Exhibit 99.1 Charles River Laboratories Announces Fourth-Quarter and Full-Year 2005 Results WILMINGTON, Mass.--(BUSINESS WIRE)--Feb. 8, 2006--Charles River Laboratories International, Inc. (NYSE:CRL): - Q4 Sales Reach $291 Million and 2005 Sales Exceed $1.1 Billion - - Q4 GAAP Earnings Per Share of $0.69 and $0.59 on a Non-GAAP Basis - - 2005 GAAP Earnings Per Share of $1.96 and $2.29 on a Non-GAAP Basis - - Reaffirms 2006 Guidance - Charles River Laboratories International, Inc. (NYSE:CRL) today reported fourth-quarter and full-year 2005 financial results. Net sales for the fourth quarter of 2005 increased 22.3% to $291.2 million, including a negative foreign exchange effect of 2.8%, compared to $238.1 million reported in the fourth quarter of 2004. The increase was due primarily to a strong performance by the Preclinical Services business, which benefited from continuing robust demand for outsourced preclinical services and the October 2004 acquisition of Inveresk Research Group, as well as increased sales of North America Research Models and In Vitro products. Net income on a GAAP basis was $50.4 million, or $0.69 per diluted share, in the fourth quarter of 2005, compared to $20.1 million, or $0.32 per diluted share, in the fourth quarter of 2004. On a non-GAAP basis, net income for the fourth quarter increased to $42.9 million compared to $31.2 million in the fourth quarter of 2004, an increase of 37.6%. Non-GAAP earnings per diluted share for the fourth quarter of 2005 increased 22.9% to $0.59, compared to $0.48 per diluted share in the fourth quarter of 2004. Non-GAAP results in the fourth quarter of 2005 exclude the impact of charges related to the acquisition of Inveresk, the impairment of fixed assets, intangible assets and lease obligations, severance costs, accelerated vesting of certain stock options, and a net benefit from repatriation of accumulated income earned outside the United States under the American Jobs Creation Act of 2004. For fiscal 2005, net sales increased 46.3% to $1.12 billion from $766.9 million in 2004. Net income on a GAAP basis was $142.0 million, or $1.96 per diluted share, compared to $89.8 million, or $1.68 per diluted share, in 2004. On a non-GAAP basis, net income for 2005 increased 55.4% to $165.8 million, compared to $106.7 million in 2004. Non-GAAP earnings per diluted share were $2.29, compared to $1.98 per diluted share in 2004, an increase of 15.7%. Non-GAAP results for 2005 exclude the impact of charges related to the acquisition of Inveresk, the impairment of fixed assets, intangible assets and lease obligations, severance costs, accelerated vesting of certain stock options, and the net benefit from repatriation of accumulated income earned outside the United States. James C. Foster, Chairman, President and Chief Executive Officer said, "Throughout 2005, our focus remained on fully supporting our customers while improving operating efficiency as we integrated the Inveresk operations with Charles River. We were very pleased with our Preclinical Services sales results, and ended the year with continuing robust demand for our services, especially in toxicology. We significantly improved the Preclinical non-GAAP operating margin, which on a year-over-year basis, increased to 21.9% from 17.4% in 2004. Our focus on Clinical Services' operations resulted in a non-GAAP operating margin increase to 15.3% for 2005 from 12.1% in the first quarter of 2005. And in December, we were pleased to see higher sales of research models. North America sales were up 12.7% for the quarter, which we believe is an indicator of demand for 2006." "We are enthusiastic about 2006 as we focus on internal development and organic growth. The demand for drug development products and outsourced services is continuing to grow, and we are expanding our facilities to accommodate our customers' needs. Our West Coast research model facility expansion, which is scheduled to open in phases from late 2006 to mid-2007, will provide additional production capacity and needed space for preconditioning services. In Preclinical Services, we opened a large expansion in Montreal in early 2005 which is currently operating near capacity. In 2006, we will have additional capacity coming on line in a number of our existing facilities beginning with Edinburgh at the end of the first quarter, and ending with a new state-of-the-art facility in Massachusetts late in the fourth quarter. Another new facility will open in