As filed with the Securities  and Exchange  Commission on February 24, 2000
Registration No. 333-30130

                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                           ---------------------------
                                   FORM S-3/A

                                       ON

                                    FORM S-2

                             REGISTRATION STATEMENT

                                      UNDER

                           THE SECURITIES ACT OF 1933
                           ---------------------------

                           ACCENT COLOR SCIENCES, INC.
             (Exact Name of Registrant as Specified in its Charter)
                           ---------------------------


                                                                                         
(State or other Jurisdiction of    (Address, including Zip Code, and Telephone       (I.R.S. Employer
  Incorporation or Organization)   Number, including Area Code, of Registrant's   Identification Number)
                                          Principal Executive Offices)

            CONNECTICUT                    800 Connecticut Boulevard                   06-1380314
                                      East Hartford, Connecticut, 06108
                                                (860) 610-4000

                           ---------------------------
 (Name, Address, including Zip Code, and Telephone Number, including Area Code, of Agent for Service)



                                              
            Charles E. Buchheit                                   Copy to:
                                                                  --------
 President and Chief Executive Officer                    Willard F. Pinney, Jr.
      Accent Color Sciences, Inc.                Murtha, Cullina, Richter and Pinney, LLP
       800 Connecticut Boulevard                 CityPlace I185 Asylum Street, 29th Floor
    East Hartford, Connecticut 06108                 Hartford, Connecticut 06103-3469
             (860) 610-4000                                   (860) 240-6000


                         ---------------------------
         Approximate date of the start of proposed sale to the public: From time
to time after this registration statement becomes effective.

If any of the  securities  being  registered on this Form are to be offered on a
delayed or continuous  basis  pursuant to Rule 415 under the  Securities  Act of
1933 check the following box.[X]

If the  registrant  elects to  deliver  its  latest  annual  report to  security
holders, or a complete and legible facsimile thereof,  pursuant to Item 11(a)(1)
of this Form, check the following box. [X]



If this Form is filed to register additional securities for an offering pursuant
to Rule 462(b) under the Securities Act, please check the following box and list
the  Securities  Act  registration  statement  number of the  earlier  effective
registration statement for the same offering. [ ]

If this Form is a  post-effective  amendment filed pursuant to Rule 462(c) under
the  Securities  Act,  check  the  following  box and  list the  Securities  Act
registrations  statement number of the earlier effective  registration statement
for the same offering. [ ]

If delivery  of the  prospectus  is  expected  to be made  pursuant to Rule 434,
please check the following box. [ ]

                         CALCULATION OF REGISTRATION FEE



- ----------------------- ----------------------- ------------------ --------------------- --------------------
 Title of each class         Amount to be       Proposed maximum     Proposed maximum         Amount of
 of securities to be          registered         offering price     aggregate offering    registration fee
      registered                                   per unit(1)            price
                                                                                      
- ----------------------- ----------------------- ------------------ --------------------- --------------------

common stock,
no par value per              12,418,750             $.8925            $11,083,734          $2,926.10(2)
        share                   shares
- ----------------------- ----------------------- ------------------ --------------------- --------------------


(1) Estimated in accordance  with Rule 457(c) under the  Securities Act of 1933,
solely  for the  purpose  of  calculating  the  registration  fee based upon the
average  of the  high  and low  sale  prices  reported  on the  Over-the-Counter
Bulletin Board system on February 7, 2000.

(2) Fee paid  previously in connection with the  registration  statement on Form
S-3 filed on February 11, 2000 (file no. 333-30130).

The registrant amends this  registration  statement on such date or dates as may
be  necessary  to delay its  effective  date until the  registrant  shall file a
further amendment which  specifically  states that this  registration  statement
shall  thereafter  become  effective  in  accordance  with  Section  8(a) of the
Securities  Act of  1933  or  until  the  registration  statement  shall  become
effective on the date as the  Commission,  acting pursuant to said Section 8(a),
may determine.



The  information  in this  prospectus is not complete and may be changed.  These
securities  may not be sold  until the  registration  statement  filed  with the
Securities and Exchange Commission is effective. This prospectus is not an offer
to sell nor does it seek an offer to buy these  securities  in any  jurisdiction
where the offer or sale is not permitted.

                                   PROSPECTUS

                        12,418,750 SHARES OF COMMON STOCK

                           ACCENT COLOR SCIENCES, INC.

                           ---------------------------

         This  prospectus  relates  to  the  registration  for  resale  of up to
12,418,750  shares  of common  stock of Accent  Color  Sciences,  Inc.  that are
offered by  certain of our  shareholders  named in this  prospectus.  The shares
offered for sale are issuable upon  conversion of some or all of the outstanding
shares  of our  Series C  Convertible  Preferred  Stock or have  been  issued in
connection with a private placement of our common stock or are issuable upon the
exercise  of  certain  warrants  that  we  have  granted.  Please  see  "Selling
Stockholders."

         We will not  receive  any of the  proceeds  from sales of the shares of
common  stock by the selling  stockholders,  all of which will go to the selling
stockholders.

         Our common stock is traded on the  Over-the-Counter  Bulletin  Board of
the National  Association of Securities  Dealers,  Inc. under the symbol "ACLR".
The selling  stockholders  may sell their shares of common stock in transactions
reported on the OTC  Bulletin  Board or may offer their  shares for sale through
other public or private transactions. Please see "Plan of Distribution."

         On February 22, 2000,  the last reported sale price of our common stock
as reported on the OTC Bulletin Board was $.94 per share.

                           ---------------------------

         The shares of common  stock  offered  hereby  involve a high  degree of
risk.  You should  purchase  shares only if you can afford a complete  loss. See
"Risk Factors"  beginning on page 2 for a discussion of certain factors that you
should consider before you purchase any shares of our common stock.

         Neither the Securities and Exchange Commission nor any state securities
commission has approved or disapproved of these securities or determined if this
prospectus  is truthful or  complete.  Any  representation  to the contrary is a
criminal offense.

            The date of this prospectus is __________________, 2000.



                                TABLE OF CONTENTS

                                                                           PAGE

About Accent Color Sciences, Inc..............................................2
Risk Factors..................................................................2
Forward Looking Statements...................................................12
Recent Developments..........................................................12
Where You Can Find More Information..........................................14
Documents We Incorporate By Reference .......................................14
Selling Stockholders ........................................................15
Use of Proceeds..............................................................19
Plan of Distribution ........................................................20
Description of Our Securities................................................22
Legal Matters ...............................................................25
Experts .....................................................................25
Index to Exhibits............................................................27


                                       1


                        ABOUT ACCENT COLOR SCIENCES, INC.

         We design, manufacture and sell innovative, high-speed, highlight color
printing systems ("Truecolor Systems") for integration with digital, high-speed,
monochrome printers and also sell related consumables.  Highlight color printing
involves  the use of  color  to  enhance  traditional  monochrome  documents  by
accenting critical information, such as a balance due on a billing statement, or
by printing  graphics,  like a company logo.  Truecolor  Systems are designed to
print  highlight  color  in  high-speed,   high-volume  applications  at  a  low
incremental  cost per page without  diminishing  the speed or performance of the
high-speed,  monochrome  host  printer  or  affecting  the end  user's  existing
operational  methods.  They are  capable of printing up to 501 pages per minute,
simultaneously  utilizing up to eight different colors, including custom colors,
to print or highlight fixed or variable data.

         Truecolor  Systems  combine our proprietary  paper handling  technology
with patented ink jet technology from Spectra,  Inc. We currently sell Truecolor
Systems   under   agreements   with  two   original   equipment   manufacturers,
International Business Machines Corporation and Xerox Corporation, for resale by
them as IBM or Xerox products.  We also sell consumables  including standard and
custom color wax-based inks, as well as spare parts used with Truecolor Systems.
We expect that consumables will generate  recurring revenue that we believe will
increase as the installed base and usage of Truecolor Systems increase.

         Accent  Color was  incorporated  under the laws of  Connecticut  in May
1993. Our principal executive offices are located at 800 Connecticut  Boulevard,
East Hartford, Connecticut, 06108. Our telephone number at that address is (860)
610-4000.

                                  RISK FACTORS

         An  investment  in Accent Color common stock  involves a high degree of
risk.  You should  carefully  consider  the  following  risk  factors  and other
information in this  prospectus and the documents we incorporate by reference in
evaluating our company  before you purchase any shares of our common stock.  The
risks we  describe  below  are not the only ones we face.  Additional  risks and
uncertainties,  including  those we do not know  about now or that we  currently
deem immaterial, may also adversely affect our business. If any of the following
risks actually occur, our business, financial condition or results of operations
could be materially  adversely affected.  In this case, the trading price of the
common stock could decline and you may lose all or part of your investment.

                                       2


RISKS RELATED TO OUR BUSINESS

         WE HAVE A LIMITED  OPERATING HISTORY AND HAVE INCURRED LOSSES SINCE OUR
         INCEPTION.  IF WE  CONTINUE TO LOSE MONEY,  OUR  OPERATIONS  MAY NOT BE
         FINANCIALLY VIABLE.

         Accent  Color  was  formed  in May  1993  and has a  limited  operating
history.  We have incurred losses in each year since our founding and incurred a
net loss of $9,769,853 (before imputed dividend on preferred stock) for the year
ended December 31, 1998 and a net loss of $3,973,854 (before imputed dividend on
preferred stock) for the first nine months of 1999. As a result of these losses,
as of September 30, 1999, we had an accumulated  deficit of $51,588,818.  Before
any imputed  dividends or charges related to potentially  beneficial  conversion
features  associated  with the  series C  preferred  stock,  we  expect to incur
quarterly net losses  through at least the second quarter of 2000 and a net loss
for fiscal year 2000.  We cannot  assure you that  thereafter we will be able to
achieve or sustain revenue growth, profitability or positive cash flow on either
a  quarterly  or  annual  basis  or that  profitability,  if  achieved,  will be
sustained.

         The  anticipated  increase  in our  operating  expenses  caused  by any
expansion of our  manufacturing  and marketing  operations could have a material
adverse effect on our operating results if revenue does not increase at an equal
or greater rate.  Also, our expenses for these and other activities are based in
significant part on our expectations regarding future revenue and are fixed to a
large  extent in the short term.  We may not be able to adjust our spending in a
timely manner to compensate for any unexpected revenue shortfalls.

         WE MAY NEED TO  RAISE  ADDITIONAL  CAPITAL  IN THE  FUTURE  TO FUND OUR
         OPERATING AND CAPITAL REQUIREMENTS.

         Since our  inception,  we have raised  additional  funding from time to
time as we have increased our marketing,  sales and service  efforts,  continued
our research and development activities for the enhancement of Truecolor Systems
and increased production of our Truecolor Systems. To date, we have financed our
operations through customer payments, borrowings and the sale of debt and equity
securities.

