UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                              Washington, DC 20549

                                  -------------

                                    FORM 8-K

                                 CURRENT REPORT
                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934

                Date of Report (Date of earliest event reported):
                     February 28, 2006 (February 22, 2006)

                                  -------------

                            LIFEPOINT HOSPITALS, INC.
             (Exact name of registrant as specified in its charter)

          Delaware                      0-51251                 20-1538254
(State or Other Jurisdiction          (Commission              (IRS Employer
      of Incorporation)               File Number)           Identification No.)


                   103 Powell Court, Suite 200
                       Brentwood, Tennessee                   37027
            (Address of principal executive offices)        (Zip Code)

                                 (615) 372-8500
              (Registrant's telephone number, including area code)

                                 Not applicable
          (Former Name or Former Address, if Changed Since Last Report)

Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions:

o    Written communication pursuant to Rule 425 under the Securities Act (17 CFR
     230.425)

o    Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
     240.14a-12)

o    Pre-commencement communications pursuant to Rule 14d-2(b) under the
     Exchange Act (17 CFR 240.14d-2(b))

o    Pre-commencement communications pursuant to Rule 13e-4(c) under the
     Exchange Act (17 CFR 240.13e-4(c))





Section 1    Registrant's Business and Operations

        Item 1.01.    Entry into a Material Definitive Agreement.

On February 22, 2006, the Compensation Committee (the "Compensation Committee")
of the Board of Directors of LifePoint Hospitals, Inc. (the "Company") approved
the grant of restricted stock awards and nonqualified stock options to the
Company's executive officers, as set forth in the following table:



                                                                                     
                                                           Shares of Restricted
Executive Officer                                             Stock Awarded         Stock Options Granted
- -----------------------------------------------           ------------------------------------------------
Kenneth C. Donahey
Chairman, President and Chief Executive Officer                   50,000                  100,000

Michael J. Culotta
Chief Financial Officer                                           22,500                   45,000

William F. Carpenter III
Executive Vice President, General Counsel and Secretary           22,500                   45,000

William M. Gracey
Chief Operating Officer                                           22,500                   45,000



The  Compensation   Committee  granted  the  restricted  stock  awards  and  the
nonqualified  stock  options  pursuant to the  Company's  Amended  and  Restated
Long-Term  Incentive Plan (the "Incentive  Plan"). The vesting of the restricted
stock awards granted to the executive  officers is subject to the achievement of
certain  predetermined  performance criteria. In addition to requiring continued
service as an employee  through December 31, 2008, the vesting of the restricted
stock  awards  requires the  realization  of certain  predetermined  amounts for
either annual revenue or annual  pre-tax income  (expressed as "EBITDA") for the
2006, 2007 or 2008 fiscal year. In the event that the shares do not vest because
the performance  conditions are not met, the unvested portion of the award shall
be forfeited and shall not carry over to any subsequent  year. The  nonqualified
stock  options  granted to the  executive  officers  vest in three equal  annual
installments on the first, second and third anniversaries of the date of grant.

On  February  22,  2006,  the  Compensation  Committee  certified  the  level of
achievement for fiscal 2005 in order to determine the annual bonus to be awarded
under the LifePoint Hospitals,  Inc. Executive  Performance  Incentive Plan (the
"Performance  Plan").  For fiscal 2005, the amount of the annual bonus award for
each  participant  under the  Performance  Plan was based on the  achievement of
certain  predetermined  performance  targets  related  to the  Company's  annual
revenue  and  annual  EBITDA.   While  the  maximum  amount  payable  under  the
Performance  Plan for fiscal 2005 for such  performance  would have been higher,
the Compensation Committee determined to reduce such payments, in its discretion
pursuant to the terms of the Performance Plan, to the following totals:

Executive Officer                                          Annual Bonus Payment
- ------------------------------------------------          ----------------------
Kenneth C. Donahey
Chairman, President and Chief Executive Officer                $647,125.08

Michael J. Culotta
Chief Financial Officer                                        $281,812.56

William F. Carpenter III
Executive Vice President, General Counsel and Secretary        $281,812.56

William M. Gracey
Chief Operating Officer                                        $281,812.56