Nevada in mid-2007. These investments in our physical plant will significantly expand our preclinical capacity, positioning us to support our clients as they increase their use of strategic outsourced services. Our discussions with pharmaceutical and biotechnology clients confirm our belief that they will continue to outsource, and I'm very pleased to say that in the fourth quarter, we signed an amendment to an existing preferred provider agreement with a large biotechnology client which provides for additional services and dedicated space," he said. Fourth-Quarter Actions As the Company announced previously, a one-time, primarily non-cash charge was recorded in the fourth quarter of 2005 for impairment of fixed assets, intangible assets and lease obligations and for severance costs related to headcount reductions. The charges related to the planned closure of Preclinical Services Wisconsin, one of the Company's two Interventional and Surgical Services facilities; exiting one floor of the Company's Cary, North Carolina, Clinical Services facility; and severance costs resulting from the Wisconsin closure and headcount reductions in the Clinical Services and Research Models and Services (RMS) businesses. Also as previously announced, the Company recorded a one time, non-cash charge for the accelerated vesting of certain stock options. The net after tax effect of the fourth-quarter charges was $6.2 million, or $0.08 per diluted share. Also in the fourth quarter of 2005, the Company repatriated $148.0 million of its accumulated income earned outside the United States (U.S.) in a distribution that qualified for the reduced tax rate under the American Jobs Creation Act of 2004. At the time of the Inveresk acquisition, and in anticipation of repatriating Inveresk's pre-acquisition non-U.S. earnings, the Company recorded a $41.0 million deferred tax liability using its regular U.S. corporate tax rate of 35%. During the fourth quarter of 2005, the Company recognized a one-time net after-tax benefit of $26.2 million, or $0.36 per diluted share; this benefit incorporates the impact of the repatriation, a tax reorganization, and the decision not to repatriate the remaining pre-acquisition non-U.S. Inveresk earnings. The Company decided not to repatriate the remaining pre-acquisition non-U.S. Inveresk earnings due to increased demand for cash outside the U.S. to fund expansion of the Company's preclinical facilities and increased United Kingdom pension funding requirements. Business Segments Results Research Models and Services Fourth-quarter 2005 net sales for the RMS segment of the business were $125.6 million compared to $119.0 million in the previous year, an increase of 5.5% including a negative foreign exchange effect of 3.5%. Growth was due primarily to North America Research Model sales, which increased 12.7%, and In Vitro products, which gained 18.7%. The large animal business also reported significantly higher sales growth of 30.9%. Sales growth was partially offset by the negative effect of foreign exchange in our European and Japanese operations, and by the services businesses, particularly Transgenic Services sales in the United States. Primarily as a result of lower services sales, the effect of an additional week in the fourth quarter, and higher fuel costs, the gross margin declined slightly to 40.8% from 41.0% reported in the fourth quarter of 2004. However, higher fourth-quarter sales resulted in an operating margin improvement to 30.0% from 29.2% in the same period in 2004. When excluding $0.4 million of severance costs incurred as a result of headcount reductions, the non-GAAP operating margin was 30.3%. Charles River's results are reported on a fiscal year basis which is the twelve-month period ending on the last Saturday in December. As a result, the Company periodically reports a 53-week year, with the additional week included in the fourth quarter. This was the case in 2005. For fiscal 2005, RMS net sales were $503.2 million, an increase of 5.6% from the $476.7 million reported in 2004. Sales of North America Research Models gained 10.3% for the year and In Vitro Detection rose 23.7%, offset in part by slower growth rates for other businesses in the segment, especially Research Model Services. The gross margin was 42.9% compared to 43.4% in 2004, and the operating margin was 31.8% compared to 32.0% in 2004. Preclinical Services Net sales for the Preclinical Services segment were $132.7 million in the