EXHIBIT 32.1


                CERTIFICATION PURSUANT TO 18 U.S.C. SECTION 1350,
      AS ADOPTED PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

In connection with the Quarterly Report of m-Wise, Inc. ("the Company") on Form
10-QSB for the period ended March 31, 2006 as filed with the Securities and
Exchange Commission on the date hereof ("the Report"), I, Shay Ben-Asulin,
Chairman of the Board and Secretary, certify, pursuant to 18 U.S.C. Section
1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, that
to my knowledge:

      (1) the Report fully comply with the requirements of Section 13(a) or
15(d) of the Securities Exchange Act of 1934; and

      (2) the information contained in the Report fairly presents, in all
material respects, the financial condition and result of operations of the
Company.

By: /s/Shay Ben-Asulin
- ----------------------
Shay Ben-Asulin, Chairman

Dated: May 15, 2006





                                       12