Brainstorm Cell Therapeutics Inc.


                INVESTOR QUESTIONNAIRE AND SUBSCRIPTION AGREEMENT

THE  SECURITIES  REFERRED TO IN THIS  INVESTOR  QUESTIONNAIRE  AND  SUBSCRIPTION
AGREEMENT HAVE NOT BEEN REGISTERED  UNDER THE SECURITIES ACT OF 1933, AS AMENDED
(THE  "SECURITIES  ACT"),  NOR HAVE THEY BEEN REGISTERED WITH OR APPROVED BY THE
SECURITIES  REGULATORY  AUTHORITY OF ANY STATE,  AND SUCH  SECURITIES MAY NOT BE
SOLD  OR  OTHERWISE  TRANSFERRED  OR  ASSIGNED  UNLESS  THERE  IS  AN  EFFECTIVE
REGISTRATION  STATEMENT  UNDER  THE  SECURITIES  ACT  AND ANY  APPLICABLE  STATE
SECURITIES LAWS COVERING SUCH SECURITIES OR PURSUANT TO AN EXEMPTION THEREFROM.

TO:  Brainstorm Cell Therapeutics Inc.
     1350 Avenue of the Americas, New York NY 10019
     Attn: Dr. Yaffa Beck

      The  undersigned  hereby  subscribes for units (the "Units") each of which
consists  of (a) a share of Common  Stock,  par value  $0.00005  per share  (the
"Common  Shares"),  in Brainstorm  Cell  Therapeutics  Inc., a Washington  State
company  (the  "Company")  and (b) a warrant to purchase one Common Share of the
Company for $1.00 per Common Share  exercisable for three years from the date of
issuance. The Company has requested that the undersigned provide the information
set  forth  in this  Investor  Questionnaire  and  Subscription  Agreement.  The
undersigned represents and warrants to the Company as follows:

      1.  Residence.  The undersigned is a bona fide resident and domiciliary of
the state  designated on the signature page hereof as his or her residence,  and
has no  present  intention  of  becoming  a  resident  of  any  other  state  or
jurisdiction.

      2.  Investment  Intent.  The undersigned is acquiring the Units solely for
his, her or its own account for investment  and not with a view to  distribution
or resale.  The  undersigned  will not sell,  hypothecate,  pledge or  otherwise
dispose  of the  Units in  whole  or in part  except  pursuant  to an  effective
registration  statement  under  the  Securities  Act  and any  applicable  state
securities laws or an exemption from the registration requirements thereof.

      3. Knowledge and Experience.  The undersigned has sufficient knowledge and
experience  in business  and  financial  matters to evaluate  the  Company,  its
proposed activities and the risks and merits of this investment. The undersigned
is  generally  knowledgeable  about the  Company's  business and able to make an
informed decision regarding an investment in the Company's securities.

      4. Limited Market for Units. The undersigned understands that the issuance
of the Units has not been registered under the Securities Act and that the Units
are being sold in reliance upon the exemption from the registration requirements
under the  Securities  Act provided in  Regulation  D. The  undersigned  further
understands  that  there is a limited  public  trading  market for the Units and
notwithstanding the Company's reasonable best efforts as contemplated by Section
15 below  there can be no  assurance  that the  registration  of the Units  will
become  effective  or  that an  active  market  will  develop.  The  undersigned
acknowledges  that  the  purchase  of  the  Units  is a  speculative  investment
involving a high degree of risk and any estimates and predictions  that may have
been made by the Company merely  represent  predictions of future events,  which
may or may not occur and are based on  assumptions,  which may or may not occur.
As a consequence, such predictions may not be relied upon to indicate the actual
results, which might be attained.  The undersigned  understands that he/she must
therefore bear the economic risk of this investment for an indefinite  period of
time and be able to withstand a total loss of its investment.

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      5. Economic Ability. The undersigned is able (a) to bear the economic risk
of an investment in the Units, (b) to hold the Units for an indefinite period of
time and (c) to afford a complete loss of such investment, if this should occur.
If an individual, the undersigned has adequate means of providing for his or her
current needs and personal or family contingencies.  The undersigned has no need
for liquidity in the investment in the Units.

      6. Access to Documents. The undersigned has carefully reviewed the Private
Placement Memorandum dated as of August 11, 2005 that relates to the sale of the
Units (the "PPM") and the  Company's  filings with the  Securities  and Exchange
Commission,  including,  without limitation, the Company's Annual Report of Form
10-KSB for the year ended March 31, 2005, Proxy Statement on Schedule 14A, dated
February 28, 2005,  Quarterly  Report on Form 10-QSB for the quarter ending June
30,  2005,  and  Current  Reports  on  Form  8-K for the  past  12  months  (the
"Securities Filings"),  is familiar with them, and understands and has evaluated
the risks of a purchase of the Units. Such risks are set forth in the PPM and in
the 10-QSB for the Quarterly Period ended June 30, 2005 entitled "Risk Factors".

