Exhibit 31.1


                                 CERTIFICATION

         I, John G. Baust, Chief Executive Officer and Chief Financial Officer
of BioLife Solutions, Inc. (the "Registrant"), certify that:

         1.       I have reviewed this quarterly report on Form 10-QSB of the
Registrant;

         2.       Based on my knowledge, this report does not contain any untrue
statement of a material fact or omit to state a material fact necessary to make
the statements made, in light of the circumstances under which such statements
were made, not misleading with respect to the period covered by this report;

         3.       Based on my knowledge, the financial statements, and other
financial information included in this report, fairly present in all material
respects the financial condition, results of operations and cash flows of the
Registrant as of, and for, the periods presented in this report;

         4.       I am responsible for establishing and maintaining disclosure
controls and procedures (as defined in Exchange Act Rules 13a-15(e) and
15d-15(e)) for the Registrant and I have:

                  a)       designed such disclosure controls and procedures, or
         caused such disclosure controls and procedures to be designed under my
         supervision, to ensure that material information relating to the
         Registrant, including its consolidated subsidiaries, is made known to
         me by others within those entities, particularly during the period in
         which this report is being prepared; and

                  b)       evaluated the effectiveness of the Registrant's
         disclosure controls and procedures and presented in this report my
         conclusions about the effectiveness of the disclosure controls and
         procedures, as of the end of the period covered by this report based on
         such evaluation.

Dated:   August 15, 2005


/s/ John G. Baust
- ---------------------------
John G. Baust, PhD
Chief Executive Officer
and Chief Financial Officer