UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT
     Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934

                        Date of Report: November 2, 2004

                                 CYTOMEDIX, INC.
             (Exact name of registrant as it appears in its charter)

         Delaware                    0-28443                     23-3011702
- ----------------------------  ------------------------      --------------------
(State or other jurisdiction  (Commission File Number)         (IRS Employer
    of incorporation)                                       Indentification No.)

                         416 Hungerford Drive, Suite 330
                            Rockville, Maryland 20850
              (Address of principal executive offices and zip code)

                                 (301) 251-2815
              (Registrant's telephone number, including area code)

Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

|_|   Written communications pursuant to Rule 425 under the Securities Act
      (17 CFR 230.425)

|_|   Soliciting material pursuant to Rule 14a-12 under the Exchange Act
      (17 CFR 240.14a-12)

|_|   Pre-commencement communications pursuant to Rule 14d-2(b) under the
      Exchange Act (17 CFR 240.14d-2(b))

|_|   Pre-commencement communications pursuant to Rule 13e-4(c) under the
      Exchange Act (17 CFR 240.13e-4(c))



Section 5--Corporate Governance and Management

Item 5.02 Departure of Directors or Principal Officers; Election of Directors;
Appointment of Principal Officers

(d) On November 1, 2004, Mr. James S. Benson accepted an appointment to fill a
vacancy on the Cytomedix, Inc. board of directors. Cytomedix issued the attached
press release announcing that Mr. Benson had accepted the appointment made by
the Cytomedix board of directors. The press release is filed as Exhibit 99.1 and
incorporated herein by reference.

Section 9--Financial Statements and Exhibits

Item 9.01  Financial Statements and Exhibits.

(c) Exhibits. The following Exhibit is furnished with this Current Report on
Form 8-K:

Exhibit No.       Description
- -----------       -----------

Exhibit 99.1      Press Release of Cytomedix, Inc., dated November 1, 2004.

                                   SIGNATURES

      Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                        CYTOMEDIX, INC.


                                        By: /s/ William Allender
                                           -------------------------------------
                                           William Allender
                                           Chief Financial Officer

Date: November 2, 2004