fourth quarter of 2005, an increase of 40.0% from the $94.8 million reported in the fourth quarter of 2004. The increase was due to continuing strong demand for outsourced development services and the acquisition of Inveresk. The segment's gross margin declined to 32.8% from 33.1% in the fourth quarter of 2004. Operating income was $9.1 million in the fourth quarter of 2005, compared to $4.8 million last year. The operating margin was 6.9% compared to 5.1% in the fourth quarter of 2004, with the increase due primarily to higher sales and improved capacity utilization. When excluding amortization of $11.1 million related to the Inveresk acquisition and charges of $6.5 million due to the planned closure of Preclinical Services Wisconsin, the fourth-quarter non-GAAP operating margin rose to 20.1% from 18.3% in the fourth quarter of 2004. On a sequential basis, the Preclinical fourth-quarter non-GAAP operating margin declined to 20.1% from 24.0% in the third quarter of 2005. The primary drivers of the margin decrease were the impact of the 53rd week, the negative effect of foreign exchange on operating costs in Montreal and an increase in period costs. For fiscal 2005, Preclinical net sales were $488.5 million compared to $266.0 million in 2004, an increase of 83.7%. The gross margin for 2005 rose to 34.7% from 32.4% in 2004, and the operating margin was 12.0% compared to 12.6% in 2004. When excluding amortization of $41.8 million related to the Inveresk acquisition and the fourth-quarter charges, the non-GAAP operating margin increased to 21.9% from 17.4% in 2004, a gain of 450 basis points. Clinical Services For the fourth quarter of 2005, net sales for the Clinical Services segment were $32.8 million. The gross margin was 32.6% and the operating margin was 0.5%. When excluding amortization of $3.1 million related to the Inveresk acquisition and fourth-quarter charges of $1.8 million resulting from the leasehold impairment and headcount reduction, the non-GAAP operating margin was 15.5%. For fiscal 2005, Clinical net sales were $130.5 million, the gross margin was 33.3%, and the operating margin was 4.6%. When excluding amortization of $12.1 million related to the Inveresk acquisition and the fourth-quarter charges, the non-GAAP operating margin was 15.3%. Backlog The backlog for Preclinical and Clinical Services at December 31, 2005, was $448 million compared to $431 million at the end of the third quarter and $425 million at the end of 2004. Net bookings increased 11.7% to $184 million and the net book-to-bill ratio rose to 1.11 from 1.06 in the third quarter of 2005. The Company does not report backlog for the RMS business segment because turnaround time from placement to completion of orders, both for products and services, is rapid. Stock Repurchase Program As previously disclosed, Charles River presently has an authorization to repurchase $100.0 million of its common stock. The stock purchases will be made from time to time on the open market, through block trades or otherwise in compliance with Rule 10b-18 of the federal securities laws. Depending on market conditions and other factors, these repurchases may be commenced or suspended at any time or from time to time without prior notice. Funds for the repurchases are expected to come from cash on hand or cash generated by operations. As of December 31, 2005, the Company had repurchased 396,000 shares at a total cost of $17.5 million. Through February 8, 2006, the Company purchased an additional 128,400 shares at a total cost of $5.7 million. There are currently no specific plans for the shares that have been or may be purchased under the program. As of December 31, 2005, Charles River had approximately 72.4 million shares of common stock outstanding. 2006 Outlook The following forward-looking guidance is based on current foreign exchange rates. The Company reaffirmed its expectation that 2006 revenue growth will be in a range of 7% to 9%, including a 1% negative effect from foreign exchange. The Company also reaffirmed its expectation that GAAP earnings per diluted share for 2006, which include the effect of the implementation on January 1, 2006, of Statement of Financial Accounting Standards No. 123R (SFAS 123R), "Share-Based Payment," are expected to be in a range of $1.95 to $2.01. Non-GAAP earnings per diluted share are expected to be in a range of $2.34 to $2.40, and when excluding the effect of SFAS 123R, 2006 non-GAAP earnings per diluted share are