         Although we experienced a slowdown in shipments of our products  during
the latter half of 1999,  which we believe to be due to year 2000  concerns,  we
have received  contractual orders and commitments for Truecolor Systems from our
original equipment  manufacturer ("OEM") customers of approximately $10 million,
which are deliverable in the year 2000.  These currently  anticipated  levels of
revenue and cash flow are subject to many  uncertainties  and cannot be assured.
Further,  we may change our business plans, or unforeseen events may occur which
might  require us to raise  additional  funds.  The need for, and the amount of,
additional funds we may require will depend on many factors, including

         o the extent and timing of sales of our Truecolor Systems,

                                       3

         o the  cost  associated  with  sales,   marketing  and  customer
           technical support efforts, and

         o our operating results.

         We cannot  assure you that,  if needed,  additional  financing  will be
available,  or available on acceptable  terms. If we are unable to obtain needed
additional  financing or generate  sufficient cash from our  operations,  we may
have  to  reduce  or  eliminate   expenditures  for  research  and  development,
production or marketing of our products, or otherwise curtail or discontinue our
operations.  Any of these  developments  could have a material adverse effect on
our business, financial condition and results of operations.

         WE ARE DEPENDENT ON A SINGLE PRODUCT LINE.

         We do not have a variety of product lines.  We anticipate  that we will
derive  substantially all of our revenue in the foreseeable future from sales of
Truecolor  Systems,  related  consumables  and spare parts to our  principal OEM
customers.  If we are unable to  generate  enough  sales of  Truecolor  Systems,
wax-based  ink  and/or  spare  parts  due to  market  conditions,  manufacturing
difficulties or other reasons, we may be unable to continue our business.  Since
we only  have a single  product  line,  we are  particularly  vulnerable  to the
successful  introduction  of  competitive  products  by  existing  or  potential
competitors, including our OEM customers.

         WE HAVE A LIMITED HISTORY OF PRODUCT MANUFACTURING.

         We have a limited  manufacturing  history and cannot assure that we can
make a  successful  transition  to  high-volume  production.  So  far,  we  have
manufactured  only limited  quantities  of Truecolor  Systems and  manufacturing
costs have approximated the average selling price of a unit. To make a profit we
must  manufacture  our products in enough  quantities  and at acceptable  costs.
Future  production  in  enough  quantities  may  pose  technical  and  financial
challenges for us. Our failure to  successfully  transition and  manufacture our
products at a cost  adequately  below their  selling price could have a material
adverse effect on our business, financial condition and results of operations.

         WE MAY NOT BE ABLE TO SUCCESSFULLY MARKET OUR PRODUCTS.

         Our  products  are  designed  for the  digital,  high-speed  production
printing and  production  publishing  market  segments  that have  traditionally
relied on monochrome print. We cannot assure that we will  successfully  develop
or market our existing or future  products or, if any of these products  achieve
market  acceptance,  that we can grow or even  sustain  market  acceptance.  Any
actual  or  perceived  problems  with  our  products,  whether  or not  they are
significant,  could have a material adverse effect on market acceptance of these
products.  Our existing and  potential  customers may conclude that our products
suffer  from real or  perceived  problems.  Even in the  absence  of any real or
perceived problems, our products may fail to achieve market acceptance.

         A failure of our products to achieve  market  acceptance for any reason
could have a material  adverse effect on our business,  financial  condition and
results of operations.  In addition, the announcement by us or our OEM customers
or competitors of new products

                                       4

and  technologies  could cause  customers  to defer  purchases  of our  existing
products, which could have a material adverse effect on our business,  financial
condition and results of operations.

         WE HAVE A CONCENTRATED  CUSTOMER  BASE,  THEREFORE THE LOSS OF A SINGLE
         CUSTOMER COULD NEGATIVELY AFFECT OUR REVENUES AND OPERATING RESULTS.

         We anticipate that sales of our Truecolor  Systems and consumables to a
limited number of customers will account for  substantially  all of our revenue.
We have existing contracts with two customers IBM and Xerox (as the successor to
Groupe SET). Generally, our customers provide estimates, but not guarantees,  of
their future orders.  We cannot assure you that these  customers will purchase a
significant volume of our products.  A substantial  difference between estimated
orders  and actual  orders by any one of our  customers,  or the  failure of our
customers  to  purchase  a  significant  number of our  products,  could  have a
material  adverse  effect on our  business,  financial  condition and results of
operations.  We cannot  assure  you that our OEM  customers,  including  IBM and
Xerox, or other companies will not compete with us in the future.

         WE RELY ON THIRD PARTY MARKETING, DISTRIBUTION AND SUPPORT.

         A significant  element of our marketing  strategy is to form  alliances
with third parties for the marketing and distribution of our products. We cannot
assure you that

          o    we can  maintain  our  existing  alliances  or form and  maintain
               alliances with other parties;

          o    we  can  satisfy  our  contractual   obligations   with  our  OEM
               customers; or

          o    our OEM customers  will devote  adequate  resources to market and
               distribute our products successfully.

         Since our products are marketed and  distributed  via third  parties we
have:

          o    a limited  ability to interact with the users of our products and
               to observe their experience with our products;

          o    a lack of  control of the  marketing,  distribution  and  support
               efforts of our OEM customers that may make us less  responsive in
               recognizing  and correcting  any problems  experienced by the OEM
               customers or the end users;

          o    a lack of  control as to the  timing of the  introduction  of our
               products; and

          o    less  information  regarding  the amount of  inventory  currently
               available and this may reduce our ability to predict fluctuations
               in revenue due to a surplus or a shortage of inventory.

                                       5

         The  foregoing  results of our reliance on third  parties to market and
distribute our products could have a significant adverse effect on our business,
financial  condition and results of operations.  In addition,  any disruption in
our relationships with IBM or Xerox, or any future customer, may have a material
adverse effect on our ability to  successfully  market our Truecolor  Systems to
customers.

         WE ARE  DEPENDENT ON A SOLE SOURCE  SUPPLIER FOR A KEY COMPONENT OF OUR
         PRODUCTS.

         We are dependent on Spectra, a wholly owned subsidiary of Markem, Inc.,
as our sole source  supplier of ink jet printheads  and the hot melt,  wax-based
inks used by  Truecolor  Systems.  Spectra  has agreed to supply us with ink jet
printheads and wax-based inks under a supply  agreement,  subject to a number of
conditions.  We have an exclusive  right,  under an agreement  with Spectra,  to
supply products  including  Spectra's ink jet printheads in the worldwide market
for printing color on the output from specified high-speed,  monochrome printers
marketed by Xerox,  IBM and certain  other  parties  through  December 31, 2002,
however,  we are  currently  not in  compliance  with  certain  volume  purchase
requirements  necessary to maintain such exclusivity.  Therefore,  Spectra could
terminate our right of  exclusivity,  if it chose to do so, but not our right to
purchase  products from Spectra.  We also have an option to renew this agreement
for an additional  seven year term.  Our reliance on Spectra  involves the risks
that we may

         o        be unable to obtain an adequate supply of required  printheads
                  or inks from  another  supplier  in the event that  Spectra is
                  unable or unwilling to do so; and

         o        have a reduced level of control over the quality,  pricing and
                  timing of delivery of these items.

         As we increase the production of Truecolor Systems, we will become more
reliant upon  Spectra's  ability to  manufacture  and deliver ink jet printheads
under the supply  agreement.  Any  interruption in our ability to obtain Spectra
printheads of an acceptable  quality  within the time frame required by us at an
affordable  cost could result in delays and  increased  costs which would have a
material  adverse  effect on our  business,  financial  condition and results of
operations.

         WE DEPEND ON MAJOR SUBCONTRACTORS AND SUPPLIERS.

         We rely on subcontractors and other parties to manufacture, subassemble
and perform  certain  testing of some  modules and parts of  Truecolor  Systems.
Currently,  our ink jet  printheads  are  manufactured  solely  by  Spectra.  We
currently  perform the final  assembly and testing of various  Truecolor  System
components and of each complete  Truecolor System. We plan to hire other parties
to  manufacture  major  components  and complete  final  assembly and testing of
Truecolor Systems in-house.  If we do not develop  relationships  with, or lose,
these subcontractors or suppliers, or if the subcontractors or suppliers fail to
meet our price, quality, quantity and delivery requirements,  then we may suffer
a material  adverse effect on our business,  financial  condition and results of
operations.
                                       6


         WE ARE RESPONSIBLE FOR PRODUCT  WARRANTIES AND HAVE AGREED TO REPAIR OR
         REPLACE OUR PRODUCTS IF DEFECT RATES ARE EXCESSIVE.

         We  warrant  that  our  Truecolor   Systems  are  free  of  defects  in
workmanship  and materials.  We have also agreed to repair or replace  defective
products  without charge when defect rates are excessive.  We cannot assure that
we will not  experience  more warranty  claims or product  failure rates than we
expected  when we  originally  priced our products  and spare parts.  Any excess
warranty claims or product failure rates could have a material adverse effect on
our business, financial condition and results of operations.

         WE DEPEND ON KEY MANAGEMENT PERSONNEL FOR OUR SUCCESS.

         We are substantially  dependent on the capabilities and services of our
key technical and management  personnel,  some of whom have been instrumental in
developing our products and establishing and maintaining strategic relationships
with our key suppliers and major OEM customers.  These personnel include Richard
J. Coburn, our co-founder and chairman of the board of directors, and Charles E.
Buchheit,  our  president  and chief  executive  officer.  Mr.  Buchheit  has an
employment  agreement with us that expires on April 14, 2001.  Mr.  Buchheit may
terminate his employment relationships with us at any time with no penalty other
than the loss of future compensation.

         The loss or interruption  of the continued  service of, and the failure
to promptly replace, either of these key personnel could significantly delay and
may prevent the achievement of our business objectives.

         In addition,  our future success also depends on our continuing ability
to  identify,  hire,  train and retain  other  highly  qualified  technical  and
managerial personnel. Competition for these employees is intense and increasing.
We may not be able to attract,  assimilate  or retain  qualified  technical  and
managerial  personnel in the future, and the failure of us to do so would have a
material  adverse  effect on our  business,  financial  condition and results of
operations.

RISKS RELATED TO OUR INDUSTRY

         OUR   SUCCESS   DEPENDS  ON  THE   ABILITY  TO  KEEP  PACE  WITH  RAPID
         TECHNOLOGICAL ADVANCES IN THE HIGH-SPEED PRINTER INDUSTRY.

         The high-speed printer industry is characterized by evolving technology
and changing  market  requirements.  Our future  success  depends our ability to
continue  to develop  and  manufacture  new  products  and to  enhance  existing
products.  Consequently,  the  enhancement  of  our  products  is a  development
priority. However, in a new and evolving market, customer preferences can change
rapidly  and  new  technology  could  render  existing  technology  and  product
inventory  obsolete.  Our  failure in  responding  adequately  to changes in our
target  market,  in  developing  or acquiring  new  technology  or  successfully
conforming to market  preferences  could depress sales of our existing  products
and technologies. This may result in declining prices and inventory

                                       7

obsolescence  which  would  have a  material  adverse  effect  on our  business,
financial condition and results of operations.

         OUR FAILURE TO  ADEQUATELY  PROTECT OUR  INTELLECTUAL  PROPERTY  RIGHTS
         COULD HARM OUR BUSINESS.

