SECURITIES & EXCHANGE COMMISSION
                             Washington, D.C. 20549
                             ----------------------

                                  SCHEDULE 13D

                   UNDER THE SECURITIES EXCHANGE ACT OF 1934
                               (AMENDMENT NO. 10)



                            Synageva BioPharma Corp.
                                (Name of Issuer)

                    Common Stock, $.001 Par Value Per Share
                         (Title of Class of Securities)


                                   87159A103
                                 (CUSIP Number)


                           HealthCor Management, L.P.
                              Carnegie Hall Tower
                        152 West 57th Street, 47th Floor
                            New York, New York 10019
                         Attention: Mr. John H. Coghlin
                                 (212) 622-7871
                 (Name, Address and Telephone Number of Person
               Authorized to Receive Notices and Communications)


                                November 3, 2011
            (Date of Event Which Requires Filing of this Statement)


      If  the  filing person has previously filed a statement on Schedule 13G to
report  the  acquisition that is the subject of this Schedule 13D, and is filing
this  schedule  because  of  Rule  13d-1(e),  13d-1(f)  or  13d-1(g),  check the
following box. [ ]

      NOTE:  Schedules filed in paper format shall include a signed original and
five  copies  of  the schedule, including all exhibits. See Rule 13d-7 for other
parties to whom copies are to be sent.

                         (Continued on following pages)


                              (Page 1 of 16 Pages)





CUSIP No. 87159A103                13D/A                Page 2 of 16 Pages

-----------------------------------------------------------------------------
     (1)    NAMES OF REPORTING PERSONS

            HealthCor Management, L.P.

-----------------------------------------------------------------------------
     (2)    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
                                           (see instructions)
                                                                  (a)  [X]
                                                                  (b)  [ ]
-----------------------------------------------------------------------------
     (3)    SEC USE ONLY
-----------------------------------------------------------------------------
     (4)    SOURCE OF FUNDS
            WC
-----------------------------------------------------------------------------
     (5)    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS
            REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)                    [ ]
-----------------------------------------------------------------------------
     (6)    CITIZENSHIP OR PLACE OF ORGANIZATION
            Delaware
-----------------------------------------------------------------------------
NUMBER OF      (7)  SOLE VOTING POWER
                    0

SHARES         --------------------------------------------------------------

BENEFICIALLY   (8)  SHARED VOTING POWER
                    882,731
OWNED BY       --------------------------------------------------------------

EACH           (9)  SOLE DISPOSITIVE POWER
                    0
REPORTING      --------------------------------------------------------------

PERSON WITH    (10) SHARED DISPOSITIVE POWER
                    882,731
-----------------------------------------------------------------------------
     (11)   AGGREGATE AMOUNT BENEFICIALLY OWNED
            BY EACH REPORTING PERSON
            882,731
-----------------------------------------------------------------------------
     (12)   CHECK BOX IF THE AGGREGATE AMOUNT
            IN ROW (11) EXCLUDES CERTAIN SHARES(see instructions)      [ ]
-----------------------------------------------------------------------------
     (13)   PERCENT OF CLASS REPRESENTED
            BY AMOUNT IN ROW (11)
            5.05%
-----------------------------------------------------------------------------
     (14)   TYPE OF REPORTING PERSON (see instructions)
            PN
-----------------------------------------------------------------------------





CUSIP No. 87159A103                13D/A                Page 3 of 16 Pages

-----------------------------------------------------------------------------
     (1)    NAMES OF REPORTING PERSONS

            HealthCor Associates, LLC

-----------------------------------------------------------------------------
     (2)    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
                                              (see instructions)
                                                                  (a)  [X]
                                                                  (b)  [ ]
-----------------------------------------------------------------------------
     (3)    SEC USE ONLY
-----------------------------------------------------------------------------
     (4)    SOURCE OF FUNDS
            AF
-----------------------------------------------------------------------------
     (5)    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS
            REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)                    [ ]
-----------------------------------------------------------------------------
     (6)    CITIZENSHIP OR PLACE OF ORGANIZATION
            Delaware
-----------------------------------------------------------------------------
NUMBER OF      (7)  SOLE VOTING POWER
                    0

SHARES         --------------------------------------------------------------

BENEFICIALLY   (8)  SHARED VOTING POWER
                    882,731
OWNED BY       --------------------------------------------------------------

EACH           (9)  SOLE DISPOSITIVE POWER
                    0
REPORTING      --------------------------------------------------------------