expected to be in a range of $2.46 to $2.52, which is consistent with the Company's previous guidance. A reconciliation of GAAP to non-GAAP estimated earnings per diluted share is as follows: $ in Millions, Except Per Share Amounts 2006E 2006E EPS GAAP EPS $ 1.95-$2.01 Stock Option Expense $ 12.6 $ 0.12 EPS (excluding stock option expense) $ 2.07-$2.13 Inveresk Amortization $ 41.1 $ 0.38 Inveresk Compensation Charges $ 1.2 $ 0.01 NON-GAAP EPS (excluding stock option expense) $ 2.46-$2.52 Stock Option Expense $ 12.6 $ 0.12 NON-GAAP EPS (including stock option expense) $ 2.34-$2.40 Webcast Charles River Laboratories has scheduled a live webcast on Thursday, February 9, at 8:30 a.m. ET to discuss matters relating to this press release. To participate, please go to ir.criver.com and select the webcast link. You can also find the associated slide presentation and reconciliations to comparable GAAP measures on the website. The webcast will be available until 5:00 p.m. ET on February 17, 2006. Use of Non-GAAP Financial Measures This press release contains non-GAAP financial measures which exclude, among other items, amortization of intangible assets and other charges related to the Inveresk acquisition. We exclude these items from the non-GAAP financial measures because they are outside our normal operations. We believe that the inclusion of non-GAAP financial measures in this press release helps investors to gain a meaningful understanding of our core operating results and future prospects, and is consistent with how management measures and forecasts the Company's performance, especially when comparing such results to prior periods or forecasts. Non-GAAP results also allow investors to compare the Company's operations against the financial results of other companies in the industry who similarly provide non-GAAP results. The non-GAAP financial measures included in this press release are not meant to be considered superior to or a substitute for results of operations prepared in accordance with GAAP. Reconciliations of the non-GAAP financial measures used in this press release to the most directly comparable GAAP financial measures are set forth in the text of, and the accompanying exhibits to, this press release, and can also be found on the Company's website at ir.criver.com. Caution Concerning Forward-Looking Statements. This news release includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements may be identified by the use of words such as "anticipate," "believe," "expect," "will," "may," "estimate," "plan," "outlook," and "project" and other similar expressions that predict or indicate future events or trends or that are not statements of historical matters. These statements also include statements regarding the future demand for drug discovery and development products and services, including the outsourcing of these services; the impact of specific actions intended to improve overall operating efficiencies and profitability, particularly with respect to the Interventional and Surgical Services, Transgenic Services, and Clinical Services businesses; expectations regarding future stock option, restricted stock and other equity grants to the Company's employees and directors; the timing of the opening of new and expanded facilities; and Charles River's future performance as delineated in our forward-looking guidance, and particularly our expectations with respect to sales growth, efficiency improvements and operating synergies. Forward-looking statements are based on Charles River's current expectations and beliefs, and involve a number of risks and uncertainties that are difficult to predict and that could cause actual results to differ materially from those stated or implied by the forward-looking statements. Those risks and uncertainties include, but are not limited to: challenges arising from the integration of Inveresk Research Group; a decrease in research and development spending or a decrease in the level of outsourced services; acquisition integration risks; the ability to convert backlog to sales; special interest groups; contaminations; industry trends; new displacement technologies; USDA and FDA regulations; changes in law; continued availability of products and supplies; loss of key personnel; interest rate and foreign currency exchange rate fluctuations; changes in tax regulation and laws; changes in generally accepted accounting principles; and any changes in business, political, or economic