         Because our business depends on technology,  we believe the maintenance
of our patents,  trademarks,  service marks and other proprietary  rights in our
unpatented  know-how and common law  trademarks  and service marks are important
for our success and competitive position. We have secured three patents from the
U.S. Patent and Trademark office relative to the mechanical  design of our paper
handling  and  color  printing  system,  which  form the  core of the  Truecolor
Systems.  In addition,  we have applied for  additional  U.S. and foreign patent
protection relative to our products.

         Our  efforts  to  detect   misappropriation  of  these  rights  may  be
inadequate to prevent  others,  including our OEM customers,  from imitating our
products and  infringing on our  intellectual  property  rights.  It is possible
that, if challenged,  our  intellectual  property rights may be narrowed or held
invalid by a court of competent jurisdiction. The sale of our copied products by
others could  depress  sales of our products  which could  materially  adversely
impact our business, financial condition and results of operations.

         WE RELY ON THE EFFORTS OF A MAJOR SUPPLIER TO PROTECT ITS  INTELLECTUAL
         PROPERTY RIGHTS.

         We have an exclusive right, under an agreement with Spectra,  to supply
products including Spectra's ink jet printheads to our customers.  To the extent
that wax-based  inks and ink jet  printheads  purchased from Spectra are covered
under  patents or licenses,  we rely on  Spectra's  rights under its patents and
licenses and Spectra's willingness and ability to enforce them. We cannot assure
that  Spectra  will be willing or able to enforce its patents and  maintain  its
licenses  against  third  parties.  Any  unwillingness  or inability to do so by
Spectra  could  have  a  material  adverse  effect  on our  business,  financial
condition and results of operations.

         CLAIMS MADE BY THIRD PARTIES THAT WE INFRINGE THEIR PROPRIETARY  RIGHTS
         COULD RESULT IN INCREASED COSTS.

         We  believe  that our  products  and  technology  do not  infringe  any
existing  proprietary  rights of others.  Third  parties  may,  however,  assert
infringement  claims against us in the future.  We may be unable to successfully
defend against these claims. For example, third party competitors, including our
OEM customers,  could assert rights in our intellectual property rights or claim
that the products we offer have violated their proprietary  rights. In addition,
our competitors may have filed for patent protection that is not as yet a matter
of public knowledge.  Moreover, a court could interpret a third-party's  patents
broadly so as to cover some of our products.

         We could incur substantial costs and diversion of management  resources
with  respect to the  defense  of any claims  relating  to  proprietary  rights,
whether or not the assertion of the claim is valid,  which could have a material
adverse effect on our business,  financial  condition and results of operations.
Furthermore,  parties  making  these

                                       8

claims  could  secure  a  judgment  awarding  substantial  damages,  as  well as
injunctive or other equitable relief,  which could effectively block our ability
to make,  use, sell,  distribute or market its products and services in the U.S.
or abroad. Any unfavorable  judgment could have a material adverse effect on our
business, financial condition and results of operations.

         In the event a claim relating to proprietary  technology or information
is asserted  against us, we may seek licenses of that  intellectual  property in
order to use  technology we need to conduct our  business.  We cannot assure you
that we could obtain a license on commercially  reasonable  terms, if at all, or
that the terms of any offered licenses will be acceptable. The failure to obtain
the necessary  licenses or other rights could preclude the sale,  manufacture or
distribution  of our  products  and,  therefore,  could have a material  adverse
effect on our business, financial condition and results of operations.

         We are required to indemnify  any of our OEM  customers  against  third
party infringement  claims. As a result, our business,  financial  condition and
results  of  operations  could  be  materially  adversely  affected  if any such
infringement claims are asserted against our OEM customers.

         COMPETITION  COULD PREVENT OUR EFFORTS TO ESTABLISH  MARKET  ACCEPTANCE
         FOR OUR PRODUCTS AND HARM OUR BUSINESS.

         Our  competitors  may  be  able  to  develop  products  that  are  more
attractive to customers than our products.  We compete,  in significant part, on
the basis of advanced proprietary technology in the areas of paper handling, ink
jet color  printing and  interface  software  which allows our products to print
variable data, in multiple standard and custom colors at high speeds.

         Competition to supply high-speed color printing is fragmented.  Many of
our competitors and potential  competitors have substantially  greater financial
and technical resources,  longer operating  histories,  greater name recognition
and more  extensive  customer  bases that could be used to gain market  share or
product acceptance. In addition to direct competition from other firms utilizing
high-speed color  technologies,  we face potential direct competition from firms
improving  technologies  used in low-speed to  medium-speed  color  printers and
indirect competition from firms producing pre-printed forms.

         Other companies may introduce products or product improvements based on
new technologies with little or no advance notice.  Manufacturers of high-speed,
monochrome  printers may also, in time,  develop  comparable  or more  effective
color  capability  within  their own  products  which may  render  our  products
obsolete.  There can be no  assurance  that we will be able to  compete  against
future competitors  successfully or that competitive  pressures we face will not
have a material  adverse  effect upon the success of our business and  financial
condition.

         OUR OEM CUSTOMERS MARKET AND SELL OUR PRODUCTS INTERNATIONALLY.

                                       9


        As part of our business strategy, our OEM customers market and sell our
products to end users outside the United States. International sales are subject
to certain inherent risks, including:

          o    unexpected changes in regulatory requirements;

          o    export and import restrictions, tariffs and other trade barriers;

          o    government controls and potential political instability; and

          o    potentially adverse tax consequences.

         Any of the above  factors could have a material  adverse  effect on our
business, financial condition and results of operations.

RISKS RELATED TO THE OFFERING

         WE HAVE A LIMITED  MARKET FOR OUR COMMON  STOCK AND OUR STOCK  PRICE IS
         VOLATILE.

         Our common stock is currently quoted and traded in the over-the-counter
market  on the  "Electronic  Bulletin  Board"  of the  National  Association  of
Securities  Dealers,  Inc  under  the  symbol  "ACLR."  Trading  on the NASD OTC
Bulletin Board is sporadic and can be highly  volatile.  The market price of our
common stock has  fluctuated  in the past and may continue to be volatile in the
future.  As a result of these  factors,  an  investor  will  likely find it more
difficult to sell our stock or to obtain accurate  quotations as to the price of
our stock than if the stock were traded on a national  securities exchange or on
the Nasdaq national market.

         OUR QUARTERLY  OPERATING  RESULTS MAY NOT BE A GOOD INDICATOR OF FUTURE
         RESULTS AND MAY  FLUCTUATE  SIGNIFICANTLY,  WHICH COULD RESULT IN LOWER
         PRICES FOR OUR STOCK.

         We expect our quarterly operating results to fluctuate significantly in
the  future  based  upon a number  of  factors,  some of which are  outside  our
control. As a result, it is possible that our operating results may be below the
expectations  of investors  in some future  period.  If this were to occur,  the
trading price of our common stock would likely decline, perhaps significantly.

         The factors  which  affect  whether  our  operating  results  fluctuate
include:

          o    the volume, timing, delivery and acceptance of customer orders;

          o    the rate of customer and end-user  acceptance of our products and
               the volume or nature of warranty claims;

          o    the market acceptance of host printing systems offered by our OEM
               customers;

                                       10

          o    changes in our pricing  policies or those of our OEM customers or
               competitors;

          o    the relative proportion of printer and consumables sales;

          o    the  timely  availability  of  sufficient  volume of sole  source
               components;

          o    fluctuations in our research and development expenditures;

          o    the  availability  of financing  arrangements  for certain of our
               customers; and

          o    economic  conditions  specific to the high-speed printer industry
               and general economic conditions.

         Additionally, because the purchase of a printing system and peripherals
is  expensive,  it may take a  significant  amount of time from the first  sales
negotiations for a customer to complete and pay for its purchase.  Historically,
certain  periods  of the year are more  profitable  than  others for the sale of
major  equipment such as our Truecolor  Systems.  We expect  fluctuations in our
revenue from  quarter to quarter to apply to the purchase of our systems.  Since
we sell few units at high  average  prices,  a delay in  either  the sale or the
receipt of the  purchase  price for only a few units  could have a  considerable
adverse effect on the results of operations for a fiscal quarter.

         A significant  portion of our operating expenses is relatively fixed in
the short term, and planned  expenditures  are based on sales  forecasts.  Sales
forecasts by our customers are  generally not binding.  Revenue  levels may fall
below expectations and disproportionately  affect operating results since only a
small portion of our expenses  vary with revenue in the short term,  which could
have a material adverse effect on our business,  financial condition and results
of operations.

         OUR DIVIDEND POLICY COULD DEPRESS OUR STOCK PRICE.

         We have never declared or paid dividends on our common stock and do not
anticipate  declaring or paying any dividends in the foreseeable future. We plan
to retain any future  earnings  to reduce our  accumulated  deficit  and finance
growth. As a result,  our dividend policy could depress the market price for our
common stock.

         WE HAVE ANTI-TAKEOVER PROVISIONS IN PLACE THAT COULD DELAY OR PREVENT A
         CHANGE IN CONTROL AND THEREFORE HURT OUR SHAREHOLDERS.

         Our Restated  Certificate of  Incorporation  contains  provisions  that
could  discourage a proxy contest or make more  difficult the  acquisition  of a
substantial  block of our common stock.  Our directors are elected on a rotating
basis  each  year.  This  makes a  change  in the  composition  of the  board of
directors  more  difficult and could make it more difficult for a third party to
acquire control of the company, even if such change of control might benefit the
shareholders.  In addition,  the board of  directors  may issue shares of common
stock and preferred  stock which, if issued,  could dilute and adversely  affect

                                       11

various  rights  of the  holders  of shares  of  common  stock.  If the board of
directors decides to issue this stock it could discourage an unsolicited attempt
to acquire us.

         We are  subject  to the  Connecticut  Business  Corporation  Act,  some
provisions of which might prevent a change of control,  even a change of control
that might benefit the company and its shareholders.

         SHARES  ELIGIBLE FOR PUBLIC SALE AFTER THIS  OFFERING  COULD  ADVERSELY
         AFFECT OUR STOCK PRICE.

         Future  sales in the  public  market of  substantial  amounts of common
stock or the  perception  that such sales may occur could cause the market price
of our  stock to drop  significantly,  even if our  business  is doing  well.  A
decline in our stock  price  could  also  impair  our  ability to raise  capital
through the offering of additional debt or equity securities.  Such future sales
of common stock includes shares:

          o    issuable  upon the  conversion  of shares  of our  series B and C
               preferred stock;

          o    issuable upon the exercise of the warrants we have granted;

          o    registered  and  sold  because  of the  exercise  of  outstanding
               registration rights; and/or

          o    issuable  upon the  exercise  of  other  outstanding  options  or
               warrants.

         As of February 8, 2000, we had 21,973,321 shares of common stock issued
and  outstanding.  If all the  outstanding  shares  of  series  C and  series  B
preferred  stock are  converted  into  shares of common  stock and if all of our
outstanding  warrants  and options  are  exercised,  we will have  approximately
41,512,567 shares of common stock issued and outstanding.

