1
Exhibit 10.10
AMENDMENT NO. 4
to the
License Agreement
Effective June 1, 1987
Between
STANFORD UNIVERSITY
and
NEORX CORPORATION
Effective as of July 11, 1997, THE BOARD OF TRUSTEES OF THE LELAND
STANFORD JUNIOR UNIVERITY, a body having corporate powers under the laws of the
State of California ("STANFORD") and NEORX CORPORATION, a Washington
Corporation, having a principal place of business at 410 W. Harrison, Seattle,
Washington 98119 ("NEORX"), agree as follows:
AMENDMENT
2.3 - Paragraph 12.3(a) of the License is hereby amended to read in its
entirety, as follows:
12.3 (a) - Sublicense terms and conditions shall reflect that any
sublicensee shall not further sublicense; provided, however, that
NEORX's proposed sublicensee, JANSSEN PHARMACEUTICA, may further
sublicense provided that notification is sent to STANFORD upon signing
of the sublicense and that any sub-sublicensee may not further
sublicense; and
IN WITNESS WHEREOF, the parties hereto have executed this Amendment No.
4 in duplicate originals by their duly authorized officers or representatives.
THE BOARD OF TRUSTEES NEORX CORPORATION
OF THE LELAND STANFORD
JUNIOR UNIVERSITY
By /s/ [SIGNATURE ILLEGIBLE] By /s/ PAUL G. ABRAMS
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Title Director Technology Licensing Title President & CEO
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Date July 15, 1997 Date 7/11/97
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