UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 23, 2005 CYTOMEDIX, INC. (Exact name of registrant as it appears in its charter) Delaware 000-28443 23-3011702 (State or other jurisdiction (Commission File Number) (IRS Employee of incorporation) Identification No.) 416 Hungerford Drive, Suite 330 Rockville, Maryland 20850 (Address of principal executive offices and zip code) 240-499-2680 (Registrant's telephone number, including area code) Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below): |_| Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) |_| Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) |_| Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) |_| Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) Item 1.01 Entry into a Material Definitive Agreement Cytomedix, Inc. has agreed to settle its patent infringement lawsuit against Harvest Technologies Corporation, which was filed on October 23, 2003 in the U.S. District Court for the District of Massachusetts, Civil Action No. 02-12077. In connection with the settlement, Cytomedix entered into a license agreement with Harvest under which Cytomedix will receive: (1) a lump sum payment of $500,000 on the later of (a) June 28, 2005 and (b) the first business day after the entry of the order dismissing with prejudice the patent infringement lawsuit; and (2) beginning on June 30, 2005, will receive a 1.5% royalty on all of the net sales of hardware products sold by Harvest and a 7.5% royalty on disposable products sold by Harvest. Cytomedix issued the attached press release announcing that it had agreed to settle the patent dispute and had entered into a license agreement. The press release is filed as Exhibit 99.1 and incorporated herein by reference. Attached hereto as Exhibit 99.2 and incorporated herein by reference is the Settlement and License Agreement between Cytomedix and Harvest, dated May 23, 2005. Item 8.01 Other Events On May 26, 2005, Cytomedix received notice that the American Stock Exchange has approved the company's application for the listing of its common stock. This approval is contingent upon Cytomedix being in compliance with all applicable listing standards on the date it begins trading on the American Stock Exchange, and may be rescinded if Cytomedix is not in compliance with such standards. Cytomedix issued the attached press release announcing that its listing application had been approved. The press release is filed as Exhibit 99.3 and incorporated herein by reference. Item 9.01. Financial Statements and Exhibits (c) Exhibits See Exhibit Index attached hereto. SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized. CYTOMEDIX, INC. By: /s/ Kshitij Mohan ---------------------- Kshitij Mohan Chief Executive Officer Date: May 27, 2005 EXHIBIT INDEX Exhibit No. Description - ----------- ----------- 99.1 Press Release, dated May 24, 2005 99.2+ Settlement and License Agreement between Cytomedix and Harvest Technologies, Inc., dated May 23, 2005. 99.3 Press Release, dated May 26, 2005 + Confidential Treatment requested as to certain portions, which portions have been separately filed with the Securities and Exchange Commission.