                           FORWARD-LOOKING STATEMENTS

         In this  prospectus and the documents that we incorporate by reference,
we make statements that relate to our future plans, objectives, expectations and
intentions that involve risks and uncertainties.  We have based these statements
on  our  current   expectations  and  projections  about  future  events.  These
statements may be identified by the use of words such as "expect," "anticipate,"
"intend,"  "plan,"  "believe"  and  "estimate"  and  similar  expressions.   Any
statements that refer to expectations, projections or other characterizations of
future events or circumstances are forward-looking statements within the meaning
of the Private Securities  Litigation Reform Act of 1995, and are subject to the
safe harbor created by that Act.

         Forward-looking statements necessarily involve risks and uncertainties.
Our actual results could differ  materially  from those discussed in, or implied
by, these  forward-looking  statements.  Factors that could  contribute  to such
differences  include,  but are not  limited  to,  those  discussed  in the "Risk
Factors"  section at page 2 and  elsewhere in this  prospectus.  The factors set
forth in the Risk Factors section and other  cautionary

                                       12

statements  made in this  prospectus  should  be read  and  understood  as being
applicable  to all related  forward-looking  statements  wherever they appear in
this prospectus.

         All subsequent written and oral forward-looking statements attributable
to us are expressly  qualified in their entirety by the  cautionary  statements.
You  are  cautioned  not  to  place  undue  reliance  on  these  forward-looking
statements,  which speak only as of their dates.  We undertake no obligations to
publicly update or revise any forward-looking statements, whether as a result of
new information, future events or otherwise.

                               RECENT DEVELOPMENTS

         Closing  of  private  placement  financing;  agreement  with  series  B
         preferred stockholders

         On December 7, 1999, we concluded a private equity financing of a newly
issued series of our preferred stock. In the financing,  we issued 33,589 shares
of Series C Convertible  Preferred  Stock,  receiving gross proceeds of $100 per
share or a total  of  $3,358,900.  Each  share of  series C  preferred  stock is
convertible at a fixed  conversion  rate of $0.40 divided into the $100 purchase
price. See "Selling Stockholders."

         In  connection  with the closing of our series C financing,  holders of
our series B  preferred  stock  agreed to accept  terms  similar to those of the
series C preferred  holders.  As part of the  agreement,  the series B preferred
holders agreed to accept the same fixed conversion rate as the series C holders.
In  addition,  the  series B  preferred  holders  no longer  receive a 6% annual
premium or have redemption rights.

         Increase in the number of shares of our authorized common stock

         At our annual  meeting  of  stockholders  held on Nov.  29,  1999,  the
stockholders  approved an amendment to the restated certificate of incorporation
increasing the authorized  number of shares of our common stock from  35,000,000
to 50,000,000 shares.

         Increase  in the  number  of  shares  issuable  under  our  1995  Stock
         Incentive Plan

         At our annual  meeting  of  stockholders  held on Nov.  29,  1999,  the
stockholders approved an amendment to our 1995 Stock Incentive Plan (the "Plan")
increasing  the number of shares of common  stock  issuable  under the Plan from
2,000,000 to 4,000,000 shares.

         Addition of Richard A. Hansen to our board of directors

         Richard  A.  Hansen  was  elected  by  our  board  of  directors  as an
additional  member of the board of  directors on January 31,  2000.  Mr.  Hansen
founded the investment banking firm Pennsylvania  Merchant Group ("PMG") in 1986
and has served as its Chairman and Chief Executive Officer for the past thirteen
years. Mr. Hansen also founded Radnor Venture Partners,  a venture capital fund,
which was  co-managed by PMG and Safeguard  Scientifics,  Inc.  Prior to forming
PMG, Mr. Hansen served as a Vice  President  with Kidder Peabody & Co., Inc. and
as Senior Vice  President  with Blyth

                                       13

Eastman  Dillon  which was  acquired  by Paine  Webber  Group Inc.  Prior to his
investment  banking career, he worked for Air Products & Chemicals  specializing
in merger and acquisition activity.

         Mr.  Hansen  serves on the Board of  Directors  of several  private and
public  technology-based  companies  including Ultralife Batteries and Computone
Corporation.  He received a B.S. in  Mechanical  Engineering  from the Rochester
Institute  of  Technology  and an M.S.  in  Industrial  Administration  from the
Krannert Graduate School of Business of Purdue University.

                       WHERE YOU CAN FIND MORE INFORMATION

         We are a public company and file annual,  quarterly and special reports
and other  information with the SEC. You may read and copy and documents we file
at the SEC's Public  Reference Room, 450 Fifth Street,  N.W.,  Washington,  D.C.
20549.  You may  obtain  further  information  on the  operation  of the  Public
Reference  Room by calling the SEC at  1-800-SEC-0330.  You can obtain copies of
this material from the Public  Reference  Section of the SEC,  Washington,  D.C.
20549, at prescribed  rates. Our reports,  proxy and information  statements and
other  information  are also  available to the public at the SEC's web site. The
Internet address of that site is http://www.sec.gov.

         This prospectus is only part of a registration  statement filed as Form
S-3/A on Form S 2 with the SEC  under the  Securities  Act and  therefore  omits
certain information contained in the registration  statement. We have also filed
exhibits and schedules  with the  registration  statement that are excluded from
this prospectus,  and you should refer to the applicable exhibit or schedule for
a complete  description  of any  statement  referring  to any  contract or other
document.  You may inspect a copy of the registration  statement,  including the
exhibits and  schedules,  without  charge at the SEC's public  reference room or
through its web site.

                      DOCUMENTS WE INCORPORATE BY REFERENCE

     The SEC allows us to  "incorporate  by reference"  the  information we file
with it,  which  means  that we can  disclose  important  information  to you by
referring you to other documents that contain the  information.  The information
we  incorporate  by reference is considered to be a part of this  prospectus and
automatically   updates  and  supersedes   previously  filed   information.   We
incorporate by reference the documents  listed below and all of our filings made
pursuant to the  Exchange  Act prior to the  effectiveness  of the  registration
statement:

          o    our annual  report on Form 10-K for the year ended  December  31,
               1998;

          o    our annual report on Form 10-K/A for the year ended  December 31,
               1998;

          o    our quarterly report on Form 10-Q for the quarter ended March 31,
               1999;

          o    our  quarterly  report on Form 10-Q/A for the quarter ended March
               31, 1999;

          o    our quarterly  report on Form 10-Q for the quarter ended June 30,
               1999;

                                       14

          o    our  quarterly  report on Form 10-Q/A for the quarter  ended June
               30, 1999;

          o    our quarterly report on Form 10-Q for the quarter ended September
               30, 1999; and

          o    our  current  reports  on Form 8-K filed with the SEC on July 15,
               July 26 and December 17, 1999.

         Any  statement  contained  in a document  incorporated  or deemed to be
incorporated by reference in this  prospectus  shall be deemed to be modified or
superseded  for  purposes  of this  prospectus  to the extent  that a  statement
contained  herein or in any  subsequently  filed  document  which  also is or is
deemed to be  incorporated  by reference  herein,  modifies or  supersedes  such
statement.  Any statement so modified or superseded shall not be deemed,  except
as so modified or superseded, to constitute a part of this prospectus.

         Our latest annual report to shareholders  (which includes copies of our
Form 10-K and Form 10-K/A for the year ended  December  31, 1998) and our latest
quarterly  report on Form 10-Q for the period ended  September  30, 1999 will be
delivered together with this prospectus.

         You may request  additional  copies of any of the filings  listed above
(including  any exhibits  thereto),  at no cost, by writing or telephoning us at
the following address:

                          Accent Color Sciences, Inc.,
                            800 Connecticut Boulevard
                        East Hartford, Connecticut, 06108
                       Attention: Chief Financial Officer
                            Telephone: (860) 610-4000

         Our  internet  web address is  http://www.accentcolor.com.  Information
contained on our web site or in our promotional  literature is not  incorporated
into this prospectus.

         You should rely only on the  information  contained or  incorporated by
reference in this  prospectus.  We have not  authorized  anyone  (including  any
broker  or  salesman)  to  provide  you with  information  different  from  that
contained  in  this  prospectus.  If  anyone  provides  you  with  different  or
inconsistent  information,  you should not rely on it. The selling  stockholders
are  offering to sell and seeking  offers to buy shares of our common stock only
in  jurisdictions  where offers and sales are permitted.  You should assume that
the  information  contained in this  prospectus  is accurate only as of the date
hereof.  You should not assume that this  prospectus is accurate as of any other
date.

                              SELLING STOCKHOLDERS

         This prospectus  covers  primarily  shares of our common stock issuable
upon conversion of shares of our Series C preferred  stock.  Most of the persons
listed  below  were  purchasers  of series C  preferred  stock and the shares of
common stock included in this  prospectus on their behalf are those shares which
they may acquire at any time by converting some or all of their shares of series
C  preferred  stock  into  common  stock.  There are  33,589  shares of series C
preferred stock  outstanding.  All of these shares were

                                       15

sold in a private  equity  financing  which  concluded  on December 7, 1999.  We
received gross  proceeds of $100 per share or a total of $3,358,900.  Each share
of series C preferred  stock is convertible at a fixed  conversion rate of $0.40
divided  into  the $100  purchase  price.  Therefore,  each  share  of  series C
preferred  stock is  convertible at any time into 250 shares of common stock and
all  outstanding  shares  of  series C  preferred  stock  are  convertible  into
8,397,250  shares of common  stock.  All of these  shares  are  included  in the
following table.

         The following table also includes shares being  registered  pursuant to
the exercise of "piggy-back"  registration rights which we have agreed to in the
past in connection with previous  private  placement  financings.  These include
shares  previously  issued and shares  issuable  under  outstanding  warrants to
purchase our common  stock.  Most of these shares are held by or issuable on the
exercise of warrants held by two  institutional  purchasers,  the PMG Eagle Fund
and Orbis Pension Trustees Limited,  that participated in an interim or "bridge"
financing which concluded on September 8, 1999.

         The  following  table sets forth the name of each selling  stockholder,
the  number  of  shares  of  common  stock  beneficially  owned  by the  selling
stockholder  as of February 11, 2000, the number of shares being offered by each
selling  stockholder and the number and (where  appropriate,  the percentage) of
shares held by the beneficial  owner after  completion of the offering  assuming
that all shares  offered by the  selling  stockholders  are sold.  Except as set
forth in the footnotes to the table,  none of the selling  stockholders has held
any position or office with, or otherwise had a material  relationship  with, us
in the past three  years.  All  information  is taken from or based on ownership
filings made by such persons with the Securities and Exchange Commission or upon
information  provided to us by such  person or their  agents.  Unless  otherwise
indicated,  the persons named in the table below have sole voting and investment
power with respect to all shares of common stock shown as beneficially  owned by
them.

         The selling stockholders are acting  individually,  not as a group. The
shares  which may be offered are being  registered  to permit  public  secondary
trading,  and the selling  stockholders  may offer all or part of the shares for
resale  from  time to time.  However,  the  selling  stockholders  are  under no
obligation  to sell  all or any  portion  of the  shares  nor  are  the  selling
stockholders  obligated to sell any shares  immediately  under this  prospectus.
Because the selling stockholders may sell all or part of their shares, we cannot
estimate the number of shares a selling  stockholder  will hold upon termination
of any offering made pursuant to this registration statement.

