UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                              WASHINGTON, DC 20549

                                   FORM 8-K/A

                                 CURRENT REPORT
                     PURSUANT TO SECTION 13 OR 15(D) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

                                 Date of Report
              (Date of earliest event reported): December 20, 2004

                              ENHANCE BIOTECH, INC.

               (Exact Name of Registrant as Specified in Charter)

           Delaware                    000-31653                 95-4766094
(State or Other Jurisdiction   (Commission File Number)        (IRS Employer
      of Incorporation)                                      Identification No.)

                712 Fifth Avenue, 19th Floor, New York, NY 10019
               (Address of principal executive offices) (Zip code)

                                 (646) 723 8940
              (Registrant's telephone number, including area code)

                                 Not Applicable
          (Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

|_|   Written  communications  pursuant to Rule 425 under the Securities Act (17
      CFR 230.425)

|_|   Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
      240.14a-12)

|_|   Pre-commencement  communications  pursuant  to  Rule  14d-2(b)  under  the
      Exchange Act (17 CFR 240.14d-2(b))

|_|   Pre-commencement  communications  pursuant  to  Rule  13e-4(c)  under  the
      Exchange Act (17 CFR 240.13e-4(c))

The  Registrant  hereby amends the Current  Report on Form 8-K filed on December
27, 2004 (the "Current Report"),  which reported the completion of the merger of
Ardent  Acquisition Corp, a wholly owned subsidiary of the Registrant,  with and
into  Ardent   Pharmaceuticals,   Inc.  As  a  result  of  the  merger,   Ardent
Pharmaceuticals,  Inc. became a wholly owned subsidiary of the Registrant.  This
amendment to the Current Report provides audited financial statements for Ardent
Pharmaceuticals,  Inc. and  unaudited  pro forma  condensed  combined  financial
statements of the Registrant and Ardent Pharmaceuticals, Inc.


SECTION 5 - CORPORATE GOVERNANCE AND MANAGEMENT

ITEM 5.03  AMENDMENTS  TO THE  ARTICLES OF  INCORPORATION  OR BYLAWS;  CHANGE IN
FISCAL YEAR

(b) On March 23,  2005,  the Board of  Directors  of the  Registrant  elected to
change the date of the Registrant's  fiscal year end from January 31 to December
31. The Company will report the transition period on Form 10-KSB

SECTION 9 - FINANCIAL STATEMENTS AND EXHIBITS

ITEM 9.01 FINANCIAL STATEMENTS AND EXHIBITS.

(a) Financial statements of business acquired.

Financial statements of Ardent Pharmaceuticals, Inc. for the year ended December
31, 2004

Report of Independent Registered Public Accounting Firm
Balance Sheet
Statement of Operations
Statement of Stockholders Deficit
Statement of Cash Flows
Notes to Financial Statements


             REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

The Board of Directors and Stockholders
Ardent Pharmaceuticals, Inc.

We have audited the accompanying balance sheet of Ardent Pharmaceuticals, Inc.
(the "Company") as of December 31, 2004, and the related statements of
operations, stockholders' deficit and cash flows for the year then ended. These
financial statements are the responsibility of the Company's management. Our
responsibility is to express an opinion on these financial statements based on
our audit.

We conducted our audit in accordance with the standards of the Public Company
Accounting Oversight Board (United States). Those standards require that we plan
and perform the audit to obtain reasonable assurance about whether the financial
statements are free of material misstatement. An audit includes examining, on a
test basis, evidence supporting the amounts and disclosures in the financial
statements. An audit also includes assessing the accounting principles used and
significant estimates made by management, as well as evaluating the overall
financial statement presentation. We believe that our audits provide a
reasonable basis for our opinion.

In our opinion, such financial statements present fairly, in all material
respects, the financial position of the Company as of December 31, 2004, and the
results of its operations and its cash flows for the year then ended, in
conformity with accounting principles generally accepted in the United States of
America.

The accompanying financial statements have been prepared assuming the Company
will continue as a going concern. At December 31, 2004, the Company has an
accumulated deficit of $69,000,000, negative working capital, and liabilities
that exceed assets by $2,300,000. These factors create substantial doubt about
the Company's ability to continue as a going concern. Management's plans
regarding this matter are described in Note 8. The financial statements do not
include any adjustments that might be necessary if the Company is unable to
continue as a going concern.


                      /s/ CACCIAMATTA ACCOUNTANCY CORPORATION

Irvine, California
March 9, 2005


                          ARDENT PHARMACEUTICALS, INC.

                                  BALANCE SHEET
                             As of December 31, 2004

                                     ASSETS
Current assets
    Cash and cash equivalents                                      $    370,585
    Accounts receivable                                                 110,030
                                                                   ------------
               Total current assets                                     480,615

Property and equipment, net of accumulated
    depreciation and amortization of $1,915,413                         755,275
Patents, net of accumulated amortization of $72,016                     576,943
Other long term assets                                                   11,405
                                                                   ------------
                                                                   $  1,824,238
                                                                   ============

                      LIABILITIES AND STOCKHOLDERS' DEFICIT
Current liabilities
    Accounts payable                                               $    285,767
    Accrued interest due to affiliate                                   457,908
    Current portion of long-term debt                                   119,042
    Other liabilities                                                    15,450
    Current portion of deferred revenue                                  60,000
                                                                   ------------
               Total current liabilities                                938,167

Deferred revenue, less current portion                                1,190,000
Long-term debt, less current portion                                     55,560
Covertible note payable to affiliate                                  1,925,028
                                                                   ------------
               Total liabilities                                      4,108,755
                                                                   ------------

Stockholders' deficit
    Preferred stock, no par value, 20,000,000 shares authorized
      Series A convertible preferred stock,
         120,150 shares issued and outstanding                       12,015,000
      Series B convertible exchangeable preferred stock,
         120,150 shares issued and outstanding                       12,015,000
      Series C preferred stock,
         1,000,000 shares issued and outstanding                      4,117,648
      Series D-1 convertible preferred stock,
         795,715 shares issued and outstanding                          640,453
         Accretion of series D-1 dividends                              163,618
      Series D-2 convertible preferred stock,
         2,453,333 shares issued and outstanding                      1,897,806
         Accretion of series D-2 dividends                              172,960
    Common stock, no par value, 100,000,000 shares authorized
      23,320,969 shares issued and outstanding                       34,797,476
    Warrants                                                            915,314
    Accumulated deficit                                             (69,019,792)
                                                                   ------------
               Total stockholders' deficit                           (2,284,517)
                                                                   ------------

                                                                   $  1,824,238
                                                                   ============

                 See accompanying notes to financial statements.



                          ARDENT PHARMACEUTICALS, INC.

                             STATEMENT OF OPERATIONS
                      For the Year ended December 31, 2004

Revenues
    License fees                                                   $    123,168
                                                                   ------------

Operating costs and expenses
    Research and development                                         (1,768,255)
    General and administrative                                       (3,551,677)
                                                                   ------------
      Total costs and expenses                                       (5,319,932)
                                                                   ------------

        Loss from operations                                         (5,196,764)

Other income (expense)
    Interest income                                                      20,235
    Interest expense                                                   (236,893)
                                                                   ------------

Net loss                                                             (5,413,422)

Accretion of dividends on preferred stock                              (877,435)
                                                                   ------------

        Net loss applicable to common stockholders                 $ (6,290,857)
                                                                   ============

Net loss per common share - basic and diluted                      $      (0.28)
                                                                   ============

Weighted average common shares outstanding - basic and diluted       22,165,000
                                                                   ============

                 See accompanying notes to financial statements.