PERSON WITH    (10) SHARED DISPOSITIVE POWER
                    882,731
-----------------------------------------------------------------------------
     (11)   AGGREGATE AMOUNT BENEFICIALLY OWNED
            BY EACH REPORTING PERSON
            882,731
-----------------------------------------------------------------------------
     (12)   CHECK BOX IF THE AGGREGATE AMOUNT
            IN ROW (11) EXCLUDES CERTAIN SHARES(see instructions)      [ ]
-----------------------------------------------------------------------------
     (13)   PERCENT OF CLASS REPRESENTED
            BY AMOUNT IN ROW (11)
            5.05%
-----------------------------------------------------------------------------
     (14)   TYPE OF REPORTING PERSON (see instructions)
            OO - limited liability company
-----------------------------------------------------------------------------





CUSIP No. 87159A103                13D/A                Page 4 of 16 Pages

-----------------------------------------------------------------------------
     (1)    NAMES OF REPORTING PERSONS

            HealthCor Offshore Master Fund, L.P.

-----------------------------------------------------------------------------
     (2)    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP(see instructions)
                                                                  (a)  [X]
                                                                  (b)  [ ]
-----------------------------------------------------------------------------
     (3)    SEC USE ONLY
-----------------------------------------------------------------------------
     (4)    SOURCE OF FUNDS
            AF
-----------------------------------------------------------------------------
     (5)    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS
            REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)                    [ ]
-----------------------------------------------------------------------------
     (6)    CITIZENSHIP OR PLACE OF ORGANIZATION
            Cayman Islands
-----------------------------------------------------------------------------
NUMBER OF      (7)  SOLE VOTING POWER
                    0

SHARES         --------------------------------------------------------------

BENEFICIALLY   (8)  SHARED VOTING POWER
                    577,065
OWNED BY       --------------------------------------------------------------

EACH           (9)  SOLE DISPOSITIVE POWER
                    0
REPORTING      --------------------------------------------------------------

PERSON WITH    (10) SHARED DISPOSITIVE POWER
                    577,065
-----------------------------------------------------------------------------
     (11)   AGGREGATE AMOUNT BENEFICIALLY OWNED
            BY EACH REPORTING PERSON
            577,065
-----------------------------------------------------------------------------
     (12)   CHECK BOX IF THE AGGREGATE AMOUNT
            IN ROW (11) EXCLUDES CERTAIN SHARES (see instructions)     [ ]
-----------------------------------------------------------------------------
     (13)   PERCENT OF CLASS REPRESENTED
            BY AMOUNT IN ROW (11)
            3.30%
-----------------------------------------------------------------------------
     (14)   TYPE OF REPORTING PERSON (see instructions)
            PN
-----------------------------------------------------------------------------





CUSIP No. 87159A103                13D/A                Page 5 of 16 Pages

-----------------------------------------------------------------------------
     (1)    NAMES OF REPORTING PERSONS

            HealthCor Offshore GP, LLC

-----------------------------------------------------------------------------
     (2)    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP(see instructions)
                                                                  (a)  [X]
                                                                  (b)  [ ]
-----------------------------------------------------------------------------
     (3)    SEC USE ONLY
-----------------------------------------------------------------------------
     (4)    SOURCE OF FUNDS
            AF
-----------------------------------------------------------------------------
     (5)    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS
            REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)                    [ ]
-----------------------------------------------------------------------------
     (6)    CITIZENSHIP OR PLACE OF ORGANIZATION
            Cayman Islands
-----------------------------------------------------------------------------
NUMBER OF      (7)  SOLE VOTING POWER
                    0

SHARES         --------------------------------------------------------------

BENEFICIALLY   (8)  SHARED VOTING POWER
                    577,065
OWNED BY       --------------------------------------------------------------

EACH           (9)  SOLE DISPOSITIVE POWER
                    0
REPORTING      --------------------------------------------------------------

PERSON WITH    (10) SHARED DISPOSITIVE POWER
                    577,065
-----------------------------------------------------------------------------
     (11)   AGGREGATE AMOUNT BENEFICIALLY OWNED
            BY EACH REPORTING PERSON
            577,065
-----------------------------------------------------------------------------
     (12)   CHECK BOX IF THE AGGREGATE AMOUNT
            IN ROW (11) EXCLUDES CERTAIN SHARES (see instructions)     [ ]
-----------------------------------------------------------------------------
     (13)   PERCENT OF CLASS REPRESENTED
            BY AMOUNT IN ROW (11)
            3.30%
-----------------------------------------------------------------------------
     (14)   TYPE OF REPORTING PERSON (see instructions)
            OO - limited liability company
-----------------------------------------------------------------------------





CUSIP No. 87159A103                13D/A                Page 6 of 16 Pages

-----------------------------------------------------------------------------
     (1)    NAMES OF REPORTING PERSONS

            HealthCor Hybrid Offshore Master Fund, L.P.