                                       16






                                          Number of Shares                           Shares Beneficially Owned
                                         Beneficially Owned        Shares to be      After the Offering (1)(2)
                                            Prior to the            Included
     Name of Selling Stockholder            Offering (1)         in the Offering        Number          Percent
     ---------------------------            ------------         ---------------        ------          -------

                                                                                               
Accrued Investments, Inc.                      100,000               62,000             38,000             *
Donald R. Allred(3)                            161,750               43,750            118,000             *
James S. Allsopp                               435,928              250,000            185,928             *
Banque Jenni & Cie, S.A.                       100,000               70,000             30,000             *
Robert A. Bedingfield                           62,500               62,500               0                0
Bexley Enterprises Limited                     636,986              500,000            136,986             *
Joseph T. Brophy(4)                            330,649              250,000             80,649             *
William P. Brown                                50,000               45,000             5,000              *
Charles Buchheit(5)                            308,334              100,000            208,334             *
Frank J. Campbell III                          172,000              140,000             32,000             *
Deed of Trust of F. J. Campbell                 70,526               60,000             10,526             *
Settlor Dtd 12/30/96, C. Crochiere,
K. Lynam & J. Meyers Co-TTEES(6)
Frank J. Campbell III and Richard A.            75,000                75,000               0                0
Hansen TTEES Trust U/W Jane D.
Campbell
Richard J. Coburn(7)                           504,303               25,000            479,303            1.3
Thomas D. Cunningham                           250,000              250,000               0                0
Robert G. Donovan                               75,698               62,500             13,698             *
Samuel Garre III                                70,000               40,000             30,000             *
Richard C. Goodwin                             150,000              150,000               0                0
E. Balkeley and Lila K. Griswold                77,619               62,500             15,119             *
PMG Eagle Fund                               3,097,500            2,687,500            410,000            1.2
Richard Hodgson(8)(9)                          198,750              100,000             98,750             *
James J. Kim                                   120,000              120,000               0                0
Richard G. Larsen                              125,000              125,000               0                0
Brian Leung Hung Tak                           636,986              500,000            136,986             *
Robert A. Leverone                              73,349               62,500             10,849             *
Luzon Investments Ltd.                       1,687,972            1,000,000            687,972            2.0
Irving L. Mazer(10)                             65,215               50,000             15,215             *
Anthony T.S. Montagu                           100,000               76,000             24,000             *
Albert G. Nickel                               138,698              125,000             13,698             *
Pacific Alliance Limited, LLC                   70,000               70,000               0                0
David Parke                                     20,000               20,000               0                0


                                       17





                                          Number of Shares                           Shares Beneficially Owned
                                         Beneficially Owned        Shares to be      After the Offering (1)(2)
                                            Prior to the            Included
     Name of Selling Stockholder            Offering (1)         in the Offering        Number          Percent
     ---------------------------            ------------         ---------------        ------          -------

                                                                                               
Orbis Pension Trustees Limited               2,687,500             2,437,500           250,000              *
David B. Payne                                  25,000                25,000               0                0
George L. Perry                                250,000               250,000               0                0
Robert J. Petras and Christine M.               25,000                25,000               0                0
Petras
Willard F. Pinney Jr.(8)(11)                   144,799                25,000           119,799              *
Leonide C. Prince                              100,000               100,000               0                0
FH Reichel Jr. TTEE FBO Marion R.              255,000               100,000           155,000              *
Reichel U/A 2/25/66
Carol A. Sharp                                 250,000               250,000               0                0
SS Family Partnership                           15,000                15,000               0                0
Elizabeth Steele(12)                           219,118                 1,500           217,618              *
Robert H. Steele(8)(13)                        219,118               112,500           106,618              *
Dr. Gershon Stern                               38,000                38,000               0                0
Sunapee Ltd. Partnership                       100,000               100,000               0                0
Kristine Szabo                                 277,396               250,000            27,396              *
Frederick C. Tecce                              30,000                30,000               0                0
Upgrade Inc.                                   100,000               100,000               0                0
Waterhouse Nominees LTD                        115,000               100,000            15,000              0
Deed of Trust of Holly E. Zug Settlor           25,000                25,000               0                0
DTD 8/5/97 Thomas V. Zug Trustee
Connecticut Innovations, Inc.                1,250,000             1,250,000               0                0
                                TOTAL:                            12,418,750


* Represents  beneficial  ownership of less than 1% of the outstanding shares of
common stock.

(1)      Beneficial ownership is determined in accordance with Rule 13d-3 of the
         Securities  Exchange  Act of 1934,  as amended.  Shares of common stock
         subject to options, warrants, rights or conversion privileges currently
         exercisable  or  exercisable  within 60 days of  February  11, 2000 are
         deemed  outstanding  for computing the percentage of the person holding
         such options,  warrants,  rights or conversion  privileges  but are not
         deemed outstanding for computing the percentage  ownership of any other
         person.

(2)      Assumes  all  shares  offered  are sold in the  offering.  The  selling
         stockholders  may or may not  sell  all or any  portion  of the  shares
         included in this registration statement in their individual discretion.

                                       18


(3)      Mr. Allred  serves as the director of R&D and new business  development
         of Accent  Color.  Includes  180,000  shares of common stock subject to
         currently  exercisable  options  granted  pursuant  to the  1995  Stock
         Incentive Plan.

(4)      Mr. Brophy serves as a director of Accent Color. Includes 40,000 shares
         of common  stock  subject  to  currently  exercisable  options  granted
         pursuant to the 1995 Stock Incentive Plan.

(5)      Mr.  Buchheit  serves as the  President,  CEO, CFO and as a director of
         Accent Color. Includes 88,334 shares of common stock subject to options
         currently exercisable or exercisable within 60 days granted pursuant to
         the 1995  Stock  Incentive  Plan and  100,000  shares of  common  stock
         subject to currently exercisable warrants.

(6)      Includes 10,526 shares of common stock subject to currently exercisable
         warrants.

(7)      Mr.  Coburn  serves as the Chairman of the Board of Directors of Accent
         Color.  Includes  43,334  shares of common  stock  subject  to  options
         currently exercisable or exercisable within 60 days granted pursuant to
         the 1995 Stock Incentive Plan.

(8)      Includes 70,000 shares of common stock subject to currently exercisable
         options granted pursuant to the 1995 Stock Incentive Plan.

(9)      Mr. Hodgson serves as a director of Accent Color. Includes 3,750 shares
         of common stock subject to currently exercisable warrants.

(10)     Includes 10,215 shares of common stock subject to currently exercisable
         warrants.

(11)     Mr.  Pinney  serves as the Secretary and as a director of Accent Color.
         Includes 30,000 shares of common stock subject to currently exercisable
         warrants granted to Murtha,  Cullina,  Richter & Pinney LLP, counsel to
         the company, of which Mr. Pinney is a partner.

(12)     Includes 1,500 shares of common stock subject to currently  exercisable
         warrants and 200,500 shares  beneficially owned by Richard Steele, Mrs.
         Steele's spouse,  as to all of which Mrs. Steele  disclaims  beneficial
         ownership.

(13)     Mr. Steele serves as a director of Accent Color. Includes 17,118 shares
         of common  stock owned by Mr.  Steele's  spouse,  Elizabeth  Steele and
         1,500 shares of common stock subject to currently  exercisable warrants
         issued to Elizabeth  Steele,  as to all of which Mr.  Steele  disclaims
         beneficial ownership.

                                 USE OF PROCEEDS

         All the shares  offered by this  prospectus  are being  offered for the
account of the selling  stockholders.  Accordingly,  all net  proceeds  from any
sales of common stock made  hereunder will go to the selling  stockholders.  The
selling  stockholders  will pay any  underwriting  discounts and commissions and
expenses incurred by the selling stockholders for brokerage,  accounting, tax or
legal services or any other  expenses  incurred by the selling  stockholders  in
disposing of the shares.  We have agreed to pay the

                                       19

expenses  of  registering  the  shares  under  the  Securities  Act,   including
registration and filing fees, blue sky expenses,  printing expenses,  accounting
fees, administrative expenses and our own counsel fees.

         We will  receive the exercise  price of any  warrants  exercised by the
selling  stockholders.  We will use any proceeds  received  from the exercise of
warrants for working capital and general corporate purposes.

                              PLAN OF DISTRIBUTION

         We  are  registering  the  shares  of  common  stock  offered  in  this
prospectus   on  behalf  of  the   selling   stockholders.   This   offering  is
self-underwritten;  neither the  selling  stockholders  nor we have  employed an
underwriter for the sale of common stock by the selling stockholders. As used in
this prospectus,  the term "selling  stockholders"  includes  donees,  pledgees,
transferees or other  successors-in-interest  selling shares  received after the
date  of  this  prospectus  from  a  selling  stockholder  as  a  gift,  pledge,
partnership distribution or other non-sale related transfer.

         The  selling  stockholders  will  act  independently  of us  in  making
decisions with respect to the timing, manner and size of each sale. As a result,
there can be no assurance that the selling  stockholders will sell any or all of
the  shares of common  stock  offered  by this  prospectus.  The sale of any the
shares  may be made at market  prices  prevailing  at the time of the  sale,  at
prices related to the  prevailing  market prices,  at negotiated  prices,  or at
fixed prices.  The selling  stockholders may offer the shares for sale by one or
more of, or a combination of, the following methods:

          o    purchases  by a  broker-dealer  as  principal  and resale by such
               broker-dealer for its own account pursuant to this prospectus;

          o    ordinary  brokerage  transactions  in  the  OTC  marketplace  and
               transactions in which the broker solicits purchasers;

          o    block trades in which the  broker-dealer  so engaged will attempt
               to sell the shares as agent but may position and resell a portion
               of the block as principal to facilitate the transaction;

          o    on one or more  exchanges on which the shares are then listed (if
               any);

          o    in privately negotiated transactions;

          o    in an underwritten offering; or

          o    by any other legally available means.

         In addition, any securities covered by this prospectus that qualify for
sale pursuant to Rule 144 under the  Securities  Act may be sold under that rule
rather than pursuant to this prospectus.

                                       20

         The  selling  stockholders  may enter into  hedging  transactions  with
broker-dealers  who may engage in short  sales of shares of common  stock in the
course of hedging the positions they assume with the selling  stockholders.  The
selling  stockholders  may also enter  into  option or other  transactions  with
broker-dealers  that require that delivery by the  broker-dealers of the shares,
which shares may be resold thereafter pursuant to this prospectus.

         To the extent required,  this prospectus may be amended or supplemented
from time to time to describe a specific plan of distribution.  We have not been
advised, as of the date of this prospectus, of any existing arrangements between
any selling stockholder and any other stockholder,  broker, dealer,  underwriter
or agent relating to the sale or distribution of the shares.

         The selling  shareholders  may sell their shares directly to purchasers
or to or through broker-dealers,  acting as agents or principals.  You should be
aware that these  broker-dealers may receive compensation for their services and
it is  possible  that  a  particular  broker-dealer's  compensation  may  exceed
customary commissions. The selling stockholders and/or any broker-dealers acting
in connection with the sale of the shares may be deemed to be underwriters under
Section  2(11)  of the  Securities  Act.  Therefore,  any  commissions  or other
compensation  received by them and any profits realized by them on the resale of
the  shares as  principals  may be deemed  underwriting  compensation  under the
securities laws.  Neither we nor any selling  stockholder can presently estimate
the amount of the compensation.