On February 22, 2006, the Compensation Committee approved the following salary
increases for executive officers named in the Company's 2005 proxy statement:



                                                                                      
Executive Officer                                          Current Salary      % Increase     New Salary
- -------------------------------------------------------   -----------------------------------------------
Kenneth C. Donahey
Chairman, President and Chief Executive Officer               $775,000            3.2%         $800,000

Michael J. Culotta
Chief Financial Officer                                       $455,000           11.1%         $500,000

William F. Carpenter III
Executive Vice President, General Counsel and Secretary       $455,000           11.1%         $500,000

William M. Gracey
Chief Operations Officer                                      $455,000           11.1%         $500,000

Jone Law Koford
Division President                                            $355,000            2.8%         $365,000



On February  22,  2006,  the  Compensation  Committee  also  designated  Messrs.
Donahey,  Culotta,  Carpenter  and  Gracey  as the  executive  officers  who are
eligible  to receive an annual  bonus  under the  Performance  Plan for the 2006
fiscal  year.  The amount of the annual  bonus  award for each  participant  for
fiscal  2006  will  be  based  on  the  achievement  of  certain   predetermined
performance  targets related to the Company's  annual revenue and annual EBITDA,
subject to reduction by the Compensation  Committee,  in its discretion pursuant
to the terms of the Performance Plan.

Section 9    Financial Statements and Exhibits.

        Item 9.01.   Financial Statements and Exhibits.

                    (d) Exhibits.

                    10.1 Amended and  Restated  1998  Long-Term  Incentive  Plan
                         incorporated  by reference from exhibits to the Current
                         Report on Form 8-K of LifePoint  Hospitals,  Inc., File
                         No. 000-51251, filed July 7, 2005;

                    10.2 Form of  LifePoint  Hospital's  Inc.  Restricted  Stock
                         Award Agreement incorporated by reference from exhibits
                         to the  Quarterly  Report  on Form  10-Q  of  LifePoint
                         Hospitals,  Inc.  for the quarter  ended June 30, 2005,
                         File No. 000-51251;

                    10.3 Form of LifePoint  Hospital's Inc.  Nonqualified  Stock
                         Option   Agreement   incorporated   by  reference  from
                         exhibits  to the  Quarterly  Report  on  Form  10-Q  of
                         LifePoint  Hospitals,  Inc. for the quarter  ended June
                         30, 2005, File No. 000-51251; and

                    10.4 LifePoint   Hospitals,   Inc.   Executive   Performance
                         Incentive Plan  incorporated by reference from exhibits
                         to  the  Current   Report  on  Form  8-K  of  LifePoint
                         Hospitals,  Inc.,  File No.  000-29818,  filed  May 16,
                         2002.





SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.


Date: February 28, 2006                         LIFEPOINT HOSPITALS, INC.

                                                By: /s/  Michael J. Culotta
                                                    ----------------------------
                                                    Michael J. Culotta
                                                    Chief Financial Officer










                                  EXHIBIT INDEX

Exhibit
Number    Description of Exhibits
- ------    -----------------------

 10.1     Amended and Restated 1998  Long-Term  Incentive Plan  incorporated  by
          reference from exhibits to the Current Report on Form 8-K of LifePoint
          Hospitals, Inc., File No. 000-51251, filed July 7, 2005;

 10.2     Form of LifePoint  Hospital's  Inc.  Restricted  Stock Award Agreement
          incorporated  by reference  from exhibits to the  Quarterly  Report on
          Form 10-Q of LifePoint Hospitals,  Inc. for the quarter ended June 30,
          2005, File No. 000-51251;

 10.3     Form of LifePoint Hospital's Inc.  Nonqualified Stock Option Agreement
          incorporated  by reference  from exhibits to the  Quarterly  Report on
          Form 10-Q of LifePoint Hospitals,  Inc. for the quarter ended June 30,
          2005, File No. 000-51251; and

 10.4     LifePoint  Hospitals,   Inc.  Executive   Performance  Incentive  Plan
          incorporated  by reference from exhibits to the Current Report on Form
          8-K of LifePoint  Hospitals,  Inc., File No. 000-29818,  filed May 16,
          2002.