EXIBIT  32.1:   CERTIFICATION  OF  PRINCIPAL  EXECUTIVE  OFFICER  AND  PRINCIPAL
FINANCIAL OFFICER PURSUANT TO 18 U.S.C. 1350, as adopted pursuant to Section 906
of the Sarbannes-Oxley Act of 2002.*


         In connection with the accompanying Quarterly Report on Form 10-QSB of
Life Medical Sciences, Inc. for the quarter ended September 30, 2004, the
undersigned hereby certifies pursuant to 18 U.S.C. Section 1350, as adopted
pursuant to Section 906 of the Sarbane-Oxley Act of 2002, to the best of my
knowledge and belief, that:

     (1)  such Quarterly  Report on Form 10-QSB for the quarter ended  September
          30, 2004 fully  complies  with the  requirements  of Section  13(a) or
          15(d) of the Securities Exchange Act of 1934; and

     (2)  the information  contained in such Quarterly Report on Form 10-QSB for
          the quarter ended September 30, 2004 fairly presents,  in all material
          respects,  the  financial  condition and results of operations of Life
          Medical Sciences, Inc.



         November 8, 2004        /s/ Robert P. Hickey
                                 --------------------
                                 Name: Robert P. Hickey
                                 Title: Chief Executive Officer and
                                 Chief Financial Officer

* A signed original of this written statement required by Section 906, or other
document authenticating, acknowledging or otherwise adopting the signature that
appears in typed form within the electronic version of this written statement
required by Section 906, has been provided by Life Medical Sciences, Inc. and
will be retained by Life Medical Sciences, Inc. and furnished to the Securities
and Exchange Commission or its staff upon request.