-----------------------------------------------------------------------------
     (2)    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP(see instructions)
                                                                  (a)  [X]
                                                                  (b)  [ ]
-----------------------------------------------------------------------------
     (3)    SEC USE ONLY
-----------------------------------------------------------------------------
     (4)    SOURCE OF FUNDS
            AF
-----------------------------------------------------------------------------
     (5)    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS
            REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)                    [ ]
-----------------------------------------------------------------------------
     (6)    CITIZENSHIP OR PLACE OF ORGANIZATION
            Cayman Islands
-----------------------------------------------------------------------------
NUMBER OF      (7)  SOLE VOTING POWER
                    0

SHARES         --------------------------------------------------------------

BENEFICIALLY   (8)  SHARED VOTING POWER
                    138,022
OWNED BY       --------------------------------------------------------------

EACH           (9)  SOLE DISPOSITIVE POWER
                    0
REPORTING      --------------------------------------------------------------

PERSON WITH    (10) SHARED DISPOSITIVE POWER
                    138,022
-----------------------------------------------------------------------------
     (11)   AGGREGATE AMOUNT BENEFICIALLY OWNED
            BY EACH REPORTING PERSON
            138,022
-----------------------------------------------------------------------------
     (12)   CHECK BOX IF THE AGGREGATE AMOUNT
            IN ROW (11) EXCLUDES CERTAIN SHARES (see instructions)     [ ]
-----------------------------------------------------------------------------
     (13)   PERCENT OF CLASS REPRESENTED
            BY AMOUNT IN ROW (11)
            0.79%
-----------------------------------------------------------------------------
     (14)   TYPE OF REPORTING PERSON (see instructions)
            PN
-----------------------------------------------------------------------------





CUSIP No. 87159A103                13D/A                Page 7 of 16 Pages

-----------------------------------------------------------------------------
     (1)    NAMES OF REPORTING PERSONS

            HealthCor Hybrid Offshore GP, LLC

-----------------------------------------------------------------------------
     (2)    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP(see instructions)
                                                                  (a)  [X]
                                                                  (b)  [ ]
-----------------------------------------------------------------------------
     (3)    SEC USE ONLY
-----------------------------------------------------------------------------
     (4)    SOURCE OF FUNDS
            AF
-----------------------------------------------------------------------------
     (5)    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS
            REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)                    [ ]
-----------------------------------------------------------------------------
     (6)    CITIZENSHIP OR PLACE OF ORGANIZATION
            Cayman Islands
-----------------------------------------------------------------------------
NUMBER OF      (7)  SOLE VOTING POWER
                    0

SHARES         --------------------------------------------------------------

BENEFICIALLY   (8)  SHARED VOTING POWER
                    138,022
OWNED BY       --------------------------------------------------------------

EACH           (9)  SOLE DISPOSITIVE POWER
                    0
REPORTING      --------------------------------------------------------------

PERSON WITH    (10) SHARED DISPOSITIVE POWER
                    138,022
-----------------------------------------------------------------------------
     (11)   AGGREGATE AMOUNT BENEFICIALLY OWNED
            BY EACH REPORTING PERSON
            138,022
-----------------------------------------------------------------------------
     (12)   CHECK BOX IF THE AGGREGATE AMOUNT
            IN ROW (11) EXCLUDES CERTAIN SHARES (see instructions)     [ ]
-----------------------------------------------------------------------------
     (13)   PERCENT OF CLASS REPRESENTED
            BY AMOUNT IN ROW (11)
            0.79%
-----------------------------------------------------------------------------
     (14)   TYPE OF REPORTING PERSON (see instructions)
            OO - limited liability company
-----------------------------------------------------------------------------




