[RICHARDSON & PATEL LETTERHEAD]

                                December 30, 2004


VIA EDGAR AND FEDERAL EXPRESS
Securities and Exchange Commission
450 Fifth Street, N.W.
Washington, D.C. 20549


        Re:  Bio-Bridge Science, Inc.
             Registration Statement on Form SB-2


Ladies and Gentlemen:

         On behalf of Bio-Bridge Science,  Inc.  ("Bio-Bridge")  pursuant to the
Securities Act of 1933, as amended,  and Regulation S-T promulgated  thereunder,
we hereby transmit for filing via EDGAR Bio-Bridge's  Registration  Statement on
Form SB-2  with  copies of  exhibits  thereto  for the  purpose  of  registering
3,657,606  shares of common  stock on behalf of  certain  selling  stockholders.
Manually  executed  signature  pages and consents  have been signed prior to the
time of this  electronic  filing and will be  retained  by  Bio-Bridge  for five
years.   Enclosed  herewith  are  three  copies  of  Bio-Bridge's   Registration
Statement, as transmitted for filing via EDGAR on the date hereof.

         Pursuant to Rule  457(o),  Bio-Bridge  has  computed the fee due on the
basis of $0.50 per  share.  Pursuant  to Rule  13(c) of  Regulation  S-T, a wire
transfer in the amount of $216.00 was wired to Mellon  Bank in  connection  with
this filing.

         Please  direct any questions or comments  regarding  this filing to the
undersigned or Michael Donahue of this office at 310-208-1182.



                                    Very truly yours,

                                    RICHARDSON & PATEL LLP

                                    /s/ Dorothy B. Vinski

                                    Dorothy B. Vinski

Enclosures