                          ARDENT PHARMACEUTICALS, INC.

                       STATEMENT OF STOCKHOLDERS' DEFICIT
                      For the Year ended December 31, 2004



                               Balance          Accretion of       Conversions to   Options          2004            Balance
                              31-Dec-03          Dividends          Common Stock    Granted        Net Loss         31-Dec-04
                             ------------       ------------       --------------   -------       -----------      ------------
                                                                                                 
PREFERRED STOCK

  Series A
   No. of Shares                  120,150                                                                               120,150
   Amount                    $ 12,015,000                                                                          $ 12,015,000
   Dividend                  $  2,746,103           330,316         (3,076,419)                                    $         --

  Series B
   No. of Shares                  120,150                                                                               120,150
   Amount                    $ 12,015,000                                                                          $ 12,015,000
   Dividend                  $  2,357,493           329,894         (2,687,387)                                    $         --

  Series C
   No. of Shares                2,428,571                           (1,428,571)                                       1,000,000
   Amount                    $ 10,000,000                           (5,882,352)                                    $  4,117,648

  Series D-1
   No. of Shares                  795,715                                                                               795,715
   Amount                    $    640,453                                                                          $    640,453
   Dividend                  $     58,020           105,598                                                        $    163,618

  Series D-2
   No. of Shares                2,453,333                                                                             2,453,333
   Amount                    $  1,897,806                                                                          $  1,897,806
   Dividend                  $     61,333           111,627                                                        $    172,960

COMMON STOCK

  No. of Shares                21,173,759                            2,147,210                                       23,320,969
  Amount                     $ 23,073,595                           11,662,479       61,402                        $ 34,797,476
  Warrants                   $    931,531                              (16,217)                                    $    915,314

ACCUMULATED DEFICIT          $(62,728,935)         (877,435)                                       (5,413,422)     $(69,019,792)

DEFERRED COMPENSATION        $    (55,693)                              55,693                                     $         --

                             --------------------------------------------------------------------------------------------------
TOTAL                        $  3,011,706         $      --           $ 55,797      $61,402       $(5,413,422)     $ (2,284,517)
                             ==================================================================================================


         See accompanying notes to financial statements.



                          ARDENT PHARMACEUTICALS, INC.

                             STATEMENT OF CASH FLOWS
                      For the Year ended December 31, 2004

Cash flows from operating activities
    Net loss                                                       $ (5,413,422)
    Non-cash items included in net loss
      Amortization and impairment of patents                            177,346
      Depreciation                                                      424,482
      Stock-based compensation                                          117,095
    Changes in operating assets and liabilities
         Accounts receivable                                           (104,715)
         Prepaid expenses                                                 4,809
         Accounts payable                                               (36,394)
         Accrued interest due to affiliate                              197,415
         Other liabilities                                                6,050
         Deferred revenue                                             1,250,000
                                                                   ------------
             Net cash used in operating activities                   (3,377,334)
                                                                   ------------
Cash flows from investing activities
    Purchase of property and equipment                                   (6,270)
                                                                   ------------
             Net cash used in investing activities                       (6,270)
                                                                   ------------
Cash flows from financing activities
    Proceeds from issuance of common stock                                  104
    Principal payments on long-term debt                               (202,648)
                                                                   ------------
             Net cash used in financing activities                     (202,544)
                                                                   ------------
             Net decrease in cash and cash equivalents               (3,586,148)
Cash and cash equivalents, at beginning of period                     3,956,733
                                                                   ------------
Cash and cash equivalents, at end of period                        $    370,585
                                                                   ============

Supplemental disclosure of cash flow information
    Cash paid for interest                                         $     43,726
                                                                   ============
    Cash paid for income taxes                                     $         --
                                                                   ============

Supplemental disclosure of non-cash investing and
  financing information
    Conversion of preferred stock to common stock                  $ 11,662,479
                                                                   ============

                 See accompanying notes to financial statements.


                          ARDENT PHARMACEUTICALS, INC.

                          NOTES TO FINANCIAL STATEMENTS
                        For Year ended December 31, 2004

(1)   ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

      ORGANIZATION

      Ardent Pharmaceuticals,  Inc. ("Company" or "Ardent"), was incorporated in
      North Carolina in 1995 to  commercialize  pharmaceutical  products focused
      primarily on the delta receptor. The Company is engaged in the development
      of new drug  candidates,  primarily  in the  markets  of pain  management,
      urinary    incontinence,    premature    ejaculation,    depression    and
      cardio-protection, among others.

      The Company faces risks  associated  with companies  whose products are in
      preclinical and clinical development.  These risks include,  among others,
      the  Company's  need for  additional  financing to complete the  research,
      development  and  clinical  testing  necessary  to bring its  products  to
      market. The Company has incurred net losses since inception and has funded
      those losses primarily  through the sale of equity.  There is no assurance
      such  financing will continue to be available to the Company when required
      or that such financing would be available under favorable terms.

      USE OF ESTIMATES

      The  preparation  of financial  statements in conformity  with  accounting
      principles  generally  accepted in the United  States of America  requires
      management  to make  estimates  and  assumptions  that affect the reported
      amounts of assets and liabilities and disclosure of contingent  assets and
      liabilities  at the  date of the  financial  statements  and the  reported
      amounts of revenues  and  expenses  during the  reporting  period.  Actual
      results could differ from those estimates.

      CASH AND CASH EQUIVALENTS

      The Company  considers all highly liquid debt instruments with an original
      maturity  at  date  of  purchase  of  three  months  or  less  to be  cash
      equivalents.  Included in cash and cash  equivalents is restricted cash of
      $61,110 which secures a $61,000 letter of credit.

      PROPERTY AND EQUIPMENT

      Property and equipment are recorded at cost.  Depreciation on property and
      equipment is calculated using the straight-line  method over the estimated
      useful lives,  which are three to five years.  Leasehold  improvements are
      amortized using the straight-line method over the lesser of the lease term
      or estimated useful life. Expenses for repairs and maintenance are charged
      to operations as incurred. Upon retirement or sale, the cost of the assets
      disposed of and the related accumulated  depreciation are removed from the
      accounts,  and  any  resulting  gain or loss is  credited  or  charged  to
      operations. Property and equipment consist of the following:

            Leasehold improvements                                  $ 1,255,640
            Furniture and equipment                                   1,415,048
                                                                    -----------
                                                                      2,670,688
            Accumulated depreciation and amortization                (1,915,413)
                                                                    -----------
                                                                    $   755,275
                                                                    ===========



(1)   ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (CONTINUED)

      PATENTS

      Costs directly  related to filing patent  applications are capitalized and
      amortized using the straight-line method over the estimated useful life of
      the patent from the date of grant. The Company assesses the recoverability
      of this  intangible  asset at least annually based on the expected  future
      economic  benefit  to be  derived  from  the  underlying  patent  over its
      remaining  useful life. A patent  impairment  charge of $150,181 was taken
      against the patent portfolio after a review of the portfolio  conducted as
      of  December  31,  2004.  The net book  value of the patent  portfolio  is
      $576,943 ($648,959 less accumulated amortization of $72,016.)

