POWER OF ATTORNEY
September 24, 2015

	The undersigned hereby constitutes and appoints each of Thomas R. Staab II and
Alane P. Barnes, the Senior Vice President, Chief Financial Officer & Treasurer
and the Vice President, General Counsel & Corporate
Secretary, respectively, of BioCryst Pharmaceuticals, Inc. (the ?Company?),
signing singly and not jointly, with full power of substitution, as the
undersigned's true and lawful attorney-in-fact to:

(1) prepare, execute in the undersigned's name and on the undersigned's
behalf, and submit to the U.S. Securities and Exchange Commission (the ?SEC?) a
Form ID, including amendments thereto (the ?Form ID?), and any other documents
necessary or appropriate to obtain codes and passwords enabling the undersigned
to make electronic filings with the SEC of reports required by the Securities
Exchange Act of 1934, as amended (the ?Exchange Act?), or any rule or
regulation of the SEC;

(2) prepare, execute in the undersigned?s name and on the undersigned?s
behalf, and submit to the SEC, any and all Forms 3, 4, and 5 (the ?Section 16
Filings?), including amendments thereto, required to be filed under Section
16(a) of the Exchange Act and the rules thereunder with respect
to equity securities of the Company;

(3) do and perform any and all acts for and on behalf of the undersigned
which may be necessary or desirable to complete and execute such Form ID and
any Section 16 Filings and to file such Form ID and any Section 16 Filings with
the SEC and any stock exchange or similar authority; and

(4) take any other action of any type whatsoever in connection with the
foregoing which, in the opinion of such attorney-in-fact, may be of benefit to,
in the best interest of, or legally required by, the undersigned, it being
understood that the documents executed by such attorney-in-fact on behalf of
the undersigned pursuant to this Power of Attorney shall be in such form and
shall contain such terms and conditions as such attorney-in-fact may approve in
such attorney-in-fact's discretion.

	The undersigned hereby grants to each such attorney-in-fact full power and
authority to do and perform any and every act and thing whatsoever requisite,
necessary, or proper to be done in the exercise of any of the rights and powers
herein granted, as fully to all intents and purposes as the undersigned might
or could do if personally present, with full power of substitution
or revocation, hereby ratifying and confirming that each such attorney-in-fact,
or such attorney-in-fact's substitute or substitutes, shall lawfully do
or cause to be done by virtue of this power of attorney and the rights and
powers herein granted.  The undersigned hereby authorizes, approves, and
ratifies any and all prior actions taken by such attorneys-in-fact in
connection with the matters contemplated herein.  The undersigned acknowledges
that such attorneys-in-fact, in serving in such capacity at the request of
the undersigned, do not assume any of the undersigned's responsibilities to
comply with the Exchange Act or any rule or regulation of the SEC.

	This Power of Attorney shall remain in full force and effect until the
undersigned is no longer required to file a Form ID, any Section 16 Filings,
or any amendments or changes thereto, with respect to the undersigned?s
holdings of and transactions in securities issued by the Company, unless
earlier revoked by the undersigned in a signed writing delivered to
the foregoing attorneys-in-fact.

	IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be
executed as of the date first written above.




	By:  /s/ Sanj K. Patel
	Name:  Sanj K. Patel