EXIBIT32.1: CERTIFICATION OF PRINCIPAL EXECUTIVE OFFICER AND PRINCIPAL FINANCIAL
OFFICER  PURSUANT TO 18 U.S.C.  350,  AS ADOPTED  PURSUANT TO SECTION 906 OF THE
SARBANNES-OXLEY ACT OF 2002.*


      In connection  with the  accompanying  Quarterly  Report on Form 10-QSB of
Life  Medical  Sciences,  Inc.  for  the  quarter  ended  March  31,  2004,  the
undersigned  hereby  certifies  pursuant to 18 U.S.C.  Section  1350, as adopted
pursuant  to Section  906 of the  Sarbane-Oxley  Act of 2002,  to the best of my
knowledge and belief, that:

            (1)   such  Quarterly  Report on Form 10-QSB for the  quarter  ended
                  March 31, 2004 fully complies with the requirements of Section
                  13(a) or 15(d) of the Securities Exchange Act of 1934; and

            (2)   the  information  contained in such  Quarterly  Report on Form
                  10-QSB for the quarter  ended March 31, 2004 fairly  presents,
                  in all material respects,  the financial condition and results
                  of operations of Life Medical Sciences, Inc.

  April 30, 2004      /s/ Robert P. Hickey
                      --------------------
                      Name: Robert P. Hickey
                      Title: Chief Executive Officer and Chief Financial Officer

* A signed original of this written statement  required by Section 906, or other
document authenticating,  acknowledging or otherwise adopting the signature that
appears in typed form within the  electronic  version of this written  statement
required by Section 906, has been  provided by Life Medical  Sciences,  Inc. and
will be retained by Life Medical Sciences,  Inc. and furnished to the Securities
and Exchange Commission or its staff upon request.


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