      IMPAIRMENT OF LONG-LIVED ASSETS

      The Company evaluates the recoverability of its long-lived assets annually
      and when  circumstances  indicate  that an event  of  impairment  may have
      occurred in  accordance  with the  provisions  of  Statement  of Financial
      Accounting  Standard  ("SFAS") No. 144,  "Accounting for the Impairment or
      disposal of Long-Lived Assets".

      FAIR VALUE OF FINANCIAL INSTRUMENTS

      The Company  has  determined  the  estimated  fair value of its  financial
      instruments.  Due to their short-term nature, the carrying values for cash
      and cash equivalents,  accounts  receivable,  prepaid  expenses,  accounts
      payable and accrued expenses approximate their fair values. The historical
      carrying  value of the Company's  long-term debt  approximated  fair value
      because  the  interest  rates  on  these  obligations   approximate  rates
      currently available to the Company.

      REVENUE RECOGNITION

      License fee revenue is recognized under collaborative  research agreements
      when  services are  performed  or when  contractual  obligations  are met.
      Nonrefundable fees received at the initiation of collaboration  agreements
      for  which  the  Company  has  an  ongoing  research  and  development  or
      commercial commitments are deferred and recognized ratably over the period
      of the related research, development or commercial commitments.  Milestone
      payments  under  collaboration  agreements  and  research  agreements  are
      recognized as revenues ratably over the remaining period of involvement by
      the Company in the  research,  development  and  commercialization  of the
      asset beginning on the date the Company  achieves the indicated  milestone
      and such achievement is acknowledged by the collaborative  partner,  which
      generally  coincides with the receipt of the milestone  payment.  Research
      grants revenues are recognized as the related research is performed.

      RESEARCH AND DEVELOPMENT EXPENSE

      Research  and  development  direct  and  indirect  costs are  expensed  as
      incurred and include all costs  associated  with the  development  of drug
      compounds.

      EMPLOYEE BENEFIT PLANS

      All  eligible  employees  may  elect to have a  portion  of  their  salary
      contributed to the Company's  401(k) Plan.  Ardent does not match employee
      contributions.

      In 2004, Ardent terminated a non-qualified  deferred  compensation  Trust,
      which permitted eligible employees to defer up to 50% of their salary, and
      distributed all Trust assets to the Trust beneficiary.


(1)   ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (CONTINUED)

      INCOME TAXES

      Deferred  tax assets and  liabilities  are  recognized  for the future tax
      consequences  attributable  to  differences  between  financial  statement
      carrying  amounts of existing assets and liabilities and their  respective
      tax bases.  Deferred tax assets and liabilities are measured using enacted
      tax rates  expected to apply to taxable income in the years in which those
      temporary  differences are expected to be recovered or settled. The effect
      on  deferred  tax  assets  and  liabilities  of a change  in tax  rates is
      recognized  in income in the period  that  includes  the  enactment  date.
      Valuation  allowances are established  when necessary to reduce tax assets
      to the amounts that are to be realized.

      STOCK BASED COMPENSATION

      SFAS No. 148,  Accounting for  Stock-Based  Compensation -- Transition and
      Disclosure -- an amendment of FASB Statement No. 123 provides  alternative
      methods of  transition  for a  voluntary  change to the fair  value  based
      method  of  accounting  for  stock-based  employee  compensation  from the
      intrinsic  value-based method of accounting  prescribed by APB Opinion No.
      25,  Accounting  for Stock Issued to  Employees.  . As allowed by SFAS No.
      123,  the  Company  has  elected  to  continue  to  apply  the   intrinsic
      value-based   method  of   accounting   prescribed  in  APB  No.  25  and,
      accordingly,  does not  recognize  compensation  expense for stock  option
      grants made to employees at an exercise price equal to or in excess of the
      fair  value of the stock at the date of grant.  Deferred  compensation  is
      recognized and amortized on an accelerated  basis in accordance  with FASB
      Interpretation No. 28, Accounting for Stock Appreciation  Rights and Other
      Variable  Stock  Option or Award  Plans,  over the  vesting  period of the
      related options.

      For non-employee  awards, the Company is required to follow the provisions
      of SFAS  No.  123 and EITF  96-18,  which  require  that  compensation  be
      measured at the end of each reporting period for changes in the fair value
      of the Company's common stock until the options are vested.

      The Company utilized the following  assumptions in the Black-Scholes  fair
      value calculation model at December 31, 2004:

            Estimated dividend Yield                                 0.0%
            Expected stock price volatility                         60.0%
            Risk-free interest rate                                 4.75%
            Expected life of options - employees                  4 years
            Expected life of options - non-employees             10 years

    Had the Company elected to recognize compensation expense based on the
    estimated fair value of stock-based instruments at the grant date, as
    prescribed by SFAS 123, its pro forma net loss and net loss per common share
    would have been as follows:

            Net loss - as reported                                  $(6,290,857)
            Less fair value of options granted employees               (104,605)
                                                                    -----------
            Net loss - pro forma                                    $(6,395,462)

            Net loss per common share - as reported                 $     (0.28)
            Net loss per common share - pro forma                   $     (0.29)

    The effects of applying SFAS No. 123 in this pro forma disclosure are not
    indicative of future amounts. Stock option grants are expensed over their
    respective vesting periods.



(1)   ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (CONTINUED)

      NET LOSS PER COMMON SHARE

      Basic and diluted net loss per common  share is  presented  in  conformity
      with SFAS No. 128,  "Earnings  per Share".  Basic and diluted net loss per
      common share has been computed using the weighted-average number of shares
      of common stock outstanding  during the period.  The assumed conversion of
      convertible  stock and  related  accumulated  stock  dividends,  and other
      outstanding common stock equivalents, were not included in the computation
      of weighted average common shares outstanding  because the impact of their
      assumed conversion would be anti-dilutive.

            Numerator - Net loss                                   $  6,290,857
            Denominator-Weighted average shares outstanding          22,165,000
            Net loss per share                                     $      (0.28)

            Incremental common shares outstanding at December 31, 2004
            (not included because of their anti-dilutive nature):
            Common Stock Options                                      5,439,360
            Warrants                                                  1,218,046
                                                                   ------------
                                                                      6,657,406
                                                                   ============

      COMPREHENSIVE LOSS

      Comprehensive  income  (loss) is defined as all changes in a company's net
      assets,  except changes resulting from transactions with shareholders.  At
      December 31, 2004, the Company has no reportable  differences  between net
      loss and comprehensive loss.

      SEGMENT REPORTING

      The Company has determined that it does not have any separately reportable
      operating segments.

      RECENTLY ISSUED ACCOUNTING STANDARDS

      In December  2004 the FASB issued SFAS No.  123R,  "Share-Based  Payment,"
      which  is an  amendment  to SFAS  No.  123,  "Accounting  for  Stock-Based
      Compensation."  This new  standard  eliminates  the ability to account for
      share-based  compensation  transactions using Accounting Principles Board,
      or APB,  Opinion No. 25,  "Accounting  for Stock Issued to Employees," and
      generally   requires   such   transactions   be  accounted   for  using  a
      fair-value-based method and the resulting cost recognized in our financial
      statements.  This new standard is  effective  for awards that are granted,
      modified or settled in cash in interim and annual periods  beginning after
      June 15, 2005 (December 15, 2005 for small business issuers). In addition,
      this  statement  will  apply  to  unvested  options  granted  prior to the
      effective date. The Company will adopt this new standard effective for the
      first  fiscal  quarter of 2006 and it has not yet  determined  what impact
      this  standard  will  have  on  its  financial   position  or  results  of
      operations.


