EX-99.01 March 4, 2004 RE: Debt Cancellation I, ______________, hereby agree to cancel the accrued wages and vacation owed to me through February 29, 2004 in the amount of $_________. In consideration for canceling this debt, I agree to accept ________ shares of Human BioSystems common stock. I further agree to execute an Investment Letter (debt cancellation) I understand that I am responsible for all taxes when and if due. Agreed to by: ________________________ Accepted by: /s/Harry Masuda __________________________ Harry Masuda, President Human Biosystems