         In order to comply  with the  securities  laws of  certain  states,  if
applicable,  the  shares  must  be  sold  in  such  jurisdictions  only  through
registered or licensed  brokers or dealers.  In addition,  in certain states the
shares may not be sold unless they have been registered or qualified for sale in
the applicable  state or an exemption  from the  registration  or  qualification
requirement is available and is complied with.

         Each  selling  stockholder  and any other  persons  participating  in a
distribution  of  securities  will be subject to  applicable  provisions  of the
Exchange Act and the rules and regulations  thereunder,  including Regulation M,
which may restrict certain activities of selling  stockholders and other persons
participating  in a  distribution  of  securities  and limit the timing of their
purchases  and sales of  securities.  Furthermore,  under  Regulation M, persons
engaged in a  distribution  of securities  are  prohibited  from  simultaneously
engaging  in market  making and certain  other  activities  with  respect to the
securities  for  a  specified  period  of  time  before  the  beginning  of  the
distributions  subject  to  specified  exceptions  or  exemptions.  All  of  the
foregoing may affect the  marketability  of the securities  offered  pursuant to
this registration statement.

         We have agreed to indemnify the selling  stockholders and each of their
officers,  directors,  members, employees,  partners, agents and each person who
controls  any of the selling  stockholders  against  certain  expenses,  claims,
losses,  damages  and  liabilities  (or  action,  proceeding  or  inquiry by any
regulatory or  self-regulatory  organization in respect  thereof).  We have also
agreed with the selling stockholders to keep the registration statement of which
this prospectus  constitutes a part effective until the earlier of (1) such time
as all of the shares covered by this  prospectus  have been disposed of pursuant
to and in  accordance  with  the  registration  statement  or  (2)  the  selling
stockholders  become

                                       21

eligible to resell the shares covered by this prospectus pursuant to Rule 144(k)
under the Securities Act.

                          DESCRIPTION OF OUR SECURITIES

         We are authorized to issue  50,000,000  shares of common stock,  no par
value, and 500,000 shares of preferred stock, no par value. Set forth below is a
brief  description  of  our  capital  stock,   including  summaries  of  certain
provisions in the Company's  restated  certificate of incorporation,  its Bylaws
and the Connecticut Business  Corporations Act (the "Act") and other laws of the
State of  Connecticut  and are qualified in their  entirety by reference to such
documents,  copies of which  have been  filed as  exhibits  to the  registration
statement.

         Common Stock

         Our common  stock is traded on the OTC  Bulletin  Board of the National
Association  of Securities  Dealers,  Inc. under the symbol "ACLR." The transfer
agent and  registrar  of our common  stock is  American  Stock  Transfer & Trust
Company.

         As of February 8, 2000,  there were  21,973,321  shares of common stock
issued and outstanding. In addition, there were

          o    8,397,250  shares  of  common  stock  reserved  for  issuance  on
               conversion of shares of series C preferred stock;

          o    3,640,899 shares reserved for issuance on conversion of shares of
               series B preferred stock;

          o    4,268,347  shares  reserved for issuance upon exercise of certain
               outstanding warrants; and

          o    3,232,750  shares  reserved for issuance  upon  exercise of stock
               options granted under our 1995 Stock Incentive Plan.

         Common  stockholders  are entitled to receive ratably such dividends as
may be  declared  on the  common  stock by our board of  directors  out of funds
legally available therefor,  subject to the prior rights of holders of preferred
stock.  Holders of common  stock are entitled to one vote for each share held of
record with respect to the election of directors and other matters submitted for
a vote of  shareholders  and are not entitled to cumulative  voting.  Holders of
common stock vote  together  with  holders of preferred  stock as a single class
with respect to the election of directors and other matters.

         Upon the  liquidation,  dissolution  or winding up of the company,  the
holders of common stock are entitled to receive ratably the Company's net assets
available  after the payment of all debts and other  liabilities  and subject to
the  prior  rights  of the  outstanding  shares  of our  series  B and  series C
preferred  stock.  Holders  of common  stock have no  preemptive,  subscription,
redemption or conversion rights.

                                       22


         Preferred Stock

         The rights,  preferences and privileges of shareholders of common stock
are subject to the prior  rights of the  outstanding  shares of our series B and
series C preferred stock.

         Series A preferred stock

         Pursuant   to   article   fourth  of  our   restated   certificate   of
incorporation, our board or directors has designated a series of preferred stock
entitled series A convertible  preferred stock. All previously  issued shares of
series A preferred  stock have been converted into common stock and there are no
shares of such series outstanding.

         Series B preferred stock

         In 1997, our board of directors  designated a series of 4,500 shares of
our  previously  authorized  preferred  stock to be  designated  as the Series B
Convertible  Preferred Stock. On January 13, 1998, we issued 4,500 shares of the
series B stock at a price of $1,000 per share.  The series B preferred  stock is
convertible  into such  number of shares  of common  stock as is  determined  by
dividing  $1,113.43  (being  the face  value of $1,000 of each share of series B
stock plus a 6% premium  from the date of  issuance  to Nov.  30, 1999 when such
premiums ceased to accrue) by a fixed conversion rate of $0.40. Therefore,  each
share of series B stock is convertible into approximately 2,784 shares of common
stock.

         The holders of the series B  preferred  stock  carry  voting  rights as
provided in the our  restated  certificate  of  incorporation  and as  otherwise
provided by the Act.  Holders of series B  preferred  stock vote  together  with
holders  of common  stock and  holders of series C  preferred  stock as a single
class with respect to the election of directors and other  matters.  Each holder
of series B preferred  stock is  entitled to as many votes with  respect to each
share of series B  preferred  stock held on the record date for such vote as the
number of shares of common stock into which a share of series B preferred  stock
is then convertible.

         The  series B  preferred  stock does not bear  dividends.  The series B
preferred  stock  ranks  senior to our  common  stock and equal to our  series C
preferred  stock with respect to  liquidation.  Each share of series B preferred
stock is  entitled  to receive $ 1,113.43  upon  liquidation.  As of February 8,
2000,  there were 1,308 shares of series B preferred stock  outstanding all held
by one institutional investor.

         Series C preferred stock

         On November  29, 1999,  the board of  directors  designated a series of
50,000 shares of our previously  authorized  preferred  stock,  no par value per
share, to be designated as the Series C Convertible Preferred Stock. On December
7, 1999, we concluded the issuance of 33,589 shares of series C preferred  stock
at a  purchase  price  of $100  per  share.  The  series  C  preferred  stock is
convertible  at any time into shares of our common  stock at a fixed  conversion
price of $0.40 per share.

                                       23


         The holders of the series C  preferred  stock  carry  voting  rights as
provided in the our  restated  certificate  of  incorporation  and as  otherwise
provided by the Act.  Holders of series C  preferred  stock vote  together  with
holders  of common  stock and  holders of series B  preferred  stock as a single
class with respect to the election of directors and other  matters.  Each holder
of series C preferred  stock is  entitled to as many votes with  respect to each
share of series C  preferred  stock held on the record date for such vote as the
number of shares of common stock into which a share of series C preferred  stock
is then convertible.

         Series C holders are entitled to receive  noncumulative  cash dividends
as  declared by the board of  directors,  except  that no such  dividend  can be
declared  unless  an  equivalent,  ratable  dividend  is  also  declared  on the
outstanding  shares of series B preferred  stock. In addition,  series C holders
are  entitled to receive  cumulative  dividends  at a rate of 8% per year of the
initial  purchase  price of $100 per  share but only  upon the  occurrence  of a
Liquidation Event, provided that any such dividend is coupled with an equivalent
ratable dividend to the holders of the series B stock. A "Liquidation  Event" is
defined  to  include  a merger  (except a merger  in which  Accent  Color is the
surviving   entity),   consolidation,   dissolution,   winding  up  or  sale  of
substantially  all of the assets of the company,  unless the holders of at least
75% of the  series B and series C stock  determine  that any such event is not a
Liquidation Event.

         In the  event  of  any  voluntary  or  involuntary  liquidation  of the
company,  the  series C holders  rank  equal to the series B holders in right of
payment  and senior to the common  stock.  As of  February  8, 2000,  there were
33,589 shares of series C preferred stock outstanding.

         Certain  provisions of Connecticut law and our restated  certificate of
incorporation

         Our restated  certificate of  incorporation  contains  provisions  that
could  discourage a proxy contest or make more  difficult the  acquisition  of a
substantial block of our common stock. The restated certificate of incorporation
provides  for a  classified  board of  directors,  and  members  of the board of
directors may be removed only upon the  affirmative  vote of holders of at least
two-thirds  of the  shares of our  capital  stock  issued  and  outstanding  and
entitled to vote.  In addition,  since the board of directors is  authorized  to
issue shares of common stock and preferred  stock any such issuance could dilute
and  adversely  affect  various  rights of the holders of shares of common stock
and, in addition,  could be used to discourage an unsolicited attempt to acquire
control of the company.

         As  a  Connecticut  corporation,  we  are  subject  to  the  Act,  some
provisions  of which  prohibit  a  publicly-held  Connecticut  corporation  from
engaging  in  a  "business  combination"   (including  the  issuance  of  equity
securities  which  have an  aggregate  market  value of 5% or more of the  total
market value of our  outstanding  shares) with an "interested  shareholder"  (as
defined  in  the  Act)  for a  period  of  five  years  from  the  date  of  the
shareholder's  purchase of stock  unless  approved in a prescribed  manner.  The
application  of this  section  could  prevent  a change of  control.  Generally,
approval  is  required  by the  board  of  directors  and by a  majority  of our
non-employee  directors and by 80% of our  outstanding  shares and two-thirds of
the voting power of shares other than

                                       24

shares held by the interested shareholder.  There can be no assurance that these
provisions  will not prevent us from entering into a business  combination  that
otherwise would be beneficial to us.

                                  LEGAL MATTERS

         Counsel for Accent Color,  Murtha,  Cullina,  Richter and Pinney,  LLP,
CityPlace I, 185 Asylum Street, Hartford,  Connecticut 06103-3469,  has rendered
an opinion to the effect that the common  stock  offered for resale  pursuant to
this  registration  statement  is  duly  and  validly  issued,  fully  paid  and
non-assessable.  Murtha,  Cullina,  Richter  and  Pinney  LLP owns a warrant  to
acquire up to 30,000  shares of our common  stock at an exercise  price of $1.19
per share.

         Willard F.  Pinney,  Jr., a partner in  Murtha,  Cullina,  Richter  and
Pinney LLP,  is a  stockholder  of Accent  Color.  Mr.  Pinney has served as our
Corporate Secretary since 1993 and has served as a director since 1996.

                                     EXPERTS

         The financial  statements  incorporated in this prospectus by reference
to Accent  Color's  Annual Report on Form 10-K/A for the year ended December 31,
1998   have   been   so    incorporated   in   reliance   on   the   report   of
PricewaterhouseCoopers  LLP, independent accountants,  given on the authority of
PricewaterhouseCoopers LLP as experts in auditing and accounting.