(2)   RESEARCH & DEVELOPMENT AND LICENSE AGREEMENTS

      LICENSE AGREEMENTS - DEFERRED REVENUE

      During 1999, the Company granted a license to N.V.  Organon AG ("Organon")
      to use the Company's  patent rights in the development,  manufacture,  use
      and sale of one of its analgesic  compounds (the "License").  Organon made
      nonrefundable  cash  payments  to the Company of $1 million and $3 million
      during  1999 and 2000,  respectively.  These  payments  were  recorded  as
      deferred  revenue and were being  amortized to revenue on a  straight-line
      basis over the period of time the Company  expected  to be  involved  with
      Organon in developing the technology.  During March 2003, Organon notified
      the Company of its intention to discontinue  development of DPI-3290 under
      the License. Subsequent to this notification,  Ardent delivered to Organon
      a  notification  of  termination  of the  agreement  for  cause.  With the
      termination of the License and any rights thereunder, the remainder of the
      deferred License revenue was recognized in 2003.

      By letter to the Company,  dated  January 11, 2005,  Organon  asserted its
      belief that it maintains  certain  rights  under the License.  The Company
      believes this claim is without merit and has initiated dispute  resolution
      procedures  specified  in the License to confirm that the License has been
      terminated and that Organon has no further rights thereunder.

      During 2004 the Company  announced  that it had entered into a Feasibility
      Study,  Option and License  Agreement with ALZA Corporation (a division of
      Johnson & Johnson) for the  development of DPI-125 for  moderate-to-severe
      pain. In  consideration  of an initial  non-refundable  fee of $1,250,000,
      Ardent granted ALZA a 12-month option for an exclusive,  worldwide license
      to the compound. During the 12-month period, ALZA will conduct feasibility
      studies.  If ALZA exercises the option, ALZA will proceed with development
      of at least two potential products,  an intravenous  formulation for acute
      pain and at least one formulation for chronic pain. ALZA may also elect to
      develop other  formulations  of DPI-125.  The agreement also provides ALZA
      with exclusive options to license additional  analgesic compounds from the
      Ardent  portfolio.  Development  and  commercialization  expenses  for the
      products will be borne by ALZA. In addition to the option fee upon signing
      the agreement,  Ardent will receive further  payments should ALZA exercise
      its option following  feasibility  studies,  and will also be eligible for
      development milestone payments and royalties. Ardent also has the right to
      co-promote the intravenous product in the US.

      The Company completed  delivery to ALZA of certain quantities of compounds
      required by the agreement during December 2004. Beginning in January 2005,
      the  Company  will  amortize  the initial  $1,250,000  fee to revenue on a
      straight-line  basis  over the  period of time the  Company  expects to be
      involved with ALZA in developing and commercializing  the technology.  Any
      subsequent  payments or development  milestones payments will be amortized
      to revenue on a similar  basis.  The  Company  paid a cash fee of $150,000
      plus  issuance of 40,000  options to Century  Capital as the agent in this
      transaction.

(3)   STOCKHOLDERS' EQUITY

      TRANSACTION WITH XENOBIOTIC LABORATORIES INC

      In 1997, the Company issued 3,400,000 shares of common stock to XenoBiotic
      Laboratories Inc (XenoBiotic). The Company has a right-of-first-refusal to
      repurchase  those shares from XenoBiotic at the same terms as offered by a
      third party.


(3)   STOCKHOLDERS' EQUITY (CONTINUED)

      TRANSACTIONS WITH ELAN

      In 1999 and  2000,  the  Company  formed  two  joint  ventures  with  Elan
      Corporation  (Elan) which were terminated in 2002 and 2003. In conjunction
      with the formation of the joint  ventures,  Elan was issued 120,150 shares
      each of Series A and  Series B  preferred  stock.  Both  series  accrue 5%
      dividends that compound  semi-annually (Series A) and annually (Series B),
      payable  either in-kind or in cash, at the Company's  option.  Both series
      are  convertible  through  2005  (Series A) and 2006  (Series B) at $7 per
      share  (Series A) and $10 per share  (Series B).  Both series  mandatorily
      convert with the consummation of an initial public  offering.  Both series
      carry a liquidation preference equal to the original proceeds plus accrued
      dividends.  The  liquidation  preference is payable only in the event of a
      liquidation,  dissolution or winding-up of the affairs of the Company,  as
      defined.  During  2004,  all  Series  A and  B  dividends  accreted  since
      inception  were paid in-kind by the  issuance of 439,488  shares of common
      stock, valued at $3,076,419 (Series A), and 268,734 common shares,  valued
      at $2,687,387 (Series B).

      During 2000,  the Company  issued  2,428,571  shares of Series C Preferred
      Stock  ("Series C") to Elan for total  proceeds of  $10,000,000.  Series C
      allows Elan to  participate  equally  with the holders of common  stock in
      dividends if and when declared by the Board of Directors and entitles Elan
      to convert  Series C into  common  stock at a ratio of one share of common
      stock for one share of Series C. Series C has no  preferential  terms over
      common   stock  and   mandatorily   converts  to  common  stock  with  the
      consummation of an initial public offering.

      During 2004 Elan sold all their Series A, Series B, and common  shares and
      1,000,000 of their Series C shares to Scarlet  Knights,  and converted the
      remaining  1,428,571  shares  of  Series C into an equal  number of common
      shares, valued at $5,882,352.

      SERIES D

      During 2003, the Company  exchanged  795,715 shares of common stock valued
      at $640,453,  for equal shares of Series D-1  Preferred  Stock ("D-1)" and
      sold  2,453,333  shares of Series D-2  Preferred  Stock  ("D-2") for total
      proceeds of  $2,944,000.  Both Series D accrue 5% dividends  that compound
      annually  which,  when paid, are payable either in-kind or in cash, at the
      Company's  option.  D-1  shares  are  convertible  at any time  after  the
      Original Issue Date.

      D-2 shares are  convertible  upon the first  occurrence  of a  liquidation
      event or qualifying  financing,  as defined.  Both series will mandatorily
      convert with the consummation of an initial public  offering.  Both series
      carry a liquidation preference equal to the original proceeds plus accrued
      dividends. Upon any liquidation, dissolution or winding up of the Company,
      holders of D-2 stock shall be entitled,  before any  distribution  is made
      upon the  common  stock,  to be paid an amount  equal to two times the D-2
      price per share,  plus any declared but unpaid  dividends,  and holders of
      D-1 stock  shall be  entitled  to an amount  equal to the  original  issue
      price. In addition,  the Company issued the D-2  shareholders  one warrant
      for every two D-2  shares  exercisable  at $0.01 per  share.  Using a fair
      value-pricing model, the Company determined the value of the preferred D-2
      Series and the warrants to be $1,897,806 and $931,531, respectively, after
      deducting  fundraising  expenses  of $76,824  and  $37,839,  respectively.
      During  2004,  10,417  common  shares were issued upon the  exercise of an
      equal number of warrants.

