EXHIBIT 32.1

                            CERTIFICATION PURSUANT TO
                             18 U.S.C. SECTION 1350,
                             AS ADOPTED PURSUANT TO
                  SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection  with the Annual Report of MISONIX,  INC. (the  "Company") on Form
10-K for the  period  ending  June 30,  2004 as filed  with the  Securities  and
Exchange  Commission on the date hereof (the  "Report"),  I, Michael A. McManus,
Jr., President and Chief Executive Officer of the Company,  certify, pursuant to
18 U.S.C. ss. 1350, as adopted pursuant to ss. 906 of the  Sarbanes-Oxley Act of
2002, that:

      (1)   The Report fully complies with the  requirements of section 13(a) or
            15(d) of the Securities Exchange Act of 1934; and

      (2)   The  information  contained in the Report  fairly  presents,  in all
            material respects,  the financial condition and result of operations
            of the Company.

      Dated: September 15, 2004

                                          /s/ Michael A. McManus, Jr.
                                          -------------------------------------
                                          Michael A. McManus, Jr.
                                          President and Chief Executive Officer

A signed  original of this written  statement  required by Section 906, or other
document authenticating, acknowledging, or otherwise adopting the signature that
appears in typed form within the  electronic  version of this written  statement
required by Section 906, has been provided to MISONIX, INC. and will be retained
by MISONIX,  INC. and furnished to the Securities and Exchange Commission or its
staff upon request.