                                       25


                                     PART II

                     INFORMATION NOT REQUIRED IN PROSPECTUS

ITEM 14.  OTHER EXPENSES OF ISSUANCE AND DISTRIBUTION

         The following  table sets forth our estimates of the expenses  incurred
in connection with the sale of common stock being registered,  all of which will
be paid by us.

SEC registration fee                                             $2,926
Legal fees and expenses                                         $15,000
Accounting fees and expenses                                     $7,500
Miscellaneous fees and expenses                                  $2,500
                                                TOTAL:          $27,926

         The  selling  stockholders  will  pay any  underwriting  discounts  and
commissions  and expenses  incurred by the selling  stockholders  for brokerage,
accounting,  tax or legal services or any other expenses incurred by the selling
stockholders  in  disposing  of the  shares  of  common  stock  covered  by this
prospectus.

ITEM 15.  INDEMNIFICATION OF DIRECTORS AND OFFICERS

         We are a Connecticut corporation. Sections 33-770 through 33-778 of the
Connecticut  Business  Corporations Act ("Act") provide that,  unless limited by
its certificate of incorporation,  a corporation shall indemnify any director or
officer  of the  corporation  against  reasonable  expenses  incurred  by him in
connection  with  any  action,  suit or  proceeding  in  which  he is made or is
threatened  to be made a party by reason of having been a director or officer of
the  corporation  if he was wholly  successful  in the action,  on the merits or
otherwise.

         In addition,  these  sections of the Act permit a corporation by action
of its  board  of  directors  to  indemnify  an  individual  made a  party  to a
proceeding because he was a director or officer of the corporation if:

          o    he or she conducted himself in good faith, and

          o    he or she  reasonably  believed (1) in the case of conduct in his
               official  capacity with the  corporation,  his conduct was in the
               best  interests  of the  corporation  and (2) in all other cases,
               that his conduct  was at least not opposed to the best  interests
               of the corporation and

          o    in  the  case  of  any  criminal  proceeding,  he or  she  had no
               reasonable cause to believe his or her conduct was unlawful.

          Section  33-771 also provides  that a corporation  may not indemnify a
director or officer (1) in  connection  with a proceeding  by or in the right of
the  corporation  in which

                                       26

the director or officer was held liable to the  corporation or (2) in connection
with any other proceeding  charging improper personal benefit to the director or
officer in which he was adjudged  liable on the basis that personal  benefit was
improperly  received by him, whether or not the action involved was taken in his
official capacity.

         Our restated certificate of incorporation limits the personal liability
of a director to the company or its shareholders for monetary damages for breach
of duty as a director, to an amount equal to the amount of compensation received
by the director  for serving  during the  calendar  year in which the  violation
occurred.  This  limit  on  liability  is  subject  to a number  of  exceptions,
including violations involving a knowing and culpable violation of law, a breach
of duty which enables a director or an associate to receive an improper personal
gain,  conduct  showing a lack of good faith and conscious  disregard of duty to
the company,  a sustained and unexcused pattern of inattention,  or the approval
of an illegal distribution of assets of the company to its shareholders.

         For purposes of determining  the receipt  improper  personal  gains, an
"associate" is defined as (1) any corporation or organization of which an Accent
Color  director  is an officer or partner or is,  directly  or  indirectly,  the
beneficial  owner of ten percent or more of any class of voting  stock,  (2) any
trust or other  estate in which a director  has at least ten percent  beneficial
interest or as to which a director  serves as trustee or in a similar  fiduciary
capacity  and (3) any  relative or spouse of a director,  or any relative of the
spouse who has the same name as the Accent Color director.

         In addition,  we also maintain a directors' and officers' insurance and
reimbursement policy.

Item 16.  EXHIBITS

         (a)      Exhibits:

      Exhibit No.                       Exhibit
      ---------                         -------

         3.1      Restated  Certificate  of  Incorporation  of the  Company,  as
                  amended (filed herewith).

         3.2      Certificate   of   Amendment   to  Restated   Certificate   of
                  Incorporation, dated Nov. 29, 1999 (filed herewith).

         3.3      Certificate of Designations,  Preferences and Rights of Series
                  B  Convertible  Preferred  Stock  (filed  herewith  as part of
                  Exhibit 3.1).

         3.4      Certificate of Designations,  Preferences and Rights of Series
                  C  Convertible  Preferred  Stock,  dated Nov.  29, 1999 (filed
                  herewith).

         3.5      Bylaws of the Company, as amended December 29, 1996(1)

         4.1      Letter   agreement   with  holders  of  Series  B  Convertible
                  Preferred  Stock  modifying  rights to conform  with  Series C
                  Convertible Preferred Stock

                                       27


                  (filed herewith).

         5        Opinion of Murtha,  Cullina,  Richter and  Pinney,  LLP (filed
                  herewith)

         10.1     Product Development and Distribution  Agreement dated February
                  16, 1996 between the Company and Xerox Corporation (2).

         10.2     Letter of Understanding dated July 2, 1996 between the Company
                  and Xerox Corporation  supplementing  the Product  Development
                  and Distribution Agreement (2).

         10.3     Amendment to Product  Development and  Distribution  Agreement
                  between the Company and Xerox  Corporation  dated February 29,
                  1996 (2).

         10.4     Loan Agreement Promissory Note dated February 29, 1996 between
                  the Company and Xerox Corporation (2).

         10.5     Product  Purchase  Agreement  dated April 16, 1996 between the
                  Company and International Business Machines Corporation (2).

         10.6     Letter  Agreement  supplementing  Product  Purchase  Agreement
                  between  the  Company  and  International   Business  Machines
                  Corporation dated February 23, 1996 (2).

         10.7     OEM Supply Agreement dated January 8, 1996 between the Company
                  and Spectra, Inc. (2).

         10.8     Amendment  No. 1 to the OEM  Supply  Agreement  dated July 12,
                  1996 between the Company and Spectra, Inc. (2).

         10.9     Lease  Agreement  dated  February 16, 1996 between the Company
                  and John Hancock Mutual Life Insurance company (2).

         10.10    Memorandum of Understanding dated October 10, 1996 between the
                  Company and Oce van der Grinten, N.V. (2).

         10.11    Accent Color  Sciences,  Inc. 1995 Stock  Incentive  Plan., as
                  amended through Nov. 29, 1999 (filed herewith).

         10.12    Employment  Agreement  dated  December  14,  1993  between the
                  Company and Norman L. Milliard (2).

         10.13    Amendment  No. 1 to Employment  Agreement  between the Company
                  and Norman L. Milliard dated as of January 1, 1995 (2).

         10.14    Employment  Agreement  dated  December  14,  1993  between the
                  Company and Richard J. Coburn (2).

                                       28


         10.15    Consulting  Agreement dated August 2, 1994 between the Company
                  and Peter Teufel (2).

         10.16    Consulting Agreement dated May 3, 1996 between the Company and
                  Raymond N. Smith. (2).

         10.17    Consulting  Agreement Dated August 2, 1994 between the Company
                  and Klaus Werding (2).

         10.18    Letter  Agreement  dated February 28, 1996 between the Company
                  and Pennsylvania Merchant Group Ltd. (2).

         10.19    Letter  Agreement  dated May 6, 1996  between  the Company and
                  Pennsylvania Merchant Group Ltd. (2).

         10.20    Termination  Agreement  dated  August  20,  1996  between  the
                  Company and Pennsylvania Merchant Group Ltd. (2).

         10.21    Termination Agreement dated March 29, 1996 between the Company
                  and Knickerbocker Securities, Inc. (2).

         10.22    Form of  nondisclosure  agreement  between the Company and its
                  employees (2).

         10.23    Form of  Registration  Rights  Agreement  Relating  to sale of
                  Preferred Stock of the Company (2).

         10.24    Form of  Registration  Rights  Agreement  Relating  to sale of
                  Series III Debentures of the Company (2).

         10.25    Form of  Registration  Rights  Agreement  Relating to warrants
                  issued in connection with Series III Debentures of the Company
                  (2).

         10.26    Form of  Registration  Rights  Agreement  Relating to Warrants
                  issued in connection  with Series IV Debentures of the Company
                  (2).

         10.27    Form of  Registration  Rights  Agreement  Relating  to sale of
                  Common Stock of the Company (2).

         10.28    Registration  Rights Agreement  Relating to Warrants issued by
                  the Company to Xerox Corporation (2).

         10.29    Form of  Registration  Rights  Agreement  Relating to Warrants
                  issued pursuant to sale of Interim Notes (2).

         10.30    Form of Securities Purchase Agreement dated as of Jan. 9, 1998
                  (3).

         10.31    Form of Warrant  issued in  connection  with the 1998  Private
                  Placement (3).

                                       29


         10.32    Form of Registration Rights Agreement dated as of Jan. 9, 1998
                  (3).

         10.33    Employment  Agreement  dated April 15, 1998 between Charles E.
                  Buchheit and the Company (4).

         10.34    Loan Agreement between the Company and International  Business
                  Machines Corporation (5).

         10.35    Promissory Note between the Company and International Business
                  Machines Corporation (5).

         10.36    Security  Agreement  between  the  Company  and  International
                  Business Machines Corporation (5).

         10.37    Form of Securities Purchase Agreement dated as of November 30,
                  1999 (6).

         10.38    Form of Warrant Agreement dated as of November 30, 1999 (6).

         10.39    Form of Registration Rights Agreement dated as of November 30,
                  1999 (6).

         23.1     Consent of Murtha,  Cullina,  Richter and  Pinney,  LLP (filed
                  herewith in the opinion set forth as Exhibit 5).

         23.2     Consent of PricewaterhouseCoopers LLP (filed herewith).

         24       Power  of  attorney   pursuant  to  which  this   registration
                  statement is signed by certain directors (6).


(1) incorporated by reference from Accent Color's registration statement on Form
S-3 (file no. 333-43467) filed December 30, 1997, as amended.

(2) incorporated by reference from Accent Color's  registration  statement (file
no. 333-14043) on Form S-1 filed on Oct. 15, 1996, as amended.

(3) incorporated by reference from Accent Color's  registration  statement (file
no. 333-45321) on Form S-3 filed on Jan. 30, 1998, as amended.

(4) incorporated by reference from Accent Color's  quarterly report on Form 10-Q
for the quarter ended June 30, 1998.

(5) incorporated by reference from Accent Color's  quarterly report on Form 10-Q
for the quarter ended Sep. 30, 1998.

(6) incorporated by reference from Accent Color's  registration  statement (file
no. 333-30130) on Form S-3 filed on Feb. 11, 2000.