CUSIP No. 87159A103                13D/A                Page 8 of 16 Pages

-----------------------------------------------------------------------------
     (1)    NAMES OF REPORTING PERSONS

            HealthCor Group, LLC

-----------------------------------------------------------------------------
     (2)    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP(see instructions)
                                                                  (a)  [X]
                                                                  (b)  [ ]
-----------------------------------------------------------------------------
     (3)    SEC USE ONLY
-----------------------------------------------------------------------------
     (4)    SOURCE OF FUNDS
            AF
-----------------------------------------------------------------------------
     (5)    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS
            REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)                    [ ]
-----------------------------------------------------------------------------
     (6)    CITIZENSHIP OR PLACE OF ORGANIZATION
            Delaware
-----------------------------------------------------------------------------
NUMBER OF      (7)  SOLE VOTING POWER
                    0

SHARES         --------------------------------------------------------------

BENEFICIALLY   (8)  SHARED VOTING POWER
                    882,731
OWNED BY       --------------------------------------------------------------

EACH           (9)  SOLE DISPOSITIVE POWER
                    0
REPORTING      --------------------------------------------------------------

PERSON WITH    (10) SHARED DISPOSITIVE POWER
                    882,731
-----------------------------------------------------------------------------
     (11)   AGGREGATE AMOUNT BENEFICIALLY OWNED
            BY EACH REPORTING PERSON
            882,731
-----------------------------------------------------------------------------
     (12)   CHECK BOX IF THE AGGREGATE AMOUNT
            IN ROW (11) EXCLUDES CERTAIN SHARES (see instructions)     [ ]
-----------------------------------------------------------------------------
     (13)   PERCENT OF CLASS REPRESENTED
            BY AMOUNT IN ROW (11)
            5.05%
-----------------------------------------------------------------------------
     (14)   TYPE OF REPORTING PERSON (see instructions)
            OO - limited liability company
-----------------------------------------------------------------------------





CUSIP No. 87159A103                13D/A                Page 9 of 16 Pages

-----------------------------------------------------------------------------
     (1)    NAMES OF REPORTING PERSONS

            HealthCor Capital, L.P.

-----------------------------------------------------------------------------
     (2)    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP(see instructions)
                                                                  (a)  [X]
                                                                  (b)  [ ]
-----------------------------------------------------------------------------
     (3)    SEC USE ONLY
-----------------------------------------------------------------------------
     (4)    SOURCE OF FUNDS
            AF
-----------------------------------------------------------------------------
     (5)    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS
            REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)                    [ ]
-----------------------------------------------------------------------------
     (6)    CITIZENSHIP OR PLACE OF ORGANIZATION
            Delaware
-----------------------------------------------------------------------------
NUMBER OF      (7)  SOLE VOTING POWER
                    0

SHARES         --------------------------------------------------------------

BENEFICIALLY   (8)  SHARED VOTING POWER
                    167,644
OWNED BY       --------------------------------------------------------------

EACH           (9)  SOLE DISPOSITIVE POWER
                    0
REPORTING      --------------------------------------------------------------

PERSON WITH    (10) SHARED DISPOSITIVE POWER
                    167,644
-----------------------------------------------------------------------------
     (11)   AGGREGATE AMOUNT BENEFICIALLY OWNED
            BY EACH REPORTING PERSON
            167,644
-----------------------------------------------------------------------------
     (12)   CHECK BOX IF THE AGGREGATE AMOUNT
            IN ROW (11) EXCLUDES CERTAIN SHARES (see instructions)     [ ]
-----------------------------------------------------------------------------
     (13)   PERCENT OF CLASS REPRESENTED
            BY AMOUNT IN ROW (11)
            0.96%
-----------------------------------------------------------------------------
     (14)   TYPE OF REPORTING PERSON (see instructions)
            PN
-----------------------------------------------------------------------------





CUSIP No. 87159A103                13D/A                Page 10 of 16 Pages

-----------------------------------------------------------------------------
     (1)    NAMES OF REPORTING PERSONS

            HealthCor, L.P.

