SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

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                                    FORM 8-K

                                 CURRENT REPORT

                     PURSUANT TO SECTION 13 OR 15(D) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

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                        Date of Report: SEPTEMBER 12, 2006

                        MEDICAL STAFFING SOLUTIONS, INC.
               (Exact Name of Registrant as Specified in Charter)

           NEVADA                     000-23967                 91-2135006
           ------                     ---------                 ----------
(State or other jurisdiction         (Commission               (IRS Employer
    of incorporation)                File Number)           Identification No.)

 8150 LEESBURG PIKE, SUITE 1200, VIENNA, VIRGINIA                  22182
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     (Address of principal executive offices)                   (Zip code)

Registrant's telephone number, including area code:           (703) 641-8890





ITEM 8.01.  OTHER EVENTS.


      On September 12, 2006,  Medical Staffing  Solutions,  Inc. (the "Company")
issued a Press  Release  announcing  that it had entered into a Letter of Intent
with General  Healthcare  Resources,  Inc. (the  "Purchaser")  and Nurses Onsite
Corp.,  a  wholly-owned  subsidiary of the Company  ("NOC") on September 6, 2006
pursuant  to which the  Purchaser  would,  directly  or  through an entity to be
organized by the Purchaser,  acquire  substantially all of the assets of NOC for
an aggregate purchase price equal to $2,850,000.  This transaction is subject to
the satisfactory  completion of due diligence and other  conditions,  including,
without  limitation,  the  execution of a definitive  agreement.  A copy of this
Press Release is attached hereto as Exhibit 99.1.

9.01. FINANCIAL STATEMENTS AND EXHIBITS.


(a) Not applicable.

(b) Not applicable.

(c) Not applicable.

(c) Exhibit No. Description:


EXHIBIT           DESCRIPTION

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Exhibit 99.1      Press Release, dated September 12, 2006      Provided herewith
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                                   SIGNATURES

      Pursuant to the  requirements  of the Securities  Exchange Act of 1934, as
amended,  the  Company has duly caused this report to be signed on its behalf by
the undersigned hereunto duly authorized.

                                         MEDICAL STAFFING SOLUTIONS, INC.

Date:    September 12, 2006              By: /s/ Dr. Brajnandan B. Sahay
                                             ------------------------------
                                         Name:   Dr. Brajnandan B. Sahay
                                         Title:  President