordinary course of business, and (f) loss from any
sale of assets,  other than sales in the ordinary  course of business,  less (x)
gain  from any sale of  assets,  other  than  sales in the  ordinary  course  of
business, and (y) all non-cash and/or non-recurring income, all of the foregoing
determined in accordance with GAAP.

     "Fixed Charge  Coverage  Ratio" shall mean, for Borrowers on a consolidated
basis, at any date of determination, the ratio of (a) EBITDA, minus non-financed
Capital Expenditures, minus income taxes paid in cash, to (b) Fixed Charges, for
the twelve (12) months then ending taken as one accounting period.

     "Fixed  Charges" shall mean,  the sum of the following for Borrowers,  on a
consolidated basis: (a) Total Debt Service,  (b) dividends and/or  distributions
paid in cash, and (c) cash paid for stock repurchases  and/or redemptions (other
than up to $4,500,000 paid by Parent pursuant to the Tender Offer Transaction).

     "Interest  Expense" shall mean total interest expense  generated during the
period in question  (including  attributable  to  conditional  sales  contracts,
Capital Leases and other title retention  agreements in accordance with GAAP) of
Borrowers on a consolidated  basis with respect to all outstanding  Indebtedness
including  accrued  interest and interest paid in kind and capitalized  interest
but excluding commissions, discounts and other fees owed with respect to letters
of credit and bankers' acceptance  financing,  and net costs under Interest Rate
Agreements.

     "Interest Rate Agreement"  shall mean any interest rate swap, cap or collar
agreement  or other  similar  agreement  or  arrangement  designed  to hedge the
position with respect to interest rates.



     "Net  Income"  shall  mean  the net  income  (or  loss) of  Borrowers  on a
consolidated  basis  for  such  period  taken  as  a  single  accounting  period
determined in conformity with GAAP;  provided,  that there shall be excluded (i)
the  income  (or  loss) of any  Person in which any  other  Person  (other  than
Borrowers) has a joint interest, except to the extent of the amount of dividends
or other  distributions  actually  paid to a Borrower by such Person during such
period,  (ii) the income (or loss) of any  Person  accrued  prior to the date it
becomes a Borrower  or is merged  into or  consolidated  with a Borrower or that
Person's  assets are acquired by a Borrower,  (iii) the income of any Subsidiary
of  Borrowers  to the extent that the  declaration  or payment of  dividends  or
similar  distributions  of that  income  by that  Subsidiary  is not at the time
permitted by operation of the terms of the charter or any agreement, instrument,
judgment,  decree, order, statute, rule or governmental regulation applicable to
that  Subsidiary,  (iv)  compensation  expense  resulting  from the  issuance of
capital stock,  stock options or stock  appreciation  rights issued to former or
current employees,  including officers,  of a Borrower,  or the exercise of such
options or rights, in each case to the extent the obligation (if any) associated
therewith  is not expected to be settled by the payment of cash by a Borrower or
any  Affiliate  thereof,   and  (v)  compensation  expense  resulting  from  the
repurchase of capital stock, options and rights described in clause (iv) of this
definition of Net Income.

     "Senior  Debt"  shall  mean,  at  any  date  of  determination,  the  total
Indebtedness of Borrowers, on a consolidated basis, under the Loan Documents.

     "Senior Debt Leverage  Ratio" shall mean,  for Borrowers on a  consolidated
basis, at any date of determination, the ratio of (i) Senior Debt outstanding on
such date,  to (ii) EBITDA for the  applicable  period then ending  taken as one
accounting period.

     "Total  Debt"  shall  mean,  at  any  date  of  determination,   the  total
Indebtedness  of  Borrowers  on  a  consolidated   basis,   including,   without
limitation,  all Indebtedness  under the Loan Documents and all accrued interest
on the foregoing (including,  without limitation, all interest paid in kind) and
all  Capital  Leases,  but  excluding  current  operating  liabilities.  For all
purposes of this Agreement, the term "Total Debt" shall be calculated to include
(i.e., not net of) discounts,  deductions or allocations  relating or applicable
to or arising from any equity or equity  participation  or fees,  whether  under
GAAP or otherwise.

     "Total Debt Service"  shall mean the sum of (i) scheduled or other required
payments of principal on Total Debt  (excluding the repayment of the note due to
Dr. Reddy so long as such repayment  occurs on or immediately  after the Closing
Date as  permitted  hereunder),  (ii) any other  cash fees due or  payable  with
respect  to,  in  connection  with or on Total  Debt,  and (iii)  cash  Interest
Expense.