-----------------------------------------------------------------------------
     (2)    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP(see instructions)
                                                                  (a)  [X]
                                                                  (b)  [ ]
-----------------------------------------------------------------------------
     (3)    SEC USE ONLY
-----------------------------------------------------------------------------
     (4)    SOURCE OF FUNDS
            AF
-----------------------------------------------------------------------------
     (5)    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS
            REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)                    [ ]
-----------------------------------------------------------------------------
     (6)    CITIZENSHIP OR PLACE OF ORGANIZATION
            Delaware
-----------------------------------------------------------------------------
NUMBER OF      (7)  SOLE VOTING POWER
                    0

SHARES         --------------------------------------------------------------

BENEFICIALLY   (8)  SHARED VOTING POWER
                    167,644
OWNED BY       --------------------------------------------------------------

EACH           (9)  SOLE DISPOSITIVE POWER
                    0
REPORTING      --------------------------------------------------------------

PERSON WITH    (10) SHARED DISPOSITIVE POWER
                    167,644
-----------------------------------------------------------------------------
     (11)   AGGREGATE AMOUNT BENEFICIALLY OWNED
            BY EACH REPORTING PERSON
            167,644
-----------------------------------------------------------------------------
     (12)   CHECK BOX IF THE AGGREGATE AMOUNT
            IN ROW (11) EXCLUDES CERTAIN SHARES (see instructions)     [ ]
-----------------------------------------------------------------------------
     (13)   PERCENT OF CLASS REPRESENTED
            BY AMOUNT IN ROW (11)
            0.96%
-----------------------------------------------------------------------------
     (14)   TYPE OF REPORTING PERSON (see instructions)
            PN
-----------------------------------------------------------------------------





CUSIP No. 87159A103                13D/A                Page 11 of 16 Pages

-----------------------------------------------------------------------------
     (1)    NAMES OF REPORTING PERSONS

            Arthur Cohen

-----------------------------------------------------------------------------
     (2)    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP(see instructions)
                                                                  (a)  [X]
                                                                  (b)  [ ]
-----------------------------------------------------------------------------
     (3)    SEC USE ONLY
-----------------------------------------------------------------------------
     (4)    SOURCE OF FUNDS
            AF
-----------------------------------------------------------------------------
     (5)    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS
            REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)                    [ ]
-----------------------------------------------------------------------------
     (6)    CITIZENSHIP OR PLACE OF ORGANIZATION
            United States
-----------------------------------------------------------------------------
NUMBER OF      (7)  SOLE VOTING POWER
                    0

SHARES         --------------------------------------------------------------

BENEFICIALLY   (8)  SHARED VOTING POWER
                    882,731
OWNED BY       --------------------------------------------------------------

EACH           (9)  SOLE DISPOSITIVE POWER
                    0
REPORTING      --------------------------------------------------------------

PERSON WITH    (10) SHARED DISPOSITIVE POWER
                    882,731
-----------------------------------------------------------------------------
     (11)   AGGREGATE AMOUNT BENEFICIALLY OWNED
            BY EACH REPORTING PERSON
            882,731
-----------------------------------------------------------------------------
     (12)   CHECK BOX IF THE AGGREGATE AMOUNT
            IN ROW (11) EXCLUDES CERTAIN SHARES (see instructions)     [ ]
-----------------------------------------------------------------------------
     (13)   PERCENT OF CLASS REPRESENTED
            BY AMOUNT IN ROW (11)
            5.05%
-----------------------------------------------------------------------------
     (14)   TYPE OF REPORTING PERSON (see instructions)
            IN
-----------------------------------------------------------------------------





CUSIP No. 87159A103                13D/A                Page 12 of 16 Pages

-----------------------------------------------------------------------------
     (1)    NAMES OF REPORTING PERSONS

            Joseph Healey

-----------------------------------------------------------------------------
     (2)    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP(see instructions)
                                                                  (a)  [X]
                                                                  (b)  [ ]
-----------------------------------------------------------------------------
     (3)    SEC USE ONLY
-----------------------------------------------------------------------------
     (4)    SOURCE OF FUNDS
            AF
-----------------------------------------------------------------------------
     (5)    CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS
            REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)                    [ ]
-----------------------------------------------------------------------------
     (6)    CITIZENSHIP OR PLACE OF ORGANIZATION
            United States
-----------------------------------------------------------------------------
NUMBER OF      (7)  SOLE VOTING POWER
                    0
SHARES         --------------------------------------------------------------

BENEFICIALLY   (8)  SHARED VOTING POWER
                    882,731
OWNED BY       --------------------------------------------------------------

EACH           (9)  SOLE DISPOSITIVE POWER
                    0
REPORTING      --------------------------------------------------------------