      7.  Access to Other  Information.  In making a decision  to  purchase  the
Units,  the  undersigned  has relied  solely  upon his,  her or its  independent
investigation.  The  undersigned has had the opportunity to ask questions of and
receive  answers from the Company (or persons  acting on its behalf)  concerning
the terms and conditions of the Units,  the proposed  activities of the Company,
and other matters  pertaining to this  investment  and to obtain any  additional
information  which the Company  possesses  or can acquire  without  unreasonable
effort or expense  that is  necessary  to verify  the  accuracy  of  information
furnished by the Company in the  Securities  Filings or that which was otherwise
provided in order for the  undersigned  to  evaluate  the merits and risks of an
investment  in the  Units,  and  has  not  been  furnished  any  other  offering
literature or prospectus.  All such questions and requests for information  have
been answered to the full satisfaction of the undersigned.

      8. Independent Advisors.  The undersigned has been advised to consult with
an independent  attorney  regarding legal matters  concerning the Company and to
consult  with an  independent  tax adviser  regarding  the tax  consequences  of
purchasing the Units.

      9. Accredited Status. The undersigned hereby represents that he, she or it
is an "accredited investor" as such term is defined in Rule 501(a) of Regulation
D promulgated  under the Securities Act for one or more of the reasons specified
below. Please check each box that applies:

|_|   The  undersigned is an individual  with a net worth (or net worth with his
      or her spouse) in excess of $1 million.

|_|   The undersigned is an individual  with net income  (without  including any
      net income of the  undersigned's  spouse) in excess of $200,000,  or joint
      income with the undersigned's  spouse,  in excess of $300,000,  in each of
      the two most recent years, and the undersigned reasonably expects to reach
      the same income level in the current year.

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|_|   The  undersigned is a bank as defined in the Securities Act, a savings and
      loan association,  or other institution described in section 3(a)(5)(A) of
      the Securities Act acting in either its individual or fiduciary  capacity.
      This includes a trust for which a bank acts as trustee.

|_|   The undersigned is a director,  executive  officer,  general  partner,  or
      manager  of  the  Company  or any  director,  executive  officer,  general
      partner, or manager of a general partner or manager of the Company.

|_|   The  undersigned  is a trust  not  formed  for  the  specific  purpose  of
      acquiring the Units with total assets in excess of $5,000,000 and directed
      by a  person  who has such  knowledge  and  experience  in  financial  and
      business  matters as to be capable of  evaluating  the merits and risks of
      investing in the Company.

|_|   The undersigned is a revocable  trust  (including a revocable trust formed
      for the specific purpose of acquiring the Units and the grantor or settlor
      of such trust is an "accredited investor".

|_|   The  undersigned is an entity in which each equity owner is an "accredited
      investor."

|_|   The  undersigned  is  a  tax-exempt   organization  described  in  Section
      501(c)(3) of the Internal  Revenue  Code, a  corporation,  a Washington or
      similar business trust, a partnership or a limited  liability  company not
      formed for the specific  purpose of acquiring  Units that has total assets
      in excess of $5,000,000.

|_|   The  undersigned is a plan for the benefit of employees,  established  and
      maintained  by a  state,  its  political  subdivisions,  or an  agency  or
      instrumentality  of a state or its  political  subdivisions,  having total
      assets in excess of $5,000,000.

|_|   The  undersigned  is an  employee  benefit  plan within the meaning of the
      Employee Retirement Income Security Act of 1974, as amended, (a) for which
      the investment decision to acquire Units is being made by a plan fiduciary
      that is either a bank, savings and loan association, insurance company, or
      registered  investment  adviser,  (b) which has total  assets in excess of
      $5,000,000,  or (c)  which is  participant-directed  with  the  investment
      decisions made solely by persons who are "accredited investors."

|_|   The  undersigned  is a broker or dealer  registered  under the  Securities
      Exchange Act of 1934, as amended.

|_|   The undersigned is an insurance company as defined in the Securities Act.

|_|   The undersigned is an investment  company  registered under, or a business
      development  company as defined in, the Investment Company Act of 1940, as
      amended.

|_|   The  undersigned is a Small Business  Investment  Company  licensed by the
      U.S. Small Business Administration.

|_|   The undersigned is a private  business  development  company as defined in
      the Investment Advisers Act of 1940, as amended.

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|_|   The undersigned  cannot make any of the  representations  set forth in the
      above paragraphs.

      10. Finder's Fees. The  undersigned  has made no arrangement,  which could
give rise to any broker's or finder's  fees or similar fees in  connection  with
the purchase of the Units.  The  undersigned  acknowledges  that the Company has
retained and will compensate  Octagon Trading Group, LLC as a placement agent in
connection with the sale of the Units.