                                       30


Item 17.  UNDERTAKINGS

         (a)      The undersigned registrant undertakes:

                  (1) To file,  during any  period in which  offers or sales are
         being made, a post-effective amendment to this Registration Statement:

                           (i)  To  include  any prospectus  required by Section
                  10(a)(3)   of  the  Securities  Act  of 1933,  as amended (the
                  "Securities Act");

                           (ii) To reflect in the prospectus any facts or events
                  arising  after  the  effective   date  of  this   Registration
                  Statement  (or  the  most  recent   post-effective   amendment
                  thereof) which, individually or in the aggregate,  represent a
                  fundamental  change  in the  information  set  forth  in  this
                  Registration  Statement.  Notwithstanding  the foregoing,  any
                  increase or decrease in the volume of  securities  offered (if
                  the total dollar value of securities  offered would not exceed
                  that which was  registered)  and any deviation from the low or
                  high  end of  the  estimated  maximum  offering  range  may be
                  reflected in the form of prospectus  filed with the Commission
                  pursuant to Rule 424(b) if, in the  aggregate,  the changes in
                  volume and price  represent no more than 20 percent  change in
                  the  maximum  aggregate   offering  price  set  forth  in  the
                  "Calculation  of  Registration  Fee"  table  in the  effective
                  Registration Statement; and

                           (iii)  To  include  any  material   information  with
                  respect to the plan of distribution  not previously  disclosed
                  in this Registration  Statement or any material change to such
                  information in this Registration Statement;

                   (2) That, for the purposes of determining any liability under
         the Securities Act, each post-effective  amendment that contains a form
         of  prospectus  shall  be  deemed  to be a new  registration  statement
         relating to the securities  offered  therein,  and the offering of such
         securities  at the time  shall be  deemed to be the  initial  bona fide
         offering thereof.

                   (3) To remove from  registration by means of a post-effective
         amendment any of the securities being registered which remain unsold at
         the termination of the offering.

         (b)  Insofar  as  indemnification  for  liabilities  arising  under the
Securities Act may be permitted to directors,  officers and controlling  persons
of the  registrant  pursuant to the  foregoing  provisions,  or  otherwise,  the
registrant  has been advised that in the opinion of the  Securities and Exchange
Commission  the  indemnification  is against  public  policy as expressed in the
Securities Act and is, therefore,  unenforceable. If a claim for indemnification
against these liabilities  (other than the payment by the registrant of expenses
incurred or paid by a director,  officer or controlling person of the registrant
in the  successful  defense of any action,  suit or proceeding) is asserted by a
director,  officer or controlling person in connection with the securities being
registered, the registrant will, unless in the opinion of its counsel the matter
has been  settled by  controlling  precedent,  submit to a court of  appropriate
jurisdiction the question whether indemnification by it is

                                       31

against public policy as expressed in the Securities Act and will be governed by
the final adjudication of the issue.



                                       32




                                   SIGNATURES

         Pursuant  to the  requirements  of the  Securities  Act  of  1933,  the
registrant certifies that it has reasonable grounds to believe that it meets all
of the  requirements  for filing on Form  S-3/A on Form S-2 and has duly  caused
this registration  statement to be signed on its behalf by the undersigned,  who
is duly authorized,  in the City of East Hartford,  State of Connecticut on this
24th day of February 2000.

                                        ACCENT COLOR SCIENCES, INC.


                                                        /s/
                                        ----------------------------------
                                        By:  Charles E. Buchheit
                                        Title: President, Chief Executive
                                               Officer and Director

         Pursuant  to the  requirements  of the  Securities  Act  of  1933,  the
following persons have signed this registration  statement in the capacities and
on the dates indicated.





            Signature                                 Title                              Date
            ---------                                 -----                              ----
                                                                                

By:         /s/                            President, Chief Executive            February 24, 2000
   ------------------------                Officer and Chief Financial
Name:  Charles E. Buchheit                           Officer

By:        /s/                              Vice Chairman and Chief              February 24, 2000
   ------------------------                     Technology Officer
Name:  Norman L. Milliard

By:        /s/                                Chairman of the Board of           February 24, 2000
   ------------------------                         Directors
Name: Richard J. Coburn

By:        /s/             *                         Director                    February 24, 2000
   ------------------------
Name: Joseph T. Brophy


By:       /s/              *                         Director                    February 24, 2000
   ------------------------
Name: Richard Hodgson


                                       33


By:       /s/              *                  Secretary and Director             February 24, 2000
   ------------------------
Name: Willard F. Pinney, Jr.


By:       /s/              *                         Director                    February 24, 2000
   ------------------------
Name: Robert H. Steele


* Signature by Charles E. Buchheit, attorney-in-fact

                                       34



         EXHIBIT INDEX

      Exhibit No.               Exhibit
      ---------                 -------

         3.1      Restated  Certificate  of  Incorporation  of the  Company,  as
                  amended (filed herewith).

         3.2      Certificate   of   Amendment   to  Restated   Certificate   of
                  Incorporation, dated Nov. 29, 1999 (filed herewith).

         3.3      Certificate of Designations,  Preferences and Rights of Series
                  B  Convertible  Preferred  Stock  (filed  herewith  as part of
                  Exhibit 3.1).

         3.4      Certificate of Designations,  Preferences and Rights of Series
                  C  Convertible  Preferred  Stock,  dated Nov.  29, 1999 (filed
                  herewith).

         3.5      Bylaws of the Company, as amended December 29, 1996(1)

         4.1      Letter   agreement   with  holders  of  Series  B  Convertible
                  Preferred  Stock  modifying  rights to conform  with  Series C
                  Convertible Preferred Stock (filed herewith).

         5        Opinion of Murtha,  Cullina,  Richter and  Pinney,  LLP (filed
                  herewith)

         10.1     Product Development and Distribution  Agreement dated February
                  16, 1996 between the Company and Xerox Corporation (2).

         10.2     Letter of Understanding dated July 2, 1996 between the Company
                  and Xerox Corporation  supplementing  the Product  Development
                  and Distribution Agreement (2).

         10.3     Amendment to Product  Development and  Distribution  Agreement
                  between the Company and Xerox  Corporation  dated February 29,
                  1996 (2).

         10.4     Loan Agreement Promissory Note dated February 29, 1996 between
                  the Company and Xerox Corporation (2).

         10.5     Product  Purchase  Agreement  dated April 16, 1996 between the
                  Company and International Business Machines Corporation (2).

         10.6     Letter  Agreement  supplementing  Product  Purchase  Agreement
                  between  the  Company  and  International   Business  Machines
                  Corporation dated February 23, 1996 (2).

         10.7     OEM Supply Agreement dated January 8, 1996 between the Company
                  and Spectra, Inc. (2).

                                       35

         10.8     Amendment  No. 1 to the OEM  Supply  Agreement  dated July 12,
                  1996 between the Company and Spectra, Inc. (2).

         10.9     Lease  Agreement  dated  February 16, 1996 between the Company
                  and John Hancock Mutual Life Insurance company (2).

         10.10    Memorandum of Understanding dated October 10, 1996 between the
                  Company and Oce van der Grinten, N.V. (2).

         10.11    Accent Color  Sciences,  Inc. 1995 Stock  Incentive  Plan., as
                  amended through Nov. 29, 1999 (filed herewith).

         10.12    Employment  Agreement  dated  December  14,  1993  between the
                  Company and Norman L. Milliard (2).

         10.13    Amendment  No. 1 to Employment  Agreement  between the Company
                  and Norman L. Milliard dated as of January 1, 1995 (2).

         10.14    Employment  Agreement  dated  December  14,  1993  between the
                  Company and Richard J. Coburn (2).

         10.15    Consulting  Agreement dated August 2, 1994 between the Company
                  and Peter Teufel (2).

         10.16    Consulting Agreement dated May 3, 1996 between the Company and
                  Raymond N. Smith. (2).

         10.17    Consulting  Agreement Dated August 2, 1994 between the Company
                  and Klaus Werding (2).

         10.18    Letter  Agreement  dated February 28, 1996 between the Company
                  and Pennsylvania Merchant Group Ltd. (2).

         10.19    Letter  Agreement  dated May 6, 1996  between  the Company and
                  Pennsylvania Merchant Group Ltd. (2).

         10.20    Termination  Agreement  dated  August  20,  1996  between  the
                  Company and Pennsylvania Merchant Group Ltd. (2).

         10.21    Termination Agreement dated March 29, 1996 between the Company
                  and Knickerbocker Securities, Inc. (2).

         10.22    Form of  nondisclosure  agreement  between the Company and its
                  employees (2).

         10.23    Form of  Registration  Rights  Agreement  Relating  to sale of
                  Preferred Stock of the Company (2).

         10.24    Form of  Registration  Rights  Agreement  Relating  to sale of
                  Series III

                                       36


                  Debentures of the Company (2).

         10.25    Form of  Registration  Rights  Agreement  Relating to warrants
                  issued in connection with Series III Debentures of the Company
                  (2).

         10.26    Form of  Registration  Rights  Agreement  Relating to Warrants
                  issued in connection  with Series IV Debentures of the Company
                  (2).

         10.27    Form of  Registration  Rights  Agreement  Relating  to sale of
                  Common Stock of the Company (2).

         10.28    Registration  Rights Agreement  Relating to Warrants issued by
                  the Company to Xerox Corporation (2).

         10.29    Form of  Registration  Rights  Agreement  Relating to Warrants
                  issued pursuant to sale of Interim Notes (2).

         10.30    Form of Securities Purchase Agreement dated as of Jan. 9, 1998
                  (3).

         10.31    Form of Warrant  issued in  connection  with the 1998  Private
                  Placement (3).

         10.32    Form of Registration Rights Agreement dated as of Jan. 9, 1998
                  (3).

         10.33    Employment  Agreement  dated April 15, 1998 between Charles E.
                  Buchheit and the Company (4).

         10.34    Loan Agreement between the Company and International  Business
                  Machines Corporation (5).

         10.35    Promissory Note between the Company and International Business
                  Machines Corporation (5).

         10.36    Security  Agreement  between  the  Company  and  International
                  Business Machines Corporation (5).

         10.37    Form of Securities Purchase Agreement dated as of November 30,
                  1999 (6).

         10.38    Form of Warrant Agreement dated as of November 30, 1999 (6).

         10.39    Form of Registration Rights Agreement dated as of November 30,
                  1999 (6).

         23.1     Consent of Murtha,  Cullina,  Richter and  Pinney,  LLP (filed
                  herewith in the opinion set forth as Exhibit 5).

         23.2     Consent of PricewaterhouseCoopers LLP (filed herewith).

                                       37


         24       Power  of  attorney   pursuant  to  which  this   registration
                  statement is signed by certain directors (6).


(1) incorporated by reference from Accent Color's registration statement on Form
S-3 (file no. 333-43467) filed December 30, 1997, as amended.

(2) incorporated by reference from Accent Color's  registration  statement (file
no. 333-14043) on Form S-1 filed on Oct. 15, 1996, as amended.

(3) incorporated by reference from Accent Color's  registration  statement (file
no. 333-45321) on Form S-3 filed on Jan. 30, 1998, as amended.

(4) incorporated by reference from Accent Color's  quarterly report on Form 10-Q
for the quarter ended June 30, 1998.

(5) incorporated by reference from Accent Color's  quarterly report on Form 10-Q
for the quarter ended Sep. 30, 1998.

(6) incorporated by reference from Accent Color's  registration  statement (file
no. 333-30130) on Form S-3 filed on Feb. 11, 2000.


                                       38