PERSON WITH    (10) SHARED DISPOSITIVE POWER
                    882,731
-----------------------------------------------------------------------------
     (11)   AGGREGATE AMOUNT BENEFICIALLY OWNED
            BY EACH REPORTING PERSON
            882,731
-----------------------------------------------------------------------------
     (12)   CHECK BOX IF THE AGGREGATE AMOUNT
            IN ROW (11) EXCLUDES CERTAIN SHARES (see instructions)     [ ]
-----------------------------------------------------------------------------
     (13)   PERCENT OF CLASS REPRESENTED
            BY AMOUNT IN ROW (11)
            5.05%
-----------------------------------------------------------------------------
     (14)   TYPE OF REPORTING PERSON (see instructions)
            IN
-----------------------------------------------------------------------------




CUSIP No. 87159A103                13D/A                 Page 13 of 16 Pages

                                Explanatory Note

This  Amendment No. 10 (the "Amendment") hereby amends the Schedule 13D filed by
HealthCor Management, L.P., HealthCor Associates, LLC, HealthCor Offshore, Ltd.,
HealthCor  Hybrid Offshore, Ltd., HealthCor Group, LLC, HealthCor Capital, L.P.,
HealthCor,  L.P.,  Joseph Healy and Arthur Cohen on August 8, 2007 (as corrected
by  the amendment filed on August 9, 2007), as previously amended (the "Original
Schedule  13D"  and  collectively  with this Amendment, the "Schedule 13D") with
regard to the shares of Common Stock of Trimeris, Inc. (the "Issuer"), par value
$0.001 (the "Shares").

This  Amendment is being filed solely to reflect the effects of the transactions
disclosed by the Issuer in its Current Report on Form 8-K filed November 3, 2011
(the  "Form  8-K"),  including:  (A) the one-for-five reverse stock split of the
Issuer's  issued and outstanding common stock, (B) the issuance of shares at the
effective  time  of  the  transaction  described in the Form 8-K pursuant to the
Agreement  and  Plan  of  Merger  and  Reorganization  by  and among the Issuer,
Synageva  BioPharma Corp., a Delaware corporation, and Tesla Merger Sub, Inc., a
Delaware corporation and a wholly-owned subsidiary of the Issuer (the "Merger");
and  (C)  the  change  of  the  Issuer's  name  to "Synageva BioPharma Corp." in
connection with the transactions described above.

Item 1 of the Original Schedule 13D is hereby amended as follows:

         Item 1(a).     Name of Issuer:
                        Synageva BioPharma Corp.

         Item 1(b).     Address of Issuer's Principal Executive Offices:
                        128 Spring Street, Suite 520, Lexington, MA  02421

Item 5 of the Original Schedule 13D is hereby amended as follows:

         Item  5(a).  Collectively,  the  Reporting  Persons beneficially own an
         aggregate  of  882,731  shares  of Common Stock. This amount represents
         approximately  5.05%  of  the  Issuer's outstanding common stock, based
         upon   17,490,445   shares  of  Common  Stock  issued  and  outstanding
         immediately following the Merger (and giving effect to the one-for-five
         reverse stock split as disclosed in the Form 8-K).

         Of this amount:

         (i)  HealthCor  Offshore  Master  Fund, L.P. is the beneficial owner of
         577,065 shares of Common Stock;

         (ii)  HealthCor  Hybrid  Offshore  Master  Fund, L.P. is the beneficial
         owner of 138,022 shares of Common Stock;

         (iii)  HealthCor,  L.P.  is  the  beneficial owner of 167,644 shares of
         Common  Stock  (collectively,  the  entities  in  (i) through (iii) are
         referred to as the "Funds");





CUSIP No. 87159A103                13D/A                 Page 14 of 16 Pages

         (iv)  HealthCor  Offshore  GP,  LLC is the general partner of HealthCor
         Offshore  Master Fund, L.P. Accordingly, HealthCor Offshore GP, LLC may
         be  deemed  to  beneficially  own  the  shares of Common Stock that are
         beneficially  owned  by  HealthCor Offshore Master Fund, L.P. HealthCor
         Group,  LLC  is  the general partner of HealthCor Offshore GP, LLC and,
         therefore, may be deemed to beneficially own the shares of Common Stock
         that are beneficially owned by HealthCor Offshore Master Fund, L.P.;