      11. Place of Investment.  The undersigned  acknowledges that the offer and
sale of the Units,  and the  undersigned's  decision to subscribe for the Units,
was made in state indicated on the signature page hereof.

      12.  Escrow.  The  undersigned  acknowledges  that (a)  funds  sent by the
undersigned to the above address will be held in a  non-interest  bearing escrow
account by an escrow agent to be selected by the Company  (the  "Escrow  Agent")
pending the closing of the offering of the Units, which closing is solely at the
Company's  discretion,  and (b) if the undersigned's  subscription (or a portion
thereof) is  rejected  by the  Company,  the  undersigned  will be entitled to a
refund of such funds (or such portion thereof),  without interest.  Escrow Agent
shall have no liability or obligation  with respect to the escrowed funds except
for Escrow Agent's willful misconduct or gross negligence, and in no event shall
Escrow Agent be liable for incidental,  indirect,  special, and consequential or
punitive damages.

      13. Indemnification. The undersigned agrees to fully indemnify, defend and
hold harmless the Company,  its management,  directors,  advisers,  consultants,
representatives,   and  each  of  their   affiliates,   employees   and   agents
("Indemnified  Parties")  from any and all  claims,  actions,  causes of action,
losses,  costs and expenses  (including  reasonable  attorneys  fees,  costs and
expenses)  whatsoever  ("Claims")  which may result  from a breach or an alleged
breach of the representations,  warranties and acknowledgments  contained herein
and to further  indemnify,  defend and hold  harmless  the Escrow  Agent and its
Indemnified  Parties against any and all claims which may result from the Escrow
Agent's performance under the escrow agreement as contemplated herein; provided,
however,  that no  Indemnified  Party  shall  have the  right to be  indemnified
hereunder for liability finally determined by a court of competent jurisdiction,
subject to no further appeal,  to have resulted solely from the gross negligence
or willful misconduct of such Indemnified Party.

      14. No Aggregate Minimum Subscription Amount. The undersigned acknowledges
that the Company may close on its  subscription  without  having  received other
subscriptions  pursuant to the Offering  (i.e.  no aggregate  minimum  amount is
required to have been subscribed for in the Offering in order for the Company to
close on any single subscription).

      15. Subsequent  Offering;  Demand Registration Rights. The Company intends
to initiate a  significantly  larger  offering to raise  $9,000,000  via sale of
units comprising Common Shares and warrants for Common Shares promptly following
the closing of this Offering (the "Subsequent  Offering").  The precise terms of
the Subsequent Offering will be determined by the Company. The Company will file
a Registration  Statement on Form SB-2 (or an alternative  available form if the
Company is not eligible to file a Form SB-2)  covering the Common  Shares issued
as part of the Units and into which the warrants are  exercisable  no later than
forty five (45) days after the final closing under the  Subsequent  Offering and
will use its reasonable best efforts to cause such Registration  Statement to be
declared  effective within one hundred and twenty (120) days thereafter.  In the
event the Registration Statement has not been declared effective within 165 days
of the closing of the  Subsequent  Offering (or, if the  Subsequent  Offering is
ultimately not  consummated,  within 285 days of the Closing of this  Offering),
the Company shall pay to the Investors  liquidated  damages equal to 1.0% of the
amount  invested  for each  subsequent  30-day  period  until such  Registration
Statement is declared effective.

                     [End of Text. Signature page follows.]

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                        Brainstorm Cell Therapeutics Inc.


                INVESTOR QUESTIONNAIRE AND SUBSCRIPTION AGREEMENT
                                 SIGNATURE PAGE

The representations  and warranties set forth herein,  including the information
set forth on this  signature  page,  are true and accurate as of the date hereof
and shall be true and accurate as of the date of issuance of the Units and shall
survive such date. If in any respect such  representations  and warranties shall
not be true and accurate prior to issuance of the Units,  the undersigned  shall
give  immediate   notice  of  such  fact  to  the  Company,   specifying   which
representations  and  warranties  are not  true  and  accurate  and the  reasons
therefor.

LEGAL NAME OF INVESTOR:
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Business Address:
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Telephone Number:             (      )
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Fax Number:                   (      )
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Residence Address:
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Telephone Number:             (      )
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Fax Number:                   (      )
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Social Security Number:
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Securities Subscribed for:

      Number of Units: _______________ at $0.80 per Unit

      IN  WITNESS   WHEREOF,   the   undersigned   has  executed  this  Investor
Questionnaire and Subscription Agreement this ___ day of August, 2005.


                                             By:
                                                --------------------------------
                                                Name:



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                                   ACCEPTANCE

      The  foregoing   subscription  is  hereby  accepted  upon  the  terms  and
conditions set forth herein.

                                             Brainstorm Cell Therapeutics Inc.

                                             By:
                                                --------------------------------
                                             Name:
                                             Title:






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