      COMMON STOCK OPTIONS

      Under the Company's  1997 Stock Award Plan, as amended,  5,000,000  common
      shares have been reserved for granting options to employees,  directors or
      consultants.  At December 31, 2004, 4,062,000 options had been granted and
      938,000 options were available for grant. In addition, the Company granted
      1,377,360  options  outside the Plan. The option strike price is generally
      the  fair  value  of the  Company  stock  as  determined  by the  board of
      directors.


(3)   STOCKHOLDERS' EQUITY (CONTINUED)

      A summary of options activity during 2004 follows:

                                                    Number     Weighted Average
                                                  of Shares     Exercise Price
                                                  ----------      ----------
            Balances as of December 31, 2003       4,571,860      $     0.56
              Granted                              1,087,500            0.60
              Cancelled                             (220,000)           0.60
                                                  ----------      ----------
            Balances as of December 31, 2004       5,439,360      $     0.57
                                                  ==========      ==========
            Exercisable as of December 31, 2004    3,838,860      $     0.56
                                                  ==========      ==========

      Additional information concerning options outstanding at December 31, 2004
      follows:

                                     Number of    Weighted Average
                  Exercise Price       Shares      Remaining Life
                  ------------------------------------------------
                      $ 0.25            330,000         2.21
                      $ 0.35             85,000         2.34
                      $ 0.50            479,000         3.44
                      $ 0.60          4,545,360         8.33
                  ------------------------------------------------
                  $ 0.25 - 0.60       5,439,860         7.44
                  ================================================

      Compensation  expense for  non-employee  stock options granted in 2004 was
      61,402.  Had the Company valued employee stock options at fair value using
      the minimum value  method,  compensation  expense would have  increased by
      approximately  $104,605.  The  fair  value  of  common  stock  options  is
      estimated  on the date of grant  using  the  Black-Scholes  option-pricing
      model.

      WARRANTS

      At  December  31,  2004,   there  are  1,218,046   common  stock  warrants
      outstanding that are exercisable at $0.01 to $3.50 and expire between July
      2005 and October 2010.

(4)   CONVERTIBLE NOTE PAYABLE TO AFFILIATE

      Under the joint venture  agreements  with Elan,  discussed in note 3, Elan
      loaned the Company  $1,925,028 in convertible debt financing,  maturing on
      April 14, 2006. Interest accrues at 9% per annum,  compounded on an annual
      basis.  Elan has the right to convert  outstanding debt into the number of
      common  shares  that is obtained by  dividing  outstanding  principal  and
      interest  by  $7.50.  At  December  31,  2004,  accrued  interest  totaled
      $457,908.

(5)   INCOME TAXES

      The provision for income taxes consists of current income tax expense. The
      reasons for the difference  between the actual  provision for income taxes
      and the amount computed by applying the statutory federal rate to net loss
      are:

            Net loss before provision for income taxes              $(5,413,422)
            Income tax (benefit) at statutory rate                   (1,841,000)
            State income taxes, net of federal tax benefit             (246,000)
            Change in valuation allowance                             2,167,000
            Non-deductible expenses                                      44,000
            Credits generated in current year                          (124,000)
                                                                    -----------
            Provision for income taxes                              $        --
                                                                    ===========


(5)   INCOME TAXES (CONTINUED)

      There are no deferred tax liabilities.  The components of the deferred tax
      assets are:

            Net operating loss carryforwards                       $ 22,333,000
            Research and development tax credits                      1,073,000
            Stock based compensation                                    862,000
            Depreciation and amortization                               150,000
            Deferred Income                                             482,000
            Less valuation allowance                                (24,900,000)
                                                                   ------------
            Deferred tax asset, net of valuation allowance         $         --
                                                                   ============

      The valuation allowance increased $2,167,000 in 2004.

      As of December 31, 2004,  the Company had federal and state income tax net
      operating  loss  carryforwards  of  approximately  $31,829,000,  which are
      available to offset future taxable income and expire between 2018 and 2024
      for federal income taxes and between 2013 and 2019 for state income taxes.
      Additionally, the Company has federal tax research and development credits
      of  approximately  $1,073,000 with expiration  dates through 2024. The Tax
      Reform Act of 1986 contains  provisions which limit the ability to utilize
      the  net  operating  loss  carryforwards  in the  case of  certain  events
      including significant changes in ownership interests. If the Company's net
      operating  loss  carryforwards  are  limited,  and the Company has taxable
      income  which  exceeds  the   permissible   yearly  net   operating   loss
      carryforward,  the Company would incur a federal income tax liability even
      though net  operating  loss  carryforwards  would be  available  in future
      years.

(6)   LONG-TERM DEBT

      The Company  entered into an equipment  lease financing line of $1,300,000
      and issued  warrants to the lender for the  purchase of a number of shares
      of common stock equal to the result of dividing 4.5% of the loan amount by
      the share price of the most recent  prior  round of equity  financing,  as
      defined. No additional funding is available under this line as of December
      31, 2004.  Borrowings under the financing  agreement are collateralized by
      the related equipment and furniture and fixtures. The borrowings mature in
      three to four years after the date of the borrowing with interest rates of
      between  12%-13%.  The aggregate  annual  maturities of long-term  debt at
      December 31, 2004, are:

                         2005             $119,042
                         2006               55,560
                                          --------
                                          $174,602
                                          ========

(7)   TRANSACTIONS WITH AFFILIATES

      CENTURY CAPITAL ASSOCIATES

      David  LaVance,  a former  Company  Director,  is a managing  director  of
      Century  Capital  Associates  (CCA).  CCA provides  business and financial
      consulting  services to the Company.  CCA received $660,105 from Ardent in
      2004; $500,000 related to merger costs,  $150,000 related to commission on
      the Alza licensing agreement and $10,105 in expense reimbursements.


(7)   TRANSACTIONS WITH AFFILIATES (CONTINUED)

      JINN WU

      Jinn Wu, a Company  Director,  is President and CEO of XenoBiotic,  a firm
      that performs  contract  research for the Company.  Mr. Wu and XenoBiotics
      received $88,570 from Ardent in 2004 for laboratory services.

      In  March  2004,  the  Company  issued  100,000  options  to a Jinn  Wu as
      compensation for time and efforts made on behalf of the Company  primarily
      with respect to assistance in the  Company's  efforts to raise  additional
      funds to finance operations.

      DR. KWEN-JEN CHANG

      Two scientists related to Dr. Kwen-Jen Chang, Chairman,  President and CEO
      of the  Company,  were  employed  by the  Company  in  2004  and  received
      compensation as follows:

            o     Ms. Jane Chang, his spouse, $53,316 in wages and 20,000 common
                  stock options

            o     Ms.  Jane Hai Xai,  his  niece,  $41,767  in wages and  20,000
                  common stock options

      TIM C. GUPTON

      Tim Gupton, a Director,  is a partner in Hughes,  Pittman, and Gupton. His
      firm received  $6,014 in 2004 as compensation  for tax return  preparation
      and other financial analysis services.  As of the end of 2004, the Company
      will no longer utilize the services of Hughes, Pittman, and Gupton.