         (v)  HealthCor  Hybrid  Offshore  GP,  LLC  is  the  general partner of
         HealthCor  Hybrid  Offshore  Master  Fund,  L.P. Accordingly, HealthCor
         Hybrid Offshore GP, LLC may be deemed to beneficially own the shares of
         Common  Stock  that are beneficially owned by HealthCor Hybrid Offshore
         Master  Fund,  L.P.  HealthCor  Group,  LLC  is  the general partner of
         HealthCor  Hybrid  Offshore  GP,  LLC  and, therefore, may be deemed to
         beneficially own the shares of Common Stock that are beneficially owned
         by HealthCor Hybrid Offshore Master Fund, L.P.;

         (vi)  By virtue of its position as the investment manager of the Funds,
         HealthCor  Management, L.P. may be deemed a beneficial owner of all the
         shares of Common Stock owned by the Funds. HealthCor Associates, LLC is
         the  general partner of HealthCor Management, L.P. and thus may also be
         deemed  to  beneficially  own  the  shares  of  Common  Stock  that are
         beneficially owned by the Funds.

         (vii)  HealthCor Group LLC is the general partner of HealthCor Capital,
         L.P.,  which  is  in  turn  the  general  partner  of  HealthCor,  L.P.
         Accordingly,  each  of  HealthCor Capital L.P. and HealthCor Group, LLC
         may  be  deemed to beneficially own the shares of Common Stock that are
         beneficially owned by HealthCor, L.P.

         (viii)  As  the Managers of HealthCor Associates, LLC, Arthur Cohen and
         Joseph Healey exercise both voting and investment power with respect to
         the  shares  of Common Stock reported herein, and therefore each may be
         deemed a beneficial owner of such Common Stock.

         The  filing of this Schedule 13D shall not be construed as an admission
         that any of the Reporting Persons is, for the purposes of Section 13(d)
         or  13(g)  of  the  Securities  Exchange  Act  of 1934, as amended, the
         beneficial  owner  of  any  of  the shares of Common Stock owned by the
         Funds.  Pursuant  to  Rule  13d-4, each of the Reporting Persons hereby
         disclaims  any beneficial ownership of any such securities in excess of
         their actual pecuniary interest therein.

         Item  5(b). The information in Items 7 through 10 of each cover page to
         this Schedule 13D is incorporated by reference into this Item 5(b).

         Item 5(c). The Reporting Persons have effected no transactions relating
         to the Common Stock during the past 60 days.

         Items (d)-(e).  Inapplicable.





CUSIP No. 87159A103                13D/A                Page 15 of 16 Pages

                                 SIGNATURE

After  reasonable  inquiry and to the best of my knowledge and belief, I certify
that the information set forth in this statement is true, complete and correct.

DATED:  November 7, 2011

                 HEALTHCOR MANAGEMENT, L.P.

                           By: HealthCor Associates, LLC, its general partner

                           By: /s/ John H. Coghlin
                           -------------------------------------
                           Name: John H. Coghlin
                           Title: General Counsel

                HEALTHCOR CAPITAL, L.P., for itself and as general  partner
                on behalf of HEALTHCOR L.P.

                           By: HealthCor Group, LLC, its general partner

                           By: /s/ John H. Coghlin
                           -------------------------------------
                           Name: John H. Coghlin
                           Title: General Counsel

                 HEALTHCOR OFFSHORE GP, LLC, for itself and as general partner
                 of behalf of HEALTHCOR OFFSHORE MASTER FUND, L.P.


                           By: HealthCor Group, LLC, its general partner

                           By: /s/ John H. Coghlin
                           -------------------------------------
                           Name:  John H. Coghlin
                           Title:  General Counsel

                 HEALTHCOR HYBRID OFFSHORE GP, LLC, for itself and as general
                 partner of behalf of HEALTHCOR HYBRID OFFSHORE MASTER
                 FUND, L.P.


                           By: HealthCor Group, LLC, its general partner

                           By: /s/ John H. Coghlin
                           -------------------------------------
                           Name:  John H. Coghlin
                           Title:  General Counsel

                 HEALTHCOR ASSOCIATES, LLC

                           By: /s/ John H. Coghlin
                           -------------------------------------
                           Name: John H. Coghlin
                           Title: General Counsel





CUSIP No. 87159A103                13G                Page 16 of 16 Pages

                 HEALTHCOR GROUP, LLC

                           By: /s/ John H. Coghlin
                           -------------------------------------
                           Name: John H. Coghlin
                           Title: General Counsel

                 JOSEPH HEALEY, Individually

                           /s/ Joseph Healey
                           -----------------------------------

                 ARTHUR COHEN, Individually

                           /s/ Arthur Cohen
                           -----------------------------------