conditions due to the threat of future terrorist activity in the U.S. and other parts of the world, and related U.S. military action overseas. A further description of these risks, uncertainties, and other matters can be found in the Risk Factors detailed in Charles River's Annual Report on Form 10-K as filed on March 9, 2005, as well as other filings we make with the Securities and Exchange Commission. Because forward-looking statements involve risks and uncertainties, actual results and events may differ materially from results and events currently expected by Charles River, and Charles River assumes no obligation and expressly disclaims any duty to update information contained in this news release except as required by law. About Charles River Laboratories Charles River Laboratories, based in Wilmington, Massachusetts, is a global provider of solutions that advance the drug discovery and development process. Our leading-edge products and services are designed to enable our clients to bring drugs to market faster and more efficiently. Backed by our rigorous, best-in-class procedures and our proven data collection, analysis and reporting capabilities, our products and services are organized into three categories spanning every step of the drug development pipeline: Research Models and Services, Preclinical Services, and Clinical Services. Charles River's customer base includes all of the major pharmaceutical companies and many biotechnology companies, government agencies and leading hospitals and academic institutions. Charles River's 8,400 employees serve clients in more than 50 countries. For more information on Charles River, visit our website at www.criver.com. CHARLES RIVER LABORATORIES INTERNATIONAL, INC. CONDENSED CONSOLIDATED STATEMENTS OF INCOME (UNAUDITED) (dollars in thousands, except for per share data) Three Months Ended Twelve Months Ended ----------------------- ----------------------- Dec. 31, Dec. 25, Dec. 31, Dec. 25, 2005 2004 2005 2004 Total net sales $ 291,155 $ 238,061 $1,122,228 $ 766,917 Cost of products sold and services provided 185,610 152,341 693,493 468,351 ----------- ----------- ----------- ----------- Gross margin 105,545 85,720 428,735 298,566 Selling, general and administrative 54,099 39,287 189,544 121,448 Amortization of intangibles 15,170 13,204 58,172 16,795 ----------- ----------- ----------- ----------- Operating income 36,276 33,229 181,019 160,323 Interest income (expense) (5,600) (4,572) (20,432) (8,521) Other, net 803 679 (174) 723 ----------- ----------- ----------- ----------- Income before income taxes and minority interests 31,479 29,336 160,413 152,525 Provision for income taxes (19,332) 9,171 16,576 61,156 ----------- ----------- ----------- ----------- Income before minority interests 50,811 20,165 143,837 91,369 Minority interests (393) (88) (1,838) (1,577) ----------- ----------- ----------- ----------- Net income $ 50,418 $ 20,077 $ 141,999 $ 89,792 =========== =========== =========== =========== Earnings per common share Basic $ 0.70 $ 0.33 $ 2.04 $ 1.81 Diluted $ 0.69 $ 0.32 $ 1.96 $ 1.68 Weighted average number of common shares outstanding Basic 71,775,081 60,341,786 69,730,056 49,601,021 Diluted 73,161,997 67,035,677 72,902,385 56,045,848 CHARLES RIVER LABORATORIES INTERNATIONAL, INC. CONDENSED CONSOLIDATED BALANCE SHEETS (UNAUDITED) (dollars in thousands) December 31, December 25, 2005 2004 Assets Current assets Cash and cash equivalents $ 114,821 $ 207,566 Trade receivables, net 203,274 201,794 Inventories 65,270 61,914 Other current assets 35,727 39,032 ------------ ------------ Total current assets 419,092 510,306 Property, plant and equipment, net 399,454 357,149 Goodwill, net 1,413,307 1,422,586 Other intangibles, net 199,148 256,294 Deferred tax asset 67,911 50,412 Other assets 34,708 30,088 ------------ ------------ Total assets $ 2,533,620 $ 2,626,835 ============ ============ Liabilities and Shareholders' Equity Current liabilities Current portion of long-term debt $ 80,195 $ 80,456 Accounts payable 30,447 28,672 Accrued compensation 40,358 46,037 Deferred income 116,302 117,490 Other current liabilities 88,110 76,460 ------------ ------------ Total current liabilities 355,412 349,115 Long-term debt 215,895 605,388 Other long-term liabilities 125,816 190,035 ------------ ------------ Total liabilities 697,123 1,144,538 ------------ ------------ Minority interests 9,718 9,792 Total shareholders' equity 1,826,779 1,472,505 ------------ ------------ Total liabilities and shareholders' equity $ 2,533,620 $ 2,626,835 ============ ============ CHARLES RIVER LABORATORIES INTERNATIONAL, INC. SELECTED BUSINESS SEGMENT INFORMATION (UNAUDITED) (dollars in thousands) Three Months Ended Twelve Months Ended ------------------- ------------------- Dec. 31, Dec. 25, Dec. 31, Dec. 25, 2005 2004 2005 2004 Research Models and Services Net sales $125,603 $119,017 $ 503,168 $476,668 Gross margin 51,288 48,852 215,649 206,797 Gross margin as a % of net sales 40.8% 41.0% 42.9% 43.4% Operating income 37,685 34,721 159,756 152,556 Operating income as a % of net sales 30.0% 29.2% 31.8% 32.0% Depreciation and amortization 5,216 4,760 20,016 17,872 Capital expenditures 7,367 11,194 24,742 26,559 Preclinical Services Net sales $132,709 $ 94,772 $ 488,549 $265,977 Gross margin 43,564 31,329 169,684 86,230 Gross margin as a % of net sales 32.8% 33.1% 34.7% 32.4% Operating income 9,116 4,815 58,594 33,622 Operating income as a % of net sales 6.9% 5.1% 12.0% 12.6% Depreciation and amortization 17,522 14,943 67,602 25,443 Capital expenditures 19,044 11,747 71,266 18,493 Clinical Services Net sales $ 32,843 $ 24,272 $ 130,511 $ 24,272 Gross margin 10,693 5,539 43,402 5,539 Gross margin as a % of net sales 32.6% 22.8% 33.3% 22.8% Operating income 152 731 6,005 731 Operating income as a % of net sales 0.5% 3.0% 4.6% 3.0% Depreciation and amortization 3,738 2,994 14,837 2,994 Capital expenditures 305 284 660 284 Unallocated Corporate Overhead $(10,677) $ (7,038)$ (43,336)$(26,586) Total Net sales $291,155 $238,061 $1,122,228 $766,917 Gross margin 105,545 85,720 428,735 298,566 Gross margin as a % of net sales 36.3% 36.0% 38.2% 38.9% Operating income 36,276 33,229 181,019 160,323 Operating income as a % of net sales 12.5% 14.0% 16.1% 20.9% Depreciation and amortization 26,476 22,697 102,455 46,309 Capital expenditures 26,716 23,225 96,668 45,336 CHARLES RIVER LABORATORIES INTERNATIONAL, INC. RECONCILIATION OF GAAP TO NON-GAAP SELECTED BUSINESS SEGMENT INFORMATION (UNAUDITED) (dollars in thousands) Three Months Ended Twelve Months Ended ---------------------- --------------------- Dec. 31, Dec. 25, Dec. 31, Dec. 25, 2005 2004 2005 2004 Research Models and Services Net sales $ 125,603 $ 119,017 $ 503,168 $ 476,668 Operating income 37,685 34,721 159,756 152,556 Operating income as a % of net sales 30.0% 29.2% 31.8% 32.0% Add back: Severance 365 - 365 - ---------- ---------- ---------- ---------- Operating income, excluding specified charges (Non-GAAP) 38,050 34,721 160,121 152,556 Non-GAAP operating income as a % of net sales 30.3% 29.2% 31.8% 32.0% Preclinical Services Net sales $ 132,709 $ 94,772 $ 488,549 $ 265,977 Operating income 9,116 4,815 58,594 33,622 Operating income as a % of net sales 6.9% 5.1% 12.0% 12.6% Add back: Amortization related to acquisition 11,113 9,610 41,788 9,610 Impairment 6,258 - 6,258 - Severance 252 - 252 - Proteomics write-off - 2,956 - 2,956 ---------- ---------- ---------- ---------- Operating income, excluding specified charges (Non-GAAP) 26,739 17,381 106,892 46,188 Non-GAAP operating income as a % of net sales 20.1% 18.3% 21.9% 17.4% Clinical Services Net sales $ 32,843 $ 24,272 $ 130,511 $ 24,272 Operating income 152 731 6,005 731 Operating income as a % of net sales 0.5% 3.0% 4.6% 3.0% Add back: Amortization related to acquisition 3,130 2,493 12,116 2,493 Impairment 1,573 - 1,573 - Severance 246 - 246 - ---------- ---------- ---------- ---------- Operating income, excluding specified charges (Non-GAAP) 5,101 3,224 19,940 3,224 Non-GAAP operating income as a % of net sales 15.5% 13.3% 15.3% 13.3% Unallocated Corporate Overhead $ (10,677)$ (7,038)$ (43,336)$ (26,586) Add back: Stock-based compensation related to acquisition 697 2,303 7,804 2,303 Acceleration of stock options 1,556 - 1,556 - Repatriation 1,305 - 1,305 - ---------- ---------- ---------- ---------- Unallocated corporate overhead, excluding specified charges (Non- GAAP) (7,119) (4,735) (32,671) (24,283) Total Net sales $ 291,155 $ 238,061 $1,122,228 $ 766,917 Operating income 36,276 33,229 181,019 160,323 Operating income as a % of net sales 12.5% 14.0% 16.1% 20.9% Add back: Amortization related to acquisition 14,243 12,103 53,904 12,103 Impairment 7,831 - 7,831 - Severance 863 - 863 - Stock-based compensation related to acquisition 697 2,303 7,804 2,303 Acceleration of stock options 1,556 - 1,556 - Repatriation 1,305 - 1,305 - Proteomics write-off - 2,956 - 2,956 ---------- ---------- ---------- ---------- Operating income, excluding specified charges (Non-GAAP) 62,771 50,591 254,282 177,685 Non-GAAP operating income as a % of net sales 21.6% 21.3% 22.7% 23.2% Charles River management believes that non-GAAP financial measures provide useful information to allow investors to gain a meaningful understanding of our core operating results and future prospects, without the effect of one-time charges, consistent with the manner in which management measures and forecasts the Company's performance. The non-GAAP financial measures included are not meant to be considered superior to, or a substitute for results of operations prepared in accordance with GAAP. The Company intends to continue to assess the potential value of reporting non-GAAP results consistent with applicable rules and regulations. CHARLES RIVER LABORATORIES INTERNATIONAL, INC. RECONCILIATION OF GAAP EARNINGS TO NON-GAAP EARNINGS (dollars in thousands, except for per share data) Three Months Ended Twelve Months Ended ----------------------- ----------------------- Dec. 31, Dec. 25, Dec. 31, Dec. 25, 2005 2004 2005 2004 Net income $ 50,418 $ 20,077 $ 141,999 $ 89,792 Add back: Amortization related to acquisition 14,243 12,103 53,904 12,103 Stock-based compensation related to acquisition 697 2,303 7,804 2,303 Tax effect (2,403) (4,791) (17,888) (4,791) ----------- ----------- ----------- ----------- Inveresk Charges 12,537 9,615 43,820 9,615 Impairment / Proteomics 7,831 2,956 7,831 2,956 Severance 863 - 863 - Minority Interest on Proteomics write- off - (345) - (345) Acceleration of stock options 1,556 - 1,556 - Deferred financing cost - 105 - 105 Tax effect (4,078) (1,210) (4,078) (1,210) ----------- ----------- ----------- ----------- Fourth-Quarter Actions 6,172 1,506 6,172 1,506 Repatriation fees 1,305 - 1,305 - Deferred tax reversal (28,271) - (28,271) - Deferred financing cost 2,155 - 2,155 - Tax effect (1,403) - (1,403) - ----------- ----------- ----------- ----------- Repatriation (26,214) - (26,214) - Deferred tax asset write-off - - - 7,900 Valuation allowance release - - - (2,111) ----------- ----------- ----------- ----------- European Reorganization - - - 5,789 ------------------------------------------------ Net income, excluding specified charges (Non-GAAP) $ 42,913 $ 31,198 $ 165,777 $ 106,702 =========== =========== =========== =========== Calculation of earnings per common share, excluding specified charges (Non-GAAP): Net income for purposes of calculating earnings per share, excluding specified charges (Non-GAAP) $ 42,913 $ 31,198 $ 165,777 $ 106,702 After-tax equivalent interest expense on 3.5% senior convertible debentures - 1,090 1,208 4,125 ----------- ----------- ----------- ----------- Income for purposes of calculating diluted earnings per share, excluding specified charges (Non-GAAP) $ 42,913 $ 32,288 $ 166,985 $ 110,827 =========== =========== =========== =========== Weighted average shares outstanding - Basic 71,775,081 60,341,786 69,730,056 49,601,021 Effect of dilutive securities: 3.5% senior convertible debentures - 4,759,455 1,462,474 4,759,455 Stock options and contingently issued restricted stock 1,241,411 1,593,121 1,424,740 1,346,665 Warrants 145,505 341,315 285,115 338,707 ----------- ----------- ----------- ----------- Weighted average shares outstanding - Diluted 73,161,997 67,035,677 72,902,385 56,045,848 =========== =========== =========== =========== Basic earnings per share $ 0.70 $ 0.33 $ 2.04 $ 1.81 Diluted earnings per share $ 0.69 $ 0.32 $ 1.96 $ 1.68 Basic earnings per share, excluding specified charges (Non-GAAP) $ 0.60 $ 0.52 $ 2.38 $ 2.15 Diluted earnings per share, excluding specified charges (Non-GAAP) $ 0.59 $ 0.48 $ 2.29 $ 1.98 Charles River management believes that non-GAAP financial measures provide useful information to allow investors to gain a meaningful understanding of our core operating results and future prospects, without the effect of one-time charges, consistent with the manner in which management measures and forecasts the Company's performance. The non-GAAP financial measures included are not meant to be considered superior to, or a substitute for results of operations prepared in accordance with GAAP. The Company intends to continue to assess the potential value of reporting non-GAAP results consistent with applicable rules and regulations. CONTACT: Charles River Laboratories International, Inc. Susan E. Hardy, 781-262-7616 Corporate Vice President, Investor Relations