Exhibit 32.1


                        CERTIFICATION OF PERIODIC REPORT


I, John G. Baust, Chief Executive Officer and Chief Financial Officer of Biolife
Solutions, Inc. (the "Company"), certify, pursuant to Section 906 of the
Sarbanes-Oxley Act of 2002, 18 U.S.C. Section 1350, that:

         1.    the Quarterly Report on Form 10-QSB of the Company for the
               quarterly period ended June 30, 2004 (the "Report") fully
               complies with the requirements of Section 13(a) or 15(d) of the
               Securities Exchange Act of 1934 (15 U.S.C. 78m or 78o(d)); and

         2.    the information contained in the Report fairly presents, in all
               material respects, the financial condition and results of
               operations of the Company.

Dated:   August 11, 2004


/s/ John G. Baust
- ----------------------------
John G. Baust, PhD
Chief Executive Officer and
Chief Financial Officer


A signed original of this written statement required by Section 906 of the
Sarbanes-Oxley Act of 2002 has been provided to the Company and will be retained
by the Company and furnished to the Securities and Exchange Commission or its
staff upon request.


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