EXIBIT  32.1:   CERTIFICATION  OF  PRINCIPAL  EXECUTIVE  OFFICER  AND  PRINCIPAL
FINANCIAL OFFICER PURSUANT TO 18 U.S.C. 1350, AS ADOPTED PURSUANT TO SECTION 906
OF THE SARBANNES-OXLEY ACT OF 2002.*

      In connection  with the  accompanying  Quarterly  Report on Form 10-QSB of
SyntheMed, Inc. for the quarter ended September 30, 2005, the undersigned hereby
certifies pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906
of the Sarbane-Oxley Act of 2002, to the best of my knowledge and belief, that:

      (1)   such Quarterly Report on Form 10-QSB for the quarter ended September
            30, 2005 fully  complies with the  requirements  of Section 13(a) or
            15(d) of the Securities Exchange Act of 1934; and

      (2)   the  information  contained in such Quarterly  Report on Form 10-QSB
            for the quarter  ended  September 30, 2005 fairly  presents,  in all
            material respects, the financial condition and results of operations
            of SyntheMed, Inc.


October 31, 2005      /s/ Robert P. Hickey
                      ----------------------
                      Name: Robert P. Hickey
                      Title: Chief Executive Officer and Chief Financial Officer

* A signed original of this written statement  required by Section 906, or other
document authenticating,  acknowledging or otherwise adopting the signature that
appears in typed form within the  electronic  version of this written  statement
required by Section  906,  has been  provided  by  SyntheMed,  Inc.  and will be
retained by  SyntheMed,  Inc.  and  furnished  to the  Securities  and  Exchange
Commission or its staff upon request.


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