      SCARLET KNIGHTS HOLDINGS, LLC

      Scarlet  Knights  Holdings,  LLC, a company owned in part by CCA, of which
      David  LaVance,  a former  Director  of the  Company,  is a  partner,  has
      acquired  120,150  shares  of  Series A  Preferred  Stock of the  Company,
      120,150  shares  of Series B  Preferred  Stock of the  Company,  1,000,000
      shares of Series C Preferred Stock of the Company, and 1,142,857 shares of
      Common Stock of the Company from Elan.

      ELAN

      Prior to 2004, the Company  participated  in two joint ventures with Elan.
      In conjunction therewith, Elan loaned money to and purchased preferred and
      common shares of the Company.  The outstanding  balance on the loan totals
      $1,925,028.  During 2004, the Company  expensed  $236,893 in interest;  at
      December 31, 2004, accrued interest to Elan totaled $457,908.


(8)   COMMITMENTS AND CONTINGENCIES

      LEASES

      The  Company  leases  office and lab space under  noncancelable  operating
      leases.   Future  minimum  annual  lease  payments  under   non-cancelable
      operating leases in effect as of December 31, 2004 are:

                      2005                      $  344,147
                      2006                         348,943
                      2007                         310,536
                      2008                         319,852
                      Thereafter                   329,448
                                                ----------
                                                $1,652,926
                                                ==========

      Rent expense was $368,631 in 2004.

      CONSULTING AGREEMENTS

      In October  2002,  the Company  entered  into an  agreement  with  Century
      Capital  Associates,  whose managing  director is a member of the Board of
      Directors,  to assist in  securing  alternative  financing  and  licensing
      agreements with other pharmaceutical  companies.  Compensation  includes a
      one-time  retainer  fee of $50,000 and fees that are  contingent  upon the
      amount of funding, as defined.

      During 2004,  the Company  entered into an  agreement  with SCO  Financial
      Group to assist in certain  aspects  of  securing  financing  or a merger.
      Compensation  includes  a  one-time  retainer  fee  of  $25,000  and  fees
      (including  cash and warrants)  that are  contingent  upon the  successful
      completion of certain funding or merger events, as defined.

      ROYALTY PAYMENTS

      The Company possesses the exclusive worldwide rights to certain technology
      acquired  from  GlaxoWellcome  (now  known as  GlaxoSmithKline),  and as a
      result may be  obligated  for future  royalty  payments of up to 2% of net
      sales, as defined, for the duration of the related patents.

      LITIGATION

      From time to time,  the Company is a defendant in lawsuits  incidental  to
      the  operation  of its  business.  Management  does not  believe  that any
      pending  legal  proceedings  would have a material  adverse  effect on the
      financial position or results of operations of the Company.

      By letter to the Company,  dated  January 11, 2005,  Organon  asserted its
      belief that it  maintains  certain  rights under the License (see Note 2).
      The Company believes this claim is without merit and has initiated dispute
      resolution procedures specified in the License to confirm that the License
      has been terminated and that Organon has no further rights thereunder.


(8)   COMMITMENTS AND CONTINGENCIES (CONTINUED)

      GOING CONCERN

      As  shown  in the  accompanying  financial  statements,  the  Company  has
      incurred  significant  losses,  has  negative  working  capital  and needs
      additional  capital  to  finance  its  operations.  These  factors  create
      substantial  doubt  about the  Company's  ability to  continue  as a going
      concern.  The  financial  statements do not include any  adjustments  that
      might be  necessary  if the  Company  is  unable  to  continue  as a going
      concern.  The Company  intends to finance its operations  through sales of
      its securities as well as entering into loans and other types of financing
      arrangements such as convertible debenture. There is no assurance that the
      Company will be successful in its efforts.

(9)   SUBSEQUENT EVENTS - MERGER BETWEEN ARDENT AND ENHANCE BIOTECH, INC.

      On December 20, 2004,  the Company  completed a merger whereby it became a
      wholly owned subsidiary of Enhance Biotech Inc.  ("Enhance"),  pursuant to
      the Agreement and Plan of Merger, as amended. For accounting purposes, the
      merger was made effective  December 31, 2004.  Enhance acquires,  develops
      and seeks to commercialize  drugs primarily to treat lifestyle  disorders.
      Enhance's  drug pipeline  consists of eight products and focuses on two of
      the seven  major  segments  in the  lifestyle  drug  market:  male  sexual
      dysfunction  and  dermatology.  Except for  certain  "Excluded  Shares" (a
      certain  warrant to purchase 1.5 million  shares of common stock issued to
      Bioaccelerate,  Inc.,  Enhance's largest  shareholder) and "Contingent Fee
      Shares"  (319,171  shares of Enhance common stock reserved for issuance in
      settlement  of  certain  fee  arrangements  entered  into  with  CCA,  the
      financial  advisor  for  this  transaction),  upon the  conclusion  of the
      merger,  on  a  fully  diluted  basis,   Enhance  shareholders  of  record
      immediately  prior to the  merger  own  approximately  fifty-five  percent
      (55%),  and  the  former  Ardent  securities   holders  own  approximately
      forty-five  percent (45%), of the common stock, par value $0.001 per share
      of Enhance.

      Ardent's  management and Board of Directors  considered a range of factors
      in favor of the merger including:

      o     Favorable merger consideration

      o     Improved access to financing

      o     Access to a credit facility through Bioaccelerate

      o     Significant ownership and role in Enhance's management

      o     Complementary development programs between the two companies

      o     Increased liquidity for Ardent shareholders

      As a result of the  merger,  the  combined  portfolio  of  products  under
      development  between the merged  companies is a substantial  one including
      products in Urology, Dermatology, and the Central Nervous System (CNS).

      The Company  considers  the Urology and  Dermatology  areas to be its core
      areas of focus and  intends  to invest the  majority  of its  capital  and
      attention in these areas.  The Company  intends to invest  modestly in its
      non-core  areas and looks to partner these  compounds at an early stage of
      development.

      On  January 1, 2005,  Bioaccelerate  provided a $2 million  line of credit
      convertible into common stock at the lower of $1.50 per share or the price
      per share of the Company's next  financing from an unrelated  third party.
      The line matures in five years and bears  interest at 3.5%, the equivalent
      Federal  Risk  Free  Rate at the time of  issuance.  The  Company  granted
      Bioaccelerate  750,000  warrants as an inducement to provide the facility.
      The five year $3 warrants immediately vest upon grant.


(9)   SUBSEQUENT  EVENTS - MERGER  BETWEEN  ARDENT  AND  ENHANCE  BIOTECH,  INC.
      (CONTINUED)

      Upon the effective date of the merger,  each  outstanding  share of Ardent
      common and preferred stock,  including preferred dividends,  was cancelled
      automatically and converted into shares of Enhance's Common Stock ("Merger
      Shares").  Also,  Ardent options,  warrants and certain  convertible notes
      which could have been  exercised or converted to receive  shares of Ardent
      common stock,  may be exercised or converted into shares of Enhance Common
      Stock. In addition,  Enhance  reserved for issuance  sufficient  shares to
      cover such exercises or conversions.

