EXIBIT 32.1: CERTIFICATION OF PRINCIPAL EXECUTIVE OFFICER AND PRINCIPAL
FINANCIAL OFFICER PURSUANT TO 18 U.S.C. 1350, as adopted pursuant to Section 906
of the Sarbanes-Oxley Act of 2002.*

      In connection with the accompanying Quarterly Report on Form 10-QSB of
SyntheMed, Inc. for the quarter ended June 30, 2005, the undersigned hereby
certifies pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906
of the Sarbanes-Oxley Act of 2002, to the best of my knowledge and belief, that:

            (1)   such Quarterly Report on Form 10-QSB for the quarter ended
                  June 30, 2005 fully complies with the requirements of Section
                  13(a) or 15(d) of the Securities Exchange Act of 1934; and

            (2)   the information contained in such Quarterly Report on Form
                  10-QSB for the quarter ended June 30, 2005 fairly presents, in
                  all material respects, the financial condition and results of
                  operations of SyntheMed, Inc.

      July 26, 2005                           /s/ Robert P. Hickey
                                              --------------------
                                              Name: Robert P. Hickey
                                              Title: Chief Executive Officer
                                                     and Chief Financial Officer

* A signed original of this written statement required by Section 906, or other
document authenticating, acknowledging or otherwise adopting the signature that
appears in typed form within the electronic version of this written statement
required by Section 906, has been provided by SyntheMed, Inc. and will be
retained by SyntheMed, Inc. and furnished to the Securities and Exchange
Commission or its staff upon request.


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