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                           CHANGE IN TERMS AGREEMENT


- ------------------- ----------------- ----------------- ----------------
    Principal          Loan Date          Maturity         Loan No.
   $150,000.00         03-03-2009        06-09-2009        930610000
- ------------------- ----------------- ----------------- ----------------


- ----------------- ----------------- ---------------- -----------------
  Call / Coll         Account           Officer          Initials
                                          RK              /s/ RK
- ----------------- ----------------- ---------------- -----------------


           References in the boxes above are for Lender's use only and
                 do not limit the applicability of this document
                 to any particular loan or item. Any item above
                  containing "***" has been omitted due to text
                               length limitations.


Borrower:                                      Lender:
    Amexdrug Corporation; Dermagen, Inc.;         National Bank of California
    Biorx Pharmaceuticals, Inc.; Royal            Corporate Banking Department
    Health Care, Inc.; and Allied Med Inc.        145 South Fairfax Avenue
    8909 West Olympic Boulevard, Suite 208        Los Angeles, CA 90036
    Beverly Hills, CA 90211


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Principal Amount: $150,000.00                  Date of Agreement:  March 3, 2009

DESCRIPTION OF EXISTING INDEBTEDNESS: The Promissory Note dated June 23, 2008 in
the amount of $150,000.00.

The interest rate floor on the Note is hereby decreased from 7.500% to 6.000%.

CONTINUING VALIDITY. Except as expressly changed by this Agreement, the terms of
the original  obligation or obligations,  including all agreements  evidenced or
securing  the  obligation(s),  remain  unchanged  and in full force and  effect.
Consent  by Lender to this  Agreement  does not waive  Lender's  right to strict
performance of the  obligation(s)  as changed,  nor obligate  Lender to make any
future change in terms. Nothing in this Agreement will constitute a satisfaction
of the obligation(s).  It is the intention of Lender to retain as liable parties
all makers or endorsers of the original  obligation(s),  including accommodation
parties, unless a party is expressly released by Lender in writing. Any maker or
endorser, including accommodation makers, will not be released by virtue of this
Agreement.  If any person who signed the original  obligation does not sign this
Agreement below,  then all persons signing below acknowledge that this Agreement
is  given  conditionally,  based  on  the  representation  to  Lender  that  the
non-signing  party  consents to the changes and  provisions of this Agreement or
otherwise  will not be  released  by it.  This  waiver  applies  not only to any
initial  extension,  modification  or release,  but also to all such  subsequent
actions.

PRIOR TO SIGNING THIS AGREEMENT, BORROWERS READ AND UNDERSTOOD ALL PROVISIONS OF
THIS AGREEMENT. BORROWERS AGREES TO THE TERMS OF THE AGREEMENT.

BORROWER:

    AMEXDRUG CORPORATION

    By:     /s/ Jack N. Amin
       ----------------------------------------------------------------
         Jack N. Amin, President/Secretary of Amexdrug Corporation

    DERMAGEN, INC.

    By:     /s/ Jack N. Amin
       ----------------------------------------------------------------
         Jack N. Amin, President/Secretary of Dermagen, Inc.

    BIORIX PHARMACEUTICALS, INC.

    By:     /s/ Jack N. Amin
       ----------------------------------------------------------------
         Jack N. Amin, President/Secretary of Biorx Pharmaceuticals, Inc.

    ROYAL HEALTH CARE, INC.

    By:     /s/ Jack N. Amin
       ----------------------------------------------------------------
         Jack N. Amin, President/Secretary of Royal Health Care, Inc.

    ALLIED MED INC.

    By:     /s/ Jack N. Amin
       ----------------------------------------------------------------
         Jack N. Amin, President/Secretary of Allied Med Inc.

PRIOR TO SIGNING THIS  AGREEMENT,  GUARANTORS READ AND UNDERSTOOD ALL PROVISIONS
OF THIS AGREEMENT. GUARANTORS AGREES TO THE TERMS OF THE AGREEMENT.


         /s/ Jack N. Amin
    ----------------------------------------------------------
         Jack N. Amin, Individually


         /s/ Nora Y. Amin
    ----------------------------------------------------------
         Nora Y. Amin, Individually








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