Exhibit 23 Consent of Independent Auditors We consent to the incorporation by reference in the Registration Statements (Forms S-3, No. 333-15533, 33-58736, 33-60229, 33-78760, 33-72170, 33-68542 and Forms S-8 No. 33-45348, 33-75466, 33-88826 and 333-87153) of Enzo Biochem, Inc. and in the related Prospectus of our report dated October 16, 2000, with respect to the consolidated financial statements and schedule of Enzo Biochem, Inc. included in this Annual Report (Form 10-K) for the fiscal year ended July 31, 2000. /s/ Ernst & Young LLP Melville, New York October 27, 2000