CERTIFICATION

      I, Robert P. Hickey, certify that:

      1. I have reviewed this quarterly report on Form 10-QSB of Life Medical
Sciences, Inc.;

      2. Based on my knowledge, this quarterly report does not contain any
untrue statement of a material fact or omit to state a material fact necessary
to make the statements made, in light of the circumstances under which such
statements were made, not misleading with respect to the period covered by this
quarterly report;

      3. Based on my knowledge, the financial statements, and other financial
information included in this quarterly report, fairly present in all material
respects the financial condition, results of operations and cash flows of the
registrant as of, and for, the periods presented in this report;

      4. The small business issuer's other certifying officers and I are
responsible for establishing and maintaining disclosure controls and procedures
(as defined in Exchange Act Rules 13a-14 and 15d-14) for the small business
issuer and we have:

            a) designed such disclosure controls and procedures, or caused such
      disclosure controls and procedures to be designed under our supervision,
      to ensure that material information relating to the small business issuer,
      including its consolidated subsidiaries, is made known to us by others
      within those entities, particularly during the period in which this
      quarterly report is being prepared;

            b) evaluated the effectiveness of the small business issuer's
      disclosure controls and presented in this report our conclusions about
      effectiveness of the disclosure controls and procedures, as of the end of
      the period covered by this report based on such evaluation; and

            c) disclosed in this report any change in the small business
      issuer's internal control over financial reporting that occurred during
      the small business issuer's most recent fiscal quarter (the small business
      issuer's fourth fiscal quarter in the case of an annual report) that has
      materially affected, or is reasonably likely to materially affect, the
      small business issuer's internal control over financial reporting; and

      5. The small business issuer's other certifying officers and I have
disclosed, based on our most recent evaluation of internal control over
financial reporting, to the small business issuer's auditors and the audit
committee of small business issuer's board of directors (or persons performing
the equivalent function):

            a) all significant deficiencies in the design or operation of
      internal control over financial reporting which are reasonably likely to
      adversely affect the small business issuer's ability to record, process,
      summarize and report financial information; and

            b) any fraud, whether or not material, that involves management or
      other employees who have a significant role in the small business issuer's
      ability to record, process, summarize and report financial information;
      and

      6. The small business issuer's other certifying officers and I have
indicated in this quarterly report whether or not there were significant changes
in internal controls or in other factors that could significantly affect
internal controls subsequent to the date of our most recent evaluation,
including any corrective actions with regard to significant deficiencies and
material weaknesses.


Dated: November 8, 2004                     By: /s/ Robert P. Hickey
                                               -------------------
                                               Robert P. Hickey
                                               Chief Executive Officer and
                                               Chief Financial Officer