      As a consequence,  upon the effectiveness of the merger, in the aggregate,
      the outstanding shares of Ardent common and preferred stock were converted
      into, and the outstanding  Ardent options,  warrants and convertible notes
      became exercisable or convertible to receive,  approximately the following
      number of shares of Enhance Common Stock:

            Ardent Common Stock**                      16,999,116 Shares
            Ardent Options**                            3,964,857 Shares
            Ardent Warrants**                             887,858 Shares
            Ardent Convertible Promissory Notes**         258,584 Shares
            Series A Preferred Stock**                  1,251,139 Shares
            Series B Preferred Stock**                    875,797 Shares
            Series C Preferred Stock**                    801,812 Shares
            Series D 1 Preferred Stock                  1,034,604 Shares
            Series D 2 Preferred Stock                  2,187,340 Shares

      ** Includes  the number of shares of Enhance  common  stock  allotted  for
      Ardent common and preferred  stock holders,  as well as the Contingent Fee
      Shares.

      As a consequence of the effectiveness of the merger,  Ardent  shareholders
      receive  approximately  23,149,808  shares of Enhance,  in the  aggregate.
      Enhance has reserved  approximately  5,111,299 shares in the aggregate for
      issuance upon exercise of outstanding  options,  warrants and  convertible
      promissory notes of Ardent outstanding prior to the merger. As of December
      31, 2004,  approximately  234,172 of the  Contingent  Fee Shares have been
      issued.

      The 23,149,808  Enhance shares issued in conjunction  with the merger were
      valued at approximately $27,263,000,  or approximately $1.18 per share, as
      determined  by  management.  Shares of Enhance  common stock are currently
      traded on the pink sheets with very limited trading volume.

      In conjunction with the merger, Enhance entered into a Registration Rights
      Agreement,  dated December 20, 2004, in which Enhance has agreed to file a
      registration  statement  under the Securities Act to register up to 30,000
      shares of the Enhance  common stock issued to each Ardent  shareholder  as
      soon as  practicable  after a Qualified  Financing,  but in no event later
      than 150 days  following  the  closing  of the  merger and to use its best
      efforts to have that  registration  statement  declared  effective  by the
      Securities and Exchange Commission (SEC).  Enhance also agreed that if the
      common  stock is then listed on a national  stock  exchange,  Enhance will
      file a listing application with such exchange, and use its best efforts to
      have  admitted  to trading  on such  exchange  all shares of common  stock
      issued to Ardent shareholders as merger  consideration that are covered by
      a registration  statement under the Securities Act which has been declared
      effective by the SEC.  Enhance agreed to use its  commercially  reasonable
      best  efforts  to  keep  each  such  registration  statement  continuously
      effective,  subject to customary blackout periods and exceptions,  for one
      year  following  the date upon which each such  registration  statement is
      declared  effective by the SEC (such period to be extended by the duration
      of any such  blackout  period or other  period  in which the  registration
      statement does not continue to be effective).


(9)   SUBSEQUENT  EVENTS - MERGER  BETWEEN  ARDENT  AND  ENHANCE  BIOTECH,  INC.
      (CONTINUED)

      Enhance also agreed to file with the SEC, no later than 180 days after the
      closing of the merger,  a Registration  Statement on Form S-8 covering the
      shares of common stock to be issued upon  exercise of Ardent stock options
      which continue to be outstanding  after the closing of the merger,  and to
      use its best efforts to have such Registration Statement become and remain
      continuously effective under the Securities Act. Enhance agreed to furnish
      corresponding registration rights in respect of the shares of common stock
      underlying warrants or options held by Bioaccelerate. All but 1,500,000 of
      the underlying shares held by Bioaccelerate will continue to be subject to
      a 12-month lock-up notwithstanding registration.

      All  shares of merger  consideration  issued  to  former  Ardent  security
      holders are  "restricted  shares" within the meaning of the Securities Act
      of 1933, as amended (the  "Securities  Act"), and may not be freely traded
      until either covered by an effective registration statement filed with the
      SEC under applicable laws (as well as any corresponding  filings which may
      be required under state or other  securities laws) or disposed of pursuant
      to an available exemption to such registration.  In addition,  each holder
      of 5% or more of  Enhance's  common  stock has  agreed to be  subject to a
      lock-up  period  restricting  transfer  of such  shares for a period of 12
      months  after the  effectiveness  of the merger,  with such lock-up to end
      earlier with  respect to any shares  covered by a  registration  statement
      filed by Enhance pursuant to the Securities Act and declared  effective by
      the SEC.

      Notwithstanding  Enhance's  agreements,  there  can be no  assurance  that
      Enhance will ever file any such  registration  statement  and, even if so,
      that any such registration  statement will ever become effective,  or that
      once effective, such effectiveness will be maintained.

      Ardent and Enhance  incurred fees to legal advisors and agents  associated
      with the merger totaling  $775,000,  plus 234,172 shares of Enhance common
      stock.

      UNAUDITED PRO FORMA FINANCIAL INFORMATION

      The  following  unaudited  pro  forma  condensed  combined  balance  sheet
      aggregates  the  balance  sheet  of  Enhance  Biotech,  Inc.  (a  Delaware
      corporation)  ("PARENT")  as of December 31, 2004 and the balance sheet of
      Ardent Pharmaceutical,  Inc. (a North Carolina corporation) ("SUBSIDIARY")
      as of December 31, 2004,  accounting for the transaction as an acquisition
      of a  SUBSIDIARY  with the  issuance of common stock of the PARENT for all
      the  issued  and  outstanding  shares  of the  SUBSIDIARY  and  using  the
      assumptions  described  in  the  following  notes,  giving  effect  to the
      transaction, as if the transaction had occurred as of the beginning of the
      period.  The  transaction  was completed on December 20, 2004,  though for
      accounting purposes it was made effective December 31, 2004.

      The  following   unaudited  pro  forma  condensed  combined  statement  of
      operations  combines  the results of  operations  of PARENT for the eleven
      months ended December 31, 2004 and the results of operations of SUBSIDIARY
      for the year ended December 31, 2004 as if the transaction had occurred at
      the beginning of the periods.

      The pro forma condensed  combined  financial  statements should be read in
      conjunction  with the  separate  financial  statements  and related  notes
      thereto of PARENT and SUBSIDIARY. These pro forma financial statements are
      not  necessarily  indicative of the combined  financial  position,  or the
      combined  results of  operations  which might have existed for the periods
      indicated or the results of operations as they may be in the future.


