Safetek International Inc.
Oriens Life Sciences Ltd.
 23 Aminadav St.
Tel Aviv, Israel,                                                        |logo|
67898
Tel: +972-3-5613468
Fax: +972-3-5613465
Email:
Info@oriensls.com
www.oriensls.com


                                                                  February 5, 06

       Re: SERVICE ON THE BOARD OF DIRECTORS OF SAFETEK INTERNATIONAL INC.
           ---------------------------------------------------------------

Dear Prof. Koltin,

I am pleased to write to you and request your consent to serve as member of the
Board of Directors of SafeTek International Inc. (respectively, the "BOARD" and
the "COMPANY"), subject to the following terms and conditions:

1.    While serving as member of the Board, you shall act pursuant to any
      applicable law. Your agreement to serve as member of the Board is
      conditioned, among others, upon your agreement not to directly or
      indirectly use or disclose any confidential non-public information of the
      Company for any reason, including, without limitation, in connection with
      the purchase or sale of the securities of the Company. Any such use or
      disclosure would constitute a violation of securities laws.

2.    As a director of the Company, you are expected to maintain loyalty to the
      Company and to not take any action that would directly or indirectly
      promote any competitor or impair the Company's interests. Subject to the
      foregoing, you may engage in other business or charitable activities to
      the extent that they do not interfere or create a conflict with your
      fiduciary obligations to the Company.

3.    Specifically, but not exclusively, your duties and responsibilities will
      include the following: (i) to participate in all meetings of the Board and
      stockholders of the Company; (ii) to serve on such committees of the Board
      as required by the Company; (iii) to provide strategic guidance and advice
      to the senior management of the Company with respect to the management of
      the operations of the Company; and (iv) to provide support and guidance to
      the senior management of the Company in their efforts.

4.    In consideration for your service as a member of the Board, the Company
      shall pay you an amount of US$ 400 for each meeting of the Board or any
      committee thereof in which you participate. The fee increases to $500 if
      the aggregate investment exceeds $3,000,000 after said date.



5.    In addition, and subject to the execution of an option grant agreement
      between you and the Company in a standard form used by the Company (the
      "OPTION AGREEMENT"), you shall be entitled to participate in the Employee
      Stock Option Plan adopted by the Company (the "ESOP"), under the following
      terms and conditions:

6.    You shall receive options to purchase 451,041 shares of Common Stock of
      the Company, par value US$ 0.0001 each, at an exercise price per share
      equal to 90% of the last transaction price quoted for such date by the
      NASDAQ system or the NASDAQ National Market, as of the Stock Option
      Agreement date, according to the company Employees/Consultants/Directors
      Stock Compensation Plan; (the "Options").

7.    The vesting period of the Options will commence from the second year and
      will be in 12 equal quarterly installments of the Common Stock to which
      the Options pertain over a period of 36 months, on the last date of each
      calendar quarter from and after the first anniversary year from the
      agreement date and so long as you hold such office. If your service as
      member of the Board terminates prior to the full vesting of the Options,
      for any reason whatsoever, the unvested portion of the Options shall be
      cancelled. Vested Options will be exercisable for a period of 3 months
      after termination of this Agreement.

8.    For the avoidance of doubt, the terms set forth in this Section are in
      addition to terms and conditions set forth in the ESOP and in the Option
      Agreement as determined by the Board, in its sole discretion, and the
      grant of the Options shall be subject to your execution of the Option
      Agreement and all ancillary documents.

9.    In special cases, and subject to the execution of a consulting agreement
      between you and the Company in the form attached as EXHIBIT A hereto (the
      "CONSULTING AGREEMENT") and all ancillary documents thereof, the Company
      may ask you for additional consulting services. Such services will be
      provided by you pursuant to the terms of the Consulting Agreement and
      against the compensation detailed therein.

10.   During the term of your service and thereafter, and subject to the
      execution of an indemnification agreement between you and the Company in
      the form attached as EXHIBIT B hereto (the "INDEMNIFICATION AGREEMENT")
      and all ancillary documents thereof, the Company shall indemnify you to
      the full extent permitted by law and the incorporation documents of the
      Company for all expenses, costs, liabilities and legal fees which you may
      incur in the discharge of your duties hereunder, all pending your
      execution of the Indemnification Agreement and subject to all terms and
      conditions set forth therein.




Please indicate your acceptance to the terms of this letter by signing and
dating it and returning a counterpart hereof to us.

Note that your appointment as member of the Board of Directors of the Company is
subject to the approval of the Company's directors and/or shareholders.


                                            Sincerely yours,


                                            /s/ Amnon Presler
                                            Amnon Presler, CEO

                                            Phone: 03-5613468
                                            Mobile: 054-7353561






I agree to all terms of this letter.

Sig:  /s/ Yigal Kolton

Name: Prof. Yigal Kolton
Date: February 5, 2006