Exhibit 5.1

August 4, 2005




Gene Logic Inc.
610 Professional Drive
Gaithersburg, Maryland 20879

                  Re:      Registration Statement on Form S-8
                           ----------------------------------

Ladies and Gentlemen:

                  We have acted as counsel for Gene Logic Inc. (the
"Corporation") in connection with a registration statement on Form S-8 of the
Corporation to be filed with the Securities and Exchange Commission (the
"Registration Statement"), pertaining to the registration of 325,000 shares (the
"Shares") of common stock, par value $.01 per share of the Corporation ("Common
Stock") for issuance and sale pursuant to the Corporation's Amended and Restated
1997 Non-Employee Directors' Stock Option Plan (the "Plan").

                  As counsel for the Corporation, we are familiar with its
Certificate of Incorporation and Bylaws. We have examined the Registration
Statement substantially in the form in which it is to become effective, the
Plan, and the prospectus to be provided to Plan participants. We have further
examined and relied upon a certificate of the Secretary of State of the State of
Delaware to the effect that the Corporation is duly incorporated and existing
under the laws of the State of Delaware and is in good standing and duly
authorized to transact business in the State of Delaware.

                  We have also examined and relied upon such corporate records
of the Corporation and other documents and certificates with respect to factual
matters as we have deemed necessary to render the opinion expressed herein. With
respect to the documents we have reviewed, we have assumed, without independent
verification, the genuineness of all signatures, the authenticity of all
documents submitted to us as originals, and the conformity with originals of all
documents submitted to us as copies and the authenticity of such original
documents. As to any facts material to this opinion that we did not
independently establish or verify, we have relied upon statements and
representations of officers and other representatives of the Corporation.







                  In rendering our opinion, we have also assumed that the
Corporation shall have sufficient authorized and unissued shares of Common Stock
available at the time of each issuance of the Shares and that the relevant
provisions of the Certificate of Incorporation and Bylaws of the Corporation and
the Delaware General Corporation Law in effect at the time of issuance of any of
the Shares will not differ in any relevant respect from the analogous provisions
of the Certificate of Incorporation and Bylaws of the Corporation and the
Delaware General Corporation Law in effect as of the date of this opinion and
that no additional relevant provisions shall have been added subsequent to the
date hereof.

                  Based upon and subject to the foregoing, we are of the opinion
that when sold, issued and paid for as contemplated in the Plan, the Shares will
be duly authorized, validly issued, fully paid and nonassessable.

                  This letter is strictly limited to the matters expressly set
forth herein and no statements or opinions should be inferred beyond such
matters. It expresses our opinion with respect to the Delaware General
Corporation Law governing matters such as the authorization and issuance of
stock (without regard to the principles of conflicts of laws thereof) and is
based upon and limited to the Delaware General Corporation Law as in effect as
of the date hereof. We assume no obligation to update the opinion set forth
herein. This opinion does not extend to the securities or "blue sky" laws of
Delaware, Maryland or any other state, to federal securities laws or to other
laws.

                  We hereby consent to the filing of this opinion as an exhibit
to the Registration Statement. In giving this consent, we do not thereby admit
that we are within the category of persons whose consent is required under
Section 7 of the Securities Act of 1933, as amended, or the Rules and
Regulations of the Securities and Exchange Commission thereunder. This opinion
is intended solely for your use in connection with the transactions described
above. It may not be relied upon for any other purpose without our prior written
consent.

                                                     Very truly yours,

                                                     /s/ Venable LLP