(9)   SUBSEQUENT  EVENTS - MERGER  BETWEEN  ARDENT  AND  ENHANCE  BIOTECH,  INC.
      (CONTINUED)

                              ENHANCE BIOTECH, INC
                        AND ARDENT PHARMACEUTICALS, INC.
           UNAUDITED PRO FORMA CONDENSED COMBINED FINANCIAL STATEMENTS
                                December 31, 2004
                      (in thousands, except loss per share)



                                  Enhance            Ardent             Pro forma       Pro forma
                               Biotech, Inc.    Pharmaceutical, Inc     Increase        Combined
                                 [PARENT]         [SUBSIDIARY]         (Decrease)
                                                                              
CONDENSED
BALANCE SHEET
ASSETS
Current assets                  $      391         $      481            $       --       $      872
Patents                                 --                577                24,251[A]        24,828
Property and equipment                  52                755                    --              807
Other long term assets                 749                 11                    --              760
                                ---------------------------------------------------       ----------
TOTAL ASSETS                    $    1,192         $    1,824            $   24,251       $   27,267
                                ===================================================       ==========
LIABILITIES & EQUITY
Current Liabilities             $    3,340         $      938                  $100[B]    $    4,378

Long term liabilities                   --              3,171                    --            3,171
Stockholders' Equity                (2,148)            (2,285)               24,151[C]        19,718
                                ---------------------------------------------------       ----------
TOTAL LIABILITIES & EQUITY      $    1,192         $    1,824            $   24,251       $   27,267
                                ===================================================       ==========
CONDENSED
STATEMENT OF OPERATIONS
Revenues                                --                123                    --              123
Operating costs & expenses          (4,773)            (5,320)                 (100)[B]      (10,193)
Other income (expenses)                  1               (217)                   --             (216)
                                ---------------------------------------------------       ----------
NET LOSS                        $   (4,772)        $   (5,414)           $     (100)      $  (10,286)
                                ===================================================       ==========
                                                                                          $    (0.20)
BASIC AND DILUTED
NET LOSS PER COMMON SHARE
                                                                                          ==========
WEIGHTED AVERAGE                                                                              51,695
SHARES OUTSTANDING                                                                        ==========


      NOTE 1 -PRO FORMA ADJUSTMENTS

      On December 20,  2004,  SUBSIDIARY  was  acquired by PARENT  pursuant to a
      definitive  Merger  Agreement  signed on August 11,  2004.  The  agreement
      called for PARENT to issue up to 23,149,808  shares of common stock to the
      shareholders  of  SUBSIDIARY  for  100%  of  the  outstanding   shares  of
      SUBSIDIARY.  The ownership interests of the former owners of SUBSIDIARY in
      the  combined   enterprise  will  be  approximately  45%  of  the  ongoing
      shareholders of PARENT.

      Pro forma adjustments above include the following:

      [A]   Allocate excess purchase price to patents.
      [B]   Add estimated regulatory compliance costs.
      [C]   Issue  23,149,808  shares  of  common  stock  and  eliminate  equity
            accounts of SUBSIDIARY.

      NOTE 2 - PRO FORMA (LOSS) PER SHARE

      Pro forma  (loss)  per  share is  computed  based on the  number of shares
      outstanding,  as though all merger shares had been issued at the beginning
      of the period.



(b) Pro forma financial information.

    The following unaudited pro forma condensed combined balance sheet
    aggregates the balance sheet of Enhance Biotech, Inc. (a Delaware
    corporation) ("PARENT") as of December 31, 2004 and the balance sheet of
    Ardent Pharmaceutical, Inc. (a North Carolina corporation) ("SUBSIDIARY") as
    of December 31, 2004, accounting for the transaction as an acquisition of a
    SUBSIDIARY with the issuance of common stock of the PARENT for all the
    issued and outstanding shares of the SUBSIDIARY and using the assumptions
    described in the following notes, giving effect to the transaction, as if
    the transaction had occurred as of the beginning of the period. The
    transaction was completed on December 20, 2004, though for accounting
    purposes it was made effective December 31, 2004.

    The following unaudited pro forma condensed combined statement of operations
    combines the results of operations of PARENT for the eleven months ended
    December 31, 2004 and the results of operations of SUBSIDIARY for the year
    ended December 31, 2004 as if the transaction had occurred at the beginning
    of the periods.

    The pro forma condensed combined financial statements should be read in
    conjunction with the separate financial statements and related notes thereto
    of PARENT and SUBSIDIARY. These pro forma financial statements are not
    necessarily indicative of the combined financial position, or the combined
    results of operations which might have existed for the periods indicated or
    the results of operations as they may be in the future.

                              ENHANCE BIOTECH, INC
                        AND ARDENT PHARMACEUTICALS, INC.
           UNAUDITED PRO FORMA CONDENSED COMBINED FINANCIAL STATEMENTS
                                December 31, 2004
                      (in thousands, except loss per share)




                                  Enhance            Ardent             Pro forma       Pro forma
                               Biotech, Inc.    Pharmaceutical, Inc     Increase        Combined
                                 [PARENT]         [SUBSIDIARY]         (Decrease)
                                                                             
CONDENSED
BALANCE SHEET
ASSETS
Current assets                  $      391          $      481          $       --       $      872
Patents                                 --                 577              24,251[A]        24,828
Property and equipment                  52                 755                  --              807
Other long term assets                 749                  11                  --              760
                                --------------------------------------------------       ----------

TOTAL ASSETS                    $    1,192          $    1,824          $   24,251       $   27,267
                                ==================================================       ==========
LIABILITIES & EQUITY
Current Liabilities             $    3,340          $      938                $100[B]    $    4,378

Long term liabilities                   --               3,171                  --            3,171
Stockholders' Equity                (2,148)             (2,285)             24,151[C]        19,718
                                --------------------------------------------------       ----------
TOTAL LIABILITIES & EQUITY      $    1,192          $    1,824          $   24,251       $   27,267
                                ==================================================       ==========
CONDENSED
STATEMENT OF OPERATIONS
Revenues                                --                 123                  --              123
Operating costs & expenses          (4,773)             (5,320)               (100)[B]      (10,193)
Other income (expenses)                  1                (217)                 --             (216)
                                --------------------------------------------------       ----------
NET LOSS                        $   (4,772)         $   (5,414)         $     (100)      $  (10,286)
                                ==================================================       ==========
                                                                                         $    (0.20)
BASIC AND DILUTED
NET LOSS PER COMMON SHARE
                                                                                         ==========
WEIGHTED AVERAGE                                                                             51,695
SHARES OUTSTANDING                                                                       ==========


      NOTE 1 -PRO FORMA ADJUSTMENTS

      On December 20,  2004,  SUBSIDIARY  was  acquired by PARENT  pursuant to a
      definitive  Merger  Agreement  signed on August 11,  2004.  The  agreement
      called for PARENT to issue up to 23,149,808  shares of common stock to the
      shareholders  of  SUBSIDIARY  for  100%  of  the  outstanding   shares  of
      SUBSIDIARY.  The ownership interests of the former owners of SUBSIDIARY in
      the  combined   enterprise  will  be  approximately  45%  of  the  ongoing
      shareholders of PARENT.

      Pro forma adjustments above include the following:

      [A]   Allocate excess purchase price to patents.
      [B]   Add estimated regulatory compliance costs.
      [C]   Issue  23,149,808  shares  of  common  stock  and  eliminate  equity
            accounts of SUBSIDIARY.

      NOTE 2 - PRO FORMA (LOSS) PER SHARE

      Pro forma  (loss)  per  share is  computed  based on the  number of shares
      outstanding,  as though all merger shares had been issued at the beginning
      of the period.


(c) Exhibits.

The following exhibit is filed with this report:

23.1 Consent of Cacciamatta Accountancy Corporation

[Signatures on following page.]



                                   SIGNATURES

Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
Registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.

                                      ENHANCE BIOTECH, INC.
                                      (Registrant)


                                      By:  /s/ Christopher Every
                                      -------------------------
                                      Christopher Every
                                      Chief Executive Officer

Date: March 24, 2005



                                  EXHIBIT INDEX

Exhibit     Description

23.1        Consent of Cacciamatta Accountancy Corporation