January 17, 2006

Securities and Exchange Commission
100 F Street, N.E.
Washington, DC  20549

Ladies and Gentlemen:

We have  read  Item  4.01  of Form  8-K  dated  January  17,  2006,  of  Polydex
Pharmaceuticals  Limited and are in agreement with the  statements  contained in
paragraph  (a)  therein.  We have no  basis  to agree  or  disagree  with  other
statements of the registrant contained in paragraph (b) therein.

/s/  Sloan Partners LLP

Sloan Partners LLP